메뉴 건너뛰기




Volumn 114, Issue 2, 1998, Pages 268-274

Proapoptotic gene BAX is frequently mutated in hereditary nonpolyposis colorectal cancers but not in adenomas

Author keywords

[No Author keywords available]

Indexed keywords

DNA; PROTEIN BAX; PROTEIN P53;

EID: 0031940209     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(98)70477-9     Document Type: Article
Times cited : (97)

References (33)
  • 1
    • 0029833872 scopus 로고    scopus 로고
    • Hereditary nonpolyposis colorectal cancer (Lynch syndrome)
    • HT Lynch T. Smyrk Hereditary nonpolyposis colorectal cancer (Lynch syndrome) Cancer 78 1996 1149 1167
    • (1996) Cancer , vol.78 , pp. 1149-1167
    • Lynch, HT1    Smyrk, T.2
  • 2
    • 0030592517 scopus 로고    scopus 로고
    • Lessons from hereditary colorectal cancer
    • KW Kinzler B. Vogelstein Lessons from hereditary colorectal cancer Cell 87 1996 159 170
    • (1996) Cell , vol.87 , pp. 159-170
    • Kinzler, KW1    Vogelstein, B.2
  • 3
    • 0030604542 scopus 로고    scopus 로고
    • TGFβ signaling: receptors, transducers, and Mad proteins
    • J. Massagué TGFβ signaling: receptors, transducers, and Mad proteins Cell 85 1996 947 950
    • (1996) Cell , vol.85 , pp. 947-950
    • Massagué, J.1
  • 4
    • 0029868841 scopus 로고    scopus 로고
    • Negative regulation of cell growth by TGFβ
    • K. Polyak Negative regulation of cell growth by TGFβ Biochim Biophys Acta 1242 1996 185 199
    • (1996) Biochim Biophys Acta , vol.1242 , pp. 185-199
    • Polyak, K.1
  • 5
    • 0028556486 scopus 로고
    • Genetic changes in the transforming growth factor β (TGF-β) type II receptor gene in human gastric cancer cells: Correlation with sensitivity to growth inhibition by TGF-β
    • K Park S-J Kim Y-J Bang J-G Park NK Kim AB Roberts MB. Sporn Genetic changes in the transforming growth factor β (TGF-β) type II receptor gene in human gastric cancer cells: Correlation with sensitivity to growth inhibition by TGF-β Proc Natl Acad Sci USA 91 1994 8772 8776
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8772-8776
    • Park, K1    Kim, S-J2    Bang, Y-J3    Park, J-G4    Kim, NK5    Roberts, AB6    Sporn, MB.7
  • 6
    • 0029114477 scopus 로고
    • Missense mutations of the transforming growth factor β type II receptor in human head and neck squamous carcinoma cells
    • L Garrigue-Antar T Munõz-Antonia SJ Antonia J Gesmonde VF Velluci M. Reiss Missense mutations of the transforming growth factor β type II receptor in human head and neck squamous carcinoma cells Cancer Res 55 1995 3982 3987
    • (1995) Cancer Res , vol.55 , pp. 3982-3987
    • Garrigue-Antar, L1    Munõz-Antonia, T2    Antonia, SJ3    Gesmonde, J4    Velluci, VF5    Reiss, M.6
  • 8
    • 0028826107 scopus 로고
    • Mutations of the transforming growth factor-β type II receptor gene and genomic instability in hereditary nonpolyposis colorectal cancer
    • S-L Lu Y Akiyama H Nagasaki K Saitoh Y. Yuasa Mutations of the transforming growth factor-β type II receptor gene and genomic instability in hereditary nonpolyposis colorectal cancer Biochem Biophys Res Commun 216 1995 452 457
    • (1995) Biochem Biophys Res Commun , vol.216 , pp. 452-457
    • Lu, S-L1    Akiyama, Y2    Nagasaki, H3    Saitoh, K4    Yuasa, Y.5
  • 9
    • 0028785603 scopus 로고
    • Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer
    • R Parsons LL Myeroff B Liu JKV Willson SD Markowitz KW Kinzler B. Vogelstein Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer Cancer Res 55 1995 5548 5550
    • (1995) Cancer Res , vol.55 , pp. 5548-5550
    • Parsons, R1    Myeroff, LL2    Liu, B3    Willson, JKV4    Markowitz, SD5    Kinzler, KW6    Vogelstein, B.7
  • 10
    • 0031014282 scopus 로고    scopus 로고
    • Transforming growth factor β type II receptor gene mutations in adenomas from hereditary nonpolyposis colorectal cancer
    • Y Akiyama R Iwanaga K Saitoh K Shiba K Ushio E Ikeda T Iwama T Nomizu Y. Yuasa Transforming growth factor β type II receptor gene mutations in adenomas from hereditary nonpolyposis colorectal cancer Gastroenterology 112 1997 33 39
    • (1997) Gastroenterology , vol.112 , pp. 33-39
    • Akiyama, Y1    Iwanaga, R2    Saitoh, K3    Shiba, K4    Ushio, K5    Ikeda, E6    Iwama, T7    Nomizu, T8    Yuasa, Y.9
  • 11
    • 0027285475 scopus 로고
    • Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
    • Y Ionov MA Peinado S Malkhosyan D Shibata M. Perucho Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis Nature 363 1993 558 561
    • (1993) Nature , vol.363 , pp. 558-561
    • Ionov, Y1    Peinado, MA2    Malkhosyan, S3    Shibata, D4    Perucho, M.5
  • 14
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death
