-
1
-
-
0015103371
-
Insulin receptors in the liver: specific binding of (125 I) insulin to the plasma membrane and its relation to insulin bioactivity
-
Freychet, P., Roth, J. and Neville, D. M., Jr. (1971) Insulin receptors in the liver: specific binding of (125 I) insulin to the plasma membrane and its relation to insulin bioactivity. Proc Natl Acad Sci USA 68, 1833-1837.
-
(1971)
Proc Natl Acad Sci USA
, vol.68
, pp. 1833-1837
-
-
Freychet, P.1
Roth, J.2
Neville, D.M.3
-
2
-
-
0001730479
-
Insulin-sensitive and insulin insensitive types of diabetes mellitus
-
Himsworth, H. P. and Kerr, R. B. (1939) Insulin-sensitive and insulin insensitive types of diabetes mellitus. Clin Sci 4, 119-152.
-
(1939)
Clin Sci
, vol.4
, pp. 119-152
-
-
Himsworth, H.P.1
Kerr, R.B.2
-
3
-
-
0001256804
-
Plasma insulin concentrations in nondiabetic and early diabetic subjects. Determinations by a new sensitive immuno-assay technic
-
Yalow, R. S. and Berson, S. A. (1960) Plasma insulin concentrations in nondiabetic and early diabetic subjects. Determinations by a new sensitive immuno-assay technic. Diabetes 9, 254-260.
-
(1960)
Diabetes
, vol.9
, pp. 254-260
-
-
Yalow, R.S.1
Berson, S.A.2
-
4
-
-
0032456709
-
Insulin resistance versus insulin deficiency in non-insulindependent diabetes mellitus: problems and prospects
-
Ferrannini, E. (1998) Insulin resistance versus insulin deficiency in non-insulindependent diabetes mellitus: problems and prospects. Endocr Rev 19, 477-490.
-
(1998)
Endocr Rev
, vol.19
, pp. 477-490
-
-
Ferrannini, E.1
-
5
-
-
0028091753
-
Metabolic and genetic characterization of prediabetic states. Sequence of events leading to non-insulin-dependent diabetes mellitus
-
Beck-Nielsen, H. and Groop, L. C. (1994) Metabolic and genetic characterization of prediabetic states. Sequence of events leading to non-insulin-dependent diabetes mellitus. J Clin Invest 94, 1714-1721.
-
(1994)
J Clin Invest
, vol.94
, pp. 1714-1721
-
-
Beck-Nielsen, H.1
Groop, L.C.2
-
6
-
-
0034496387
-
Pathophysiology and pharmacological treatment of insulin resistance
-
Matthaei, S., Stumvoll, M., Kellerer, M. and Haring, H. U. (2000) Pathophysiology and pharmacological treatment of insulin resistance. Endocr Rev 21, 585-618.
-
(2000)
Endocr Rev
, vol.21
, pp. 585-618
-
-
Matthaei, S.1
Stumvoll, M.2
Kellerer, M.3
Haring, H.U.4
-
7
-
-
0029037649
-
Pathophysiology of insulin resistance in human disease
-
Reaven, G. M. (1995) Pathophysiology of insulin resistance in human disease. Physiol Rev 75, 473-486.
-
(1995)
Physiol Rev
, vol.75
, pp. 473-486
-
-
Reaven, G.M.1
-
8
-
-
0034485313
-
Insulin sensitivity and its measurement: structural commonalities among the methods
-
Radziuk, J. (2000) Insulin sensitivity and its measurement: structural commonalities among the methods. J Clin Endocrinol Metab 85, 4426-4433.
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 4426-4433
-
-
Radziuk, J.1
-
9
-
-
0036425092
-
The assessment of insulin resistance in man
-
Wallace, T. M. and Matthews, D. R. (2002) The assessment of insulin resistance in man. Diabet Med 19, 527-534.
-
(2002)
Diabet Med
, vol.19
, pp. 527-534
-
-
Wallace, T.M.1
Matthews, D.R.2
-
10
-
-
0022361971
-
Assessment of insulin sensitivity in vivo
-
Bergman, R. N., Finegood, D. T. and Ader, M. (1985) Assessment of insulin sensitivity in vivo. Endocr Rev 6, 45-86.
-
(1985)
Endocr Rev
, vol.6
, pp. 45-86
-
-
Bergman, R.N.1
Finegood, D.T.2
Ader, M.3
-
11
-
-
0029761076
-
Role of glucose effectiveness in the determination of glucose tolerance
-
Best, J. D., Kahn, S. E., Ader, M., Watanabe, R. M., Ni, T. C. and Bergman, R. N. (1996) Role of glucose effectiveness in the determination of glucose tolerance. Diabetes Care 19, 1018-1030.
-
(1996)
Diabetes Care
, vol.19
, pp. 1018-1030
-
-
Best, J.D.1
Kahn, S.E.2
Ader, M.3
Watanabe, R.M.4
Ni, T.C.5
Bergman, R.N.6
-
12
-
-
0027375768
-
Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function
-
Kahn, S. E., Prigeon, R. L., McCulloch, D. K., Boyko, E. J., Bergman, R. N., Schwartz, M. W., Neifing, J. L., Ward, W. K., Beard, J. C. and Palmer, J. P., et al. (1993) Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function. Diabetes 42, 1663-1672.
-
(1993)
Diabetes
, vol.42
, pp. 1663-1672
-
-
Kahn, S.E.1
Prigeon, R.L.2
McCulloch, D.K.3
Boyko, E.J.4
Bergman, R.N.5
Schwartz, M.W.6
Neifing, J.L.7
Ward, W.K.8
Beard, J.C.9
Palmer, J.P.10
-
13
-
-
0021813187
-
Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
-
Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F. and Turner, R. C. (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28, 412-419.
-
(1985)
Diabetologia
, vol.28
, pp. 412-419
-
-
Matthews, D.R.1
Hosker, J.P.2
Rudenski, A.S.3
Naylor, B.A.4
Treacher, D.F.5
Turner, R.C.6
-
14
-
-
0034456568
-
Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans
-
Katz, A., Nambi, S. S., Mather, K., Baron, A. D., Follmann, D. A., Sullivan, G. and Quon, M. J. (2000) Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab 85, 2402-2410.
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 2402-2410
-
-
Katz, A.1
Nambi, S.S.2
Mather, K.3
Baron, A.D.4
Follmann, D.A.5
Sullivan, G.6
Quon, M.J.7
-
15
-
-
0018520840
-
Glucose clamp technique: a method for quantifying insulin secretion and resistance
-
DeFronzo, R. A., Tobin, J. D. and Andres, R. (1979) Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 237, E214-E223.
-
(1979)
Am J Physiol
, vol.237
, pp. E214-E223
-
-
DeFronzo, R.A.1
Tobin, J.D.2
Andres, R.3
-
16
-
-
0029920988
-
Effects of insulin on glucose turnover rates in vivo: isotope dilution versus constant specific activity technique
-
Hother-Nielsen, O., Henriksen, J. E., Holst, J. J. and Beck Nielsen, H. (1996) Effects of insulin on glucose turnover rates in vivo: isotope dilution versus constant specific activity technique. Metabolism 45, 82-91.
-
(1996)
Metabolism
, vol.45
, pp. 82-91
-
-
Hother-Nielsen, O.1
Henriksen, J.E.2
Holst, J.J.3
Beck Nielsen, H.4
-
17
-
-
0027935947
-
How to measure insulin action in vivo
-
Scheen, A. J., Paquot, N., Castillo, M. J. and Lefebvre, P. J. (1994) How to measure insulin action in vivo. Diabetes Metab Rev 10, 151-188.
