-
1
-
-
0020216124
-
Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome
-
Nusse, R. and Varmus, H.E. Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome. Cell 1982, 31: 99-109.
-
(1982)
Cell
, vol.31
, pp. 99-109
-
-
Nusse, R.1
Varmus, H.E.2
-
2
-
-
0031456158
-
Wnt signaling: A common theme in animal development
-
Cadigan, K.M. and Nusse, R. Wnt signaling: a common theme in animal development. Genes Dev 1997, 11: 3286-305.
-
(1997)
Genes Dev
, vol.11
, pp. 3286-3305
-
-
Cadigan, K.M.1
Nusse, R.2
-
3
-
-
0037737728
-
A role for Wnt signalling in self-renewal of haematopoietic stem cells
-
Reya, T., Duncan, A.W., Ailles, L. et al. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature 2003, 423: 409-14.
-
(2003)
Nature
, vol.423
, pp. 409-414
-
-
Reya, T.1
Duncan, A.W.2
Ailles, L.3
-
4
-
-
0032406715
-
Mechanisms of Wnt signaling in development
-
Wodarz, A. and Nusse, R. Mechanisms of Wnt signaling in development. Annu Rev Cell Dev Biol 1998, 14: 59-88.
-
(1998)
Annu Rev Cell Dev Biol
, vol.14
, pp. 59-88
-
-
Wodarz, A.1
Nusse, R.2
-
5
-
-
4344584730
-
WNT and beta-catenin signalling: Diseases and therapies
-
Moon, R.T., Kohn, A.D., De Ferrari, G.V. and Kaykas, A. WNT and beta-catenin signalling: diseases and therapies. Nat Rev Genet 2004, 5: 691-701.
-
(2004)
Nat Rev Genet
, vol.5
, pp. 691-701
-
-
Moon, R.T.1
Kohn, A.D.2
De Ferrari, G.V.3
Kaykas, A.4
-
6
-
-
2442694379
-
Inhibition of Wnt-1 signaling induces apoptosis in beta-catenin-deficient mesothelioma cells
-
You, L., He, B., Uematsu, K. et al. Inhibition of Wnt-1 signaling induces apoptosis in beta-catenin-deficient mesothelioma cells. Cancer Res 2004, 64: 3474-8.
-
(2004)
Cancer Res
, vol.64
, pp. 3474-3478
-
-
You, L.1
He, B.2
Uematsu, K.3
-
7
-
-
0032483439
-
Identification of c-MYC as a target of the APC pathway
-
He, T.C., Sparks, A.B., Rago, C. et al. Identification of c-MYC as a target of the APC pathway. Science 1998, 281: 1509-12.
-
(1998)
Science
, vol.281
, pp. 1509-1512
-
-
He, T.C.1
Sparks, A.B.2
Rago, C.3
-
8
-
-
0041695485
-
A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling
-
Veeman, M.T., Axelrod, J.D., and Moon, R.T. A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling. Dev Cell 2003, 5: 367-77.
-
(2003)
Dev Cell
, vol.5
, pp. 367-377
-
-
Veeman, M.T.1
Axelrod, J.D.2
Moon, R.T.3
-
9
-
-
0026060707
-
A new nomenclature for int-1 and related genes: The Wnt gene family
-
Nusse, R., Brown, A., Papkoff, J. et al. A new nomenclature for int-1 and related genes: the Wnt gene family. Cell 1991, 64: 231.
-
(1991)
Cell
, vol.64
, pp. 231
-
-
Nusse, R.1
Brown, A.2
Papkoff, J.3
-
10
-
-
0023653232
-
The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless
-
Rijsewijk, F., Schuermann, M., Wagenaar, E., Parren, P., Weigel, D., and Nusse, R. The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless. Cell 1987, 50: 649-57.
-
(1987)
Cell
, vol.50
, pp. 649-657
-
-
Rijsewijk, F.1
Schuermann, M.2
Wagenaar, E.3
Parren, P.4
Weigel, D.5
Nusse, R.6
-
11
-
-
0021744029
-
Structure and nucleotide sequence of the putative mammary oncogene int-1; proviral insertions leave the protein-encoding domain intact
-
van Ooyen, A. and Nusse, R. Structure and nucleotide sequence of the putative mammary oncogene int-1; proviral insertions leave the protein-encoding domain intact. Cell 1984, 39: 233-40.
