-
2
-
-
0036607597
-
The low-density lipoprotein receptor gene family: A cellular Swiss army knife?
-
Nykjaer A, Willnow TE. The low-density lipoprotein receptor gene family: a cellular Swiss army knife? Trends Cell Biol. 2002;12:273-80.
-
(2002)
Trends Cell Biol
, vol.12
, pp. 273-280
-
-
Nykjaer, A.1
Willnow, T.E.2
-
3
-
-
0016241915
-
Binding and degradation of low density lipoproteins by cultured human fibroblasts
-
Goldstein JL, Brown MS. Binding and degradation of low density lipoproteins by cultured human fibroblasts. J Biol Chem. 1974;249:5133-62.
-
(1974)
J Biol Chem
, vol.249
, pp. 5133-5162
-
-
Goldstein, J.L.1
Brown, M.S.2
-
5
-
-
8444251784
-
The Wnt signaling pathway in development and disease
-
Logan CY, Nusse R. The Wnt signaling pathway in development and disease. Annu Rev Cell Dev. Biol. 2004;20:781-810.
-
(2004)
Annu Rev Cell Dev Biol
, vol.20
, pp. 781-810
-
-
Logan, C.Y.1
Nusse, R.2
-
6
-
-
5044228112
-
Wnt signaling in osteoblasts and bone diseases
-
Westendorf JJ, Kahler RA, Schroeder TM. Wnt signaling in osteoblasts and bone diseases. Gene. 2004;341:19-39.
-
(2004)
Gene
, vol.341
, pp. 19-39
-
-
Westendorf, J.J.1
Kahler, R.A.2
Schroeder, T.M.3
-
7
-
-
0034214847
-
The Wnt/Ca+2 pathway: A new vertebrate Wnt signaling pathway takes shape
-
Kuhl M, Sheldahl LC, Park M, Miller JR, Moon RT. The Wnt/Ca+2 pathway: a new vertebrate Wnt signaling pathway takes shape. Trends Genet. 2000;16:279-83.
-
(2000)
Trends Genet
, vol.16
, pp. 279-283
-
-
Kuhl, M.1
Sheldahl, L.C.2
Park, M.3
Miller, J.R.4
Moon, R.T.5
-
8
-
-
0036843202
-
Planar cell polarization: Do the same mechanisms regulate Drosophila tissue polarity and vertebrate gastrulation?
-
Mlodzik M. Planar cell polarization: do the same mechanisms regulate Drosophila tissue polarity and vertebrate gastrulation? Trends Genet. 2002;18:564-71.
-
(2002)
Trends Genet
, vol.18
, pp. 564-571
-
-
Mlodzik, M.1
-
9
-
-
0032446373
-
A new low density lipoprotein receptor related protein, LRP5, is expressed in hepatocytes and adrenal cortex, and recognizes apolipoprotein E
-
Kim DH, Inagaki Y, Suzuki T, Ioka RX, Yoshioka SZ, Magoori K, Kang MJ, Cho Y, Nakano AZ, Liu Q, Fujino T, Suzuki H, Sasano H, Yamamoto TT. A new low density lipoprotein receptor related protein, LRP5, is expressed in hepatocytes and adrenal cortex, and recognizes apolipoprotein E. Eur J Biochem. 1998;124:1072-6.
-
(1998)
Eur J Biochem
, vol.124
, pp. 1072-1076
-
-
Kim, D.H.1
Inagaki, Y.2
Suzuki, T.3
Ioka, R.X.4
Yoshioka, S.Z.5
Magoori, K.6
Kang, M.J.7
Cho, Y.8
Nakano, A.Z.9
Liu, Q.10
Fujino, T.11
Suzuki, H.12
Sasano, H.13
Yamamoto, T.T.14
-
10
-
-
0032578783
-
Molecular cloning and characterization of LR3, a novel LDL receptor family protein with mitogenic activity
-
Dong Y, Lathrop W, Weaver D, Qiu Q, Cini J, Bertolini D, Chen D. Molecular cloning and characterization of LR3, a novel LDL receptor family protein with mitogenic activity. Biochem Biophys Res Commun. 1998;251:784-90.
-
(1998)
Biochem Biophys Res Commun
, vol.251
, pp. 784-790
-
-
Dong, Y.1
Lathrop, W.2
Weaver, D.3
Qiu, Q.4
Cini, J.5
Bertolini, D.6
Chen, D.7
-
11
-
-
0032541395
-
Cloning of a novel member of the low-density lipoprotein receptor family
-
Hey PJ, Twells RC, Phillips MS, Yusuke N, Brown SD, Kawaguchi Y, Cox R, Guochun X, Dugan V, Hammond H, Metzker ML, Todd JA, Hess JF. Cloning of a novel member of the low-density lipoprotein receptor family. Gene. 1998;216:103-11.