-
(1994)
Diabetes Metab Rev
, vol.10
, pp. 151-188
-
-
Scheen, A.J.1
Paquot, N.2
Castillo, M.J.3
Lefebvre, P.J.4
-
18
-
-
0030017082
-
Contributions of gluconeogenesis to glucose production in the fasted state
-
Landau, B. R., Wahren, J., Chandramouli, V., Schumann, W. C., Ekberg, K. and Kalhan, S. C. (1996) Contributions of gluconeogenesis to glucose production in the fasted state. J Clin Invest 98, 378-385.
-
(1996)
J Clin Invest
, vol.98
, pp. 378-385
-
-
Landau, B.R.1
Wahren, J.2
Chandramouli, V.3
Schumann, W.C.4
Ekberg, K.5
Kalhan, S.C.6
-
19
-
-
0031426379
-
Quantifying gluconeogenesis during fasting
-
Chandramouli, V., Ekberg, K., Schumann, W. C., Kalhan, S. C., Wahren, J. and Landau, B. R. (1997) Quantifying gluconeogenesis during fasting. Am J Physiol 273, E1209-E1215.
-
(1997)
Am J Physiol
, vol.273
, pp. E1209-E1215
-
-
Chandramouli, V.1
Ekberg, K.2
Schumann, W.C.3
Kalhan, S.C.4
Wahren, J.5
Landau, B.R.6
-
20
-
-
0023930822
-
The theoretical bases of indirect calorimetry: a review
-
Ferrannini, E. (1988) The theoretical bases of indirect calorimetry: a review. Metabolism 37, 287-301.
-
(1988)
Metabolism
, vol.37
, pp. 287-301
-
-
Ferrannini, E.1
-
21
-
-
0034076660
-
Fuel selection in human skeletal muscle in insulin resistance: a reexamination
-
Kelley, D. E. and Mandarino, L. J. (2000) Fuel selection in human skeletal muscle in insulin resistance: a reexamination. Diabetes 49, 677-683.
-
(2000)
Diabetes
, vol.49
, pp. 677-683
-
-
Kelley, D.E.1
Mandarino, L.J.2
-
22
-
-
0025376250
-
Relative contribution of glycogen synthesis and glycolysis to insulin-mediated glucose uptake. A dose-response euglycemic clamp study in normal and diabetic rats
-
Rossetti, L. and Giaccari, A. (1990) Relative contribution of glycogen synthesis and glycolysis to insulin-mediated glucose uptake. A dose-response euglycemic clamp study in normal and diabetic rats. J Clin Invest 85, 1785-1792.
-
(1990)
J Clin Invest
, vol.85
, pp. 1785-1792
-
-
Rossetti, L.1
Giaccari, A.2
-
23
-
-
0033856104
-
Plasma FFA utilization and fatty acid-binding protein content are diminished in type 2 diabetic muscle
-
Blaak, E. E., Wagenmakers, A. J., Glatz, J. F., Wolffenbuttel, B. H., Kemerink, G. J., Langenberg, C. J., Heidendal, G. A. and Saris, W. H. (2000) Plasma FFA utilization and fatty acid-binding protein content are diminished in type 2 diabetic muscle. Am J Physiol Endocrinol Metab 279, E146-E154.
-
(2000)
Am J Physiol Endocrinol Metab
, vol.279
, pp. E146-E154
-
-
Blaak, E.E.1
Wagenmakers, A.J.2
Glatz, J.F.3
Wolffenbuttel, B.H.4
Kemerink, G.J.5
Langenberg, C.J.6
Heidendal, G.A.7
Saris, W.H.8
-
24
-
-
0028155857
-
Impact of variable insulinemia and glycemia on in vivo glycolysis and glucose storage in dogs
-
Christopher, M. J., Rantzau, C., Ward, G. M. and Alford, F. P. (1994) Impact of variable insulinemia and glycemia on in vivo glycolysis and glucose storage in dogs. Am J Physiol 266, E62-71.
-
(1994)
Am J Physiol
, vol.266
, pp. E62-71
-
-
Christopher, M.J.1
Rantzau, C.2
Ward, G.M.3
Alford, F.P.4
-
25
-
-
0027140676
-
Quantitation of glycolysis and skeletal muscle glycogen synthesis in humans
-
Rossetti, L., Lee, Y. T., Ruiz, J., Aldridge, S. C., Shamoon, H. and Boden, G. (1993) Quantitation of glycolysis and skeletal muscle glycogen synthesis in humans. Am J Physiol 265, E761-E769.
-
(1993)
Am J Physiol
, vol.265
, pp. E761-E769
-
-
Rossetti, L.1
Lee, Y.T.2
Ruiz, J.3
Aldridge, S.C.4
Shamoon, H.5
Boden, G.6
-
26
-
-
0027500242
-
Characterization of cellular defects of insulin action in type 2 (non-insulin-dependent) diabetes mellitus
-
Del Prato, S., Bonadonna, R. C., Bonora, E., Gulli, G., Solini, A., Shank, M. and DeFronzo, R. A. (1993) Characterization of cellular defects of insulin action in type 2 (non-insulin-dependent) diabetes mellitus. J Clin Invest 91, 484-494.
-
(1993)
J Clin Invest
, vol.91
, pp. 484-494
-
-
Del Prato, S.1
Bonadonna, R.C.2
Bonora, E.3
Gulli, G.4
Solini, A.5
Shank, M.6
DeFronzo, R.A.7
-
27
-
-
0028819524
-
Multiple defects of both hepatic and peripheral intracellular glucose processing contribute to the hyperglycaemia of NIDDM
-
Vaag, A., Alford, F., Henriksen, F. L., Christopher, M. and Beck Nielsen, H. (1995) Multiple defects of both hepatic and peripheral intracellular glucose processing contribute to the hyperglycaemia of NIDDM. Diabetologia 38, 326-336.
-
(1995)
Diabetologia
, vol.38
, pp. 326-336
-
-
Vaag, A.1
Alford, F.2
Henriksen, F.L.3
Christopher, M.4
Beck Nielsen, H.5
-
28
-
-
0018487598
-
Quantitative estimation of insulin sensitivity
-
Bergman, R. N., Ider, Y. Z., Bowden, C. R. and Cobelli, C. (1979) Quantitative estimation of insulin sensitivity. Am J Physiol 236, E667-E677.
-
(1979)
Am J Physiol
, vol.236
, pp. E667-E677
-
-
Bergman, R.N.1
Ider, Y.Z.2
Bowden, C.R.3
Cobelli, C.4
-
29
-
-
0024542734
-
Alternative method for minimal model analysis of intravenous glucose tolerance data
-
Weber, K. M., Martin, I. K., Best, J. D., Alford, F. P. and Boston, R. C. (1989) Alternative method for minimal model analysis of intravenous glucose tolerance data. Am J Physiol 256, E524-E535.
-
(1989)
Am J Physiol
, vol.256
, pp. E524-E535
-
-
Weber, K.M.1
Martin, I.K.2
Best, J.D.3
Alford, F.P.4
Boston, R.C.5
-
30
-
-
0029823503
-
Reduced glucose effectiveness associated with reduced insulin release: an artifact of the minimal-model method
-
Finegood, D. T. and Tzur, D. (1996) Reduced glucose effectiveness associated with reduced insulin release: an artifact of the minimal-model method. Am J Physiol 271, E485-E495.
