-
1
-
-
0025064349
-
Effect of omeprazole treatment on diazepam plasma levels in slow versus normal rapid metabolizers of omeprazole
-
Andersson, T., Cederberg, C., Edvardsson, G., Heggelund, A., and Lundborg, P. 1990. Effect of omeprazole treatment on diazepam plasma levels in slow versus normal rapid metabolizers of omeprazole. Clin. Pharmacol. Ther. 47:79-85.
-
(1990)
Clin. Pharmacol. Ther.
, vol.47
, pp. 79-85
-
-
Andersson, T.1
Cederberg, C.2
Edvardsson, G.3
Heggelund, A.4
Lundborg, P.5
-
2
-
-
28844491802
-
Drug Metabolizing Enzymes-Evidence for Clinical Utility of Pharmacogenomic Tests
-
Andersson, T., Flockhart, D. A., Goldstein, D. B., Huang, S.-M., Kroetz, D. L., Milos, P. M., Ratain, M. J., and Thummel, K. 2005. Drug Metabolizing Enzymes-Evidence for Clinical Utility of Pharmacogenomic Tests. Clin. Pharmacol. Ther. 78(6):559-581.
-
(2005)
Clin. Pharmacol. Ther.
, vol.78
, Issue.6
, pp. 559-581
-
-
Andersson, T.1
Flockhart, D.A.2
Goldstein, D.B.3
Huang, S.-M.4
Kroetz, D.L.5
Milos, P.M.6
Ratain, M.J.7
Thummel, K.8
-
4
-
-
12244261584
-
Identification and functional characterization of new potentially defective alleles of human CYP2C19
-
Blaisdell, J., Mohrenweiser, H., Jackson, J., Ferguson, S., Coulter, S., Chanas, B., Xi, T., Ghanayem, B., and Goldstein, J. A. 2002. Identification and functional characterization of new potentially defective alleles of human CYP2C19. Pharmacogenetics 12:703-711.
-
(2002)
Pharmacogenetics
, vol.12
, pp. 703-711
-
-
Blaisdell, J.1
Mohrenweiser, H.2
Jackson, J.3
Ferguson, S.4
Coulter, S.5
Chanas, B.6
Xi, T.7
Ghanayem, B.8
Goldstein, J.A.9
-
5
-
-
2942627194
-
Pharmacogenetic study of statin therapy and cholesterol reduction
-
Chasman, D. I., Posada, D., Subrahmanyan, L., Cook, N. R., Stanton, V. P. Jr, and Ridker, P. M. 2004. Pharmacogenetic study of statin therapy and cholesterol reduction. JAMA 291:2821-2827.
-
(2004)
JAMA
, vol.291
, pp. 2821-2827
-
-
Chasman, D.I.1
Posada, D.2
Subrahmanyan, L.3
Cook, N.R.4
Stanton Jr., V.P.5
Ridker, P.M.6
-
6
-
-
0036750745
-
Postmarketing drug dosage changes of 499 PDA-approved new molecular entities, 1980-1999
-
Cross, J., Lee, H., Westelinck, A., Nelson, J., Grudzinskas, C., and Peck, C. 2002. Postmarketing drug dosage changes of 499 PDA-approved new molecular entities, 1980-1999. Pharmacoepidemiol Drug Saf. 11:439-446.
-
(2002)
Pharmacoepidemiol Drug Saf.
, vol.11
, pp. 439-446
-
-
Cross, J.1
Lee, H.2
Westelinck, A.3
Nelson, J.4
Grudzinskas, C.5
Peck, C.6
-
7
-
-
0035197548
-
Identification of variants of CYP3A4 and characterization of their abilities to metabolize testosterone and chlorpyrifos
-
Dai, D., Tang, J., Rose, R., Hodgson, E., Bienstock, R.J., Mohrenweiser, H.W., and Goldstein, J.A. 2001. Identification of variants of CYP3A4 and characterization of their abilities to metabolize testosterone and chlorpyrifos. J. Pharmacol. Exp. Ther. 299:825-831.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.299
, pp. 825-831
-
-
Dai, D.1
Tang, J.2
Rose, R.3
Hodgson, E.4
Bienstock, R.J.5
Mohrenweiser, H.W.6
Goldstein, J.A.7
-
8
-
-
84874757466
-
-
29 July, Arlington, VA. Washington, DC: U.S. Food and Drug Administration/Horsham, PA: Drug Information Association
-
DIA/FDA workshop: Co-Development of Drug, Biological and Device Products, 29 July 2004, Arlington, VA. Washington, DC: U.S. Food and Drug Administration/Horsham, PA: Drug Information Association. Available: http://www.diahome.org/Content/Events/04040.pdf [accessed August 31 2004].
-
(2004)
DIA/FDA Workshop: Co-Development of Drug, Biological and Device Products
-
-
-
9
-
-
0031746749
-
Same incidence of adverse drug events after codeine administration irrespective of the genetically determined differences in morphine formation
-
Eckhardt, K., Li, S., Ammon, S., Schanzle, G., Mikus, G., and Eichelbaum, M. 1998. Same incidence of adverse drug events after codeine administration irrespective of the genetically determined differences in morphine formation. Pain 76:27-33.
-
(1998)
Pain
, vol.76
, pp. 27-33
-
-
Eckhardt, K.1
Li, S.2
Ammon, S.3
Schanzle, G.4
Mikus, G.5
Eichelbaum, M.6
-
10
-
-
0033569516
-
Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics
-
Evans, W. E., and Relling, M. V. 1999. Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics. Science 286:487-491.
-
(1999)
Science
, vol.286
, pp. 487-491
-
-
Evans, W.E.1
Relling, M.V.2
-
11
-
-
0035871560
-
Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine
-
Evans, W. E., Hon, Y. Y., Bomgaars, L., Coutre, S., Holdsworth, M., Janco, R., Kalwinsky, D., Keller, F., Khatib, Z., Margolin, J., Murray, J., Quinn, J., Ravindranath, Y., Ritchey, K., Roberts, W., Rogers, Z. R., Schiff, D., Steuber, C., Tucci, F., Kornegay, N., Krynetski, E. Y., and Relling, M. 2001. Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine. J. Clin. Oncol. 19:2293-2301.
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 2293-2301
-
-
Evans, W.E.1
Hon, Y.Y.2
Bomgaars, L.3
Coutre, S.4
Holdsworth, M.5
Janco, R.6
Kalwinsky, D.7
Keller, F.8
Khatib, Z.9
Margolin, J.10
Murray, J.11
Quinn, J.12
Ravindranath, Y.13
Ritchey, K.14
Roberts, W.15
Rogers, Z.R.16
Schiff, D.17
Steuber, C.18
Tucci, F.19
Kornegay, N.20
Krynetski, E.Y.21
Relling, M.22
more..