-
(1998)
Gene
, vol.216
, pp. 103-111
-
-
Hey, P.J.1
Twells, R.C.2
Phillips, M.S.3
Yusuke, N.4
Brown, S.D.5
Kawaguchi, Y.6
Cox, R.7
Guochun, X.8
Dugan, V.9
Hammond, H.10
Metzker, M.L.11
Todd, J.A.12
Hess, J.F.13
-
12
-
-
0032581370
-
Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family
-
Brown SD, Twells RC, Hey PJ, Cox RD, Levy ER, Soderman AR, Metzker ML, Caskey CT, Todd JA, Hess JF. Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family. Biochem Biophys Res Commun. 1998;248:879-88.
-
(1998)
Biochem Biophys Res Commun
, vol.248
, pp. 879-888
-
-
Brown, S.D.1
Twells, R.C.2
Hey, P.J.3
Cox, R.D.4
Levy, E.R.5
Soderman, A.R.6
Metzker, M.L.7
Caskey, C.T.8
Todd, J.A.9
Hess, J.F.10
-
13
-
-
0034727099
-
Arrow encodes an LDL-receptor-related protein essential for Wingless signaling
-
Wehrli M, Dougan ST, Caldwell K, O'Keefe L, Schwartz S, Vaizel-Ohayon D, Schejter E, Tomlinson A, DiNardo S. Arrow encodes an LDL-receptor-related protein essential for Wingless signaling. Nature. 2000;407:527-30.
-
(2000)
Nature
, vol.407
, pp. 527-530
-
-
Wehrli, M.1
Dougan, S.T.2
Caldwell, K.3
O'Keefe, L.4
Schwartz, S.5
Vaizel-Ohayon, D.6
Schejter, E.7
Tomlinson, A.8
DiNardo, S.9
-
14
-
-
0037092049
-
Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor
-
Kato M, Patel MS, Levasseur R, Lobov I, Chang BH-J, Glass DA, Hartmann C, Li L, Hwang TH, Brayton CF, Lang RA, Karsenty G, Chan L. Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor. J Cell Biol. 2002;157:303-14.
-
(2002)
J Cell Biol
, vol.157
, pp. 303-314
-
-
Kato, M.1
Patel, M.S.2
Levasseur, R.3
Lobov, I.4
Chang, B.H.-J.5
Glass, D.A.6
Hartmann, C.7
Li, L.8
Hwang, T.H.9
Brayton, C.F.10
Lang, R.A.11
Karsenty, G.12
Chan, L.13
-
15
-
-
0032491379
-
An extracellular β-propeller module predicted in lipoprotein and scavenger receptors, tyrosine kinases, epidermal growth factor precursor, and extracellular matrix components
-
Springer TA. An extracellular β-propeller module predicted in lipoprotein and scavenger receptors, tyrosine kinases, epidermal growth factor precursor, and extracellular matrix components. J Mol Biol. 1998;283:837-62.
-
(1998)
J Mol Biol
, vol.283
, pp. 837-862
-
-
Springer, T.A.1
-
16
-
-
0035013711
-
Implications for familial hypercholesterolemia from the structure of the LDL receptor YWTD-EGF domain pair
-
Jeon H, Meng W, Takagi J, Eck MJ, Springer TA, Blacklow SC. Implications for familial hypercholesterolemia from the structure of the LDL receptor YWTD-EGF domain pair. Nat Struct Biol. 2001;8:499-504.
-
(2001)
Nat Struct Biol
, vol.8
, pp. 499-504
-
-
Jeon, H.1
Meng, W.2
Takagi, J.3
Eck, M.J.4
Springer, T.A.5
Blacklow, S.C.6
-
17
-
-
0037147281
-
Structure of the LDL receptor extracellular domain at endosomal pH
-
Rudenko G, Henry L, Henderson K, Ichtchenko K, Brown MS, Goldstein JL, Deisenhofer J. Structure of the LDL receptor extracellular domain at endosomal pH. Science. 2002;298:2353-8.
-
(2002)
Science
, vol.298
, pp. 2353-2358
-
-
Rudenko, G.1
Henry, L.2
Henderson, K.3
Ichtchenko, K.4
Brown, M.S.5
Goldstein, J.L.6
Deisenhofer, J.7
-
18
-
-
0041858013
-
Complex between nidogen and laminin fragments reveals a paradigmatic-propeller interface
-
Takagi J, Yang Y, Liu J, Wang J, Springer T. Complex between nidogen and laminin fragments reveals a paradigmatic-propeller interface. Nature. 2003;424:969-74.
