-
1
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
Lander, E. S. et al. Initial sequencing and analysis of the human genome. Nature 409, 860-921 (2001).
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
Lander, E.S.1
-
2
-
-
0035895505
-
The sequence of the human genome
-
Venter, J. C. et al. The sequence of the human genome. Science 291, 1304-1351 (2001)
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
-
4
-
-
0003680152
-
-
(McGraw-Hill Medical, New York,)
-
Hardman, J. G., Limbird, L. E. & Gilman, A. G. The Pharmacological Basis of Therapeutics (McGraw-Hill Medical, New York, 2001).
-
(2001)
The Pharmacological Basis of Therapeutics
-
-
Hardman, J.G.1
Limbird, L.E.2
Gilman, A.G.3
-
6
-
-
0004120124
-
-
(Oxford Univ. Press, New York,)
-
Weber, W. W. Pharmacogenetics (Oxford Univ. Press, New York, 1997).
-
(1997)
Pharmacogenetics
-
-
Weber, W.W.1
-
8
-
-
0014383735
-
Genetic control of dicumarol levels in man
-
Vesell, E. S. & Page, J. G. Genetic control of dicumarol levels in man. J. Clin. Invest. 47, 2657-2663 (1968).
-
(1968)
J. Clin. Invest.
, vol.47
, pp. 2657-2663
-
-
Vesell, E.S.1
Page, J.G.2
-
9
-
-
0014403645
-
Genetic control of drug levels in man: Antipyrine
-
Vesell, E. S. & Page, J. G. Genetic control of drug levels in man: antipyrine. Science 161, 72-73 (1968).
-
(1968)
Science
, vol.161
, pp. 72-73
-
-
Vesell, E.S.1
Page, J.G.2
-
10
-
-
0002485410
-
-
(eds. Hardman, J. G., Limbird, L. E. & Gilman, A. G.) (McGraw-Hill Medical, New York,)
-
Wilkinson, G. R. in The Pharmacological Basis of Therapeutics (eds. Hardman, J. G., Limbird, L. E. & Gilman, A. G.) 3-29 (McGraw-Hill Medical, New York, 2001).
-
(2001)
The Pharmacological Basis of Therapeutics
, pp. 3-29
-
-
Wilkinson, G.R.1
-
11
-
-
0002202499
-
-
(ed. Kalow, W.) (Pergamon, New York,)
-
Price Evans, D. A. in Pharmacogenetics of Drug Metabolism. International Encyclopedia of Pharmacology and Therapeutics Vol. 34 (ed. Kalow, W.) 95-178 (Pergamon, New York, 1992).
-
(1992)
Pharmacogenetics of Drug Metabolism. International Encyclopedia of Pharmacology and Therapeutics
, vol.34
, pp. 95-178
-
-
Price Evans, D.A.1
-
12
-
-
0018969976
-
Polymorphic acetylation of hydralazine
-
Timbrell, J. A., Harland, S. J. & Facchini, V. Polymorphic acetylation of hydralazine. Clin. Pharmacol. Ther. 28, 350-355 (1980).
-
(1980)
Clin. Pharmacol. Ther.
, vol.28
, pp. 350-355
-
-
Timbrell, J.A.1
Harland, S.J.2
Facchini, V.3
-
13
-
-
0016735879
-
Polymorphic acetylation of procainamide in man
-
Reidenberg, M. M., Drayer, D. E., Levy, M. & Warner, H. Polymorphic acetylation of procainamide in man. Clin. Pharmacol. Ther. 17, 722-730 (1975).
-
(1975)
Clin. Pharmacol. Ther.
, vol.17
, pp. 722-730
-
-
Reidenberg, M.M.1
Drayer, D.E.2
Levy, M.3
Warner, H.4
-
14
-
-
0017398371
-
Clinical consequences of polymorphic acetylation of basic drugs
-
Drayer, D. E. & Reidenberg, M. M. Clinical consequences of polymorphic acetylation of basic drugs. Clin. Pharmacol. Ther. 22, 251-258 (1977).
-
(1977)
Clin. Pharmacol. Ther.
, vol.22
, pp. 251-258
-
-
Drayer, D.E.1
Reidenberg, M.M.2
-
15
-
-
26444539817
-
Genetic control of isoniazid metabolism in man
-
Price Evans, D. A., Manley, K. A. & McKusick, V. A. Genetic control of isoniazid metabolism in man. BMJ 2, 485-491 (1960).