-
(1996)
Am J Physiol
, vol.271
, pp. E485-E495
-
-
Finegood, D.T.1
Tzur, D.2
-
31
-
-
0030659571
-
The hot IVGTT two-compartment minimal model: indexes of glucose effectiveness and insulin sensitivity
-
Vicini, P., Caumo, A. and Cobelli, C. (1997) The hot IVGTT two-compartment minimal model: indexes of glucose effectiveness and insulin sensitivity. Am J Physiol 273, E1024-E1032.
-
(1997)
Am J Physiol
, vol.273
, pp. E1024-E1032
-
-
Vicini, P.1
Caumo, A.2
Cobelli, C.3
-
32
-
-
0023120630
-
Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycemic glucose clamp
-
Bergman, R. N., Prager, R., Volund, A. and Olefsky, J. M. (1987) Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycemic glucose clamp. J Clin Invest 79, 790-800.
-
(1987)
J Clin Invest
, vol.79
, pp. 790-800
-
-
Bergman, R.N.1
Prager, R.2
Volund, A.3
Olefsky, J.M.4
-
33
-
-
0029928227
-
Glucose processing during the intravenous glucose tolerance test
-
Henriksen, J. E., Alford, F., Handberg, A., Vaag, A. and Beck Nielsen, H. (1996) Glucose processing during the intravenous glucose tolerance test. Metabolism 45, 598-605.
-
(1996)
Metabolism
, vol.45
, pp. 598-605
-
-
Henriksen, J.E.1
Alford, F.2
Handberg, A.3
Vaag, A.4
Beck Nielsen, H.5
-
34
-
-
0035340048
-
Physiologic modeling of the intravenous glucose tolerance test in type 2 diabetes: a new approach to the insulin compartment
-
Ward, G. M., Walters, J. M., Barton, J., Alford, F. P. and Boston, R. C. (2001) Physiologic modeling of the intravenous glucose tolerance test in type 2 diabetes: a new approach to the insulin compartment. Metabolism 50, 512-519.
-
(2001)
Metabolism
, vol.50
, pp. 512-519
-
-
Ward, G.M.1
Walters, J.M.2
Barton, J.3
Alford, F.P.4
Boston, R.C.5
-
35
-
-
0025960849
-
A modified minimal model analysis of insulin sensitivity and glucose-mediated glucose disposal in insulin-dependent diabetes
-
Ward, G. M., Weber, K. M., Walters, I. M., Aitken, P. M., Lee, B., Best, J. D., Boston, R. C. and Alford, F. P. (1991) A modified minimal model analysis of insulin sensitivity and glucose-mediated glucose disposal in insulin-dependent diabetes. Metabolism 40, 4-9.
-
(1991)
Metabolism
, vol.40
, pp. 4-9
-
-
Ward, G.M.1
Weber, K.M.2
Walters, I.M.3
Aitken, P.M.4
Lee, B.5
Best, J.D.6
Boston, R.C.7
Alford, F.P.8
-
36
-
-
0027965661
-
Increased glucose effectiveness in normoglycemic but insulinresistant relatives of patients with non-insulin-dependent diabetes mellitus. A novel compensatory mechanism
-
Henriksen, J. E., Alford, F., Handberg, A., Vaag, A., Ward, G. M., Kalfas, A. and Beck-Nielsen, H. (1994) Increased glucose effectiveness in normoglycemic but insulinresistant relatives of patients with non-insulin-dependent diabetes mellitus. A novel compensatory mechanism. J Clin Invest 94, 1196-1204.
-
(1994)
J Clin Invest
, vol.94
, pp. 1196-1204
-
-
Henriksen, J.E.1
Alford, F.2
Handberg, A.3
Vaag, A.4
Ward, G.M.5
Kalfas, A.6
Beck-Nielsen, H.7
-
37
-
-
0026793446
-
Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study
-
Martin, B. C., Warram, J. H., Krolewski, A. S., Bergman, R. N., Soeldner, J. S. and Kahn, C. R. (1992) Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study. Lancet 340, 925-929.
-
(1992)
Lancet
, vol.340
, pp. 925-929
-
-
Martin, B.C.1
Warram, J.H.2
Krolewski, A.S.3
Bergman, R.N.4
Soeldner, J.S.5
Kahn, C.R.6
-
38
-
-
0026474342
-
A simple method for quantitation of insulin sensitivity and insulin release from an intravenous glucose tolerance test
-
Galvin, P., Ward, G., Walters, J., Pestell, R., Koschmann, M., Vaag, A., Martin, I., Best, J. D. and Alford, F. (1992) A simple method for quantitation of insulin sensitivity and insulin release from an intravenous glucose tolerance test. Diabet Med 9, 921-928.
-
(1992)
Diabet Med
, vol.9
, pp. 921-928
-
-
Galvin, P.1
Ward, G.2
Walters, J.3
Pestell, R.4
Koschmann, M.5
Vaag, A.6
Martin, I.7
Best, J.D.8
Alford, F.9
-
39
-
-
0029113443
-
Exploration of simple insulin sensitivity measures derived from frequently sampled intravenous glucose tolerance (FSIGT) tests. The Insulin Resistance Atherosclerosis Study
-
Anderson, R. L., Hamman, R. F., Savage, P. J., Saad, M. F., Laws, A., Kades, W. W., Sands, R. E. and Cefalu, W. (1995) Exploration of simple insulin sensitivity measures derived from frequently sampled intravenous glucose tolerance (FSIGT) tests. The Insulin Resistance Atherosclerosis Study. Am J Epidemiol 142, 724-732.
-
(1995)
Am J Epidemiol
, vol.142
, pp. 724-732
-
-
Anderson, R.L.1
Hamman, R.F.2
Savage, P.J.3
Saad, M.F.4
Laws, A.5
Kades, W.W.6
Sands, R.E.7
Cefalu, W.8
-
40
-
-
0031851293
-
Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation [see comments]
-
Alberti, K. G. and Zimmet, P. Z. (1998) Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation [see comments]. Diabet Med 15, 539-553.
-
(1998)
Diabet Med
, vol.15
, pp. 539-553
-
-
Alberti, K.G.1
Zimmet, P.Z.2
-
41
-
-
0034981290
-
Assessment of hepatic insulin action in obese type 2 diabetic patients
-
Staehr, P., Hother-Nielsen, O., Levin, K., Holst, J. J. and Beck-Nielsen, H. (2001) Assessment of hepatic insulin action in obese type 2 diabetic patients. Diabetes 50, 1363-1370.
-
(2001)
Diabetes
, vol.50
, pp. 1363-1370
-
-
Staehr, P.1
Hother-Nielsen, O.2
Levin, K.3
Holst, J.J.4
Beck-Nielsen, H.5
-
42
-
-
0025098765
-
Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy
-
Shulman, G. I., Rothman, D. L., Jue, T., Stein, P., DeFronzo, R. A. and Shulman, R. G. (1990) Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy. N Engl J Med 322, 223-228.
-
(1990)
N Engl J Med
, vol.322
, pp. 223-228
-
-
Shulman, G.I.1
Rothman, D.L.2
Jue, T.3
Stein, P.4
DeFronzo, R.A.5
Shulman, R.G.6
-
43
-
-
0019762341
-
The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization
-
DeFronzo, R. A., Jacot, E., Jequier, E., Maeder, E., Wahren, J. and Felber, J. P. (1981) The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization. Diabetes 30, 1000-1007.
