Accelerated growth of intestinal tumours after radiation exposure in Mlh1-knockout mice: Evaluation of the late effect of radiation on a mouse model of HNPCC

International Journal of Experimental Pathology

Volumn 87, Issue 2, 2006, Pages 89-99

  Tokairin, Yutaka ^a,b   Kakinuma, Shizuko ^b   Arai, Masami ^c   Nishimura, Mayumi ^b   Okamoto, Mieko ^d   Ito, Eisaku ^a   Akashi, Makoto ^b   Miki, Yoshio ^a   Kawano, Tatsuyuki ^a   Iwai, Takehisa ^a   Shimada, Yoshiya ^b  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^c CANCER INSTITUTE HOSPITAL   (Japan)

^d TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

Colorectal carcinogenesis; HNPCC; Mismatch repair; Mlh1; Radiation

Indexed keywords

PROTEIN MLH1; PROTEIN P53; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CANCER SUSCEPTIBILITY; CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; DIGESTIVE SYSTEM CANCER; GASTROINTESTINAL CARCINOMA; GENE MUTATION; HISTOPATHOLOGY; IONIZING RADIATION; KNOCKOUT MOUSE; MOUSE; MUCINOUS CARCINOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION EXPOSURE; THYMUS LYMPHOMA;

ADENOCARCINOMA; ANIMALS; BASE PAIR MISMATCH; BETA CATENIN; CARRIER PROTEINS; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; GASTROINTESTINAL NEOPLASMS; GENES, NEOPLASM; IMMUNOHISTOCHEMISTRY; LYMPHOMA; MICE; MICE, KNOCKOUT; MUTATION; NEOPLASM PROTEINS; NUCLEAR PROTEINS; RADIOTHERAPY; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; THYMUS NEOPLASMS; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA2; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33645350398     PISSN: 09599673     EISSN: 13652613     Source Type: Journal    
DOI: 10.1111/j.0959-9673.2006.00464.x     Document Type: Article

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