-
(1984)
Cell
, vol.39
, pp. 233-240
-
-
Van Ooyen, A.1
Nusse, R.2
-
12
-
-
0022157944
-
The nucleotide sequence of the human int-1 mammary oncogene: Evolutionary conservation of coding and non-coding sequences
-
van Ooyen, A., Kwee, V., and Nusse, R. The nucleotide sequence of the human int-1 mammary oncogene: evolutionary conservation of coding and non-coding sequences. EMBO J 1985, 4: 2905-9.
-
(1985)
EMBO J
, vol.4
, pp. 2905-2909
-
-
Van Ooyen, A.1
Kwee, V.2
Nusse, R.3
-
13
-
-
0022407950
-
Nucleotide sequence and expression in vitro of cDNA derived from mRNA of int-1, a provirally activated mouse mammary oncogene
-
Fung, Y.K., Shackleford, G.M., Brown. A.M., Sanders, G.S., and Varmus, H.E. Nucleotide sequence and expression in vitro of cDNA derived from mRNA of int-1, a provirally activated mouse mammary oncogene. Mol Cell Biol 1985, 5: 3337-44.
-
(1985)
Mol Cell Biol
, vol.5
, pp. 3337-3344
-
-
Fung, Y.K.1
Shackleford, G.M.2
Brown, A.M.3
Sanders, G.S.4
Varmus, H.E.5
-
14
-
-
0023448301
-
Identification of protein products encoded by the proto-oncogene int-1
-
Brown, A.M., Papkoff, J., Fung, Y.K., Shackleford, G.M., and Varmus, H.E. Identification of protein products encoded by the proto-oncogene int-1. Mol Cell Biol 1987, 7: 3971-7.
-
(1987)
Mol Cell Biol
, vol.7
, pp. 3971-3977
-
-
Brown, A.M.1
Papkoff, J.2
Fung, Y.K.3
Shackleford, G.M.4
Varmus, H.E.5
-
15
-
-
4043154959
-
Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine
-
Zhai, L., Chaturvedi, D., and Cumberledge, S. Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine. J Biol Chem 2004, 279: 33220-7.
-
(2004)
J Biol Chem
, vol.279
, pp. 33220-33227
-
-
Zhai, L.1
Chaturvedi, D.2
Cumberledge, S.3
-
16
-
-
0027359774
-
Activity of Wnt-1 as a transmembrane protein
-
Parkin, N.T., Kitajewski, J., and Varmus, H.E. Activity of Wnt-1 as a transmembrane protein. Genes Dev 1993, 7: 2181-93.
-
(1993)
Genes Dev
, vol.7
, pp. 2181-2193
-
-
Parkin, N.T.1
Kitajewski, J.2
Varmus, H.E.3
-
17
-
-
0026565374
-
The mouse Wnt-1 gene can act via a paracrine mechanism in transformation of mammary epithelial cells
-
Jue, S.F., Bradley, R.S., Rudnicki, J.A., Varmus, H.E., and Brown, A.M. The mouse Wnt-1 gene can act via a paracrine mechanism in transformation of mammary epithelial cells. Mol Cell Biol 1992, 12: 321-8.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 321-328
-
-
Jue, S.F.1
Bradley, R.S.2
Rudnicki, J.A.3
Varmus, H.E.4
Brown, A.M.5
-
18
-
-
0025188130
-
The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain
-
McMahon, A.P. and Bradley, A. The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain. Cell 1990, 62: 1073-85.
-
(1990)
Cell
, vol.62
, pp. 1073-1085
-
-
McMahon, A.P.1
Bradley, A.2
-
19
-
-
0025074908
-
Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development
-
Thomas, K.R. and Capecchi, M.R. Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development. Nature 1990, 346: 847-50.
-
(1990)
Nature
, vol.346
, pp. 847-850
-
-
Thomas, K.R.1
Capecchi, M.R.2
-
20
-
-
0025696476
-
Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development
-
Gavin, B.J., McMahon, J.A., and McMahon, A.P. Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development. Genes Dev, 4: 2319-2332, 1990.