-
(1981)
Diabetes
, vol.30
, pp. 1000-1007
-
-
DeFronzo, R.A.1
Jacot, E.2
Jequier, E.3
Maeder, E.4
Wahren, J.5
Felber, J.P.6
-
44
-
-
0019935341
-
The effect of graded doses of insulin on total glucose uptake, glucose oxidation, and glucose storage in man
-
Thiebaud, D., Jacot, E., DeFronzo, R. A., Maeder, E., Jequier, E. and Felber, J. P. (1982) The effect of graded doses of insulin on total glucose uptake, glucose oxidation, and glucose storage in man. Diabetes 31, 957-963.
-
(1982)
Diabetes
, vol.31
, pp. 957-963
-
-
Thiebaud, D.1
Jacot, E.2
DeFronzo, R.A.3
Maeder, E.4
Jequier, E.5
Felber, J.P.6
-
45
-
-
0023508465
-
Effects of insulin infusion on human skeletal muscle pyruvate dehydrogenase, phosphofructokinase, and glycogen synthase. Evidence for their role in oxidative and nonoxidative glucose metabolism
-
Mandarino, L. J., Wright, K. S., Verity, L. S., Nichols, J., Bell, J. M., Kolterman, O. G. and Beck-Nielsen, H. (1987) Effects of insulin infusion on human skeletal muscle pyruvate dehydrogenase, phosphofructokinase, and glycogen synthase. Evidence for their role in oxidative and nonoxidative glucose metabolism. J Clin Invest 80, 655-663.
-
(1987)
J Clin Invest
, vol.80
, pp. 655-663
-
-
Mandarino, L.J.1
Wright, K.S.2
Verity, L.S.3
Nichols, J.4
Bell, J.M.5
Kolterman, O.G.6
Beck-Nielsen, H.7
-
46
-
-
0023864887
-
Muscle glycogen synthesis and disposition of infused glucose in humans with reduced rates of insulinmediated carbohydrate storage
-
Young, A. A., Bogardus, C., Wolfe Lopez, D. and Mott, D. M. (1988) Muscle glycogen synthesis and disposition of infused glucose in humans with reduced rates of insulinmediated carbohydrate storage. Diabetes 37, 303-308.
-
(1988)
Diabetes
, vol.37
, pp. 303-308
-
-
Young, A.A.1
Bogardus, C.2
Wolfe Lopez, D.3
Mott, D.M.4
-
47
-
-
0025061075
-
Effect of hyperinsulinemia and hyperglycemia on intracellular glucose and fat metabolism in healthy subjects
-
Thorburn, A. W., Gumbiner, B., Brechtel, G. and Henry, R. R. (1990) Effect of hyperinsulinemia and hyperglycemia on intracellular glucose and fat metabolism in healthy subjects. Diabetes 39, 22-30.
-
(1990)
Diabetes
, vol.39
, pp. 22-30
-
-
Thorburn, A.W.1
Gumbiner, B.2
Brechtel, G.3
Henry, R.R.4
-
48
-
-
1842324009
-
Hyperglycemia stimulates carbohydrate oxidation in humans
-
Yki-Jarvinen, H., Bogardus, C. and Howard, B. V. (1987) Hyperglycemia stimulates carbohydrate oxidation in humans. Am J Physiol 253, E376-E382.
-
(1987)
Am J Physiol
, vol.253
, pp. E376-E382
-
-
Yki-Jarvinen, H.1
Bogardus, C.2
Howard, B.V.3
-
49
-
-
0034945787
-
Morphometric documentation of abnormal intramyocellular fat storage and reduced glycogen in obese patients with Type II diabetes
-
Levin, K., Daa, S. H., Alford, F. P. and Beck-Nielsen, H. (2001) Morphometric documentation of abnormal intramyocellular fat storage and reduced glycogen in obese patients with Type II diabetes. Diabetologia 44, 824-833.
-
(2001)
Diabetologia
, vol.44
, pp. 824-833
-
-
Levin, K.1
Daa, S.H.2
Alford, F.P.3
Beck-Nielsen, H.4
-
50
-
-
0025860114
-
Reduced glycogen synthase activity in skeletal muscle from obese patients with and without type 2 (non-insulin-dependent) diabetes mellitus
-
Damsbo, P., Vaag, A., Hother-Nielsen, O. and Beck-Nielsen, H. (1991) Reduced glycogen synthase activity in skeletal muscle from obese patients with and without type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 34, 239-245.
-
(1991)
Diabetologia
, vol.34
, pp. 239-245
-
-
Damsbo, P.1
Vaag, A.2
Hother-Nielsen, O.3
Beck-Nielsen, H.4
-
51
-
-
0038321327
-
Increased phosphorylation of skeletal muscle glycogen synthase at NH2-terminal sites during physiological hyperinsulinemia in type 2 diabetes
-
Højlund, K., Staehr, P., Hansen, B. F., Green, K. A., Hardie, D. G., Richter, E. A., Beck-Nielsen, H. and Wojtaszewski, J. F. (2003) Increased phosphorylation of skeletal muscle glycogen synthase at NH2-terminal sites during physiological hyperinsulinemia in type 2 diabetes. Diabetes 52, 1393-1402.
-
(2003)
Diabetes
, vol.52
, pp. 1393-1402
-
-
Højlund, K.1
Staehr, P.2
Hansen, B.F.3
Green, K.A.4
Hardie, D.G.5
Richter, E.A.6
Beck-Nielsen, H.7
Wojtaszewski, J.F.8
-
52
-
-
0029791119
-
Intracellular glucose and fat metabolism in identical twins discordant for non-insulin-dependent diabetes mellitus (NIDDM): acquired versus genetic metabolic defects?
-
Vaag, A., Alford, F. and Beck-Nielsen, H. (1996) Intracellular glucose and fat metabolism in identical twins discordant for non-insulin-dependent diabetes mellitus (NIDDM): acquired versus genetic metabolic defects? Diabet Med 13, 806-815.
-
(1996)
Diabet Med
, vol.13
, pp. 806-815
-
-
Vaag, A.1
Alford, F.2
Beck-Nielsen, H.3
-
53
-
-
0023726257
-
Oxidative and nonoxidative glucose metabolism in non-obese type 2 (non-insulin-dependent) diabetic patients
-
Golay, A., DeFronzo, R. A., Ferrannini, E., Simonson, D. C., Thorin, D., Acheson, K., Thiebaud, D., Curchod, B., Jequier, E. and Felber, J. P. (1988) Oxidative and nonoxidative glucose metabolism in non-obese type 2 (non-insulin-dependent) diabetic patients. Diabetologia 31, 585-591.
-
(1988)
Diabetologia
, vol.31
, pp. 585-591
-
-
Golay, A.1
DeFronzo, R.A.2
Ferrannini, E.3
Simonson, D.C.4
Thorin, D.5
Acheson, K.6
Thiebaud, D.7
Curchod, B.8
Jequier, E.9
Felber, J.P.10
-
54
-
-
0024392514
-
Glucose and free fatty acid metabolism in non-insulindependent diabetes mellitus. Evidence for multiple sites of insulin resistance
-
Groop, L. C., Bonadonna, R. C., DelPrato, S., Ratheiser, K., Zyck, K., Ferrannini, E. and DeFronzo, R. A. (1989) Glucose and free fatty acid metabolism in non-insulindependent diabetes mellitus. Evidence for multiple sites of insulin resistance. J Clin Invest 84, 205-213.