-
12
-
-
0037421590
-
Pharmacogenomics-drug disposition, drug targets, and side effects
-
Evans, W. E., and McLeod, H. L. 2003. Pharmacogenomics-drug disposition, drug targets, and side effects. N. Engl. J. Med. 348:538-549.
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 538-549
-
-
Evans, W.E.1
McLeod, H.L.2
-
13
-
-
2642570170
-
Moving towards individualized medicine with pharmacogenomics
-
Evans, W. E., and Relling, M. V. 2004. Moving towards individualized medicine with pharmacogenomics. Nature 429:464-468.
-
(2004)
Nature
, vol.429
, pp. 464-468
-
-
Evans, W.E.1
Relling, M.V.2
-
14
-
-
4344579337
-
Pharmacogenetics of thiopurine S-methyltransferase and thiopurine therapy
-
Evans, W. E. 2004. Pharmacogenetics of thiopurine S-methyltransferase and thiopurine therapy. Ther. Drug. Monit. 26:186-191.
-
(2004)
Ther. Drug. Monit.
, vol.26
, pp. 186-191
-
-
Evans, W.E.1
-
17
-
-
84874757033
-
-
labeling recommendations: http://www.fda. gov/ohrms/dockets/ac/05/ briefing/2005-4194B1 03 Topic-1A.pdf; http:// www.fda.gov/ohrms/dockets/ac/05/ slides/2005-4194S1 Slide-Index.htm; http://www.fda.gov/ohrms/dockets/ac/05/ slides/2005-4194S1 02 01-Huang. ppt
-
FDA Advisory Committee for Pharmaceutical Sciences; Clinical Pharmacology Subcommittee meeting 2005, http://www.fda.gov/ohrms/dockets/ac/ cder05.html#PharmScience; labeling recommendations: http://www.fda. gov/ohrms/dockets/ac/05/briefing/2005-4194B1 03 Topic-1A.pdf; http:// www.fda.gov/ohrms/dockets/ac/05/slides/2005-4194S1 Slide-Index.htm; http://www.fda.gov/ohrms/dockets/ac/05/slides/2005-4194S1 02 01-Huang. ppt
-
(2005)
FDA Advisory Committee for Pharmaceutical Sciences; Clinical Pharmacology Subcommittee Meeting
-
-
-
19
-
-
4444291376
-
-
FDA Mission Statement. 2004: http://www.fda.gov/opacom/morechoices/ mmission.html [accessed September 4, 2004].
-
(2004)
FDA Mission Statement
-
-
-
20
-
-
84874757198
-
Innovation or Stagnation, challenge and opportunity on the critical path to new medical products
-
FDA whitepaper, 2004. Innovation or Stagnation, challenge and opportunity on the critical path to new medical products: http://www.fda.gov/oc/ initiatives/criticalpath/whitepaper.html [accessed September 4 2004].
-
(2004)
FDA Whitepaper
-
-
-
23
-
-
57749184276
-
-
http://www.fda.gov/cder/approval/index.htm or Physicians' Desk Reference at http://pdrel.thomsonhc.com/pdrel/librarian
-
FDA Labeling information from: http://www.accessdata.fda.gov/scripts/ cder/ drugsatfda, http://www.fda.gov/cder/approval/index.htm or Physicians' Desk Reference at http://pdrel.thomsonhc.com/pdrel/librarian.
-
FDA Labeling Information
-
-
-
24
-
-
84874756481
-
-
FDA Purinenthol labeling: http://www.fda.gov/cder/foi/label/2004/ 09053s0241bl. pdf [last accessed September 18, 2004].
-
FDA Purinenthol Labeling
-
-
-
30
-
-
84874757677
-
-
September 13-14, Rockville, MD
-
FDA workshop: FDA/PhRMA/JHU educational workshop, September 13-14, 2004, Rockville, MD: http://www.fda.gov/cder/offices/ocpb/workshops.htm [accessed June 2, 2005].
-
(2004)
FDA Workshop: FDA/PhRMA/JHU Educational Workshop
-
-
-
31
-
-
33645006219
-
FR notice 2000: Labeling guideline
-
December 22
-
FR notice 2000: Labeling guideline (Federal Register 65: 247; 81082-81131; December 22, 2000).
-
(2000)
Federal Register
, vol.65
, pp. 247
-
-
-
32
-
-
0037022006
-
Swiss HIV Cohort Study, Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: A pharmacogenetics study
-
Fellay, J., Marzolini, C., Meaden, E. R., Back, D. J., Buclin, T., Chave, J. P., Decosterd, L. A., Furrer, H., Opravil, M., Pantaleo, G., Retelska, D., Ruiz, L., Schinkel, A. H., Vernazza, P., Eap, C. B., and Telenti, A. 2002. Swiss HIV Cohort Study, Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: A pharmacogenetics study. Lancet. 359:30-36.
-
(2002)
Lancet
, vol.359
, pp. 30-36
-
-
Fellay, J.1
Marzolini, C.2
Meaden, E.R.3
Back, D.J.4
Buclin, T.5
Chave, J.P.6
Decosterd, L.A.7
Furrer, H.8
Opravil, M.9
Pantaleo, G.10
Retelska, D.11
Ruiz, L.12
Schinkel, A.H.13
Vernazza, P.14
Eap, C.B.15
Telenti, A.16
-
34
-
-
4444297550
-
112-12 Editorial: Regulatory acceptance of toxicogenomics data
-
Frueh, F. W., Huang, S.-M., and Lesko, L. J. 2004. 112-12 editorial: Regulatory acceptance of toxicogenomics data. Environ. Health Perspect. 112:A663-A664.
-
(2004)
Environ. Health Perspect.
, vol.112
-
-
Frueh, F.W.1
Huang, S.-M.2
Lesko, L.J.3
-
35
-
-
23644446653
-
The Need for Education in Pharmacogenomics: A regulatory perspective
-
Frueh, F. W., Goodsaid, F., Rudman, A., Huang, S.-M., and Lesko, L. J. 2005. The Need for Education in Pharmacogenomics: A regulatory perspective. Pharmacogenomics J. 5:218-220.
-
(2005)
Pharmacogenomics J.
, vol.5
, pp. 218-220
-
-
Frueh, F.W.1
Goodsaid, F.2
Rudman, A.3
Huang, S.-M.4
Lesko, L.J.5
-
36
-
-
2442593964
-
Impact of CYP2D6 intermediate metabolizer alleles on single-dose desipramine pharmacokinetics
-
Furman, K. D., Grimm, D. R., Mueller, T., Holley-Shanks, R. R., Bertz, R. J., Williams, L. A., Spear, B. B., and Katz, D. A. 2004. Impact of CYP2D6 intermediate metabolizer alleles on single-dose desipramine pharmacokinetics. Pharmacogenetics 14:279-284.