-
(1960)
BMJ
, vol.2
, pp. 485-491
-
-
Price Evans, D.A.1
Manley, K.A.2
McKusick, V.A.3
-
16
-
-
0018822866
-
Mercaptopurine pharmacogenetics: Monogenic inheritance of erythrocyte thiopurine methyltransferase activity
-
Weinshilboum, R. M. & Sladek, S. L. Mercaptopurine pharmacogenetics: Monogenic inheritance of erythrocyte thiopurine methyltransferase activity. Am. J. Hum. Genet. 32, 651-662 (1980).
-
(1980)
Am. J. Hum. Genet.
, vol.32
, pp. 651-662
-
-
Weinshilboum, R.M.1
Sladek, S.L.2
-
17
-
-
0032921854
-
Methylation pharmacogenetics: Catechol O-methyltransferase, thiopurine methyltransferase, and histamine N-methyltransferase
-
Weinshilboum, R. M., Otterness, D. M. & Szumlanski, C. L. Methylation pharmacogenetics: catechol O-methyltransferase, thiopurine methyltransferase, and histamine N-methyltransferase. Annu. Rev. Pharmacol. Toxicol. 39, 19-52 (1999).
-
(1999)
Annu. Rev. Pharmacol. Toxicol.
, vol.39
, pp. 19-52
-
-
Weinshilboum, R.M.1
Otterness, D.M.2
Szumlanski, C.L.3
-
18
-
-
0017695082
-
Polymorphic hydroxylation of debrisoquine in man
-
Mahgoub, A., Idle, J. R., Dring, L. G., Lancaster, R. & Smith, R. L. Polymorphic hydroxylation of debrisoquine in man. Lancet 2, 584-586 (1977).
-
(1977)
Lancet
, vol.2
, pp. 584-586
-
-
Mahgoub, A.1
Idle, J.R.2
Dring, L.G.3
Lancaster, R.4
Smith, R.L.5
-
19
-
-
0028997955
-
'It's the genes, stupid'. Molecular bases and clinical consequences of genetic cytochrome P450 2D6 polymorphism
-
Kroemer, H. K. & Eichelbaum, M. 'It's the genes, stupid'. Molecular bases and clinical consequences of genetic cytochrome P450 2D6 polymorphism. Life Sci. 56, 2285-2298 (1995).
-
(1995)
Life Sci.
, vol.56
, pp. 2285-2298
-
-
Kroemer, H.K.1
Eichelbaum, M.2
-
20
-
-
0026506140
-
Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin
-
Bertilsson, L. et al. Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin. Clin. Pharmacol. Ther. 51, 388-397 (1992).
-
(1992)
Clin. Pharmacol. Ther.
, vol.51
, pp. 388-397
-
-
Bertilsson, L.1
-
21
-
-
0023954396
-
Human debrisoquine 4-hydroxylase (P450IID1): cDNA and deduced amino acid sequence and assignment of the CYP2D locus of chromosome 22
-
Gonzalez, F. J. et al. Human debrisoquine 4-hydroxylase (P450IID1): cDNA and deduced amino acid sequence and assignment of the CYP2D locus of chromosome 22. Genomics 2, 174-179 (1988).
-
(1988)
Genomics
, vol.2
, pp. 174-179
-
-
Gonzalez, F.J.1
-
22
-
-
0034796765
-
Unraveling the functional genomics of the human CYP2D6 gene locus
-
Ingelman-Sundberg, M. & Evans, W. Unraveling the functional genomics of the human CYP2D6 gene locus. Pharmacogenetics 11, 553-554 (2001).
-
(2001)
Pharmacogenetics
, vol.11
, pp. 553-554
-
-
Ingelman-Sundberg, M.1
Evans, W.2
-
23
-
-
0027136288
-
Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine
-
Johansson, I. et al. Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine. Proc. Natl Acad. Sci. USA 90, 11825-11829 (1993).
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 11825-11829
-
-
Johansson, I.1
-
24
-
-
0030432585
-
Frequent distribution of ultrarapid metabolizers of debrisoquine in the Ethiopian population carrying duplicated and multiduplicated functional CYP2D6 alleles
-
Aklillu, E. et al. Frequent distribution of ultrarapid metabolizers of debrisoquine in the Ethiopian population carrying duplicated and multiduplicated functional CYP2D6 alleles. J. Pharmacol. Exp. Ther. 278, 441-446 (1996).