-
(1990)
Genes Dev
, vol.4
, pp. 2319-2332
-
-
Gavin, B.J.1
McMahon, J.A.2
McMahon, A.P.3
-
21
-
-
0023623377
-
Expression of the proto-oncogene int-1 is restricted to postmeiotic male germ cells and the neural tube of mid-gestational embryos
-
Shackleford, G.M. and Varmus, H.E. Expression of the proto-oncogene int-1 is restricted to postmeiotic male germ cells and the neural tube of mid-gestational embryos. Cell, 50: 89-95, 1987.
-
(1987)
Cell
, vol.50
, pp. 89-95
-
-
Shackleford, G.M.1
Varmus, H.E.2
-
22
-
-
0022993326
-
A retrovirus vector expressing the putative mammary oncogene int-1 causes partial transformation of a mammary epithelial cell line
-
Brown, A.M., Wildin, R.S., Prendergast, T.J., and Varmus, H.E. A retrovirus vector expressing the putative mammary oncogene int-1 causes partial transformation of a mammary epithelial cell line. Cell 1986, 46: 1001-9.
-
(1986)
Cell
, vol.46
, pp. 1001-1009
-
-
Brown, A.M.1
Wildin, R.S.2
Prendergast, T.J.3
Varmus, H.E.4
-
23
-
-
0031456662
-
Transformation by Wnt family proteins correlates with regulation of beta-catenin
-
Shimizu, H., Julius, M.A., Giarre, M., Zheng, Z., Brown, A.M., and Kitajewski, J. Transformation by Wnt family proteins correlates with regulation of beta-catenin. Cell Growth Differ 1997, 8: 1349-58.
-
(1997)
Cell Growth Differ
, vol.8
, pp. 1349-1358
-
-
Shimizu, H.1
Julius, M.A.2
Giarre, M.3
Zheng, Z.4
Brown, A.M.5
Kitajewski, J.6
-
24
-
-
0037442760
-
Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis
-
Gunther, E.J., Moody, S.E., Belka, G.K. et al. Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis. Genes Dev 2003, 17: 488-501.
-
(2003)
Genes Dev
, vol.17
, pp. 488-501
-
-
Gunther, E.J.1
Moody, S.E.2
Belka, G.K.3
-
25
-
-
18344377028
-
Blockade of Wnt-1 signaling induces apoptosis in human colorectal cancer cells containing downstream mutations
-
He, B., Reguart, N., You, L. et al. Blockade of Wnt-1 signaling induces apoptosis in human colorectal cancer cells containing downstream mutations. Oncogene 2005, 24: 3054-8.
-
(2005)
Oncogene
, vol.24
, pp. 3054-3058
-
-
He, B.1
Reguart, N.2
You, L.3
-
26
-
-
16444374026
-
Constitutive activation of the Wnt/beta-catenin signalling pathway in acute myeloid leukaemia
-
Simon, M., Grandage, V.L., Linen, D.C., and Khwaja, A. Constitutive activation of the Wnt/beta-catenin signalling pathway in acute myeloid leukaemia. Oncogene 2005, 24: 2410-20.
-
(2005)
Oncogene
, vol.24
, pp. 2410-2420
-
-
Simon, M.1
Grandage, V.L.2
Linen, D.C.3
Khwaja, A.4
-
27
-
-
0036144406
-
Wnt-1 but not epidermal growth factor induces beta-catenin/T-cell factor-dependent transcription in esophageal cancer cells
-
Mizushima, T., Nakagawa, H., Kamberov, Y.G., Wilder, E.L., Klein, P.S., and Rustgi, A.K. Wnt-1 but not epidermal growth factor induces beta-catenin/T-cell factor-dependent transcription in esophageal cancer cells. Cancer Res 2002, 62: 277-82.
