Microsatellite instability in sporadic carcinomas of the proximal colon: Association with diploid DNA content, negative protein expression of p53, and distinct histomorphologic features

Surgery

Volumn 123, Issue 1, 1998, Pages 13-18

  Forster, S ^a   Sattler, H P ^a   Hack, M ^a   Romanakis, K ^a   Rohde, V ^a   Seitz, G ^a   Wullich, B ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MICROSATELLITE DNA;

ADENOCARCINOMA; ARTICLE; ASCENDING COLON; CANCER GRADING; CANCER STAGING; COLON CARCINOMA; CRYOPRESERVATION; DNA CONTENT; DNA DETERMINATION; FLOW CYTOMETRY; GENOTYPE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MORPHOMETRICS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0031907144     PISSN: 00396060     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-6060(98)70223-5     Document Type: Article

References (18)

1. ER Fearon B Vogelstein A genetic model for colorectal tumorigenesis Cell 61 1990 759 767
2. LA Aaltonen P Peltomäki FS Leach P Sistonen L Pylkkänen JP Mecklin Clues to the pathogenesis of familial colorectal cancer Science 260 1993 812 815
3. Y Ionov MA Peinado S Malkhosyan D Shibata M Perucho Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis Nature 363 1993 558 561
4. RA Lothe P Peltomäki GI Meling AL Aaltonen M Nyström-Lahti L Pylkkänen Genomic instability in colorectal cancer: relationship to clinicopathological variables and family history Cancer Res 53 1993 5849 5852
5. SN Thibodeau G Bren D Schaid Microsatellite instability in cancer of the proximal colon Science 260 1993 816 819
6. G Moslein DJ Tester NM Lindor R Honchel JM Cunningham AJ French Microsatellite instability and mutation analysis of hMSH2 and hMLH1 in patients with sporadic, familial and hereditary colorectal cancer Hum Mol Genet 5 1996 1245 1252
7. H Kim J Jen B Vogelstein SR Hamilton Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences Am J Pathol 145 1994 148 156
8. T Bocker J Schlegel F Kullmann G Stumm H Zirngibl JT Epplen Genomic instability in colorectal carcinomas: comparison of different evaluation methods and their tumorbiological significance J Pathol 178 1996 221 226
9. H Muta M Noguchi M Perucho K Ushio K Sugihara A Ochiai Clinical implications of microsatellite instability in colorectal cancers Cancer 77 1996 265 270
10. J Weissenbach G Gyapay C Dib A Vignal J Morissette P Millasseau A second-generation linkage map of the human genome Nature 359 1992 794 801
11. RE Straub MC Speer Y Luo K Rojas J Overhauser J Ott A microsatellite genetic linkage map of human chromosome 18 Genomics 15 1993 48 56
12. J Schlegel T Bocker H Zirngibl F Hofstädter J Rüschoff Detection of microsatellite instability in human colorectal carcinomas using a non-radioactive PCR-based screening technique Virch Arch 426 1995 223 227
13. IO Baas JW Mulder GJ Offerhaus B Vogelstein SR Hamilton An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms J Pathol 172 1994 5 12
14. B Woolf The long likelihood ratio test (the G test): methods and tables for tests of heterogeneity in contingency tables Ann Hum Genet 21 1957 397 409
15. JA Bufill Colorectal cancer: evidence for distinct genetic categories based on proximal or distal tumor location Ann Intern Med 113 1990 779 788
16. DP Lane P53, guardian of the genome Nature 358 1992 15 16
17. S Aebi B Kurdi-Haidar R Gordon B Cenni H Zheng D Fink Loss of DNA mismatch repair in acquired resistance to cisplatin Cancer Res 56 1996 3087 3090
18. M Gariboldi M Gupta CR Boland Y Pommier Increased sensitivity to camptothecin in human colon carcinoma cell lines with mismatch repair deficiency [abstract] Proc Am Assoc Cancer Res 37 1996 431