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.278
, pp. 441-446
-
-
Aklillu, E.1
-
25
-
-
1342346660
-
'Draft' Guidance for Industry: Pharmacogenomics Data Submissions
-
US Department of Health and Human Services Food and Drug Administration, Center for Drug Evaluation and Research, Center for Biologics Evaluation and Research & Center for Devices and Radiological Health. (November
-
US Department of Health and Human Services Food and Drug Administration, Center for Drug Evaluation and Research, Center for Biologics Evaluation and Research & Center for Devices and Radiological Health. 'Draft' Guidance for Industry: Pharmacogenomics Data Submissions. (November 2003).
-
(2003)
-
-
-
26
-
-
0018615011
-
Defective N-oxidation of sparteine in man: A new pharmacogenetic defect
-
Eichelbaum, M., Spannbrucker, N., Steincke, B. & Dengler, H. J. Defective N-oxidation of sparteine in man: a new pharmacogenetic defect. Eur. J. Clin. Pharmacol. 16, 183-187 (1979).
-
(1979)
Eur. J. Clin. Pharmacol.
, vol.16
, pp. 183-187
-
-
Eichelbaum, M.1
Spannbrucker, N.2
Steincke, B.3
Dengler, H.J.4
-
27
-
-
0024451147
-
Pharmacogenetics of acute azathioprine toxicity: Relationship to thiopurine methyltransferase genetic polymorphism
-
Lennard, L., Van Loon, J. A. & Weinshilboum, R. M. Pharmacogenetics of acute azathioprine toxicity: relationship to thiopurine methyltransferase genetic polymorphism. Clin. Pharmacol. Ther. 46, 149-154 (1989).
-
(1989)
Clin. Pharmacol. Ther.
, vol.46
, pp. 149-154
-
-
Lennard, L.1
Van Loon, J.A.2
Weinshilboum, R.M.3
-
28
-
-
0037421584
-
Inheritance and drug response
-
Weinshilboum, R. Inheritance and drug response. N. Engl. J. Med. 348, 529-537 (2003).
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 529-537
-
-
Weinshilboum, R.1
-
29
-
-
0027401302
-
Azathioprine-induced myelosuppression in thiopurine methyltransferase deficient heart transplant recipient
-
Schütz, E., Gummert, J., Mohr, F. & Oellerich, M. Azathioprine-induced myelosuppression in thiopurine methyltransferase deficient heart transplant recipient. Lancet. 341, 436 (1993).
-
(1993)
Lancet
, vol.341
, pp. 436
-
-
Schütz, E.1
Gummert, J.2
Mohr, F.3
Oellerich, M.4
-
31
-
-
0033059209
-
Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment
-
Drazen, J. M. et al. Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment. Nature Genet. 22, 168-170 (1999).
-
(1999)
Nature Genet.
, vol.22
, pp. 168-170
-
-
Drazen, J.M.1
-
32
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch, T. J. et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N. Engl. J. Med. 350, 2129-2139 (2004).
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
-
33
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez, J. G. et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 304, 1497-1500 (2004).
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
-
34
-
-
0036633359
-
Genome-based pharmacogenetics and the pharmaceutical industry
-
Roses, A. D. Genome-based pharmacogenetics and the pharmaceutical industry. Nature Rev. Drug Discov. 1, 541-549 (2002).
-
(2002)
Nature Rev. Drug Discov.
, vol.1
, pp. 541-549
-
-
Roses, A.D.1
-
36
-
-
0033168459
-
Shattuck lecture - Medical and societal consequences of the Human Genome Project
-
Collins, F. S. Shattuck lecture - medical and societal consequences of the Human Genome Project. N. Engl. J. Med. 341, 28-37 (1999).
-
(1999)
N. Engl. J. Med.
, vol.341
, pp. 28-37
-
-
Collins, F.S.1
-
37
-
-
0347185032
-
Pharmacogenomics and 'individualized drug therapy': High expectations and disappointing achievements
-
Nebert, D. W., Jorge-Nebert, L. & Vesell, E. S. Pharmacogenomics and 'individualized drug therapy': high expectations and disappointing achievements. Am. J. Pharmacogenomics 3, 361-370 (2003).
-
(2003)
Am. J. Pharmacogenomics
, vol.3
, pp. 361-370
-
-
Nebert, D.W.1
Jorge-Nebert, L.2
Vesell, E.S.3
-
38
-
-
79959503826
-
The International HapMap Project
-
Consortium, T. I. H. The International HapMap Project. Nature 426, 789-796 (2003).
