메뉴 건너뛰기




Volumn 10, Issue 3, 2005, Pages 125-131

Biology of nuclear transcription factor NF-κB;Właściwości biologiczne czynnika transkrypcji ja̧drowej NF-κB

Author keywords

Activation pathways; Biological role; IKK; I B; NF B

Indexed keywords

HETERODIMER; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P50; TRANSCRIPTION FACTOR RELA;

EID: 33645341961     PISSN: 14273101     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (10)

References (69)
  • 1
    • 0442307969 scopus 로고    scopus 로고
    • IκB kinases: Key regulators of the NF-κB pathway
    • Yamamoto Y, Gaynor RB. IκB kinases: key regulators of the NF-κB pathway. Trends Biochem Sci 2004; 29: 72-79.
    • (2004) Trends Biochem Sci , vol.29 , pp. 72-79
    • Yamamoto, Y.1    Gaynor, R.B.2
  • 2
    • 3042563555 scopus 로고    scopus 로고
    • Genetic dissection of antigen receptor induced - NF-κB activation
    • Li ZW, Rickert RC, Karin M. Genetic dissection of antigen receptor induced - NF-κB activation. Mol Immunol 2004; 41: 701-714.
    • (2004) Mol Immunol , vol.41 , pp. 701-714
    • Li, Z.W.1    Rickert, R.C.2    Karin, M.3
  • 3
    • 0043092575 scopus 로고    scopus 로고
    • Distinctions between c-Re1 and other NF-κB proteins in immunity and disease
    • Liou HCh, Hsia CY. Distinctions between c-Re1 and other NF-κB proteins in immunity and disease. BioEssays 2003; 25: 767-780.
    • (2003) BioEssays , vol.25 , pp. 767-780
    • Liou, H.Ch.1    Hsia, C.Y.2
  • 4
    • 0742287249 scopus 로고    scopus 로고
    • From antigen to activation: Specific signal transduction pathways linking antigen receptors to NF-κB
    • Ruland J, Mak TW. From antigen to activation: specific signal transduction pathways linking antigen receptors to NF-κB. Semin Immunol 2003; 15: 177-183.
    • (2003) Semin Immunol , vol.15 , pp. 177-183
    • Ruland, J.1    Mak, T.W.2
  • 5
    • 17544365995 scopus 로고    scopus 로고
    • The IκB/NF-κB system: A key determinant of mucosal inflammation and protection
    • Jobin Ch, Sartor RB. The IκB/NF-κB system: a key determinant of mucosal inflammation and protection. Am J Physiol Cell Physiol 2000; 278: C451-C462.
    • (2000) Am J Physiol Cell Physiol , vol.278
    • Jobin, Ch.1    Sartor, R.B.2
  • 6
    • 0031897632 scopus 로고    scopus 로고
    • NF-κB and Rel proteins: Evolutionarily conserved mediators of immune responses
    • Ghosh S, May MJ, Kopp EB. NF-κB and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol 1998; 16: 225-260.
    • (1998) Annu Rev Immunol , vol.16 , pp. 225-260
    • Ghosh, S.1    May, M.J.2    Kopp, E.B.3
  • 7
    • 0022481133 scopus 로고
    • Multiple nuclear factors interact with the immunoglobulin enhancer sequences
    • Sen R, Baltimore D. Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell 1986; 46: 705-716.
    • (1986) Cell , vol.46 , pp. 705-716
    • Sen, R.1    Baltimore, D.2
  • 8
    • 1542285414 scopus 로고    scopus 로고
    • The NF-κB signaling pathway: Immune evasion and immunoregulation during toxoplasmosis
    • Shapira S, Harb OS, Caamano J i wsp. The NF-κB signaling pathway: immune evasion and immunoregulation during toxoplasmosis. Int J Parasitol 2004; 34: 393-400.
    • (2004) Int J Parasitol , vol.34 , pp. 393-400
    • Shapira, S.1    Harb, O.S.2    Caamano, J.3
  • 9
    • 16644386505 scopus 로고    scopus 로고
    • Czynnik transkrypcjny NF-κB - Nowa perspektywa w leczeniu nowotworów
    • Gruber BM. Czynnik transkrypcjny NF-κB - nowa perspektywa w leczeniu nowotworów. Post Biochem 2004; 50: 118-130.