-
(2004)
Pharmacogenetics
, vol.14
, pp. 279-284
-
-
Furman, K.D.1
Grimm, D.R.2
Mueller, T.3
Holley-Shanks, R.R.4
Bertz, R.J.5
Williams, L.A.6
Spear, B.B.7
Katz, D.A.8
-
37
-
-
1542394539
-
Pharmacogenomics of proton pump inhibitors
-
Furuta, T., Shirai, N., Sugimoto, M., Ohashi, K., Ishizaki, T. 2004. Pharmacogenomics of proton pump inhibitors. Pharmacogenomics 5:181-202.
-
(2004)
Pharmacogenomics
, vol.5
, pp. 181-202
-
-
Furuta, T.1
Shirai, N.2
Sugimoto, M.3
Ohashi, K.4
Ishizaki, T.5
-
38
-
-
0036339071
-
Unique CYP2D6 activity distribution and genotype-phenotype discordance in black Americans
-
Gaedigk, A., Bradford, L. D., Marcucci, K. A., Leeder, J. S. 2002. Unique CYP2D6 activity distribution and genotype-phenotype discordance in black Americans. Clin. Pharmacol. Ther. 72:76-89.
-
(2002)
Clin. Pharmacol. Ther.
, vol.72
, pp. 76-89
-
-
Gaedigk, A.1
Bradford, L.D.2
Marcucci, K.A.3
Leeder, J.S.4
-
39
-
-
84874756737
-
-
ed., Steven H. Y. Wong, Mark Linder, Roland Valdes, AACC Press (in press)
-
Goodsaid, F., Huang, S.-M., Frueh, F., Temple, R., and Lesko, L. J. Regulatory Guidance and Application of Genomic Biomarkers in Drug Development in "Principles of Clinical Pharmacogenomics," ed., Steven H. Y. Wong, Mark Linder, Roland Valdes, AACC Press (in press).
-
Regulatory Guidance and Application of Genomic Biomarkers in Drug Development in "Principles of Clinical Pharmacogenomics,"
-
-
Goodsaid, F.1
Huang, S.-M.2
Frueh, F.3
Temple, R.4
Lesko, L.J.5
-
40
-
-
0034074170
-
Significant interaction between the nonprescription antihistamine diphenhydramine and the CYP2D6 substrate metoprolol in healthy men with high or low CYP2D6 activity
-
Hamelin, B. A., Bouayad, A., Methot, J., Jobin, J., Desgagnes, P., Poirier, P., Allaire, J., Dumesnil, J., and Turgeon, J. 2000. Significant interaction between the nonprescription antihistamine diphenhydramine and the CYP2D6 substrate metoprolol in healthy men with high or low CYP2D6 activity. Clin. Pharmacol. Ther. 67:466-177.
-
(2000)
Clin. Pharmacol. Ther.
, vol.67
, pp. 466-1177
-
-
Hamelin, B.A.1
Bouayad, A.2
Methot, J.3
Jobin, J.4
Desgagnes, P.5
Poirier, P.6
Allaire, J.7
Dumesnil, J.8
Turgeon, J.9
-
41
-
-
12144286933
-
The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patients
-
Haufroid, V., Mourad, M., Van Kerckhove, V., Wawrzyniak, J., De Meyer, M., Eddour, D. C., Malaise, J., Lison, D., Squifflet, J. P., and Wallemacq, P. 2004. The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patients. Pharmacogenetics 14:147-154.
-
(2004)
Pharmacogenetics
, vol.14
, pp. 147-154
-
-
Haufroid, V.1
Mourad, M.2
Van Kerckhove, V.3
Wawrzyniak, J.4
De Meyer, M.5
Eddour, D.C.6
Malaise, J.7
Lison, D.8
Squifflet, J.P.9
Wallemacq, P.10
-
42
-
-
0037197044
-
Genetic variations in HLA-B region andhypersensitivity reactions to abacavir
-
Hetherington, S., Hughes, A. R., Mosteller, M., Shortino, D., Baker, K. L., Spreen, W., Lai, E., Davies, K., Handley, A., Dow, D. J., Fling, M. E., Stocum, M., Bowman, C., Thurmond, L. M., and Roses, A. D. 2002. Genetic variations in HLA-B region andhypersensitivity reactions to abacavir. Lancet 359:1121-1122.
-
(2002)
Lancet
, vol.359
, pp. 1121-1122
-
-
Hetherington, S.1
Hughes, A.R.2
Mosteller, M.3
Shortino, D.4
Baker, K.L.5
Spreen, W.6
Lai, E.7
Davies, K.8
Handley, A.9
Dow, D.J.10
Fling, M.E.11
Stocum, M.12
Bowman, C.13
Thurmond, L.M.14
Roses, A.D.15
-
43
-
-
0037012465
-
Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy
-
Higashi, M. K., Veenstra, D. L., Kondo, L. M., et al. 2002. Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy. JAMA 287:1690-1698.
-
(2002)
JAMA
, vol.287
, pp. 1690-1698
-
-
Higashi, M.K.1
Veenstra, D.L.2
Kondo, L.M.3
-
44
-
-
4143065736
-
Relative impact of covariates in prescribing warfarin according to CYP2C9 genotype
-
HIll, M. A., Wilke, R. A., Caldwell, M. D., Berg, R. L., Glurich, I., and Burmester, J. K. 2004. Relative impact of covariates in prescribing warfarin according to CYP2C9 genotype. Pharmacogenetics 4:539-547.
-
(2004)
Pharmacogenetics
, vol.4
, pp. 539-547
-
-
Hill, M.A.1
Wilke, R.A.2
Caldwell, M.D.3
Berg, R.L.4
Glurich, I.5
Burmester, J.K.6
-
45
-
-
0034724324
-
Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
-
Hoffmeyer, S., Burk, O., von Richter, O., Arnold, H. P., Brockmoller, J., Johne, A., Cascorbi, I., Gerloff, T., Roots, I., Eichelbaum, M., Brinkmann, U. 2000. Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc. Natl. Acad. Sci. USA 97:3473-3478.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
Von Richter, O.3
Arnold, H.P.4
Brockmoller, J.5
Johne, A.6
Cascorbi, I.7
Gerloff, T.8
Roots, I.9
Eichelbaum, M.10
Brinkmann, U.11
-
46
-
-
84902056013
-
Evaluation of Drugs in Women: Regulatory Perspective - In Section 11, Drug Metabolism/Clinical pharmacology (section editor: Schwartz, J)
-
Ed., Legato M, Academic Press
-
Huang, S.-M., Miller, M., Toigo, T., Chen, M., Sahajwalla, C., Lesko, L. J., and Temple, R. 2004. Evaluation of Drugs in Women: Regulatory Perspective - in Section 11, Drug Metabolism/Clinical pharmacology (section editor: Schwartz, J), pp. 848-859, in "Principles of Gender-Specific Medicine," Ed., Legato M, Academic Press.