-
(2003)
Nature
, vol.426
, pp. 789-796
-
-
Consortium, T.I.H.1
-
39
-
-
0034930262
-
The relative power of SNPs and haplotypes as genetic markers for association tests
-
Bader, J. The relative power of SNPs and haplotypes as genetic markers for association tests. Pharmacogenomics 2, 11-24 (2001).
-
(2001)
Pharmacogenomics
, vol.2
, pp. 11-24
-
-
Bader, J.1
-
40
-
-
0141642224
-
The NIH Roadmap
-
Zerhouni, E. The NIH Roadmap. Science 302, 63-72 (2003).
-
(2003)
Science
, vol.302
, pp. 63-72
-
-
Zerhouni, E.1
-
41
-
-
1342310916
-
PharmGKB: The pharmacogenetics and pharmacogenomics knowledge base
-
Klein, T. E. & Altman, R. B. PharmGKB: the pharmacogenetics and pharmacogenomics knowledge base. Pharmacogenomics J. 4, 1 (2004).
-
(2004)
Pharmacogenomics J.
, vol.4
, pp. 1
-
-
Klein, T.E.1
Altman, R.B.2
-
42
-
-
1642354534
-
Surviving the blockbuster syndrome
-
Service, R. F. Surviving the blockbuster syndrome. Science 303, 1796-1799 (2004).
-
(2004)
Science
, vol.303
, pp. 1796-1799
-
-
Service, R.F.1
-
43
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon, D. J. et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N. Engl. J. Med. 344, 783-792 (2001).
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
-
44
-
-
0035869520
-
From the molecule to the clinic - Inhibiting HER2 to treat breast cancer
-
Eisenhauer, E. A. From the molecule to the clinic - inhibiting HER2 to treat breast cancer. N. Engl. J. Med. 344, 841-842 (2001).
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 841-842
-
-
Eisenhauer, E.A.1
-
45
-
-
3543145938
-
Pharmacogenomic data: FDA voluntary and required submission guidance
-
Salerno, R. A. & Lesko, L. J. Pharmacogenomic data: FDA voluntary and required submission guidance. Pharmacogenomics 5, 503-505 (2004).
-
(2004)
Pharmacogenomics
, vol.5
, pp. 503-505
-
-
Salerno, R.A.1
Lesko, L.J.2
-
46
-
-
3543063976
-
Pharmacogenomic data submissions to the FDA: Non-clinical case studies
-
Leighton, J. K. et al. Pharmacogenomic data submissions to the FDA: non-clinical case studies. Pharmacogenomics 5, 507-511 (2004).
-
(2004)
Pharmacogenomics
, vol.5
, pp. 507-511
-
-
Leighton, J.K.1
-
47
-
-
3543080360
-
Pharmacogenomic data submissions to the FDA: Clinical pharmacology case studies
-
Ruano, G. et al. Pharmacogenomic data submissions to the FDA: clinical pharmacology case studies. Pharmacogenomics 5, 513-517 (2004).
-
(2004)
Pharmacogenomics
, vol.5
, pp. 513-517
-
-
Ruano, G.1
-
48
-
-
3543101362
-
Pharmacogenomic data submissions to the FDA: Clinical case studies
-
Trepicchio, W. L. et al. Pharmacogenomic data submissions to the FDA: clinical case studies. Pharmacogenomics 5, 519-524 (2004).
-
(2004)
Pharmacogenomics
, vol.5
, pp. 519-524
-
-
Trepicchio, W.L.1
-
49
-
-
0028867826
-
The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome
-
Bosma, P. J. et al. The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome. N. Engl. J. Med. 333, 1171-1175 (1995).
-
(1995)
N. Engl. J. Med.
, vol.333
, pp. 1171-1175
-
-
Bosma, P.J.1
-
50
-
-
0037230622
-
Inherited disorders of bilirubin metabolism
-
Bosma, P. J. Inherited disorders of bilirubin metabolism. J. Hepatol. 38, 107-117 (2003).
-
(2003)
J. Hepatol.
, vol.38
, pp. 107-117
-
-
Bosma, P.J.1
-
51
-
-
0030030762
-
Genetic variation in bilirubin UPD-glucurono-syltransferase gene promoter and Gilbert's syndrome
-
Monaghan, G., Ryan, M., Seddon, R., Hume, R. & Burchell, B. Genetic variation in bilirubin UPD-glucurono-syltransferase gene promoter and Gilbert's syndrome. Lancet 347, 578-581 (1996).
