Heterozygous mutations in the LDL receptor-related protein 5 (LRP5) gene are associated with primary osteoporosis in children

Journal of Bone and Mineral Research

Volumn 20, Issue 5, 2005, Pages 783-789

  Hartikka, Heini ^a   Mäkitie, Outi ^b,c   Männikkö, Minna ^a   Doria, Andrea S ^b   Daneman, Alan ^b   Cole, William G ^b   Ala Kokko, Leena ^a,d,e   Sochett, Etienne B ^b  

^a UNIVERSITY OF OULU   (Finland)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^d TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^e OULU UNIVERSITY HOSPITAL   (Finland)

Author keywords

Bone; Collagen; Low density lipoprotein receptor related protein 5; Osteogenesis imperfecta; Osteoporosis

Indexed keywords

COLLAGEN TYPE 1; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5;

ADOLESCENT; ARTICLE; BONE DISEASE; BONE FRAGILITY; BONE GROWTH; CHILD; CONTROLLED STUDY; FEMALE; FRAMESHIFT MUTATION; GENE; GENE MUTATION; GENE TARGETING; GENETIC ASSOCIATION; GENETIC CODE; HETEROZYGOSITY; HUMAN; LRP5 GENE; MAJOR CLINICAL STUDY; MALE; MISSENSE MUTATION; OSTEOGENESIS IMPERFECTA; OSTEOPOROSIS; PHENOTYPE; PHYSICAL ACTIVITY; RECEPTOR GENE;

ADOLESCENT; CHILD; COLLAGEN; COLLAGEN TYPE I; FEMALE; FRAMESHIFT MUTATION; HETEROZYGOTE; HUMANS; LDL-RECEPTOR RELATED PROTEINS; MALE; MODELS, GENETIC; MUTATION; MUTATION, MISSENSE; OSTEOGENESIS IMPERFECTA; OSTEOPOROSIS; PHENOTYPE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; VARIATION (GENETICS);

EID: 17644417767     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/JBMR.050101     Document Type: Article

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