-
(2004)
Principles of Gender-Specific Medicine
, pp. 848-859
-
-
Huang, S.-M.1
Miller, M.2
Toigo, T.3
Chen, M.4
Sahajwalla, C.5
Lesko, L.J.6
Temple, R.7
-
47
-
-
2442700486
-
Drug-drug, drug-dietary supplement and drug-citrus fruit and other food interactions- what have we learned?
-
Huang, S.-M., and Lesko, L. J. 2004. Drug-drug, drug-dietary supplement and drug-citrus fruit and other food interactions- what have we learned? J. Clin. Pharmacol. 44:559-569.
-
(2004)
J. Clin. Pharmacol.
, vol.44
, pp. 559-569
-
-
Huang, S.-M.1
Lesko, L.J.2
-
48
-
-
84874756973
-
-
September 13-14, Rockville, MD
-
Huang, S.-M. "Regulatory issues in genotyping metabolizing enzymes- CDER Perspective", presentation at the FDA/PhRMA/JHU educational workshop, September 13-14, 2004, Rockville, MD: http://www.fda.gov/cder/offices/ ocpb/workshops.htm [accessed June 2, 2005].
-
(2004)
"Regulatory Issues in Genotyping Metabolizing Enzymes- CDER Perspective", Presentation at the FDA/PhRMA/JHU Educational Workshop
-
-
Huang, S.-M.1
-
49
-
-
33644991861
-
Application of Pharmacogenomics in Clinical Pharmacology - In Volume I: Molecular Medicine, Correlation between genes, diseases and biopharmaceuticals
-
Ed., Jorg Knablein and RH Muller, Wiley, VCH
-
Huang, S.-M., and Lesko, L. J. 2005. Application of Pharmacogenomics in Clinical Pharmacology - in Volume I: Molecular Medicine, Correlation between genes, diseases and biopharmaceuticals, in "Modern Biopharmaceuticals- Design, Development and Optimization", Ed., Jorg Knablein and RH Muller, Wiley, VCH, pages 49-70.
-
(2005)
Modern Biopharmaceuticals- Design, Development and Optimization
, pp. 49-70
-
-
Huang, S.-M.1
Lesko, L.J.2
-
51
-
-
4444237870
-
-
ICH E5, E5 Questions and Answers (2004) http://www.fda.gov/cder/guidance/ 6200fnl.pdf
-
ICH E5 1998. Guidance on Ethnic Factors in the Acceptability of Foreign Clinical Data: http://www.fda.gov/cder/guidance/index.htm, E5 Questions and Answers (2004) http://www.fda.gov/cder/guidance/6200fnl.pdf [accessed September 4, 2004].
-
(1998)
Guidance on Ethnic Factors in the Acceptability of Foreign Clinical Data
-
-
-
52
-
-
2342459714
-
Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan
-
Epub 2004 Mar 08
-
Innocenti, F., Undevia, S. D., Iyer, L., Chen, P. X., Das, S., Kocherginsky, M., Karrison, T., Janisch, L., Ramirez, J., Rudin, C. M., Vokes, E. E., and Ratain, M. J. 2004. Genetic variants in the UDP- glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan. J. Clin. Oncol. 22:1382-1388. Epub 2004 Mar 08.
-
(2004)
J. Clin. Oncol.
, vol.22
, pp. 1382-1388
-
-
Innocenti, F.1
Undevia, S.D.2
Iyer, L.3
Chen, P.X.4
Das, S.5
Kocherginsky, M.6
Karrison, T.7
Janisch, L.8
Ramirez, J.9
Rudin, C.M.10
Vokes, E.E.11
Ratain, M.J.12
-
53
-
-
0035052741
-
National Heart, Lung, and Blood Institute's Asthma Clinical Research Network, Effect of polymorphism of the beta(2)-adrenergic receptor on response to regular use of albuterol in asthma
-
Israel, E., Drazen, J. M., Liggett, S. B., Boushey, H. A., Cherniack, R. M., Chinchilli, V. M., Cooper, D. M., Fahy, J. V., Fish, J. E., Ford, J. G., Kraft, M., Kunselman, S., Lazarus, S. C., Lemanske, R. F. Jr, Martin, R. J., McLean, D. E., Peters, S. P., Silverman, E. K., Sorkness, C. A., Szefler, S. J., Weiss, S. T., and Yandava, C. N. 2001. National Heart, Lung, and Blood Institute's Asthma Clinical Research Network, Effect of polymorphism of the beta(2)-adrenergic receptor on response to regular use of albuterol in asthma. Int. J. Arch. Allergy Immunol. 124:183-186.
-
(2001)
Int. J. Arch. Allergy Immunol.
, vol.124
, pp. 183-186
-
-
Israel, E.1
Drazen, J.M.2
Liggett, S.B.3
Boushey, H.A.4
Cherniack, R.M.5
Chinchilli, V.M.6
Cooper, D.M.7
Fahy, J.V.8
Fish, J.E.9
Ford, J.G.10
Kraft, M.11
Kunselman, S.12
Lazarus, S.C.13
Lemanske Jr., R.F.14
Martin, R.J.15
McLean, D.E.16
Peters, S.P.17
Silverman, E.K.18
Sorkness, C.A.19
Szefler, S.J.20
Weiss, S.T.21
Yandava, C.N.22
more..
-
54
-
-
0036025450
-
UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity
-
Iyer, L., Das, S., Janisch, L., Wen, M., Ramirez, J., Karrison, T., Fleming, G. F., Vokes, E. E., Schilsky, R. L., and Ratain, M. J. 2002. UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity. Pharmacogenomics J. 2:43-47.
-
(2002)
Pharmacogenomics J.
, vol.2
, pp. 43-47
-
-
Iyer, L.1
Das, S.2
Janisch, L.3
Wen, M.4
Ramirez, J.5
Karrison, T.6
Fleming, G.F.7
Vokes, E.E.8
Schilsky, R.L.9
Ratain, M.J.10
-
55
-
-
3042772026
-
Identification of functionally variant MDR1 alleles among European Americans and African Americans
-
Kim, R. B., Leake, B. F., Choo, E. F., Dresser, G. K., Kubba, S. V., Schwarz, U. I., Taylor, A., Xie, H. G., McKinsey, J., Zhou, S., Lan, L. B., Schuetz, J. D., Schuetz, E. G., and Wilkinson, G. R. 2001. Identification of functionally variant MDR1 alleles among European Americans and African Americans. Clin. Pharmacol. Ther. 70:189-199.
-
(2001)
Clin. Pharmacol. Ther.