-
(2003)
Nature
, vol.424
, pp. 969-974
-
-
Takagi, J.1
Yang, Y.2
Liu, J.3
Wang, J.4
Springer, T.5
-
19
-
-
0036138175
-
A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait
-
Little RD, Carulli JP, Del Mastro RG, Dupuis J, Osborne M, Folz C, Manning SP, Swain PM, Zhao SC, Eustace B, Lappe MM, Spitzer L, Zweier S, Braunschweiger K, Benchekroun Y, Hu X, Adair R, Chee L, FitzGerald MG, Tulig C, Caruso A, Tzellas N, Bawa A, Franklin B, McGuire S, Nogues X, Gong G, Allen KM, Anisowicz A, Morales AJ, Lomedico PT, Recker SM, Van Eerdewegh P, Recker RR, Johnson ML. A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait. Am J Hum Genet. 2002;70:11-9.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 11-19
-
-
Little, R.D.1
Carulli, J.P.2
Del Mastro, R.G.3
Dupuis, J.4
Osborne, M.5
Folz, C.6
Manning, S.P.7
Swain, P.M.8
Zhao, S.C.9
Eustace, B.10
Lappe, M.M.11
Spitzer, L.12
Zweier, S.13
Braunschweiger, K.14
Benchekroun, Y.15
Hu, X.16
Adair, R.17
Chee, L.18
FitzGerald, M.G.19
Tulig, C.20
Caruso, A.21
Tzellas, N.22
Bawa, A.23
Franklin, B.24
McGuire, S.25
Nogues, X.26
Gong, G.27
Allen, K.M.28
Anisowicz, A.29
Morales, A.J.30
Lomedico, P.T.31
Recker, S.M.32
Van Eerdewegh, P.33
Recker, R.R.34
Johnson, M.L.35
more..
-
20
-
-
18044386744
-
LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development
-
Gong Y, Slee RB, Fukai N, Rawadi G, Roman-Roman S, Reginato AM, Wang H, Cundy T, Glorieux FH, Lev D, Zacharin M, Oexle K, Marcelino J, Suwairi W, Heeger S, Sabatakos G, Apte S, Adkins WN, Allgrove J, Arsian-Kirchner M, Batch JA, Beighton P, Black GCM, Boles RG, Boon LM, Borrone C, Brunner HG, Carle GF, Dallapiccola B, De Paepa A, Floege B, Halfide ML, Hall B, Hennekam RC, Hirose T, Jans A, Juppner H, Kim CA, Keppler-Noreuil K, Kohlschuetter A, LaCombe D, Lambert M, Lemyre E, Letteboer T, Peltonen L, Ramesar RS, Romanengo M, Somer H, Steichen-Gersdorf E, Steinmann B, Sullivan B, Superta-Furga A, Swoboda W, van den Boogaard M-J, Van Hul W, Vikkula M, Votruba M, Zabel B, Garcia T, Baron R, Olsen BR, Warman ML. LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. Cell. 2001;107:513-23.
-
(2001)
Cell
, vol.107
, pp. 513-523
-
-
Gong, Y.1
Slee, R.B.2
Fukai, N.3
Rawadi, G.4
Roman-Roman, S.5
Reginato, A.M.6
Wang, H.7
Cundy, T.8
Glorieux, F.H.9
Lev, D.10
Zacharin, M.11
Oexle, K.12
Marcelino, J.13
Suwairi, W.14
Heeger, S.15
Sabatakos, G.16
Apte, S.17
Adkins, W.N.18
Allgrove, J.19
Arsian-Kirchner, M.20
Batch, J.A.21
Beighton, P.22
Black, G.C.M.23
Boles, R.G.24
Boon, L.M.25
Borrone, C.26
Brunner, H.G.27
Carle, G.F.28
Dallapiccola, B.29
De Paepa, A.30
Floege, B.31
Halfide, M.L.32
Hall, B.33
Hennekam, R.C.34
Hirose, T.35
Jans, A.36
Juppner, H.37
Kim, C.A.38
Keppler-Noreuil, K.39
Kohlschuetter, A.40
LaCombe, D.41
Lambert, M.42
Lemyre, E.43
Letteboer, T.44
Peltonen, L.45
Ramesar, R.S.46
Romanengo, M.47
Somer, H.48
Steichen-Gersdorf, E.49
Steinmann, B.50
Sullivan, B.51
Superta-Furga, A.52
Swoboda, W.53
Van Den Boogaard, M.-J.54
Van Hul, W.55
Vikkula, M.56
Votruba, M.57
Zabel, B.58
Garcia, T.59
Baron, R.60
Olsen, B.R.61
Warman, M.L.62
more..
-
21
-
-
0037118285
-
High bone density due to a mutation in LDL-receptor-related protein 5
-
Boyden LM, Mao J, Belsky J, Mitzner L, Farhi A, Mitnick MA, Wu D, Insogna K, Lifton RP. High bone density due to a mutation in LDL-receptor-related protein 5. N Engl J Med. 2002;346(20):1513-21.