-
(1996)
Lancet
, vol.347
, pp. 578-581
-
-
Monaghan, G.1
Ryan, M.2
Seddon, R.3
Hume, R.4
Burchell, B.5
-
52
-
-
2942597859
-
'Irinogenetics' and UGT1A: From genotypes to haplotypes
-
Innocenti, F. & Ratain, M. J. 'Irinogenetics' and UGT1A: from genotypes to haplotypes. Clin. Pharmacol. Ther. 75, 495-500 (2004).
-
(2004)
Clin. Pharmacol. Ther.
, vol.75
, pp. 495-500
-
-
Innocenti, F.1
Ratain, M.J.2
-
53
-
-
4344659029
-
-
(Johns Hopkins Univ. Press, Baltimore,)
-
Guttmacher, A. E., Collins, F. S. & Drazen, J. M. Genomic Medicine (Johns Hopkins Univ. Press, Baltimore, 2004).
-
(2004)
Genomic Medicine
-
-
Guttmacher, A.E.1
Collins, F.S.2
Drazen, J.M.3
-
56
-
-
0042855876
-
Ethical, legal, and social implications of genomic medicine
-
Clayton, E. W. Ethical, legal, and social implications of genomic medicine. N. Engl. J. Med. 349, 562-569 (2003).
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 562-569
-
-
Clayton, E.W.1
-
57
-
-
0000609893
-
Metabolism of thiopyrimidines and thiopurines: S-methylation with S- adenosylmethionine transmethylase and catabolism in mammalian tissue
-
Remy, C. N. Metabolism of thiopyrimidines and thiopurines: S-methylation with S- adenosylmethionine transmethylase and catabolism in mammalian tissue. J. Biol. Chem. 238, 1078-1084 (1963).
-
(1963)
J. Biol. Chem.
, vol.238
, pp. 1078-1084
-
-
Remy, C.N.1
-
58
-
-
0020640116
-
Human kidney thiopurine methyltransferase: Purification and biochemical properties
-
Woodson, L. C. & Weinshilboum, R. M. Human kidney thiopurine methyltransferase: purification and biochemical properties. Biochem. Pharmacol. 32, 819-826 (1983).
-
(1983)
Biochem. Pharmacol.
, vol.32
, pp. 819-826
-
-
Woodson, L.C.1
Weinshilboum, R.M.2
-
59
-
-
0026758498
-
The clinical pharmacology of 6 mercaptopurine
-
Lennard, L. The clinical pharmacology of 6 mercaptopurine. Eur. J. Clin. Pharmacol. 43, 329-339 (1992).
-
(1992)
Eur. J. Clin. Pharmacol.
, vol.43
, pp. 329-339
-
-
Lennard, L.1
-
60
-
-
0030048791
-
Thiopurine methyltransferase pharmacogenetics: Human gene cloning and characterization of a common polymorphism
-
Szumlanski, C. et al. Thiopurine methyltransferase pharmacogenetics: human gene cloning and characterization of a common polymorphism. DNA Cell Biol. 15, 17-30 (1996).
-
(1996)
DNA Cell Biol.
, vol.15
, pp. 17-30
-
-
Szumlanski, C.1
-
61
-
-
3242762099
-
Comprehensive analysis of thiopurine S-methyltransferase phenotype-genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants
-
Schaeffeler, E. et al. Comprehensive analysis of thiopurine S-methyltransferase phenotype-genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants. Pharmacogenetics 14, 407-417 (2004).
-
(2004)
Pharmacogenetics
, vol.14
, pp. 407-417
-
-
Schaeffeler, E.1
-
62
-
-
0032917646
-
The frequency and distribution of thiopurine methyltransferase alleles in Caucasian and Asian populations
-
Collie-Duguid, E. S. R. et al. The frequency and distribution of thiopurine methyltransferase alleles in Caucasian and Asian populations. Pharmacogenetics 9, 37-42 (1998).
-
(1998)
Pharmacogenetics
, vol.9
, pp. 37-42
-
-
Collie-Duguid, E.S.R.1
-
63
-
-
0141761407
-
Thiopurine S-methyltransferase pharmacogenetics: Chaperone protein association and allozyme degradation
-
Wang, L., Sullivan, W., Toft, D. & Weinshilboum, R. Thiopurine S-methyltransferase pharmacogenetics: chaperone protein association and allozyme degradation. Pharmacogenetics 13, 555-564 (2003).