, vol.70
, pp. 189-199
-
-
Kim, R.B.1
Leake, B.F.2
Choo, E.F.3
Dresser, G.K.4
Kubba, S.V.5
Schwarz, U.I.6
Taylor, A.7
Xie, H.G.8
McKinsey, J.9
Zhou, S.10
Lan, L.B.11
Schuetz, J.D.12
Schuetz, E.G.13
Wilkinson, G.R.14
-
56
-
-
0032522873
-
Incidence of Adverse Drug Reactions in Hospitalized Patients, A Meta-analysis of Prospective Studies
-
Lazarou, J., Pomeranz, B. H., and Corey, P. N. 1998. Incidence of Adverse Drug Reactions in Hospitalized Patients, A Meta-analysis of Prospective Studies. JAMA 279:1200-1205.
-
(1998)
JAMA
, vol.279
, pp. 1200-1205
-
-
Lazarou, J.1
Pomeranz, B.H.2
Corey, P.N.3
-
57
-
-
0037380651
-
Pharmacogenetics and pharmacogenomics in drug development and regulatory decision making: Report of the first FDA-PWG-PhRMA-DruSafe Workshop
-
Lesko, L. J., Salerno, R. A., Spear, B. B., Anderson, D. C., Anderson, T., Brazell, C., Collins, J., Dorner, A., Essayan, D., Gomez-Mancilla, B., Hackett. J., Huang. S. M., Ide, S., Killinger, J., Leighton, J., Mansfield, E., Meyer, R., Ryan, S. G., Schmith, V., Shaw, P., Sistare, F., Watson, M., Worobec, A. 2003. Pharmacogenetics and pharmacogenomics in drug development and regulatory decision making: report of the first FDA-PWG-PhRMA-DruSafe Workshop. J Clin. Pharmacol. 43:342-358.
-
(2003)
J Clin. Pharmacol.
, vol.43
, pp. 342-358
-
-
Lesko, L.J.1
Salerno, R.A.2
Spear, B.B.3
Anderson, D.C.4
Anderson, T.5
Brazell, C.6
Collins, J.7
Dorner, A.8
Essayan, D.9
Gomez-Mancilla, B.10
Hackett, J.11
Huang, S.M.12
Ide, S.13
Killinger, J.14
Leighton, J.15
Mansfield, E.16
Meyer, R.17
Ryan, S.G.18
Schmith, V.19
Shaw, P.20
Sistare, F.21
Watson, M.22
Worobec, A.23
more..
-
58
-
-
3543063976
-
Pharmacogenomic data submissions to the FDA: Non-clinical case studies
-
Leighton, J. K., DeGeorge, J., Jacobson-Kram, D., MacGregor, J., Mendrick, D., Worobec, A. 2004. Pharmacogenomic data submissions to the FDA: non-clinical case studies. Pharmacogenomics 5:507-511.
-
(2004)
Pharmacogenomics
, vol.5
, pp. 507-511
-
-
Leighton, J.K.1
DeGeorge, J.2
Jacobson-Kram, D.3
MacGregor, J.4
Mendrick, D.5
Worobec, A.6
-
59
-
-
4544335467
-
Translation of pharmacogenomics and pharmacogenetics: A regulatory perspective
-
Lesko, L. J., and Woodcock, J. 2004. Translation of pharmacogenomics and pharmacogenetics: A regulatory perspective. Nat. Rev. Drug Discov. 3:763-769.
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, pp. 763-769
-
-
Lesko, L.J.1
Woodcock, J.2
-
60
-
-
2342562985
-
Cytochrome P-450 2D6* 10 C188T polymorphism is associated with antipsychotic-induced persistent tardive dyskinesia in Chinese schizophrenic patients
-
Liou, Y. J., Wang, Y. C., Bai, Y. M., Lin, C. C., Yu, S. C., Liao, D. L., Lin, M. W., Chen, J. Y. and Lai, I. C. 2004. Cytochrome P-450 2D6* 10 C188T polymorphism is associated with antipsychotic-induced persistent tardive dyskinesia in Chinese schizophrenic patients. Neuropsychobiology 49:167-173.
-
(2004)
Neuropsychobiology
, vol.49
, pp. 167-173
-
-
Liou, Y.J.1
Wang, Y.C.2
Bai, Y.M.3
Lin, C.C.4
Yu, S.C.5
Liao, D.L.6
Lin, M.W.7
Chen, J.Y.8
Lai, I.C.9
-
61
-
-
12144287977
-
Association between polymorphism in IgG Fc receptor IIIa coding gene and biological response to infliximab in Crohn's disease
-
Louis, E., El Ghoul, Z., Vermeire, S., Dall'Ozzo, S., Rutgeerts, P., Paintaud, G., Belaiche, J., De Vos, M., Van Gossum, A., Colombel, J. F., and Watier, H. 2004. Association between polymorphism in IgG Fc receptor IIIa coding gene and biological response to infliximab in Crohn's disease. Aliment. Pharmacol. Ther. 19:511-519.
-
(2004)
Aliment. Pharmacol. Ther.
, vol.19
, pp. 511-519
-
-
Louis, E.1
El Ghoul, Z.2
Vermeire, S.3
Dall'Ozzo, S.4
Rutgeerts, P.5
Paintaud, G.6
Belaiche, J.7
De Vos, M.8
Van Gossum, A.9
Colombel, J.F.10
Watier, H.11
-
62
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Epub 2004 Apr 29
-
Lynch, T. J., Bell, D. W., Sordella, R., Gurubhagavatula, S., Okimoto, R. A., Brannigan, B. W., Harris, P. L., Haserlat, S. M., Supko, J. G., Haluska, F. G., Louis, D. N., Christiani, D. C., Settleman, J., and Haber, D. A. 2004. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N. Engl. J. Med. 350:2129-2139. Epub 2004 Apr 29.
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
Brannigan, B.W.6
Harris, P.L.7
Haserlat, S.M.8
Supko, J.G.9
Haluska, F.G.10
Louis, D.N.11
Christiani, D.C.12
Settleman, J.13
Haber, D.A.14
-
64
-
-
0034034158
-
Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia
-
McLeod, H. L., Krynetski, E. Y., Relling, M. V., and Evans, W. E. 2000. Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia. Leukemia. 14:567-572.
-
(2000)
Leukemia
, vol.14
, pp. 567-572
-
-
McLeod, H.L.1
Krynetski, E.Y.2
Relling, M.V.3
Evans, W.E.4
-
65
-
-
0141706934
-
Polymorphism in CYP2C8 is associated with reduced plasma concentrations of repaglinide
-
Niemi, M., Leathart, J. B., Neuvonen, M., Backman, J. T., Daly, A. K., and Neuvonen, P. J. 2003. Polymorphism in CYP2C8 is associated with reduced plasma concentrations of repaglinide. Clin. Pharmacol. Ther. 74:380-387.
-
(2003)
Clin. Pharmacol. Ther.