-
(2002)
Cancer Res
, vol.62
, pp. 277-282
-
-
Mizushima, T.1
Nakagawa, H.2
Kamberov, Y.G.3
Wilder, E.L.4
Klein, P.S.5
Rustgi, A.K.6
-
28
-
-
24744460574
-
Effect of WNT-1 on beta-catenin expression and its relation to Ki-67 and tumor differentiation in oral squamous cell carcinoma
-
Zhang, W.M., Lo Muzio, L., Rubini, C., and Van, G. Effect of WNT-1 on beta-catenin expression and its relation to Ki-67 and tumor differentiation in oral squamous cell carcinoma. Oncol Rep 2005, 13: 1095-9.
-
(2005)
Oncol Rep
, vol.13
, pp. 1095-1099
-
-
Zhang, W.M.1
Lo Muzio, L.2
Rubini, C.3
Van, G.4
-
29
-
-
4444326415
-
Up-regulation of Wnt-1 and beta-catenin production in patients with advanced metastatic prostate carcinoma: Potential pathogenetic and prognostic implications
-
Chen, G. Shukeir, N., Potti, A., Sircar, K., Aprikian, A., Goltzman, D., and Rabbani, S.A. Up-regulation of Wnt-1 and beta-catenin production in patients with advanced metastatic prostate carcinoma: potential pathogenetic and prognostic implications. Cancer 2004, 101: 1345-56.
-
(2004)
Cancer
, vol.101
, pp. 1345-1356
-
-
Chen, G.1
Shukeir, N.2
Potti, A.3
Sircar, K.4
Aprikian, A.5
Goltzman, D.6
Rabbani, S.A.7
-
30
-
-
2542546650
-
Hepatitis B virus X protein is essential for the activation of Wnt/beta-catenin signaling in hepatoma cells
-
Cha, M.Y., Kim, C.M., Park, Y.M., and Ryu, W. S. Hepatitis B virus X protein is essential for the activation of Wnt/beta-catenin signaling in hepatoma cells. Hepatology 2004, 39: 1683-93.
-
(2004)
Hepatology
, vol.39
, pp. 1683-1693
-
-
Cha, M.Y.1
Kim, C.M.2
Park, Y.M.3
Ryu, W.S.4
-
31
-
-
17844372967
-
Hepatitis C virus core protein stimulates hepatocyte growth: Correlation with upregulation of wnt-1 expression
-
Fukutomi, T., Zhou, Y., Kawai, S., Eguchi, H., Wands, J.R., and Li, J. Hepatitis C virus core protein stimulates hepatocyte growth: correlation with upregulation of wnt-1 expression. Hepatology 2005, 41: 1096-105.
-
(2005)
Hepatology
, vol.41
, pp. 1096-1105
-
-
Fukutomi, T.1
Zhou, Y.2
Kawai, S.3
Eguchi, H.4
Wands, J.R.5
Li, J.6
-
32
-
-
0037179894
-
Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas
-
Rhee, C.S., Sen, M., Lu, D. et al. Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas. Oncogene 2002, 21: 6598-605.
-
(2002)
Oncogene
, vol.21
, pp. 6598-6605
-
-
Rhee, C.S.1
Sen, M.2
Lu, D.3
-
33
-
-
1642341682
-
A monoclonal antibody against Wnt-1 induces apoptosis in human cancer cells
-
He, B., You, L., Uematsu, K. et al. A monoclonal antibody against Wnt-1 induces apoptosis in human cancer cells. Neoplasia 2004, 6: 7-14.
-
(2004)
Neoplasia
, vol.6
, pp. 7-14
-
-
He, B.1
You, L.2
Uematsu, K.3
-
34
-
-
26844569797
-
Efficacy of Wnt-1 monoclonal antibody in sarcoma cells
-
Mikami, I., You, L., He, B. et al. Efficacy of Wnt-1 monoclonal antibody in sarcoma cells. BMC Cancer 2005, 5: 53.
-
(2005)
BMC Cancer
, vol.5
, pp. 53
-
-
Mikami, I.1
You, L.2
He, B.3
-
35
-
-
12144291274
-
Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer
-
Suzuki, H., Watkins, D.N., Jair, K.W. et al. Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer. Nat Genet 2004, 36: 417-22.