    • ZN Oltvai CL Milliman SJ. Korsmeyer Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death Cell 74 1993 609 619
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, ZN1    Milliman, CL2    Korsmeyer, SJ.3
  • 15
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • T Miyashita JC. Reed Tumor suppressor p53 is a direct transcriptional activator of the human bax gene Cell 80 1995 293 299
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T1    Reed, JC.2
  • 16
    • 0031018674 scopus 로고    scopus 로고
    • Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype
    • N Rampino H Yamamoto Y Ionov Y Li H Sawai JC Reed M. Perucho Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype Science 275 1997 967 969
    • (1997) Science , vol.275 , pp. 967-969
    • Rampino, N1    Yamamoto, H2    Ionov, Y3    Li, Y4    Sawai, H5    Reed, JC6    Perucho, M.7
  • 18
    • 0025848680 scopus 로고
    • The international collaborative group on hereditary non-polyposis colorectal cancer (ICG-HNPCC)
    • HFA Vasen J-P Mecklin P Meera Khan HT. Lynch The international collaborative group on hereditary non-polyposis colorectal cancer (ICG-HNPCC) Dis Colon Rectum 34 1991 424 425
    • (1991) Dis Colon Rectum , vol.34 , pp. 424-425
    • Vasen, HFA1    Mecklin, J-P2    Meera Khan, P3    Lynch, HT.4
  • 20
    • 0017148259 scopus 로고
    • A general method for isolation of high molecular weight DNA from eukaryotes
    • N Blin DW. Stafford A general method for isolation of high molecular weight DNA from eukaryotes Nucleic Acids Res 3 1976 2303 2308
    • (1976) Nucleic Acids Res , vol.3 , pp. 2303-2308
    • Blin, N1    Stafford, DW.2
  • 21
    • 0022253232 scopus 로고
    • Purification of DNA from formaldehyde fixed and paraffin embedded human tissue
    • SE Goelz SR Hamilton B. Vogelstein Purification of DNA from formaldehyde fixed and paraffin embedded human tissue Biochem Biophys Res Commun 130 1985 118 126
    • (1985) Biochem Biophys Res Commun , vol.130 , pp. 118-126
    • Goelz, SE1    Hamilton, SR2    Vogelstein, B.3
  • 23
    • 0027203926 scopus 로고
    • Optimization of nonradioisotopic single strand conformation polymorphism analysis with a conventional minislab gel electrophoresis apparatus
    • M Oto S Miyake Y. Yuasa Optimization of nonradioisotopic single strand conformation polymorphism analysis with a conventional minislab gel electrophoresis apparatus Anal Biochem 213 1993 19 22
    • (1993) Anal Biochem , vol.213 , pp. 19-22
    • Oto, M1    Miyake, S2    Yuasa, Y.3
  • 25
    • 0028362325 scopus 로고
    • Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation
    • D Shibata MA Peinado Y Ionov S Malkhosyan M. Perucho Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation Nat Genet 6 1994 273 281
    • (1994) Nat Genet , vol.6 , pp. 273-281
    • Shibata, D1    Peinado, MA2    Ionov, Y3    Malkhosyan, S4    Perucho, M.5
  • 28
    • 0031038137 scopus 로고    scopus 로고
    • Bax suppresses tumorigenesis and stimulates apoptosis in vivo
    • C Yin CM Knudson SJ Korsmeyer T. Van Dyke Bax suppresses tumorigenesis and stimulates apoptosis in vivo Nature 385 1997 637 640
    • (1997) Nature , vol.385 , pp. 637-640
    • Yin, C1    Knudson, CM2    Korsmeyer, SJ3    Van Dyke, T.4
  • 29
    • 0031577279 scopus 로고    scopus 로고
    • Frequent somatic mutations of hMSH3 with reference to microsatellite instability in hereditary nonpolyposis colorectal cancers
    • Y Akiyama N Tsubouchi Y. Yuasa Frequent somatic mutations of hMSH3 with reference to microsatellite instability in hereditary nonpolyposis colorectal cancers Biochem Biophys Res Commun 236 1997 248 252
    • (1997) Biochem Biophys Res Commun , vol.236 , pp. 248-252
    • Akiyama, Y1    Tsubouchi, N2    Yuasa, Y.3
  • 30
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • AJ. Levine p53, the cellular gatekeeper for growth and division Cell 88 1997 323 331
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, AJ.1
  • 31
    • 0030892234 scopus 로고    scopus 로고
    • Apoptosis by death factor
    • S. Nagata Apoptosis by death factor Cell 88 1997 355 365
    • (1997) Cell , vol.88 , pp. 355-365
    • Nagata, S.1
  • 33
    • 0000277795 scopus 로고
    • General rules for clinical and pathological studies on cancer of the colon, rectum and anus
    • Japanese Research Society for Cancer of the Colon and Rectum General rules for clinical and pathological studies on cancer of the colon, rectum and anus Jpn J Surg 13 1983 557 598
    • (1983) Jpn J Surg , vol.13 , pp. 557-598
    • Japanese Research Society for Cancer of the Colon and Rectum1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.