-
(1989)
J Clin Invest
, vol.84
, pp. 205-213
-
-
Groop, L.C.1
Bonadonna, R.C.2
DelPrato, S.3
Ratheiser, K.4
Zyck, K.5
Ferrannini, E.6
DeFronzo, R.A.7
-
55
-
-
0023692532
-
Regulation of glucose storage in obesity and diabetes: metabolic aspects
-
Felber, J. P., Golay, A., Felley, C. and Jequier, E. (1988) Regulation of glucose storage in obesity and diabetes: metabolic aspects. Diabetes Metab Rev 4, 691-700.
-
(1988)
Diabetes Metab Rev
, vol.4
, pp. 691-700
-
-
Felber, J.P.1
Golay, A.2
Felley, C.3
Jequier, E.4
-
56
-
-
0025014823
-
Intracellular glucose oxidation and glycogen synthase activity are reduced in noninsulin-dependent (type II) diabetes independent of impaired glucose uptake
-
Thorburn, A. W., Gumbiner, B., Bulacan, F., Wallace, P. and Henry, R. R. (1990) Intracellular glucose oxidation and glycogen synthase activity are reduced in noninsulin-dependent (type II) diabetes independent of impaired glucose uptake. J Clin Invest 85, 522-529.
-
(1990)
J Clin Invest
, vol.85
, pp. 522-529
-
-
Thorburn, A.W.1
Gumbiner, B.2
Bulacan, F.3
Wallace, P.4
Henry, R.R.5
-
57
-
-
50549202600
-
The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
-
Randle, P. J., Garland, P. B., Hales, C. N. and Newsholme, E. A. (1963) The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1, 785-789.
-
(1963)
Lancet
, vol.1
, pp. 785-789
-
-
Randle, P.J.1
Garland, P.B.2
Hales, C.N.3
Newsholme, E.A.4
-
58
-
-
0026002683
-
Effects of fat on insulin-stimulated carbohydrate metabolism in normal men
-
Boden, G., Jadali, F., White, J., Liang, Y., Mozzoli, M., Chen, X., Coleman, E. and Smith, C. (1991) Effects of fat on insulin-stimulated carbohydrate metabolism in normal men. J Clin Invest 88, 960-966.
-
(1991)
J Clin Invest
, vol.88
, pp. 960-966
-
-
Boden, G.1
Jadali, F.2
White, J.3
Liang, Y.4
Mozzoli, M.5
Chen, X.6
Coleman, E.7
Smith, C.8
-
59
-
-
0029948212
-
Mechanism of free fatty acid-induced insulin resistance in humans
-
Roden, M., Price, T. B., Perseghin, G., Petersen, K. F., Rothman, D. L., Cline, G. W. and Shulman, G. I. (1996) Mechanism of free fatty acid-induced insulin resistance in humans. J Clin Invest 97, 2859-2865.
-
(1996)
J Clin Invest
, vol.97
, pp. 2859-2865
-
-
Roden, M.1
Price, T.B.2
Perseghin, G.3
Petersen, K.F.4
Rothman, D.L.5
Cline, G.W.6
Shulman, G.I.7
-
60
-
-
0027218865
-
Interaction between glucose and free fatty acid metabolism in human skeletal muscle
-
Kelley, D. E., Mokan, M., Simoneau, J. A. and Mandarino, L. J. (1993) Interaction between glucose and free fatty acid metabolism in human skeletal muscle. J Clin Invest 92, 91-98.
-
(1993)
J Clin Invest
, vol.92
, pp. 91-98
-
-
Kelley, D.E.1
Mokan, M.2
Simoneau, J.A.3
Mandarino, L.J.4
-
61
-
-
0000044662
-
The quantitative minor role of oxidative metabolism by skeletal muscle in intact man in the basal state
-
Andres, R., Cadar, G. and Zierler, K. (1956) The quantitative minor role of oxidative metabolism by skeletal muscle in intact man in the basal state. J Clin Invest 35, 671-682.
-
(1956)
J Clin Invest
, vol.35
, pp. 671-682
-
-
Andres, R.1
Cadar, G.2
Zierler, K.3
-
62
-
-
0028960787
-
Skeletal muscle utilization of free fatty acids in women with visceral obesity [see comments]
-
Colberg, S. R., Simoneau, J. A., Thaete, F. L. and Kelley, D. E. (1995) Skeletal muscle utilization of free fatty acids in women with visceral obesity [see comments]. J Clin Invest 95, 1846-1853.
-
(1995)
J Clin Invest
, vol.95
, pp. 1846-1853
-
-
Colberg, S.R.1
Simoneau, J.A.2
Thaete, F.L.3
Kelley, D.E.4
-
63
-
-
0033400310
-
Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss
-
Kelley, D. E., Goodpaster, B., Wing, R. R. and Simoneau, J. A. (1999) Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss. Am J Physiol 277, E1130-E1141.
-
(1999)
Am J Physiol
, vol.277
, pp. E1130-E1141
-
-
Kelley, D.E.1
Goodpaster, B.2
Wing, R.R.3
Simoneau, J.A.4
-
64
-
-
0027946529
-
Impaired free fatty acid utilization by skeletal muscle in non-insulin-dependent diabetes mellitus
-
Kelley, D. E. and Simoneau, J. A. (1994) Impaired free fatty acid utilization by skeletal muscle in non-insulin-dependent diabetes mellitus. J Clin Invest 94, 2349-2356.
-
(1994)
J Clin Invest
, vol.94
, pp. 2349-2356
-
-
Kelley, D.E.1
Simoneau, J.A.2
-
65
-
-
0033927667
-
Cellular mechanisms of insulin resistance
-
Shulman, G. I. (2000) Cellular mechanisms of insulin resistance. J Clin Invest 106, 171-176.
-
(2000)
J Clin Invest
, vol.106
, pp. 171-176
-
-
Shulman, G.I.1
-
66
-
-
0033942001
-
Insulin action and insulin resistance in human skeletal muscle
-
Zierath, J. R., Krook, A. and Wallberg-Henriksson, H. (2000) Insulin action and insulin resistance in human skeletal muscle. Diabetologia 43, 821-835.
-
(2000)
Diabetologia
, vol.43
, pp. 821-835
-
-
Zierath, J.R.1
Krook, A.2
Wallberg-Henriksson, H.3
-
67
-
-
17644436207
-
GLUT4 translocation in human muscle strips
-
Lund, S., Pedersen, O., Holman, G. D., Clark, A. E., Zierath, J. R. and Wallberg-Henriksson, H. (1997) GLUT4 translocation in human muscle strips. Biochem Soc Trans 25, 466S.
-
(1997)
Biochem Soc Trans
, vol.25
, pp. 466S
-
-
Lund, S.1
Pedersen, O.2
Holman, G.D.3
Clark, A.E.4
Zierath, J.R.5
Wallberg-Henriksson, H.6
-
68
-
-
0032954778
-
Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity
-
Dresner, A., Laurent, D., Marcucci, M., Griffin, M. E., Dufour, S., Cline, G. W., Slezak, L. A., Andersen, D. K., Hundal, R. S., Rothman, D. L., Petersen, K. F. and Shulman, G. I. (1999) Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity. J Clin Invest 103, 253-259.
-
(1999)
J Clin Invest
, vol.103
, pp. 253-259
-
-
Dresner, A.1
Laurent, D.2
Marcucci, M.3
Griffin, M.E.4
Dufour, S.5
Cline, G.W.6
Slezak, L.A.7
Andersen, D.K.8
Hundal, R.S.9
Rothman, D.L.10
Petersen, K.F.11
Shulman, G.I.12
-
69
-
-
0343314906
-
Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients
-
Krook, A., Bjornholm, M., Galuska, D., Jiang, X. J., Fahlman, R., Myers, M. G., Jr., Wallberg-Henriksson, H. and Zierath, J. R. (2000) Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients. Diabetes 49, 284-292.