-
(2002)
N Engl J Med
, vol.346
, Issue.20
, pp. 1513-1521
-
-
Boyden, L.M.1
Mao, J.2
Belsky, J.3
Mitzner, L.4
Farhi, A.5
Mitnick, M.A.6
Wu, D.7
Insogna, K.8
Lifton, R.P.9
-
22
-
-
0037030681
-
Kremen proteins are Dickkopf receptors that regulate Wnt/B-catenin signalling
-
Mao B, Wu W, Davidson G, Marhold J, Li M, Mechler BM, Delius J, Hoppe D, Stannek P, Walter C, Glinka A, Niehrs C. Kremen proteins are Dickkopf receptors that regulate Wnt/B-catenin signalling. Nature. 2002;417:664-7.
-
(2002)
Nature
, vol.417
, pp. 664-667
-
-
Mao, B.1
Wu, W.2
Davidson, G.3
Marhold, J.4
Li, M.5
Mechler, B.M.6
Delius, J.7
Hoppe, D.8
Stannek, P.9
Walter, C.10
Glinka, A.11
Niehrs, C.12
-
23
-
-
0037373341
-
Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density
-
Van Wesenbeeck E, Cleiren E, Gram J, Beals R, Benichou O, Scopelliti D, Key L, Renton T, Bartles C, Gong Y, Warman M, Vernejoul M, Bollerslev J, Van Hul W. Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density. Am J Hum Genet. 2003;72:763-71.
-
(2003)
Am J Hum Genet
, vol.72
, pp. 763-771
-
-
Van Wesenbeeck, E.1
Cleiren, E.2
Gram, J.3
Beals, R.4
Benichou, O.5
Scopelliti, D.6
Key, L.7
Renton, T.8
Bartles, C.9
Gong, Y.10
Warman, M.11
Vernejoul, M.12
Bollerslev, J.13
Van Hul, W.14
-
25
-
-
17644417767
-
Heterozygous mutations in the LDL receptor-related protein 5 (LRP5) gene are associated with primary osteoporosis in children
-
Hartikka H, Makitie O, Mannikko M, Doria AS, Daneman A, Cole WG, Ala-Kokko L, Sochett EB. Heterozygous mutations in the LDL receptor-related protein 5 (LRP5) gene are associated with primary osteoporosis in children. J Bone Miner Res. 2005;20:783-9.
-
(2005)
J Bone Miner Res
, vol.20
, pp. 783-789
-
-
Hartikka, H.1
Makitie, O.2
Mannikko, M.3
Doria, A.S.4
Daneman, A.5
Cole, W.G.6
Ala-Kokko, L.7
Sochett, E.B.8
-
26
-
-
13444295117
-
Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6
-
Holmen SL, Giambernardi TA, Zylstra CR, Buckner-Berghuis BD, Resau JH, Hess JF, Glatt V, Bouxsein ML, Ai M, Warman ML, Williams BO. Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6. J Bone Miner Res. 2004;19:2033-40.
-
(2004)
J Bone Miner Res
, vol.19
, pp. 2033-2040
-
-
Holmen, S.L.1
Giambernardi, T.A.2
Zylstra, C.R.3
Buckner-Berghuis, B.D.4
Resau, J.H.5
Hess, J.F.6
Glatt, V.7
Bouxsein, M.L.8
Ai, M.9
Warman, M.L.10
Williams, B.O.11
-
27
-
-
12144288372
-
Mutations in the LRP5 or FZD4 underlie the common familial exudative vitreoretinopathy locus on chromosome 11q
-
Toomes C, Bottomley H, Jackson RM, Towns KV, Scott S, Mackey DA, Craig JE, Jiang L, Yang Z, Trembath R, Woodruff G, Gregory-Evans CY, Gregory-Evans K, Parker MJ, Black GCM, Downey LM, Zhang K, Inglehearn CF. Mutations in the LRP5 or FZD4 underlie the common familial exudative vitreoretinopathy locus on chromosome 11q. Am J Hum Genet. 2004;74:721-30.
-
(2004)
Am J Hum Genet
, vol.74
, pp. 721-730
-
-
Toomes, C.1
Bottomley, H.2
Jackson, R.M.3
Towns, K.V.4
Scott, S.5
Mackey, D.A.6
Craig, J.E.7
Jiang, L.8
Yang, Z.9
Trembath, R.10
Woodruff, G.11
Gregory-Evans, C.Y.12
Gregory-Evans, K.13
Parker, M.J.14
Black, G.C.M.15
Downey, L.M.16
Zhang, K.17
Inglehearn, C.F.18
-
28
-
-
0025965687
-
Signs, complications, and platelet aggregation in familial exudative vitreoretinopathy
-
van Nouhuys CE. Signs, complications, and platelet aggregation in familial exudative vitreoretinopathy. Am J Ophthalmol. 1991;111:34-41.
-
(1991)
Am J Ophthalmol
, vol.111
, pp. 34-41
-
-
Van Nouhuys, C.E.1
-
29
-
-
33645457326
-
Osteoporosis pseudoglioma syndrome: 4 Siblings with a compound heterozygote LRP5 mutation
-
Streeten EA, Puffenberger E, Morton H, McBride D. Osteoporosis pseudoglioma syndrome: 4 siblings with a compound heterozygote LRP5 mutation. J Bone Miner Res. 2004;19 (Suppl 1):S182.