, vol.74
, pp. 380-387
-
-
Niemi, M.1
Leathart, J.B.2
Neuvonen, M.3
Backman, J.T.4
Daly, A.K.5
Neuvonen, P.J.6
-
66
-
-
0038209381
-
Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: Consequences for pravastatin pharmacokinetics
-
Nishizato, Y., Ieiri, I., Suzuki, H., Kimura, M., Kawabata, K., Hirota, T., Takane, H., Irie, S., Kusuhara, H., Urasaki, Y., Urae, A., Higuchi, S., Otsubo, K., and Sugiyama, Y. 2003. Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: Consequences for pravastatin pharmacokinetics. Clin. Pharmacol. Ther. 73:554-565.
-
(2003)
Clin. Pharmacol. Ther.
, vol.73
, pp. 554-565
-
-
Nishizato, Y.1
Ieiri, I.2
Suzuki, H.3
Kimura, M.4
Kawabata, K.5
Hirota, T.6
Takane, H.7
Irie, S.8
Kusuhara, H.9
Urasaki, Y.10
Urae, A.11
Higuchi, S.12
Otsubo, K.13
Sugiyama, Y.14
-
67
-
-
12644291917
-
Human thiopurine methyltransferase pharmacogenetics: Gene sequence polymorphisms
-
Otterness, D., Szumlanski, C., Lennard, L., Klemetsdal, B., Aarbakke, J., Park-Hah, J. O., Iven, H., Schmiegelow, K., Branum, E., O'Brien, J., and Weinshilboum, R. 1997. Human thiopurine methyltransferase pharmacogenetics: Gene sequence polymorphisms. Clin. Pharmacol. Ther. 62:60-73.
-
(1997)
Clin. Pharmacol. Ther.
, vol.62
, pp. 60-73
-
-
Otterness, D.1
Szumlanski, C.2
Lennard, L.3
Klemetsdal, B.4
Aarbakke, J.5
Park-Hah, J.O.6
Iven, H.7
Schmiegelow, K.8
Branum, E.9
O'Brien, J.10
Weinshilboum, R.11
-
68
-
-
4544387969
-
Association of long QT syndrome loci and cardiac events among patients treated with beta-blockers
-
Priori, S. G., Napolitano, C., Schwartz, P. J., Grillo, M., Bloise, R., Ronchetti, E., Moncalvo, C., Tulipani, C., Veia, A., Bottelli, G., and Nastoli, J. 2004. Association of long QT syndrome loci and cardiac events among patients treated with beta-blockers. JAMA 292:1341-1344.
-
(2004)
JAMA
, vol.292
, pp. 1341-1344
-
-
Priori, S.G.1
Napolitano, C.2
Schwartz, P.J.3
Grillo, M.4
Bloise, R.5
Ronchetti, E.6
Moncalvo, C.7
Tulipani, C.8
Veia, A.9
Bottelli, G.10
Nastoli, J.11
-
69
-
-
0035861049
-
Potential Role of Pharmacogenomics in Reducing Adverse Drug Reactions: A Systematic Review
-
Phillips, K. A., Veenstra, D. L., Oren, E., Lee, J. K., Sadee, W. 2001. Potential Role of Pharmacogenomics in Reducing Adverse Drug Reactions: A Systematic Review. JAMA 286:2270-2279.
-
(2001)
JAMA
, vol.286
, pp. 2270-2279
-
-
Phillips, K.A.1
Veenstra, D.L.2
Oren, E.3
Lee, J.K.4
Sadee, W.5
-
70
-
-
3042767682
-
Functional implications of genetic polymorphisms in the multidrug resistance gene MDR1 (ABCB1)
-
Pauli-Magnus, C., and Kroetz, D. L. 2004. Functional implications of genetic polymorphisms in the multidrug resistance gene MDR1 (ABCB1). Pharm. Res. 21:904-913.
-
(2004)
Pharm. Res.
, vol.21
, pp. 904-913
-
-
Pauli-Magnus, C.1
Kroetz, D.L.2
-
71
-
-
1542346407
-
CYP2C9 genotypes and dose requirements during the induction phase of oral anticoagulant therapy
-
Peyvandi, F., Spreafico, M., Siboni, S. M., Moia, M., and Mannucci, P. M. 2004. CYP2C9 genotypes and dose requirements during the induction phase of oral anticoagulant therapy. Clin. Pharmacol. Ther. 75:198-203.
-
(2004)
Clin. Pharmacol. Ther.
, vol.75
, pp. 198-203
-
-
Peyvandi, F.1
Spreafico, M.2
Siboni, S.M.3
Moia, M.4
Mannucci, P.M.5
-
73
-
-
4143101374
-
Relevance of different UGT1A1 polymorphisms in irinotecan-induced toxicity: A molecular and clinical study of 75 patients
-
Rouits, E., Boisdron-Celle, M., Dumont, A., Guerin, O., Morel, A., and Gamelin, E. 2004. Relevance of different UGT1A1 polymorphisms in irinotecan-induced toxicity: A molecular and clinical study of 75 patients. Clin. Cancer Res. 10:5151-5159.
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 5151-5159
-
-
Rouits, E.1
Boisdron-Celle, M.2
Dumont, A.3
Guerin, O.4
Morel, A.5
Gamelin, E.6
-
74
-
-
3543080360
-
Pharmacogenomic data submissions to the FDA: Clinical pharmacology case studies
-
Ruaño, G., Collins, J. M., Dorner, A. J., Wang, S.-J., Guerciolini, R., and Huang, S.-M. 2004. Pharmacogenomic data submissions to the FDA: Clinical pharmacology case studies. Pharmacogenomics 5: 513-517.
-
(2004)
Pharmacogenomics
, vol.5
, pp. 513-517
-
-
Ruaño, G.1
Collins, J.M.2
Dorner, A.J.3
Wang, S.-J.4
Guerciolini, R.5
Huang, S.-M.6
-
75
-
-
84874757714
-
-
July 12, 2003: abstract in 52nd Annual American College of Cardiology (Scientific Session) March 30-April 2, Chicago, IL
-
Ruano, G., et al. XIV International Symposium on Drugs Affecting Lipid Metabolism, July 12, 2003: abstract in 52nd Annual American College of Cardiology (Scientific Session) March 30-April 2, 2003, Chicago, IL.
-
(2003)
XIV International Symposium on Drugs Affecting Lipid Metabolism
-
-
Ruano, G.1
-
76
-
-
2942527225
-
UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer
-
Sai, K., Saeki, M., Saito, Y., Ozawa, S., Katori, N., Jinno, H., Hasegawa, R., Kaniwa, N., Sawada, J., Komamura, K., Ueno, K., Kamakura, S., Kitakaze, M., Kitamura, Y., Kamatani, N., Minami, H., Ohtsu, A., Shirao, K., Yoshida, T., and Saijo, N. 2004. UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer. Clin. Pharmacol. Ther. 75:501-515.
-
(2004)
Clin. Pharmacol. Ther.