-
(2000)
Diabetes
, vol.49
, pp. 284-292
-
-
Krook, A.1
Bjornholm, M.2
Galuska, D.3
Jiang, X.J.4
Fahlman, R.5
Myers, M.G.6
Wallberg-Henriksson, H.7
Zierath, J.R.8
-
70
-
-
0036594230
-
Insulin signalling in human skeletal muscle of subjects with or without Type II-diabetes and first degree relatives of patients with the disease
-
Meyer, M. M., Levin, K., Grimmsmann, T., Beck-Nielsen, H. and Klein, H. H. (2002) Insulin signalling in human skeletal muscle of subjects with or without Type II-diabetes and first degree relatives of patients with the disease. Diabetologia 45, 813-822.
-
(2002)
Diabetologia
, vol.45
, pp. 813-822
-
-
Meyer, M.M.1
Levin, K.2
Grimmsmann, T.3
Beck-Nielsen, H.4
Klein, H.H.5
-
71
-
-
0036120053
-
Delays in insulin signaling towards glucose disposal in human skeletal muscle
-
Grimmsmann, T., Levin, K., Meyer, M. M., Beck-Nielsen, H. and Klein, H. H. (2002) Delays in insulin signaling towards glucose disposal in human skeletal muscle. J Endocrinol 172, 645-651.
-
(2002)
J Endocrinol
, vol.172
, pp. 645-651
-
-
Grimmsmann, T.1
Levin, K.2
Meyer, M.M.3
Beck-Nielsen, H.4
Klein, H.H.5
-
72
-
-
0031852665
-
Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects
-
Krook, A., Roth, R. A., Jiang, X. J., Zierath, J. R. and Wallberg-Henriksson, H. (1998) Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects. Diabetes 47, 1281-1286.
-
(1998)
Diabetes
, vol.47
, pp. 1281-1286
-
-
Krook, A.1
Roth, R.A.2
Jiang, X.J.3
Zierath, J.R.4
Wallberg-Henriksson, H.5
-
73
-
-
0034987199
-
GLUT4 is reduced in slow muscle fibers of type 2 diabetic patients: is insulin resistance in type 2 diabetes a slow, type 1 fiber disease?
-
Gaster, M., Staehr, P., Beck-Nielsen, H., Schroder, H. D. and Handberg, A. (2001) GLUT4 is reduced in slow muscle fibers of type 2 diabetic patients: is insulin resistance in type 2 diabetes a slow, type 1 fiber disease? Diabetes 50, 1324-1329.
-
(2001)
Diabetes
, vol.50
, pp. 1324-1329
-
-
Gaster, M.1
Staehr, P.2
Beck-Nielsen, H.3
Schroder, H.D.4
Handberg, A.5
-
74
-
-
0036224284
-
The diabetic phenotype is conserved in myotubes established from diabetic subjects: evidence for primary defects in glucose transport and glycogen synthase activity
-
Gaster, M., Petersen, I., Hojlund, K., Poulsen, P. and Beck-Nielsen, H. (2002) The diabetic phenotype is conserved in myotubes established from diabetic subjects: evidence for primary defects in glucose transport and glycogen synthase activity. Diabetes 51, 921-927.
-
(2002)
Diabetes
, vol.51
, pp. 921-927
-
-
Gaster, M.1
Petersen, I.2
Hojlund, K.3
Poulsen, P.4
Beck-Nielsen, H.5
-
75
-
-
0025089269
-
On the determination of basal glucose production rate in patients with type 2 (non-insulin-dependent) diabetes mellitus using primed-continuous 3-3H-glucose infusion
-
Hother-Nielsen, O. and Beck-Nielsen, H. (1990) On the determination of basal glucose production rate in patients with type 2 (non-insulin-dependent) diabetes mellitus using primed-continuous 3-3H-glucose infusion. Diabetologia 33, 603-610.
-
(1990)
Diabetologia
, vol.33
, pp. 603-610
-
-
Hother-Nielsen, O.1
Beck-Nielsen, H.2
-
76
-
-
0002721174
-
Constant tracer infusion technique for assessment of glucose turnover in vivo: current status
-
Marshall SM, Home PD, Rizza RA, eds., Amsterdam: Elsevier
-
Hother-Nielsen, O. (1996) Constant tracer infusion technique for assessment of glucose turnover in vivo: current status. In: Marshall SM, Home PD, Rizza RA, eds. Diabetes Annual/10. Amsterdam: Elsevier, 301-336.
-
(1996)
Diabetes Annual/10
, pp. 301-336
-
-
Hother-Nielsen, O.1
-
77
-
-
0036366985
-
Quantitation of basal endogenous glucose production in Type II diabetes: importance of the volume of distribution
-
Radziuk, J. and Pye, S. (2002) Quantitation of basal endogenous glucose production in Type II diabetes: importance of the volume of distribution. Diabetologia 45, 1053-1084.
-
(2002)
Diabetologia
, vol.45
, pp. 1053-1084
-
-
Radziuk, J.1
Pye, S.2
-
78
-
-
0025780748
-
Insulin resistance, but normal basal rates of glucose production in patients with newly diagnosed mild diabetes mellitus
-
Hother-Nielsen, O. and Beck-Nielsen, H. (1991) Insulin resistance, but normal basal rates of glucose production in patients with newly diagnosed mild diabetes mellitus. Acta Endocrinol Copenh 124, 637-645.
-
(1991)
Acta Endocrinol Copenh
, vol.124
, pp. 637-645
-
-
Hother-Nielsen, O.1
Beck-Nielsen, H.2
-
79
-
-
0025777471
-
Basal glucose metabolism in type 2 diabetes. A critical review
-
Hother-Nielsen, O. and Beck-Nielsen, H. (1991) Basal glucose metabolism in type 2 diabetes. A critical review. Diabet Metab 17, 136-145.
-
(1991)
Diabet Metab
, vol.17
, pp. 136-145
-
-
Hother-Nielsen, O.1
Beck-Nielsen, H.2
-
80
-
-
0030012782
-
Measurement of post-absorptive glucose kinetics in non-insulin-dependent diabetic patients: methodological aspects
-
Rigalleau, V., Beylot, M., Laville, M., Guillot, C., Deleris, G., Aubertin, J. and Gin, H. (1996) Measurement of post-absorptive glucose kinetics in non-insulin-dependent diabetic patients: methodological aspects. Eur J Clin Invest 26, 231-236.
-
(1996)
Eur J Clin Invest
, vol.26
, pp. 231-236
-
-
Rigalleau, V.1
Beylot, M.2
Laville, M.3
Guillot, C.4
Deleris, G.5
Aubertin, J.6
Gin, H.7
-
81
-
-
0028181010
-
Pathogenesis of type 2 (non-insulin-dependent) diabetes mellitus: the role of skeletal muscle glucose uptake and hepatic glucose production in the development of hyperglycaemia. A critical comment
-
Beck-Nielsen, H., Hother-Nielsen, O., Vaag, A. and Alford, F. (1994) Pathogenesis of type 2 (non-insulin-dependent) diabetes mellitus: the role of skeletal muscle glucose uptake and hepatic glucose production in the development of hyperglycaemia. A critical comment. Diabetologia 37, 217-221.
-
(1994)
Diabetologia
, vol.37
, pp. 217-221
-
-
Beck-Nielsen, H.1
Hother-Nielsen, O.2
Vaag, A.3
Alford, F.4
-
82
-
-
0036627887
-
Is hepatic glucose production increased in Type 2 diabetes mellitus?