-
(2004)
J Bone Miner Res
, vol.19
, Issue.1 SUPPL.
-
-
Streeten, E.A.1
Puffenberger, E.2
Morton, H.3
McBride, D.4
-
30
-
-
33645455914
-
A family with osteoporosis-pseudoglioma syndrome (OPG) due to compound heterozygous mutation of the LRP5 gene
-
Jin LY, Lau HHL, Smith DK, Lau KS, Cheung PT, Kwan EYW, Low L, Chan V, Kung AWC. A family with osteoporosis-pseudoglioma syndrome (OPG) due to compound heterozygous mutation of the LRP5 gene. J Bone Miner Res. 2004;19 (Suppl 1):S129.
-
(2004)
J Bone Miner Res
, vol.19
, Issue.1 SUPPL.
-
-
Jin, L.Y.1
Lau, H.H.L.2
Smith, D.K.3
Lau, K.S.4
Cheung, P.T.5
Kwan, E.Y.W.6
Low, L.7
Chan, V.8
Kung, A.W.C.9
-
31
-
-
27544475338
-
OPPG and HBM disease-causing missense mutations in LRP5 have opposite effects on Wnt signaling
-
Ai M, Schelling D, Warman ML. OPPG and HBM disease-causing missense mutations in LRP5 have opposite effects on Wnt signaling. J Bone Miner Res. 2004;19 (Suppl 1):S80.
-
(2004)
J Bone Miner Res
, vol.19
, Issue.1 SUPPL.
-
-
Ai, M.1
Schelling, D.2
Warman, M.L.3
-
32
-
-
33645458664
-
Functional modulation of LRP5-Wnt-Dkk1 activity by various mutations in LRP5 beta-propeller 1
-
Bhat BM, Allen KM, Graham J, Liu W, Morales A, Anisowicz A, Lam H, McCauley C, Coleburn V, Cain M, Fortier W, Wang H, Bex FJ, Yaworsky P. Functional modulation of LRP5-Wnt-Dkk1 activity by various mutations in LRP5 beta-propeller 1. J Bone Miner Res. 2003;18(suppl A):S46.
-
(2003)
J Bone Miner Res
, vol.18
, Issue.SUPPL. A
-
-
Bhat, B.M.1
Allen, K.M.2
Graham, J.3
Liu, W.4
Morales, A.5
Anisowicz, A.6
Lam, H.7
McCauley, C.8
Coleburn, V.9
Cain, M.10
Fortier, W.11
Wang, H.12
Bex, F.J.13
Yaworsky, P.14
-
33
-
-
0035902050
-
LDL-receptor-related protein 6 is a receptor for Dickkopf proteins
-
Mao B, Wu W, Li Y, Hoppe D, Stannek P, Glinka A, Niehrs C. LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. Nature. 2001;411:321-5.
-
(2001)
Nature
, vol.411
, pp. 321-325
-
-
Mao, B.1
Wu, W.2
Li, Y.3
Hoppe, D.4
Stannek, P.5
Glinka, A.6
Niehrs, C.7
-
34
-
-
0037144481
-
A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta-catenin-dependent signaling
-
Holmen SL, Salic A, Zylstra CR, Kirschner MW, Williams BO. A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta-catenin-dependent signaling. J Biol Chem. 2002;277:34727-35.
-
(2002)
J Biol Chem
, vol.277
, pp. 34727-34735
-
-
Holmen, S.L.1
Salic, A.2
Zylstra, C.R.3
Kirschner, M.W.4
Williams, B.O.5
-
35
-
-
0242704649
-
Wnt/Wingless signaling through beta-catenin requires the function of both LRP/Arrow and frizzled classes of receptors
-
Schweizer L, Varmus H. Wnt/Wingless signaling through beta-catenin requires the function of both LRP/Arrow and frizzled classes of receptors. BMC Cell Biol. 2003;4(1):4.
-
(2003)
BMC Cell Biol
, vol.4
, Issue.1
, pp. 4
-
-
Schweizer, L.1
Varmus, H.2
-
36
-
-
0141725483
-
Wise, a context-dependent activator and inhibitor of Wnt signaling
-
Itasaki N, Jones CM, Mercurio S, Rowe A, Domingos PM, Smith JC, Krumlauf R. Wise, a context-dependent activator and inhibitor of Wnt signaling. Development. 2003;130:4295-305.