, vol.75
, pp. 501-515
-
-
Sai, K.1
Saeki, M.2
Saito, Y.3
Ozawa, S.4
Katori, N.5
Jinno, H.6
Hasegawa, R.7
Kaniwa, N.8
Sawada, J.9
Komamura, K.10
Ueno, K.11
Kamakura, S.12
Kitakaze, M.13
Kitamura, Y.14
Kamatani, N.15
Minami, H.16
Ohtsu, A.17
Shirao, K.18
Yoshida, T.19
Saijo, N.20
more..
-
77
-
-
3543145938
-
Pharmacogenomic data: FDA voluntary and required submission guidance
-
Salerno, R. A., and Lesko, L. J. 2004a. Pharmacogenomic data: FDA voluntary and required submission guidance. Pharmacogenomics 5:503-505.
-
(2004)
Pharmacogenomics
, vol.5
, pp. 503-505
-
-
Salerno, R.A.1
Lesko, L.J.2
-
78
-
-
0347136017
-
Pharmacogenomics in drug development and regulatory decision-making: The Genomic Data Submission (GDS) proposal
-
Salerno, R. A., and Lesko, L. J. 2004b. Pharmacogenomics in drug development and regulatory decision-making: The Genomic Data Submission (GDS) proposal. Pharmacogenomics 5:25-30.
-
(2004)
Pharmacogenomics
, vol.5
, pp. 25-30
-
-
Salerno, R.A.1
Lesko, L.J.2
-
79
-
-
2942527225
-
UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer
-
Sai, K., Saeki, M., Saito, Y., Ozawa, S., Katori, N., Jinno, H., Hasegawa, R., Kaniwa, N., Sawada, J., Komamura, K., Ueno, K., Kamakura, S., Kitakaze, M., Kitamura, Y., Kamatani, N., Minami, H., Ohtsu, A., Shirao, K., Yoshida, T., Saijo, N. 2004. UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer. Clin. Pharmacol. Ther. 75:501-515.
-
(2004)
Clin. Pharmacol. Ther.
, vol.75
, pp. 501-515
-
-
Sai, K.1
Saeki, M.2
Saito, Y.3
Ozawa, S.4
Katori, N.5
Jinno, H.6
Hasegawa, R.7
Kaniwa, N.8
Sawada, J.9
Komamura, K.10
Ueno, K.11
Kamakura, S.12
Kitakaze, M.13
Kitamura, Y.14
Kamatani, N.15
Minami, H.16
Ohtsu, A.17
Shirao, K.18
Yoshida, T.19
Saijo, N.20
more..
-
80
-
-
0037431040
-
Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB
-
Siddiqui, A., Kerb, R., Weale, M. E., Brinkmann, U., Smith, A., Goldstein, D. B., Wood, N. W., and Sisodiya, S. M. 2003. Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB. N. Engl. J. Med. 348:1442-1448.
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 1442-1448
-
-
Siddiqui, A.1
Kerb, R.2
Weale, M.E.3
Brinkmann, U.4
Smith, A.5
Goldstein, D.B.6
Wood, N.W.7
Sisodiya, S.M.8
-
81
-
-
0346602691
-
Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine
-
Stearns, V., Johnson, M. D., Rae, J. M., Morocho, A., Novielli, A., Bhargava, P., Hayes, D. F., Desta, Z., and Flockhart, D. A. 2003. Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine. J. Natl. Cancer Inst. 95:1758-1764.
-
(2003)
J. Natl. Cancer Inst.
, vol.95
, pp. 1758-1764
-
-
Stearns, V.1
Johnson, M.D.2
Rae, J.M.3
Morocho, A.4
Novielli, A.5
Bhargava, P.6
Hayes, D.F.7
Desta, Z.8
Flockhart, D.A.9
-
82
-
-
0037337016
-
Defining dose decrease.
-
Comment on Cross, J., Lee, H., Westelinck, A., Nelson, J., Grudzinskas, C., and Peck, C. Postmarketing drug dosage changes of 499 PDA-approved new molecular entities, 1980-1999. Pharmacoepidemiol. Drug Saf. 2002 11:439-16
-
Temple, R. J. 2003. Defining dose decrease. [Comment on Cross, J., Lee, H., Westelinck, A., Nelson, J., Grudzinskas, C., and Peck, C. Postmarketing drug dosage changes of 499 PDA-approved new molecular entities, 1980-1999. Pharmacoepidemiol. Drug Saf. 2002 11:439-16], Pharmacoepidemiol. Drug Saf. 12:151-152.
-
(2003)
Pharmacoepidemiol. Drug Saf.
, vol.12
, pp. 151-152
-
-
Temple, R.J.1
-
83
-
-
84866055387
-
-
Thorn, C.F., Carrillo, M. W., Ramirez, J., Marsh, S., Schuetz, E. G., Dolan, M. E., Innocenti, F., Relling, M. V., McLeod, H. L., and Ratain, M. J. Irinotecan pathway: http://www.pharmgkb.org/search/pathway/irinotecan/liver.jsp, last updated March 10, 2005.
-
Irinotecan Pathway
-
-
Thorn, C.F.1
Carrillo, M.W.2
Ramirez, J.3
Marsh, S.4
Schuetz, E.G.5
Dolan, M.E.6
Innocenti, F.7
Relling, M.V.8
McLeod, H.L.9
Ratain, M.J.10
-
84
-
-
3543101362
-
Pharmacogenomic data submissions to the FDA: Clinical case studies
-
Trepicchio, W. L., Williams, G. A., Essayan, D., Hall, S. T., Harty, L. C., Shaw, P. M., et al. 2004. Pharmacogenomic data submissions to the FDA: Clinical case studies. Pharmacogenomics 5:519-524.
-
(2004)
Pharmacogenomics
, vol.5
, pp. 519-524
-
-
Trepicchio, W.L.1
Williams, G.A.2
Essayan, D.3
Hall, S.T.4
Harty, L.C.5
Shaw, P.M.6
-
85
-
-
2942551228
-
Homozygous CYP2B6 *6 (Q172H and K262R) correlates with high plasma efavirenz concentrations in HIV-1 patients treated with standard efavirenz-containing regimens
-
Jul 9
-
Tsuchiya, K., Gatanaga, H., Tachikawa, N., Teruya, K., Kikuchi, Y., Yoshino, M., Kuwahara, T., Shirasaka, T., Kimura, S., and Oka, S. 2004. Homozygous CYP2B6 *6 (Q172H and K262R) correlates with high plasma efavirenz concentrations in HIV-1 patients treated with standard efavirenz-containing regimens. Biochem. Biophys. Res. Commun. Jul 9; 319(4):1322-1326.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.319
, Issue.4
, pp. 1322-1326
-
-
Tsuchiya, K.1
Gatanaga, H.2
Tachikawa, N.3
Teruya, K.4
Kikuchi, Y.5
Yoshino, M.6
Kuwahara, T.7
Shirasaka, T.8
Kimura, S.9
Oka, S.10
-
86
-
-
0034891594
-
Analysis of the C YP2D6 gene polymorphism and enzyme activity in African-Americans in southern California
-
Wan, Y. J., Poland, R. E., Han, G., Konishi, T., Zheng, Y. P., Berman, N., and Lin, K. M. 2001. Analysis of the C YP2D6 gene polymorphism and enzyme activity in African-Americans in southern California. Pharmacogenetics 11:489-499.