-
Beck-Nielsen, H., Hother-Nielsen, O. and Staehr, P. (2002) Is hepatic glucose production increased in Type 2 diabetes mellitus? Curr Diabetes Rep 2 (3), 231-236.
-
(2002)
Curr Diabetes Rep
, vol.2
, Issue.3
, pp. 231-236
-
-
Beck-Nielsen, H.1
Hother-Nielsen, O.2
Staehr, P.3
-
83
-
-
0026786909
-
Banting Lecture: Glucose turnover. A key to understanding the pathogenesis of diabetes (indirect effects of insulin)
-
Vranic, M. (1992) Banting Lecture: Glucose turnover. A key to understanding the pathogenesis of diabetes (indirect effects of insulin). Diabetes 41, 1188-1206.
-
(1992)
Diabetes
, vol.41
, pp. 1188-1206
-
-
Vranic, M.1
-
84
-
-
0026443620
-
Importance of peripheral insulin levels for insulin-induced suppression of glucose production in depancreatized dogs
-
Giacca, A., Fisher, S. J., Shi, Z. Q., Gupta, R., Lickley, H. L. and Vranic, M. (1992) Importance of peripheral insulin levels for insulin-induced suppression of glucose production in depancreatized dogs. J Clin Invest 90, 1769-1777.
-
(1992)
J Clin Invest
, vol.90
, pp. 1769-1777
-
-
Giacca, A.1
Fisher, S.J.2
Shi, Z.Q.3
Gupta, R.4
Lickley, H.L.5
Vranic, M.6
-
85
-
-
0031851426
-
The direct and indirect effects of insulin on hepatic glucose production in vivo
-
Cherrington, A. D., Edgerton, D. and Sindelar, D. K. (1998) The direct and indirect effects of insulin on hepatic glucose production in vivo. Diabetologia 41, 987-996.
-
(1998)
Diabetologia
, vol.41
, pp. 987-996
-
-
Cherrington, A.D.1
Edgerton, D.2
Sindelar, D.K.3
-
86
-
-
0033126490
-
Banting Lecture 1997. Control of glucose uptake and release by the liver in vivo
-
Cherrington, A. D. (1999) Banting Lecture 1997. Control of glucose uptake and release by the liver in vivo. Diabetes 48, 1198-1214.
-
(1999)
Diabetes
, vol.48
, pp. 1198-1214
-
-
Cherrington, A.D.1
-
87
-
-
0029620621
-
Labelled glucose infusate technique in clamp studies. Is precise matching of glucose specific activity important?
-
Hother-Nielsen, O., Henriksen, J. E., Staehr, P. and Beck-Nielsen, H. (1995) Labelled glucose infusate technique in clamp studies. Is precise matching of glucose specific activity important? Endocrinol Metab 2, 275-287.
-
(1995)
Endocrinol Metab
, vol.2
, pp. 275-287
-
-
Hother-Nielsen, O.1
Henriksen, J.E.2
Staehr, P.3
Beck-Nielsen, H.4
-
88
-
-
0028847791
-
The effects of noninsulin-dependent diabetes mellitus on the kinetics of onset of insulin action in hepatic and extrahepatic tissues
-
Turk, D., Alzaid, A., Dinneen, S., Nair, K. S. and Rizza, R. (1995) The effects of noninsulin-dependent diabetes mellitus on the kinetics of onset of insulin action in hepatic and extrahepatic tissues. J Clin Invest 95, 755-762.
-
(1995)
J Clin Invest
, vol.95
, pp. 755-762
-
-
Turk, D.1
Alzaid, A.2
Dinneen, S.3
Nair, K.S.4
Rizza, R.5
-
89
-
-
0035434118
-
Small increases in insulin inhibit hepatic glucose production solely caused by an effect on glycogen metabolism
-
Edgerton, D. S., Cardin, S., Emshwiller, M., Neal, D., Chandramouli, V., Schumann, W. C., Landau, B. R., Rossetti, L. and Cherrington, A. D. (2001) Small increases in insulin inhibit hepatic glucose production solely caused by an effect on glycogen metabolism. Diabetes 50, 1872-1882.
-
(2001)
Diabetes
, vol.50
, pp. 1872-1882
-
-
Edgerton, D.S.1
Cardin, S.2
Emshwiller, M.3
Neal, D.4
Chandramouli, V.5
Schumann, W.C.6
Landau, B.R.7
Rossetti, L.8
Cherrington, A.D.9
-
90
-
-
0032972425
-
Resistance to insulin's acute direct hepatic effect in suppressing steady-state glucose production in individuals with type 2 diabetes
-
Lewis, G. F., Carpentier, A., Vranic, M. and Giacca, A. (1999) Resistance to insulin's acute direct hepatic effect in suppressing steady-state glucose production in individuals with type 2 diabetes. Diabetes 48, 570-576.
-
(1999)
Diabetes
, vol.48
, pp. 570-576
-
-
Lewis, G.F.1
Carpentier, A.2
Vranic, M.3
Giacca, A.4
-
91
-
-
0037317868
-
Effects of free fatty acids per se on glucose production, gluconeogenesis, and glycogenolysis
-
Staehr, P., Hother-Nielsen, O., Landau, B. R., Chandramouli, V., Holst, J. J. and Beck-Nielsen, H. (2003) Effects of free fatty acids per se on glucose production, gluconeogenesis, and glycogenolysis. Diabetes 52, 260-267.
-
(2003)
Diabetes
, vol.52
, pp. 260-267
-
-
Staehr, P.1
Hother-Nielsen, O.2
Landau, B.R.3
Chandramouli, V.4
Holst, J.J.5
Beck-Nielsen, H.6
-
92
-
-
0036293648
-
FFA cause hepatic insulin resistance by inhibiting insulin suppression of glycogenolysis
-
Boden, G., Cheung, P., Stein, T. P., Kresge, K. and Mozzoli, M. (2002) FFA cause hepatic insulin resistance by inhibiting insulin suppression of glycogenolysis. Am J Physiol Endocrinol Metab 283, E12-E19.
-
(2002)
Am J Physiol Endocrinol Metab
, vol.283
, pp. E12-E19
-
-
Boden, G.1
Cheung, P.2
Stein, T.P.3
Kresge, K.4
Mozzoli, M.5
-
93
-
-
0036737543
-
Glucagon dose-response curve for hepatic glucose production and glucose disposal in type 2 diabetic patients and normal individuals
-
Matsuda, M., DeFronzo, R. A., Glass, L., Consoli, A., Giordano, M., Bressler, P. and DelPrato, S. (2002) Glucagon dose-response curve for hepatic glucose production and glucose disposal in type 2 diabetic patients and normal individuals. Metabolism 51, 1111-1119.
-
(2002)
Metabolism
, vol.51
, pp. 1111-1119
-
-
Matsuda, M.1
DeFronzo, R.A.2
Glass, L.3
Consoli, A.4
Giordano, M.5
Bressler, P.6
DelPrato, S.7
-
94
-
-
0030815255
-
Assessment of hepatic sensitivity to glucagon in NIDDM: use as a tool to estimate the contribution of the indirect pathway to nocturnal glycogen synthesis
-
Nielsen, M. F., Wise, S., Dinneen, S. F., Schwenk, W. F., Basu, A. and Rizza, R. A. (1997) Assessment of hepatic sensitivity to glucagon in NIDDM: use as a tool to estimate the contribution of the indirect pathway to nocturnal glycogen synthesis. Diabetes 46, 2007-2016.