-
(2004)
Nat Genet
, vol.36
, pp. 417-422
-
-
Suzuki, H.1
Watkins, D.N.2
Jair, K.W.3
-
36
-
-
7944230668
-
An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells
-
Bafico, A., Liu, G., Goldin, L., Harris, V., and Aaronson, S.A. An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells. Cancer Cell 2004, 6: 497-506.
-
(2004)
Cancer Cell
, vol.6
, pp. 497-506
-
-
Bafico, A.1
Liu, G.2
Goldin, L.3
Harris, V.4
Aaronson, S.A.5
-
37
-
-
20444397431
-
Identification of bronchioalveolar stem cells in normal lung and lung cancer
-
Kim, C.F., Jackson, E.L., Woolfenden, A.E. et al. Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell 2005, 121: 823-35.
-
(2005)
Cell
, vol.121
, pp. 823-835
-
-
Kim, C.F.1
Jackson, E.L.2
Woolfenden, A.E.3
-
38
-
-
0043092191
-
Wnt pathway activation in mesothelioma: Evidence of Dishevelled overexpression and transcriptional activity of beta-catenin
-
Uematsu, K., Kanazawa, S., You, L. et al. Wnt pathway activation in mesothelioma: evidence of Dishevelled overexpression and transcriptional activity of beta-catenin. Cancer Res 2003, 63: 4547-51.
-
(2003)
Cancer Res
, vol.63
, pp. 4547-4551
-
-
Uematsu, K.1
Kanazawa, S.2
You, L.3
-
39
-
-
0242551656
-
Activation of the Wnt pathway in non small cell lung cancer: Evidence of dishevelled overexpression
-
Uematsu, K., He, B., You, L., Xu, Z., McCormick, F., and Jablons, D.M. Activation of the Wnt pathway in non small cell lung cancer: evidence of dishevelled overexpression. Oncogene 2003, 22: 7218-21.
-
(2003)
Oncogene
, vol.22
, pp. 7218-7221
-
-
Uematsu, K.1
He, B.2
You, L.3
Xu, Z.4
McCormick, F.5
Jablons, D.M.6
-
40
-
-
0031436939
-
Induction of a beta-catenin-LEF-1 complex by wnt-1 and transforming mutants of beta-catenin
-
Porfiri, E., Rubinfeld, B., Albert, I., Hovanes, K., Waterman, M., and Polakis, P. Induction of a beta-catenin-LEF-1 complex by wnt-1 and transforming mutants of beta-catenin. Oncogene 1997, 15: 2833-9.
-
(1997)
Oncogene
, vol.15
, pp. 2833-2839
-
-
Porfiri, E.1
Rubinfeld, B.2
Albert, I.3
Hovanes, K.4
Waterman, M.5
Polakis, P.6
-
41
-
-
0037193466
-
Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis
-
You, Z., Saims, D., Chen, S. et al. Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis. J Cell Biol 2002, 157: 429-40.
-
(2002)
J Cell Biol
, vol.157
, pp. 429-440
-
-
You, Z.1
Saims, D.2
Chen, S.3
-
42
-
-
0033119801
-
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
-
Tetsu, O. and McCormick, F. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999, 398: 422-6.
-
(1999)
Nature
, vol.398
, pp. 422-426
-
-
Tetsu, O.1
McCormick, F.2
-
43
-
-
85047699343
-
Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA
-
Shou, J., Ali-Osman, F., Multani, A.S., Pathak, S., Fedi, P., and Srivenugopal, K.S. Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA. Oncogene 2002, 21: 878-89.
-
(2002)
Oncogene
, vol.21
, pp. 878-889
-
-
Shou, J.1
Ali-Osman, F.2
Multani, A.S.3
Pathak, S.4
Fedi, P.5
Srivenugopal, K.S.6
-
44
-
-
4644302254
-
Dickkopf-1 antagonizes Wnt signaling independent of beta-catenin in human mesothelioma
-
Lee, A.Y., He, B., You, L. et al. Dickkopf-1 antagonizes Wnt signaling independent of beta-catenin in human mesothelioma. Biochem Biophys Res Commun 2004, 323: 1246-50.
-
(2004)
Biochem Biophys Res Commun
, vol.323
, pp. 1246-1250
-
-
Lee, A.Y.1
He, B.2
You, L.3
|