-
(2003)
Development
, vol.130
, pp. 4295-4305
-
-
Itasaki, N.1
Jones, C.M.2
Mercurio, S.3
Rowe, A.4
Domingos, P.M.5
Smith, J.C.6
Krumlauf, R.7
-
37
-
-
2442656675
-
The LRP5 high-bone-mass G171V mutation disrupts LRP5 interaction with Mesd
-
Zhang Y, Wang Y, Li X, Zhang J, Mao J, Li Z, Zheng J, Li L, Harris S, Wu D. The LRP5 high-bone-mass G171V mutation disrupts LRP5 interaction with Mesd. Mol Cell Biol. 2004;24:4677-84.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 4677-4684
-
-
Zhang, Y.1
Wang, Y.2
Li, X.3
Zhang, J.4
Mao, J.5
Li, Z.6
Zheng, J.7
Li, L.8
Harris, S.9
Wu, D.10
-
38
-
-
0037423222
-
Mesd encodes an LRP5/6 chaperone essential for specification of mouse embryonic polarity
-
Hsieh J-C, Lee L, Zhang L, Wefer S, Brown K, Rosenquist T, Holdener BC. Mesd encodes an LRP5/6 chaperone essential for specification of mouse embryonic polarity. Cell. 2003;112:355-67.
-
(2003)
Cell
, vol.112
, pp. 355-367
-
-
Hsieh, J.-C.1
Lee, L.2
Zhang, L.3
Wefer, S.4
Brown, K.5
Rosenquist, T.6
Holdener, B.C.7
-
39
-
-
0037423256
-
Boca, an endoplasmic reticulum protein required for wingless signaling and trafficking of LDL receptor family members in Drosophila
-
Culi J, Mann RS. Boca, an endoplasmic reticulum protein required for wingless signaling and trafficking of LDL receptor family members in Drosophila. Cell. 2003;112:343-54.
-
(2003)
Cell
, vol.112
, pp. 343-354
-
-
Culi, J.1
Mann, R.S.2
-
40
-
-
18244427021
-
Low-density lipoprotein receptor-related protein-5 binds to axin and regulates the canonical Wnt signaling pathway
-
Mao J, Wang J, Liu B, Pan W, Farr G, Flynn C, Yuan H, Takada S, Kimelman D, Li L, Wu D. Low-density lipoprotein receptor-related protein-5 binds to axin and regulates the canonical Wnt signaling pathway. Mol Cell. 2001;7:801-9.
-
(2001)
Mol Cell
, vol.7
, pp. 801-809
-
-
Mao, J.1
Wang, J.2
Liu, B.3
Pan, W.4
Farr, G.5
Flynn, C.6
Yuan, H.7
Takada, S.8
Kimelman, D.9
Li, L.10
Wu, D.11
-
41
-
-
3042848976
-
Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize beta-catenin independently of Frizzled proteins
-
Brennan K, Gonzalez-Sancho JM, Castelo-Soccio LA, Howe LR, Brown AM. Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize beta-catenin independently of Frizzled proteins. Oncogene. 2004;23:4873-84.
-
(2004)
Oncogene
, vol.23
, pp. 4873-4884
-
-
Brennan, K.1
Gonzalez-Sancho, J.M.2
Castelo-Soccio, L.A.3
Howe, L.R.4
Brown, A.M.5
-
42
-
-
2442680430
-
Wnt proteins induce dishevelled phosphorylation via an LRP5/6 independent mechanism, irrespective of their ability to stabilize beta-catenin
-
Gonzalez-Sancho JM, Brennan KR, Castelo-Soccio LA, Brown AM. Wnt proteins induce dishevelled phosphorylation via an LRP5/6 independent mechanism, irrespective of their ability to stabilize beta-catenin. Mol Cell Biol. 2004;24:4757-68.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 4757-4768
-
-
Gonzalez-Sancho, J.M.1
Brennan, K.R.2
Castelo-Soccio, L.A.3
Brown, A.M.4
-
43
-
-
0025250145
-
NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor
-
Chen WJ, Goldstein JL, Brown MS. NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor. J Biol Chem. 1990;265:3116-23.
-
(1990)
J Biol Chem
, vol.265
, pp. 3116-3123
-
-
Chen, W.J.1
Goldstein, J.L.2
Brown, M.S.3
-
44
-
-
1642564513
-
A mechanism for Wnt coreceptor activation
-
Tamai K, Zeng X, Liu C, Zhang X, Harada Y, Chang Z, He X. A mechanism for Wnt coreceptor activation. Mol Cell. 2004;13:149-56.
-
(2004)
Mol Cell
, vol.13
, pp. 149-156
-
-
Tamai, K.1
Zeng, X.2
Liu, C.3
Zhang, X.4
Harada, Y.5
Chang, Z.6
He, X.7
-
45
-
-
17044462159
-
Interaction between LRP5 and Frat1 mediates the activation of the Wnt canonical pathway
-
Hay E, Fauchen C, Suc-Royer I, Touitou R, Stiot V, Vayssiere B, Baron R, Roman SR, Rawadi G. Interaction between LRP5 and Frat1 mediates the activation of the Wnt canonical pathway. J Biol Chem. 2005;280(14):13616-23.