-
(1997)
Diabetes
, vol.46
, pp. 2007-2016
-
-
Nielsen, M.F.1
Wise, S.2
Dinneen, S.F.3
Schwenk, W.F.4
Basu, A.5
Rizza, R.A.6
-
95
-
-
0034524938
-
Lack of suppression of glucagon contributes to postprandial hyperglycemia in subjects with type 2 diabetes mellitus
-
Shah, P., Vella, A., Basu, A., Basu, R., Schwenk, W. F. and Rizza, R. A. (2000) Lack of suppression of glucagon contributes to postprandial hyperglycemia in subjects with type 2 diabetes mellitus. J Clin Endocrinol Metab 85, 4053-4059.
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 4053-4059
-
-
Shah, P.1
Vella, A.2
Basu, A.3
Basu, R.4
Schwenk, W.F.5
Rizza, R.A.6
-
96
-
-
0033890616
-
Influence of obesity and type 2 diabetes on gluconeogenesis and glucose output in humans: a quantitative study
-
Gastaldelli, A., Baldi, S., Pettiti, M., Toschi, E., Camastra, S., Natali, A., Landau, B. R. and Ferrannini, E. (2000) Influence of obesity and type 2 diabetes on gluconeogenesis and glucose output in humans: a quantitative study. Diabetes 49, 1367-1373.
-
(2000)
Diabetes
, vol.49
, pp. 1367-1373
-
-
Gastaldelli, A.1
Baldi, S.2
Pettiti, M.3
Toschi, E.4
Camastra, S.5
Natali, A.6
Landau, B.R.7
Ferrannini, E.8
-
97
-
-
0035430524
-
Effect of physiological hyperinsulinemia on gluconeogenesis in nondiabetic subjects and in type 2 diabetic patients
-
Gastaldelli, A., Toschi, E., Pettiti, M., Frascerra, S., Quinones-Galvan, A., Sironi, A. M., Natali, A. and Ferrannini, E. (2001) Effect of physiological hyperinsulinemia on gluconeogenesis in nondiabetic subjects and in type 2 diabetic patients. Diabetes 50, 1807-1812.
-
(2001)
Diabetes
, vol.50
, pp. 1807-1812
-
-
Gastaldelli, A.1
Toschi, E.2
Pettiti, M.3
Frascerra, S.4
Quinones-Galvan, A.5
Sironi, A.M.6
Natali, A.7
Ferrannini, E.8
-
98
-
-
0023928903
-
Mild type II diabetes markedly increases glucose cycling in the postabsorptive state and during glucose infusion irrespective of obesity
-
Efendic, S., Karlander, S. and Vranic, M. (1998) Mild type II diabetes markedly increases glucose cycling in the postabsorptive state and during glucose infusion irrespective of obesity. J Clin Invest 81, 1953-1961.
-
(1998)
J Clin Invest
, vol.81
, pp. 1953-1961
-
-
Efendic, S.1
Karlander, S.2
Vranic, M.3
-
99
-
-
0036515329
-
Hepatic insulin resistance in obese non-diabetic subjects and in type 2 diabetic patients
-
Paquot, N., Scheen, A. J., Dirlewanger, M., Lefebvre, P. J. and Tappy, L. (2002) Hepatic insulin resistance in obese non-diabetic subjects and in type 2 diabetic patients. Obes Res 10, 129-134.
-
(2002)
Obes Res
, vol.10
, pp. 129-134
-
-
Paquot, N.1
Scheen, A.J.2
Dirlewanger, M.3
Lefebvre, P.J.4
Tappy, L.5
-
100
-
-
0031031276
-
Induction of hepatic glucose-6-phosphatase gene expression by lipid infusion [published erratum appears in Diabetes 1997 Mar; 46 (3): 536]
-
Massillon, D., Barzilai, N., Hawkins, M., Prus-Wertheimer, D. and Rossetti, L. (1997) Induction of hepatic glucose-6-phosphatase gene expression by lipid infusion [published erratum appears in Diabetes 1997 Mar; 46 (3): 536]. Diabetes 46, 153-157.
-
(1997)
Diabetes
, vol.46
, pp. 153-157
-
-
Massillon, D.1
Barzilai, N.2
Hawkins, M.3
Prus-Wertheimer, D.4
Rossetti, L.5
-
101
-
-
0034034229
-
Glucose-6-phosphatase flux in vitro is increased in type 2 diabetes
-
Clore, J. N., Stillman, J. and Sugerman, H. (2000) Glucose-6-phosphatase flux in vitro is increased in type 2 diabetes. Diabetes 49, 969-974.
-
(2000)
Diabetes
, vol.49
, pp. 969-974
-
-
Clore, J.N.1
Stillman, J.2
Sugerman, H.3
-
102
-
-
0028967391
-
Liver glucokinase: decreased activity in patients with type II diabetes
-
Caro, J. F., Triester, S., Patel, V. K., Tapscott, E. B., Frazier, N. L. and Dohm, G. L. (1995) Liver glucokinase: decreased activity in patients with type II diabetes. Horm Metab Res 27, 19-22.
-
(1995)
Horm Metab Res
, vol.27
, pp. 19-22
-
-
Caro, J.F.1
Triester, S.2
Patel, V.K.3
Tapscott, E.B.4
Frazier, N.L.5
Dohm, G.L.6
-
103
-
-
0034800255
-
Mechanisms of hepatic very low-density lipoprotein overproduction in insulin resistance
-
Adeli, K., Taghibiglou, C., Van Iderstine, S. C. and Lewis, G. F. (2001) Mechanisms of hepatic very low-density lipoprotein overproduction in insulin resistance. Trends Cardiovasc Med 11, 170-176.
-
(2001)
Trends Cardiovasc Med
, vol.11
, pp. 170-176
-
-
Adeli, K.1
Taghibiglou, C.2
Van Iderstine, S.C.3
Lewis, G.F.4
-
104
-
-
0034708682
-
Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed hamster model
-
Taghibiglou, C., Carpentier, A., Van Iderstine, S. C., Chen, B., Rudy, D., Aiton, A., Lewis, G. F. and Adeli, K. (2000) Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed hamster model. J Biol Chem 275, 8416-8425.
-
(2000)
J Biol Chem
, vol.275
, pp. 8416-8425
-
-
Taghibiglou, C.1
Carpentier, A.2
Van Iderstine, S.C.3
Chen, B.4
Rudy, D.5
Aiton, A.6
Lewis, G.F.7
Adeli, K.8
-
105
-
-
0030986959
-
Defective regulation of triglyceride metabolism by insulin in the liver in NIDDM
-
Malmstrom, R., Packard, C. J., Caslake, M., Bedford, D., Stewart, P., Yki-Jarvinen, H., Shepherd, J. and Taskinen, M. R. (1997) Defective regulation of triglyceride metabolism by insulin in the liver in NIDDM. Diabetologia 40, 454-462.
-
(1997)
Diabetologia
, vol.40
, pp. 454-462
-
-
Malmstrom, R.1
Packard, C.J.2
Caslake, M.3
Bedford, D.4
Stewart, P.5
Yki-Jarvinen, H.6
Shepherd, J.7
Taskinen, M.R.8
-
106
-
-
0036217052
-
Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes
-
Lewis, G. F., Carpentier, A., Adeli, K. and Giacca, A. (2002) Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes. Endocr Rev 23, 201-229.
-
(2002)
Endocr Rev
, vol.23
, pp. 201-229
-
-
Lewis, G.F.1
Carpentier, A.2
Adeli, K.3
Giacca, A.4
|