    • (2004) Post Biochem , vol.50 , pp. 118-130
    • Gruber, B.M.1
  • 12
    • 0035174615 scopus 로고    scopus 로고
    • The transcription factor NF-κB and human disease
    • Baldwin AS. The transcription factor NF-κB and human disease. J Clin Invest 2001; 107: 3-6.
    • (2001) J Clin Invest , vol.107 , pp. 3-6
    • Baldwin, A.S.1
  • 13
    • 2342464085 scopus 로고    scopus 로고
    • The two NF-κB activation pathways and their role in innate and adaptive immunity
    • Bonizzi G, Karin M. The two NF-κB activation pathways and their role in innate and adaptive immunity. Trends Immunol 2004; 25: 280-288.
    • (2004) Trends Immunol , vol.25 , pp. 280-288
    • Bonizzi, G.1    Karin, M.2
  • 15
    • 0031906550 scopus 로고    scopus 로고
    • Signal transduction through NF-κB
    • May MJ, Ghosh S. Signal transduction through NF-κB. Rev Immunol Today 1998; 19: 80-88.
    • (1998) Rev Immunol Today , vol.19 , pp. 80-88
    • May, M.J.1    Ghosh, S.2
  • 16
    • 0031757934 scopus 로고    scopus 로고
    • Nuclear Factor kappa B: Important transcriptional factor and therapeutic target
    • Lee JI, Burckart GJ. Nuclear Factor kappa B: important transcriptional factor and therapeutic target. J Clin Pharmacol 1998; 38: 981-993.
    • (1998) J Clin Pharmacol , vol.38 , pp. 981-993
    • Lee, J.I.1    Burckart, G.J.2
  • 17
    • 0037290892 scopus 로고    scopus 로고
    • Drosophila immunity: Paths and patterns
    • Hultmark D. Drosophila immunity: paths and patterns. Curr Opin Immunol 2003; 15: 12-19.
    • (2003) Curr Opin Immunol , vol.15 , pp. 12-19
    • Hultmark, D.1
  • 18
  • 19
    • 0034287444 scopus 로고    scopus 로고
    • Drosophila IκB kinase complex required for relish cleavage and antibacterial immunity
    • Silverman N, Zhou R, Stoven S i wsp. Drosophila IκB kinase complex required for relish cleavage and antibacterial immunity. Genes Dev 2000; 14: 2461-2471.
    • (2000) Genes Dev , vol.14 , pp. 2461-2471
    • Silverman, N.1    Zhou, R.2    Stoven, S.3
  • 20
    • 0033118490 scopus 로고    scopus 로고
    • Toll receptor-mediated Drosophila immune response requires Dif, an NF-κB factor
    • Meng X, Khanuja BS, Ip YT. Toll receptor-mediated Drosophila immune response requires Dif, an NF-κB factor. Genes Dev 1998; 13: 792-797.
    • (1998) Genes Dev , vol.13 , pp. 792-797
    • Meng, X.1    Khanuja, B.S.2    Ip, Y.T.3
  • 21
    • 0029730738 scopus 로고    scopus 로고
    • A conserved signalling pathway: The Drosophila Toll-Dorsal pathway
    • Belvin MP, Anderson KV. A conserved signalling pathway: the Drosophila Toll-Dorsal pathway. Annu Rev Cell Biol 1996; 12: 393-416.
    • (1996) Annu Rev Cell Biol , vol.12 , pp. 393-416
    • Belvin, M.P.1    Anderson, K.V.2
  • 22
    • 0034283837 scopus 로고    scopus 로고
    • The Rel/NF-κB family: Friend or foe
    • Perkins ND. The Rel/NF-κB family: friend or foe. TIBS 2000; 25: 434-440.
    • (2000) TIBS , vol.25 , pp. 434-440
    • Perkins, N.D.1
  • 23
    • 0001228390 scopus 로고    scopus 로고
    • Missing pieces in the NF-κB puzzle
    • Gosh S, Karin M. Missing pieces in the NF-κB puzzle. Cell 2002; 109: 881-896.
    • (2002) Cell , vol.109 , pp. 881-896
    • Gosh, S.1    Karin, M.2
  • 24
    • 0034668171 scopus 로고    scopus 로고
    • Oxidative stress interference with the nuclear factor - κB activation pathways
    • Schoonbroodt S, Piete J. Oxidative stress interference with the Nuclear Factor - κB activation pathways. Biochem Pharmacol 2000; 60: 1075-1083.
