Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize β-catenin independently of Frizzled proteins

Oncogene

Volumn 23, Issue 28, 2004, Pages 4873-4884

  Brennan, Keith ^a,b,c   Gonzalez Sancho, José M ^a,b   Castelo Soccio, Leslie A ^a,b   Howe, Louise R ^a,b   Brown, Anthony M C ^a,b  

^a ROCKEFELLER UNIVERSITY   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

catenin; Arrow; Frizzled; LRP6; Receptors; Wnt signaling

Indexed keywords

BETA CATENIN; CELL SURFACE RECEPTOR; FRIZZLED PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; ONCOPROTEIN; UNCLASSIFIED DRUG; CTNNB1 PROTEIN, HUMAN; CYTOSKELETON PROTEIN; LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; LIPOPROTEIN RECEPTOR-RELATED PROTEIN 6; LOW DENSITY LIPOPROTEIN RECEPTOR; LUCIFERASE; PRIMER DNA; PROTEIN; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN STABILITY; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; ANIMAL; CELL LINE; DROSOPHILA MELANOGASTER; GENE DELETION; GENETIC TRANSFECTION; GENETICS; NUCLEOTIDE SEQUENCE; ONCOGENE; PHYSIOLOGY; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALIA;

ANIMALS; BASE SEQUENCE; BETA CATENIN; CELL LINE; CYTOSKELETAL PROTEINS; DNA PRIMERS; DROSOPHILA MELANOGASTER; FRIZZLED RECEPTORS; GENES, REPORTER; HUMANS; LDL-RECEPTOR RELATED PROTEINS; LUCIFERASES; ONCOGENES; PROTEINS; RECEPTORS, LDL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE DELETION; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSFECTION;

EID: 3042848976     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207642     Document Type: Article

References (60)