-
(2005)
J Biol Chem
, vol.280
, Issue.14
, pp. 13616-13623
-
-
Hay, E.1
Fauchen, C.2
Suc-Royer, I.3
Touitou, R.4
Stiot, V.5
Vayssiere, B.6
Baron, R.7
Roman, S.R.8
Rawadi, G.9
-
46
-
-
0034727078
-
An LDL-receptor-related protein mediates Wnt signalling in mice
-
Pinson KI, Brennan J, Monkley S, Avery BJ, Skarnes WC. An LDL-receptor-related protein mediates Wnt signalling in mice. Nature. 2000;407:535-8.
-
(2000)
Nature
, vol.407
, pp. 535-538
-
-
Pinson, K.I.1
Brennan, J.2
Monkley, S.3
Avery, B.J.4
Skarnes, W.C.5
-
47
-
-
2942745406
-
Bone sensitivity to mechanical loads with the Lrp5 HBM mutation
-
Cullen DM, Akhter MP, Mace D, Johnson ML, Babij P, Recker RR. Bone sensitivity to mechanical loads with the Lrp5 HBM mutation. J Bone Miner Res. 2002;17 (suppl 1):S332.
-
(2002)
J Bone Miner Res
, vol.17
, Issue.1 SUPPL.
-
-
Cullen, D.M.1
Akhter, M.P.2
Mace, D.3
Johnson, M.L.4
Babij, P.5
Recker, R.R.6
-
48
-
-
12344316154
-
Site-specific osteopenia and decreased mechanoreactivity in Lrp5-mutant mice
-
Sawakami K, Robling AG, Pitner ND, Warden SJ, Li J, Warman ML, Turner CH. Site-specific osteopenia and decreased mechanoreactivity in Lrp5-mutant mice. J Bone Miner Res. 2004;19 (Suppl 1):S38.
-
(2004)
J Bone Miner Res
, vol.19
, Issue.1 SUPPL.
-
-
Sawakami, K.1
Robling, A.G.2
Pitner, N.D.3
Warden, S.J.4
Li, J.5
Warman, M.L.6
Turner, C.H.7
-
49
-
-
2342529785
-
Polymorphisms in the low-density lipoprotein receptor-related protein 5(LRP5) gene are associated with variation in vertebral bone mass vertebral bone size, and stature in whites
-
Ferrari S, Deutsch S, Choudhury U, Chevalley T, Bonjour J, Dermitzakis E, Rizzoli R, Antonarakis S. Polymorphisms in the low-density lipoprotein receptor-related protein 5(LRP5) gene are associated with variation in vertebral bone mass vertebral bone size, and stature in whites. Am J Hum Genet. 2004;74:866-75.
-
(2004)
Am J Hum Genet
, vol.74
, pp. 866-875
-
-
Ferrari, S.1
Deutsch, S.2
Choudhury, U.3
Chevalley, T.4
Bonjour, J.5
Dermitzakis, E.6
Rizzoli, R.7
Antonarakis, S.8
-
50
-
-
14844298409
-
Influence of LRP5 polymorphisms on normal variation in BMD
-
Koay MA, Woon PY, Zhang Y, Miles LJ, Duncan EL, Ralston SH, Compston JE, Cooper C, Keen R, Langdahl BL, MacLelland A, O'Riordan J, Pols HA, Reid DM, Uitterlinden AG, Wass JAH, Brown MA. Influence of LRP5 polymorphisms on normal variation in BMD. J Bone Miner Res. 2004;19:1619-27.
-
(2004)
J Bone Miner Res
, vol.19
, pp. 1619-1627
-
-
Koay, M.A.1
Woon, P.Y.2
Zhang, Y.3
Miles, L.J.4
Duncan, E.L.5
Ralston, S.H.6
Compston, J.E.7
Cooper, C.8
Keen, R.9
Langdahl, B.L.10
MacLelland, A.11
O'Riordan, J.12
Pols, H.A.13
Reid, D.M.14
Uitterlinden, A.G.15
Wass, J.A.H.16
Brown, M.A.17
-
51
-
-
6344241957
-
Autosomal recessive familial exudative vitreoretinopathy is associated with mutations in LRP5
-
Jiao X, Ventruto V, Trese MT, Shastry BS, Hejtmancik JF. Autosomal recessive familial exudative vitreoretinopathy is associated with mutations in LRP5. Am J Hum Genet. 2004;75:878-84.
-
(2004)
Am J Hum Genet
, vol.75
, pp. 878-884
-
-
Jiao, X.1
Ventruto, V.2
Trese, M.T.3
Shastry, B.S.4
Hejtmancik, J.F.5
-
52
-
-
14444268540
-
Autosomal recessive familial exudative vitreoretinopathy: Evidence for genetic heterogeneity
-
de Crecchio G, Simonelli F, Nunziata G, Mazzeo S, Greco GM, Rinaldi E, Ventruto V, Ciccodicola A, Miano MG, Testa F, Curci A, D'Urso MM, Rinaldi MM, Cavaliere ML, Castellucio P. Autosomal recessive familial exudative vitreoretinopathy: evidence for genetic heterogeneity. Clin Genet. 1998;54:315-20.