    • (2000) Biochem Pharmacol , vol.60 , pp. 1075-1083
    • Schoonbroodt, S.1    Piete, J.2
  • 25
    • 0029874138 scopus 로고    scopus 로고
    • The NF-κ and IκB proteins: New discoveries and insights
    • Baldwin AS. The NF-κ and IκB proteins: new discoveries and insights. Annu Rev Immunol 1996; 14: 649-662.
    • (1996) Annu Rev Immunol , vol.14 , pp. 649-662
    • Baldwin, A.S.1
  • 26
    • 0033304494 scopus 로고    scopus 로고
    • Molecular control of immune/inflammatory responses: Interactions between Nuclear Factor - κB and steroid receptor-signaling pathway
    • McKay LI, Cidlowski JA. Molecular control of immune/inflammatory responses: interactions between Nuclear Factor - κB and steroid receptor-signaling pathway. Endocrinol Rev 1999; 20: 435-459.
    • (1999) Endocrinol Rev , vol.20 , pp. 435-459
    • McKay, L.I.1    Cidlowski, J.A.2
  • 27
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquination: The control of NF-κB activity
    • Karin M, Ben-Neriah Y. Phosphorylation meets ubiquination: the control of NF-κB activity. Annu Rev Immunol 2000; 18: 621-663.
    • (2000) Annu Rev Immunol , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 28
    • 0033607313 scopus 로고    scopus 로고
    • The NF-κB activation pathway: A paradigm in information transfer from membrane to nucleus
    • Rothwarf DM, Karin M. The NF-κB activation pathway: a paradigm in information transfer from membrane to nucleus. Science Stke 1999; 1-16, www.stke.org.
    • (1999) Science Stke , pp. 1-16
    • Rothwarf, D.M.1    Karin, M.2
  • 29
    • 0031183766 scopus 로고    scopus 로고
    • The role of Nuclear Factor-κB in cytokine gene regulation
    • Blackwell TS, Christman JW. The role of Nuclear Factor-κB in cytokine gene regulation. Am J Respir Cell Mol Biol 1997; 17: 3-9.
    • (1997) Am J Respir Cell Mol Biol , vol.17 , pp. 3-9
    • Blackwell, T.S.1    Christman, J.W.2
  • 30
    • 0031840980 scopus 로고    scopus 로고
    • Role of transcription factors in inflammatory lung diseases
    • Rahman I, MacNee W. Role of transcription factors in inflammatory lung diseases. Thorax 1998; 53: 601-612.
    • (1998) Thorax , vol.53 , pp. 601-612
    • Rahman, I.1    MacNee, W.2
  • 31
    • 0037474269 scopus 로고    scopus 로고
    • NF-κB and IκBα are found in the mitochondria
    • Cogswell PC, Kashatus DF, Keifer JA i wsp. NF-κB and IκBα are found in the mitochondria. J Biol Chem 2003; 278: 2963-2968.
    • (2003) J Biol Chem , vol.278 , pp. 2963-2968
    • Cogswell, P.C.1    Kashatus, D.F.2    Keifer, J.A.3
  • 32
    • 0035877820 scopus 로고    scopus 로고
    • IκBα, the NF-κB inhibitory subunit, interacts with ANT, the mitochondrial ATP/ADP translocator
    • Bottero V, Rossi F, Samson M i wsp. IκBα, the NF-κB inhibitory subunit, interacts with ANT, the mitochondrial ATP/ADP translocator. J Biol Chem 2001; 276: 21317-221324.
    • (2001) J Biol Chem , vol.276 , pp. 21317-221324
    • Bottero, V.1    Rossi, F.2    Samson, M.3
  • 33
    • 0034885358 scopus 로고    scopus 로고
    • New insights into the role of Nuclear Factor-κB in cell growth regulation
    • Chen F, Castranova V, Shi X. New insights into the role of Nuclear Factor-κB in cell growth regulation. Am J Pathol 2001; 159: 387-397.