1. Bafico A, Liu G, Yaniv A, Gazit A and Aaronson SA. (2001). Nat. Cell Biol., 3, 683-686.
2. Bhanot P, Brink M, Harryman Samos C, Hsieh J-C, Wang Y-S, Macke JP, Andrew D, Nathans J and Nusse R. (1996). Nature, 382, 225-230.
3. Bhanot P, Fish M, Jemison JA, Nusse R, Nathans J and Cadigan KM. (1999). Development, 126, 4175-4186.
4. Binari RC, Staveley BE, Johnson WA, Godavarti R, Sasisekharan R and Manoukian AS. (1997). Development, 124, 2623-2632.
5. Boutros M, Mihaly J, Bouwmeester T and Mlodzik M. (2000). Science, 288, 1825-1828.
6. Boyden LM, Mao J, Belsky J, Mitzner L, Farhi A, Mitnick MA, Wu D, Insogna K and Lifton RP. (2002). N. Engl. J. Med., 346, 1513-1521.
7. Bradley RS and Brown AMC. (1995). Mol. Cell. Biol., 15, 4616-4622.
8. Brown SD, Twells RCJ, Hey PJ, Cox RD, Levy ER, Soderman AR, Metzker ML, Caskey CT, Todd JA and Hess JF. (1998). Biochem. Biophys. Res. Commun., 248, 879-888.
9. Cadigan KM and Nusse R. (1997). Genes Dev., 11, 3286-3305.
10. Chan SDH, Karpf DB, Fowlkes ME, Hooks M, Bradley MS, Vuong V, Bambino T, Liu MYC, Arnaud CD, Strewler GJ and Nissenson RA. (1992). J. Biol. Chem., 267, 25202-25207.
11. Chelly J, Concordet JP, Kaplan JC and Kahn A. (1989). Proc. Natl. Acad. Sci. USA, 86, 2617-2621.
12. Chen CM and Struhl G. (1999). Development, 126, 5441-5452.
13. Deardorff MA, Tan C, Conrad LJ and Klein PS. (1998). Development, 125, 2687-2700.
14. Deardorff MA, Tan C, Saint-Jeannet JP and Klein PS. (2001). Development, 128, 3655-3663.
15. Eastman Q and Grosschedl R. (1999). Curr. Opin. Cell Biol., 11, 233-240.
16. Gazit A, Yaniv A, Bafico A, Pramila T, Igarashi M, Kitajewski J and Aaronson SA. (1999). Oncogene, 18, 5959-5966.
17. Giarre M, Semenov MV and Brown AMC. (1998). Ann. NY Acad. Sci., 857, 43-55.
18. He X, Saint Jeannet J-P, Wang Y, Nathans J, Dawid I and Varmus H. (1997). Science, 275, 1652-1654.
19. Hecht A and Kemler R. (2000). EMBO Rep., 1, 24-28.
20. Holmen SL, Salic A, Zylstra CR. Kirschner MW and Williams BO. (2002). J. Biol. Chem., 277, 34727-34735.
21. Howe LR, Crawford HC, Subbaramaiah K, Hassell JA, Dannenberg AJ and Brown AMC. (2001). J. Biol. Chem., 276, 20108-20115.
22. Hsieh JC, Rattner A, Smallwood PM and Nathans J. (1999). Proc. Nat. Acad Sci. USA, 96, 3546-3551.
23. Huelsken J and Behrens J. (2002). J. Cell Sci., 115, 3977-3978.
24. Huelsken J and Birchmeier W. (2001). Curr. Opin. Genet. Dev., 11, 547-553.
25. Hussain MM, Strickland DK and Bakillah A. (1999). Annu. Rev. Nutr., 19, 141-172.
26. Kaplan JC, Kahn A and Chelly J. (1992). Hum. Mutat., 1, 357-360.
27. Karasawa T, Yokokura H, Kitajewski J and Lombroso PJ. (2002). J. Biolo. Chem, 277, 37479-37486.
28. Leyns L, Bouwmeester T, Kim SH, Piccolo S and DeRobertis EM. (1997). Cell, 88, 747-756.
29. Lin X and Perrimon N. (1999). Nature, 400, 281-284.
30. Little RD, Carulli JP, Del Mastro RG, Dupuis J and Osborne M. (2002). Am. J. Hum. Genet., 70, 11-19.
31. Liu G, Bafico A, Harris VK and Aaronson SA. (2003). Mol. Cell. Biol., 23, 5825-5835.
32. Longo KA, Kennell JA, Ochocinska MJ, Ross SE, Wright WS and MacDougald OA. (2002). J. Biol. Chem., 277, 38239-38244.
33. Mao B, Wu W, Davidson G, Marhold J, Li M, Mechler BM, Delius H, Hoppe D, Stannek P, Walter C, Glinka A and Niehrs C. (2002). Nature, 417, 664-667.
34. Mao B, Wu W, Li Y, Hoppe D, Stannek P, Glinka A and Niehrs C. (2001a). Nature, 411, 321-325.
35. Mao J, Wang J, Liu B, Pan W, Farr III GH, Flynn C, Yuan H, Takada S, Kimelman D, Li L and Wu D. (2001b). Mol. Cell, 7, 801-809.
36. Mumm JS and Kopan R. (2000). Dev. Biol., 228, 151-165.
37. Nusse R, Samos CH, Brink M, Willert K, Cadigan KM, Wodarz A, Fish M and Rulifson E. (1997). Cold Spring Harb. Symp. Quant. Biol., 62, 185-190.
38. Nusse R and Varmus HE. (1992). Cell, 69, 1073-1087.
39. Pinson KI, Brennan J, Monkley S, Avery BJ and Skarnes WC. (2000). Nature, 407, 535-538.
40. Polakis P. (2000). Genes Dev., 14, 1837-1851.
41. Sato A, Kojima T, Ui-Tei K, Miyata Y and Saigo K. (1999). Development, 126, 4421-4430.
42. Schlessinger J. (2000). Cell, 103, 211-225.
43. Schweizer L and Varmus H. (2003). BMC Cell Biol., 4, 4.
44. Semenov MV, Tamai K, Brott BK, Kuhl M, Sokol S and He X. (2001). Curr. Biol., 11, 951-961.
45. Shimizu H, Julius MA, Zheng Z, Giarre M, Brown AMC and Kitajewski J. (1997). Cell Growth Differ., 8, 1349-1358.
46. Tamai K, Semenov M, Kato Y, Spokony R, Liu C, Katsuyama Y, Hess F, Saint-Jeannet JP and He X. (2000). Nature, 407, 530-535.
47. Tamai K, Zeng X, Liu C, Zhang X, Harada Y, Chang Z and He X. (2004). Mol. Cell 13, 149-156.
48. Tolwinski NS, Wehrli M, Rives A, Erdeniz N, DiNardo S and Wieschaus E. (2003). Dev. Cell, 4, 407-418.
49. Toyofuku T, Hong Z, Kuzuya T, Tada M and Hori M. (2000). J. Cell Blol., 150, 225-241.
50. Tsuda M, Kamimura K, Nakato H, Archer M, Staatz W, Fox B, Humphrey M, Olson S, Futch T, Kaluza V, Siegfried E, Stam L and Selleck SB. (1999). Nature, 400, 276-280.
51. Umbhauer M, Djiane A, Goisset C, Penzo-Mendez A, Riou J-F, Boucaut J-C and Shi D-L. (2000). EMBO J., 19, 4944-4954.
52. Uren A, Reichsman F, Anest V, Taylor WG, Muraiso K, Bottaro DP, Cumberledge S and Rubin JS. (2000). J. Biol. Chem., 275, 4374-4382.
53. Uusitalo M, Heikkila M and Vainio S. (1999). Exp. Cell Res., 253, 336-348.
54. van de Wetering M, Cavallo R, Dooijes D, van Beest M, van Es J, Loureiro J, Ypma A, Hursh D, Jones T, Bejsovec A, Peifer M, Mortin M and Clevers H. (1997). Cell, 88, 789-799.
55. Wang SW, Krinks M, Lin KM, Luyten FP and Moos M. (1997). Cell, 88, 757-766.
56. Wang YS, Macke JP, Abella BS, Andreasson K, Worley P, Gilbert DJ, Copeland NG, Jenkins NA and Nathans J. (1996). J. Biol. Chem., 271, 4468-4476.
57. Weeraratna AT, Jiang Y, Hostetter G, Rosenblatt K, Duray P, Bittner M and Trent JM. (2002). Cancer Cell, 1, 279-288.
58. Wehrli M, Dougan ST, Caldwell K, O'Keefe L, Schwartz S, Vaizel-Ohayon D, Schejter E, Tomlinson A and DiNardo S. (2000). Nature, 407, 527-530.
59. Yang-Snyder J, Miller JR, Brown JD, Lai CJ and Moon RT. (1996). Curr. Biol., 6, 1302-1306.
60. You Z, Saims D, Chen S, Zhang Z, Guttridge DC, Guan KL, MacDougald OA, Brown AMC, Evan G, Kitajewski J and Wang CY. (2002). J. Cell Biol., 157, 429-440.