-
(2001)
Pharmacogenetics
, vol.11
, pp. 489-499
-
-
Wan, Y.J.1
Poland, R.E.2
Han, G.3
Konishi, T.4
Zheng, Y.P.5
Berman, N.6
Lin, K.M.7
-
87
-
-
0037421584
-
Inheritance and drug response
-
Weinshilboum, R. 2003. Inheritance and drug response. N. Engl. J. Med. 348:529-537.
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 529-537
-
-
Weinshilboum, R.1
-
88
-
-
0035056404
-
Thiopurine pharmacogenetics: Clinical and molecular studies of thiopurine methyltransferase
-
Weinshilboum, R. 2001. Thiopurine pharmacogenetics: Clinical and molecular studies of thiopurine methyltransferase. Drug. Metab. Dispos. 29(4 Pt 2): 601-605.
-
(2001)
Drug. Metab. Dispos.
, vol.29
, Issue.4 PART 2
, pp. 601-605
-
-
Weinshilboum, R.1
-
90
-
-
0035028479
-
Molecular basis of ethnic differences in drug disposition and response
-
Xie, H. G., Kim, R. B., Wood, A. J., and Stein, C. M. 2001. Molecular basis of ethnic differences in drug disposition and response. Annu. Rev. Pharmacol. Toxicol. 41:815-850.
-
(2001)
Annu. Rev. Pharmacol. Toxicol.
, vol.41
, pp. 815-850
-
-
Xie, H.G.1
Kim, R.B.2
Wood, A.J.3
Stein, C.M.4
-
91
-
-
0036299144
-
An in vivo pilot study characterizing the new CYP2A6*7, *8, and *10 alleles
-
Xu, C., Rao, Y. S., Xu, B., Hoffmann, E., Jones, J., Sellers, E. M., and Tyndale, R. F. 2002. An in vivo pilot study characterizing the new CYP2A6*7, *8, and *10 alleles. Biochem. Biophys. Res. Commun. 290:318-324.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.290
, pp. 318-324
-
-
Xu, C.1
Rao, Y.S.2
Xu, B.3
Hoffmann, E.4
Jones, J.5
Sellers, E.M.6
Tyndale, R.F.7
-
92
-
-
0037161355
-
Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes
-
Yang, P., Kanki, H., Drolet, B., Yang, T., Wei, J., Viswanathan, P. C., Hohnloser, S. H., Shimizu, W., Schwartz, P. J., Stanton, M., Murray, K. T., Norris, K., George, A. L. Jr., and Roden, D. M. 2002. Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes. Circulation 105:1943-1948.
-
(2002)
Circulation
, vol.105
, pp. 1943-1948
-
-
Yang, P.1
Kanki, H.2
Drolet, B.3
Yang, T.4
Wei, J.5
Viswanathan, P.C.6
Hohnloser, S.H.7
Shimizu, W.8
Schwartz, P.J.9
Stanton, M.10
Murray, K.T.11
Norris, K.12
George Jr., A.L.13
Roden, D.M.14
-
93
-
-
1942423665
-
Different inhibitory effect of fluvoxamine on omeprazole metabolism between CYP2C19 genotypes
-
Yasui-Furukori, N., Takahata, T., Nakagami, T., Yoshiya, G., Inoue, Y., Kaneko, S., and Tateishi, T. 2004. Different inhibitory effect of fluvoxamine on omeprazole metabolism between CYP2C19 genotypes. Br. J. Clin. Pharmacol. 57:487-494.
-
(2004)
Br. J. Clin. Pharmacol.
, vol.57
, pp. 487-494
-
-
Yasui-Furukori, N.1
Takahata, T.2
Nakagami, T.3
Yoshiya, G.4
Inoue, Y.5
Kaneko, S.6
Tateishi, T.7
-
94
-
-
11144232127
-
Pharmacogenetics and herb-drug interactions: Experience with Ginkgo bilobaand omeprazole
-
in press
-
Yin, O. Q. P., Tomlinson, B., Waye, M. M. Y., Chow, A. H. L., and Chow, M. S. S. Pharmacogenetics and herb-drug interactions: Experience with Ginkgo bilobaand omeprazole. Pharmacogenetics (in press).
-
Pharmacogenetics
-
-
Yin, O.Q.P.1
Tomlinson, B.2
Waye, M.M.Y.3
Chow, A.H.L.4
Chow, M.S.S.5
-
95
-
-
9144245517
-
Tacrolimus dosing in adult lung transplant patients is related to cytochrome P4503A5 gene polymorphism
-
Zheng, H., Zeevi, A., Schuetz, E., Lamba, J., McCurry, K., Griffith, B. P., Webber, S., Ristich, J., Dauber, J., Iacono, A., Grgurich, W., Zaldonis, D., McDade, K., Zhang, J., and Burckart, G. J. 2004. Tacrolimus dosing in adult lung transplant patients is related to cytochrome P4503A5 gene polymorphism. J. Clin. Pharmacol. 44:135-140.
-
(2004)
J. Clin. Pharmacol.
, vol.44
, pp. 135-140
-
-
Zheng, H.1
Zeevi, A.2
Schuetz, E.3
Lamba, J.4
McCurry, K.5
Griffith, B.P.6
Webber, S.7
Ristich, J.8
Dauber, J.9
Iacono, A.10
Grgurich, W.11
Zaldonis, D.12
McDade, K.13
Zhang, J.14
Burckart, G.J.15
-
96
-
-
2342527023
-
Interleukin-10 production genotype protects against acute persistent rejection after lung transplantation
-
Zheng, H. X., Burckart, G. J., McCurry, K., Webber, S., Ristich, J., Iacono, A., Dauber, J., McDade, K., Grgurich, W., Zaldonis, D., Pillage, G., Griffith, B. P., and Zeevi, A. 2004. Interleukin-10 production genotype protects against acute persistent rejection after lung transplantation. J. Heart Lung Transplant. 23:541-546.
-
(2004)
J. Heart Lung Transplant.
, vol.23
, pp. 541-546
-
-
Zheng, H.X.1
Burckart, G.J.2
McCurry, K.3
Webber, S.4
Ristich, J.5
Iacono, A.6
Dauber, J.7
McDade, K.8
Grgurich, W.9
Zaldonis, D.10
Pillage, G.11
Griffith, B.P.12
Zeevi, A.13
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