    • (2001) Am J Pathol , vol.159 , pp. 387-397
    • Chen, F.1    Castranova, V.2    Shi, X.3
  • 34
    • 0035920176 scopus 로고    scopus 로고
    • A novel IκB protein, IκB-ζ, induced by proinflammatory stimuli, negatively regulates Nuclear Factor-κB in the nuclei
    • Yamazaki S, Muta T, Takeshige K. A novel IκB protein, IκB-ζ, induced by proinflammatory stimuli, negatively regulates Nuclear Factor-κB in the nuclei. J Biol Chem 2001; 276: 27657-27662.
    • (2001) J Biol Chem , vol.276 , pp. 27657-27662
    • Yamazaki, S.1    Muta, T.2    Takeshige, K.3
  • 35
    • 0033163393 scopus 로고    scopus 로고
    • Is NF-κB the sensor of oxidative stress?
    • Li N, Karin M. Is NF-κB the sensor of oxidative stress? FASEB J 1999; 13: 1137-1143.
    • (1999) FASEB J , vol.13 , pp. 1137-1143
    • Li, N.1    Karin, M.2
  • 36
    • 0030899121 scopus 로고    scopus 로고
    • I kappa B epsilon, a novel member of the IκB family, controls RelA and cRel NF-κB activity
    • Whiteside ST, Epinat JCh, Rice NR, Israel A. I kappa B epsilon, a novel member of the IκB family, controls RelA and cRel NF-κB activity. EMBO J 1997; 16: 1413-1426.
    • (1997) EMBO J , vol.16 , pp. 1413-1426
    • Whiteside, S.T.1    Epinat, J.Ch.2    Rice, N.R.3    Israel, A.4
  • 37
    • 0031593664 scopus 로고    scopus 로고
    • Role of NF-κB in immune and inflammatory responses in the gut
    • Neurath MF, Becker C, Barbulescu K.: Role of NF-κB in immune and inflammatory responses in the gut. Gut 1998; 43: 856-860.
    • (1998) Gut , vol.43 , pp. 856-860
    • Neurath, M.F.1    Becker, C.2    Barbulescu, K.3
  • 38
    • 0033524223 scopus 로고    scopus 로고
    • Mechanism by which IκB proteins control NF-κB activity
    • Simeonidis S, Stauber D, Chen G i wsp. Mechanism by which IκB proteins control NF-κB activity. Proc Natl Acad Sci USA 1999; 96: 49-54.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 49-54
    • Simeonidis, S.1    Stauber, D.2    Chen, G.3
  • 39
    • 0032555927 scopus 로고    scopus 로고
    • Functional redundancy of the Nuclear factor κB inhibitiors IκBα and IκBβ
    • Cheng JD, Ryseck RP, Attar RM. Functional redundancy of the Nuclear factor κB inhibitiors IκBα and IκBβ. J Exp Med 1998; 188: 1055-1062.
    • (1998) J Exp Med , vol.188 , pp. 1055-1062
    • Cheng, J.D.1    Ryseck, R.P.2    Attar, R.M.3
  • 40
    • 0035976962 scopus 로고    scopus 로고
    • IκBβ, but not IκBα functions as a classical cytoplasmatic inhibitor of NF-κB dimmers by masking both NF-κB nuclear localisation sequences in resting cells
    • Malek S, Chen Y, Huxford T, Ghosh G. IκBβ, but not IκBα functions as a classical cytoplasmatic inhibitor of NF-κB dimmers by masking both NF-κB nuclear localisation sequences in resting cells. J Biol Chem 2001; 276: 45225-45235.
    • (2001) J Biol Chem , vol.276 , pp. 45225-45235
    • Malek, S.1    Chen, Y.2    Huxford, T.3    Ghosh, G.4
  • 41
    • 0034741638 scopus 로고    scopus 로고
    • Nuclear factor κB for the nephrologist
    • Wardle EN. Nuclear factor κB for the nephrologist. Nephrol Dial Transplant 2001; 16: 1764-1768.
    • (2001) Nephrol Dial Transplant , vol.16 , pp. 1764-1768
    • Wardle, E.N.1
  • 42
    • 0034603021 scopus 로고    scopus 로고
    • A subclass of Ras proteins that regulate the degradation of IκB
    • Fenwick C, Na SY, Voll RE i wsp. A subclass of Ras proteins that regulate the degradation of IκB. Science 2000; 287: 869-873.