-
(1998)
Clin Genet
, vol.54
, pp. 315-320
-
-
De Crecchio, G.1
Simonelli, F.2
Nunziata, G.3
Mazzeo, S.4
Greco, G.M.5
Rinaldi, E.6
Ventruto, V.7
Ciccodicola, A.8
Miano, M.G.9
Testa, F.10
Curci, A.11
D'Urso, M.M.12
Rinaldi, M.M.13
Cavaliere, M.L.14
Castellucio, P.15
-
53
-
-
0037422571
-
Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion
-
U S A
-
Fujino T, Asaba MJ, Kang M, Ikeda Y, Sone H, Takads S, Kim D, Loka R, Ono M, Tomoyori H, Okubo M, Murase T, Kmataki A, Yamamoto J, Magoori K, Takahashi S, Miyamoto Y, Oishi H, Nose M, Okazaki M, Usui S, Imaizumi K, Yanagisawa M, Sakai J, Yamamoto T. Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion. Proc Natl Acad Sci U S A. 2003;100:229-34.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 229-234
-
-
Fujino, T.1
Asaba, M.J.2
Kang, M.3
Ikeda, Y.4
Sone, H.5
Takads, S.6
Kim, D.7
Loka, R.8
Ono, M.9
Tomoyori, H.10
Okubo, M.11
Murase, T.12
Kmataki, A.13
Yamamoto, J.14
Magoori, K.15
Takahashi, S.16
Miyamoto, Y.17
Oishi, H.18
Nose, M.19
Okazaki, M.20
Usui, S.21
Imaizumi, K.22
Yanagisawa, M.23
Sakai, J.24
Yamamoto, T.25
more..
-
54
-
-
17644376821
-
Oropharyngeal skeletal disease accompanying high bone mass and novel LRP5 mutation
-
Rickels MR, Zhang X, Mumm S, Whyte M. Oropharyngeal skeletal disease accompanying high bone mass and novel LRP5 mutation. J Bone Miner Res. 2005;20:878-85.
-
(2005)
J Bone Miner Res
, vol.20
, pp. 878-885
-
-
Rickels, M.R.1
Zhang, X.2
Mumm, S.3
Whyte, M.4
-
55
-
-
0031575703
-
Familial exudative vitreoretinopathy: Further evidence for genetic heterogeneity
-
Shastry BS, Trese MT. Familial exudative vitreoretinopathy: further evidence for genetic heterogeneity. Am J Med Genet. 1997;69:217-8.
-
(1997)
Am J Med Genet
, vol.69
, pp. 217-218
-
-
Shastry, B.S.1
Trese, M.T.2
-
56
-
-
17544401107
-
Seven novel sequence variants in the human low density lipoprotein receptor related protein 5 (LRP5) gene
-
Okubo M, Horinishi A, Kim DH, Yamamoto TT, Murase T. Seven novel sequence variants in the human low density lipoprotein receptor related protein 5 (LRP5) gene. Hum Mutat. 2002;19:186-8.
-
(2002)
Hum Mutat
, vol.19
, pp. 186-188
-
-
Okubo, M.1
Horinishi, A.2
Kim, D.H.3
Yamamoto, T.T.4
Murase, T.5
-
57
-
-
3042752105
-
Association between bone mineral density and LDL receptor-related protein 5 gene polymorphisms in young Korean men
-
Koh JM, Jung MH, Hong JS, Park HJ, Chang JS, Shin HD, Kim SY, Kim GS. Association between bone mineral density and LDL receptor-related protein 5 gene polymorphisms in young Korean men. J Korean Med Sci. 2004;19:407-12.
-
(2004)
J Korean Med Sci
, vol.19
, pp. 407-412
-
-
Koh, J.M.1
Jung, M.H.2
Hong, J.S.3
Park, H.J.4
Chang, J.S.5
Shin, H.D.6
Kim, S.Y.7
Kim, G.S.8
-
58
-
-
12144287023
-
LRP5, low-density-lipoprotein-receptor-related protein 5, is a determinant for bone mineral density
-
Mizuguchi T, Furuta I, Watanbe Y, Tsukamoto K, Tomita H, Tsujihata M, Ohta T, Kishino T, Matsumoto N, Minakami H, Niikawa N, Yoshiura K. LRP5, low-density-lipoprotein-receptor-related protein 5, is a determinant for bone mineral density. J Hum Genet. 2004;49:80-6.
-
(2004)
J Hum Genet
, vol.49
, pp. 80-86
-
-
Mizuguchi, T.1
Furuta, I.2
Watanbe, Y.3
Tsukamoto, K.4
Tomita, H.5
Tsujihata, M.6
Ohta, T.7
Kishino, T.8
Matsumoto, N.9
Minakami, H.10
Niikawa, N.11
Yoshiura, K.12
|