-
(2003)
Pharmacogenetics
, vol.13
, pp. 555-564
-
-
Wang, L.1
Sullivan, W.2
Toft, D.3
Weinshilboum, R.4
-
64
-
-
0030986251
-
Enhanced proteolysis of thiopurine S-methyltransferase (TPMT) encoded by mutant alleles in humans (TPMT*3A, TPMT*2): Mechanisms for the genetic polymorphism of TPMT activity
-
Tai, H.-L., Krynetski, E. Y., Schuetz, E. G., Yanishevski, Y. & Evans, W. E. Enhanced proteolysis of thiopurine S-methyltransferase (TPMT) encoded by mutant alleles in humans (TPMT*3A, TPMT*2): mechanisms for the genetic polymorphism of TPMT activity. Proc. Natl Acad. Sci. USA 94, 6444-6449 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 6444-6449
-
-
Tai, H.-L.1
Krynetski, E.Y.2
Schuetz, E.G.3
Yanishevski, Y.4
Evans, W.E.5
-
65
-
-
0019956940
-
Pharmacogenetics of human thiopurine methyltransferase: Kidney erythrocyte correlation and immunotitration studies
-
Woodson, L. C., Dunnette, J. H. & Weinshilboum, R. M. Pharmacogenetics of human thiopurine methyltransferase: kidney erythrocyte correlation and immunotitration studies. J. Pharmacol. Exp. Ther. 222, 174-181 (1982).
-
(1982)
J. Pharmacol. Exp. Ther.
, vol.222
, pp. 174-181
-
-
Woodson, L.C.1
Dunnette, J.H.2
Weinshilboum, R.M.3
-
66
-
-
1842687897
-
Pharmacogenetics: Inherited variation in amino acid sequence and altered protein quantity
-
Weinshilboum, R. & Wang, L. Pharmacogenetics: inherited variation in amino acid sequence and altered protein quantity. Clin. Pharmacol. Ther. 75, 253-258 (2004).
-
(2004)
Clin. Pharmacol. Ther.
, vol.75
, pp. 253-258
-
-
Weinshilboum, R.1
Wang, L.2
-
67
-
-
0025103215
-
Polymorphic formation of morphine from codeine in poor and extensive metabolizers of dextromethorphan: Relationship to the presence of immunoidentified cytochrome P-450IID1
-
Mortimer, O. et al. Polymorphic formation of morphine from codeine in poor and extensive metabolizers of dextromethorphan: relationship to the presence of immunoidentified cytochrome P-450IID1. Clin. Pharmacol. Ther. 47, 27-35 (1990).
-
(1990)
Clin. Pharmacol. Ther.
, vol.47
, pp. 27-35
-
-
Mortimer, O.1
-
68
-
-
0029622428
-
The pharmacogenetics of codeine hypoalgesia
-
Sindrup, S. H. & Broser, K. The pharmacogenetics of codeine hypoalgesia. Pharmacogenetics 5, 335-346 (1995).
-
(1995)
Pharmacogenetics
, vol.5
, pp. 335-346
-
-
Sindrup, S.H.1
Broser, K.2
-
69
-
-
0014823763
-
Relationship of acetyl transferase activity to antinuclear antibodies and toxic symptoms to hypertensive patients treated with hydralazine
-
Perry Jr, H. M., Tan, E. M., Carmody, S. & Sakamoto, A. Relationship of acetyl transferase activity to antinuclear antibodies and toxic symptoms to hypertensive patients treated with hydralazine. J. Lab. Clin. Med. 76, 1140125 (1970).
-
(1970)
J. Lab. Clin. Med.
, vol.76
, pp. 1140125
-
-
Perry Jr., H.M.1
Tan, E.M.2
Carmody, S.3
Sakamoto, A.4
-
70
-
-
0018099670
-
Effect of acetylator phenotype on the rate at which procainamide induces antinuclear and the lupus syndrome
-
Woosley, R. L. et al. Effect of acetylator phenotype on the rate at which procainamide induces antinuclear and the lupus syndrome. N. Engl. J. Med. 298, 1157-1159 (1978).
-
(1978)
N. Engl. J. Med.
, vol.298
, pp. 1157-1159
-
-
Woosley, R.L.1
-
71
-
-
0344759188
-
Arylamine N-acetyltransferase activity in man
-
Cascorbi, I., Brockmoller, J., Mrozikiewicz, P. M., Muller, A. & Roots, I. Arylamine N-acetyltransferase activity in man. Drug Metab. Rev. 31, 489-502 (1999).
-
(1999)
Drug Metab. Rev.
, vol.31
, pp. 489-502
-
-
Cascorbi, I.1
Brockmoller, J.2
Mrozikiewicz, P.M.3
Muller, A.4
Roots, I.5
|