    • (2000) Science , vol.287 , pp. 869-873
    • Fenwick, C.1    Na, S.Y.2    Voll, R.E.3
  • 43
    • 0038495999 scopus 로고    scopus 로고
    • κB-Ras binds to the unique insert within the ankyrin repeat domain of IκB and regulates cytoplasmic retention of IκBβ:NF-κB complexes
    • Chen Y, Wu J, Gosh G. κB-Ras binds to the unique insert within the ankyrin repeat domain of IκB and regulates cytoplasmic retention of IκBβ:NF-κB complexes. J Biol Chem 2003; 278: 23101-23106.
    • (2003) J Biol Chem , vol.278 , pp. 23101-23106
    • Chen, Y.1    Wu, J.2    Gosh, G.3
  • 44
    • 0034960907 scopus 로고    scopus 로고
    • Postrepression activation of NF-κB requires the amino-terminal nuclear export signal specific to IκBα
    • Huang TT, Miyamoto S. Postrepression activation of NF-κB requires the amino-terminal nuclear export signal specific to IκBα. Mol Cell Biol 2001; 21: 4737-4747.
    • (2001) Mol Cell Biol , vol.21 , pp. 4737-4747
    • Huang, T.T.1    Miyamoto, S.2
  • 45
    • 0033600604 scopus 로고    scopus 로고
    • The beginning of the end: IκB Kinase (IKK) and NF-κB activation
    • Karin M. The beginning of the end: IκB Kinase (IKK) and NF-κB activation. J Biol Chem 1999; 274: 27339-27342.
    • (1999) J Biol Chem , vol.274 , pp. 27339-27342
    • Karin, M.1
  • 46
    • 3843134253 scopus 로고    scopus 로고
    • Rola białek wia̧ża̧cych FK506 w regulacji aktywnosci czynnikow transkrypcyjnych w komorkach T
    • Kochel I, Strza̧dała L. Rola białek wia̧ża̧cych FK506 w regulacji aktywnosci czynnikow transkrypcyjnych w komorkach T. Post Hig Med Dośw 2004; 58: 118-127.
    • (2004) Post Hig Med Dośw , vol.58 , pp. 118-127
    • Kochel, I.1    Strza̧dała, L.2
  • 47
    • 0033953587 scopus 로고    scopus 로고
    • A nuclear export signal in the N-terminal regulatory domain of IκBα controls cytoplasmic localization of inactive NF-κB/IκBα complexes
    • Huang TT, Kudo N, Yoshida M i wsp. A nuclear export signal in the N-terminal regulatory domain of IκBα controls cytoplasmic localization of inactive NF-κB/IκBα complexes. Proc Natl Acad Sci USA 2000; 97: 1014-1019.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 1014-1019
    • Huang, T.T.1    Kudo, N.2    Yoshida, M.3
  • 48
    • 3042834382 scopus 로고    scopus 로고
    • The IκB kinase complex and NF-κB act as master regulators of lipopolysaccharide - induced gene expression and control subordinate activation of AP-1
    • Krappmann D, Wegener E, Sunami Y i wsp. The IκB kinase complex and NF-κB act as master regulators of lipopolysaccharide - induced gene expression and control subordinate activation of AP-1. Mol Cell Biol 2004; 24: 6488-6500.
    • (2004) Mol Cell Biol , vol.24 , pp. 6488-6500
    • Krappmann, D.1    Wegener, E.2    Sunami, Y.3
  • 49
    • 0742304482 scopus 로고    scopus 로고
    • The role of Rel/NF-κB transcription factors in B lymphocyte survival
    • Gerondakis S, Strasser A. The role of Rel/NF-κB transcription factors in B lymphocyte survival. Semin Immunol 2003; 15, 159-166.
    • (2003) Semin Immunol , vol.15 , pp. 159-166
    • Gerondakis, S.1    Strasser, A.2
  • 50
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-κB
    • Hayden MS, Gosh S. Signaling to NF-κB. Genes Dev 2004; 18: 2195-2224.
    • (2004) Genes Dev , vol.18 , pp. 2195-2224
    • Hayden, M.S.1    Gosh, S.2
  • 51
    • 0036724051 scopus 로고    scopus 로고
    • The carboxyl-terminal region of IκB kinase γ(IKKγ) is required for full IKK activation
    • Makris C, Roberts JL, Karin M. The carboxyl-terminal region of IκB kinase γ(IKKγ) is required for full IKK activation. Mol Cell Biol 2002; 22: 6573-6581.
    • (2002) Mol Cell Biol , vol.22 , pp. 6573-6581
    • Makris, C.1    Roberts, J.L.2    Karin, M.3
  • 52
  • 53
    • 0030613551 scopus 로고
    • The IκB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation
    • Zandi E, Rothwarf DM, Delhase M i wsp. The IκB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation. Cell 1977; 91: 243-252.
    • (1977) Cell , vol.91 , pp. 243-252
    • Zandi, E.1    Rothwarf, D.M.2    Delhase, M.3
  • 54
    • 8544230698 scopus 로고    scopus 로고
    • A novel ubiquitin-like domain in IκB kinase β is required for functional activity of the kinase
    • May MJ, Larsen SE, Shim JH i wsp. A novel ubiquitin-like domain in IκB kinase β is required for functional activity of the kinase. J Biol Chem 2004; 279: 45528-45539.
    • (2004) J Biol Chem , vol.279 , pp. 45528-45539
    • May, M.J.1    Larsen, S.E.2    Shim, J.H.3
  • 55
    • 0032900439 scopus 로고    scopus 로고
    • New insights into the role of Nuclear Factor-κB, a ubiquitous transcription factor in the initiation of diseases
    • Chen F, Castranova V, Shi X, Deemrs LM. New insights into the role of Nuclear Factor-κB, a ubiquitous transcription factor in the initiation of diseases. Clin Chem. 1999; 45: 7-17.
    • (1999) Clin Chem , vol.45 , pp. 7-17
    • Chen, F.1    Castranova, V.2    Shi, X.3    Deemrs, L.M.4
  • 56
    • 0033002197 scopus 로고    scopus 로고
    • Bridging the gap: Composition, regulation, and physiological function of the IκB kinase complex
    • Zandi E, Karin M. Bridging the gap: composition, regulation, and physiological function of the IκB kinase complex. Mol Cell Biol 1999; 19: 4547-4551.
    • (1999) Mol Cell Biol , vol.19 , pp. 4547-4551
    • Zandi, E.1    Karin, M.2
  • 57
    • 0033591428 scopus 로고    scopus 로고
    • Phylogenetic perspectives in innate immunity
    • Hofmann JA, Kafatos FC, Janeway ChA. Phylogenetic perspectives in innate immunity. Science 1999; 284: 1313-1318.
    • (1999) Science , vol.284 , pp. 1313-1318
    • Hofmann, J.A.1    Kafatos, F.C.2    Janeway, Ch.A.3
  • 58
    • 4143144401 scopus 로고    scopus 로고
    • TNAP, a novel repressor of NF-κB-inducing kinase, suppresses NF-κB activation
    • Hu WH, Mo XM, Walters WM i wsp. TNAP, a novel repressor of NF-κB-inducing kinase, suppresses NF-κB activation. J Biol Chem 2004; 279: 35975-35983.
    • (2004) J Biol Chem , vol.279 , pp. 35975-35983
    • Hu, W.H.1    Mo, X.M.2    Walters, W.M.3
  • 59
    • 0037931474 scopus 로고    scopus 로고
    • RelB/p50 dinners are differentially regulated by Tumor Necrosis Factor-α and Lymphotoxin-β receptor activation
    • Derudder E, Dejardin E, Pritchard LL i wsp. RelB/p50 dinners are differentially regulated by Tumor Necrosis Factor-α and Lymphotoxin-β receptor activation. J Biol Chem 2003; 278: 23278-23284.
    • (2003) J Biol Chem , vol.278 , pp. 23278-23284
    • Derudder, E.1    Dejardin, E.2    Pritchard, L.L.3
  • 60
    • 0141567432 scopus 로고    scopus 로고
    • Regulation of secondary lymphoid organ development by the nuclear factor-κB signal transduction pathway
    • Weih F, Caamano J. Regulation of secondary lymphoid organ development by the nuclear factor-κB signal transduction pathway. Immunol Rev 2003; 195: 91-105.
    • (2003) Immunol Rev , vol.195 , pp. 91-105
    • Weih, F.1    Caamano, J.2
  • 61
    • 0037413709 scopus 로고    scopus 로고
    • RelB is required for Peyer's patch development: Differential regulation of p52-RelB by lymphotoxin and TNF
    • Yilmaz ZB, Weigh DS, Sivakumar V, Weih F. RelB is required for Peyer's patch development: differential regulation of p52-RelB by lymphotoxin and TNF. EMBO J 2003; 22: 121-13.
    • (2003) EMBO J , vol.22 , pp. 121-213
    • Yilmaz, Z.B.1    Weigh, D.S.2    Sivakumar, V.3    Weih, F.4
  • 62
    • 0033626350 scopus 로고    scopus 로고
    • Rel/NF-κB transcription factors: Key mediators of B-cell activation
    • Gugasyan R, Grumont R, Grossman M i wsp. Rel/NF-κB transcription factors: key mediators of B-cell activation. Immunol Rev 2000; 176: 134-140.
    • (2000) Immunol Rev , vol.176 , pp. 134-140
    • Gugasyan, R.1    Grumont, R.2    Grossman, M.3
  • 63
    • 0029664657 scopus 로고    scopus 로고
    • IκBα deficiency results in a sustained NF-κB responses and severe widespread dermatitis in mice
    • Klement JF, Rice NR, Abbondanzo SJ i wsp. IκBα deficiency results in a sustained NF-κB responses and severe widespread dermatitis in mice. Mol Cell Biol 1996; 16: 2341-2349.
    • (1996) Mol Cell Biol , vol.16 , pp. 2341-2349
    • Klement, J.F.1    Rice, N.R.2    Abbondanzo, S.J.3
  • 64
    • 0033563227 scopus 로고    scopus 로고
    • IKK1-deficient mice exhibit abnormal development of skin and skeleton
    • Li Q, Lu Q, Hwang JY i wsp. IKK1-deficient mice exhibit abnormal development of skin and skeleton. Genes Dev 1999; 13: 1322-1328.
    • (1999) Genes Dev , vol.13 , pp. 1322-1328
    • Li, Q.1    Lu, Q.2    Hwang, J.Y.3
  • 65
    • 0034175632 scopus 로고    scopus 로고
    • Severe liver degeneration and lack of NF-κB activation in NEMO/IKKγ-deficient mice
    • Rudolph D, Yeh WCh, Wakeham A i wsp. Severe liver degeneration and lack of NF-κB activation in NEMO/IKKγ-deficient mice. Genes Dev 2000; 14: 854-862.
    • (2000) Genes Dev , vol.14 , pp. 854-862
    • Rudolph, D.1    Yeh, W.Ch.2    Wakeham, A.3
  • 66
    • 0031755148 scopus 로고    scopus 로고
    • Nuclear Factor-κB: A pivotal role in the systemic inflammatory response syndrome and new target for therapy
    • Christman JW, Sadikot RT, Blackwell TS. Nuclear Factor-κB: a pivotal role in the systemic inflammatory response syndrome and new target for therapy. Intensive Care Med 1998; 24: 1131-1138.
    • (1998) Intensive Care Med , vol.24 , pp. 1131-1138
    • Christman, J.W.1    Sadikot, R.T.2    Blackwell, T.S.3
  • 67
    • 0037328613 scopus 로고    scopus 로고
    • NF-κB activation in cancer: A challenge for ubiquitination - and proteosome - based therapeutic approach
    • Amit S, Ben-Neriah Y. NF-κB activation in cancer: a challenge for ubiquitination - and proteosome - based therapeutic approach. Semin Cancer Biol 2003; 13: 15-28.
    • (2003) Semin Cancer Biol , vol.13 , pp. 15-28
    • Amit, S.1    Ben-Neriah, Y.2
  • 68
    • 0035097593 scopus 로고    scopus 로고
    • Signal transduction mechanisms as a new targets for allergists
    • Kowalski ML, Alam R. Signal transduction mechanisms as a new targets for allergists. Allergy 2001; 56: 199-203.
    • (2001) Allergy , vol.56 , pp. 199-203
    • Kowalski, M.L.1    Alam, R.2
  • 69
    • 13144261692 scopus 로고    scopus 로고
    • Human disease resulting from gene mutations that interfere with appropriate Nuclear Factor-κB activation
    • Orange JS, Levy O, Geha RS. Human disease resulting from gene mutations that interfere with appropriate Nuclear Factor-κB activation. Immunol Rev 2005; 203: 21-37.
    • (2005) Immunol Rev , vol.203 , pp. 21-37
    • Orange, J.S.1    Levy, O.2    Geha, R.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.