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Volumn 28, Issue 1-2, 2006, Pages 141-154

Primary porcine proximal tubular cells as a model for transepithelial drug transport in human kidney

Author keywords

In vitro; Porcine; Primary cultures; Proximal tubular cells; Transporters

Indexed keywords

ESTRONE SULFATE; GLYCYLSARCOSINE; INDOMETACIN; MEMBRANE PROTEIN; MESSENGER RNA; METHOTREXATE; ORGANIC ANION TRANSPORTER 1; ORGANIC CATION TRANSPORTER 1; PENICILLIN G; PHLORIZIN; POLYCYCLIC AROMATIC HYDROCARBON; PROBENECID; PROTEIN ABCB1; PROTEIN ABCC1; PROTEIN ABCC2; PROTEIN SLC15A1; PROTEIN SLC15A2; PROTEIN SLC22A6; PROTEIN SLC22A8; PROTEIN SLC4A4; PROTEIN SLC5A1; PROTEIN SLC5A2; UNCLASSIFIED DRUG; VERLUKAST;

EID: 33644912888     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2006.01.009     Document Type: Article
Times cited : (24)

References (64)
  • 3
    • 0037373848 scopus 로고    scopus 로고
    • Effects of oral adsorbent on gene expression profile in uremic rat kidney: CDNA array analysis
    • I. Aoyama, A. Enomoto, and T. Niwa Effects of oral adsorbent on gene expression profile in uremic rat kidney: cDNA array analysis Am. J. Kidney Dis. 41 2003 S8 S14
    • (2003) Am. J. Kidney Dis. , vol.41
    • Aoyama, I.1    Enomoto, A.2    Niwa, T.3
  • 5
    • 0038639696 scopus 로고    scopus 로고
    • RT-PCR-based evidence for the in vivo stimulation of renal tubular p-aminohippurate (PAH) transport by triiodothyronine (T3) or dexamethasone (DEXA) in kidney tissue of immature and adult rats
    • A. Bahn, A. Hauss, D. Appenroth, D. Ebbinghaus, Y. Hagos, P. Steinmetzer, G. Burckhardt, and C. Fleck RT-PCR-based evidence for the in vivo stimulation of renal tubular p-aminohippurate (PAH) transport by triiodothyronine (T3) or dexamethasone (DEXA) in kidney tissue of immature and adult rats Exp. Toxicol. Pathol. 54 2003 367 373
    • (2003) Exp. Toxicol. Pathol. , vol.54 , pp. 367-373
    • Bahn, A.1    Hauss, A.2    Appenroth, D.3    Ebbinghaus, D.4    Hagos, Y.5    Steinmetzer, P.6    Burckhardt, G.7    Fleck, C.8
  • 6
    • 28444481386 scopus 로고    scopus 로고
    • Development of a fluorescence-based assay for screening of modulators of human organic anion transporter 1B3 (OATP1B3)
    • C. Baldes, P. Koenig, D. Neumann, H.P. Lenhof, O. Kohlbacher, and C.M. Lehr Development of a fluorescence-based assay for screening of modulators of human organic anion transporter 1B3 (OATP1B3) Eur. J. Pharm. Biopharm. 62 2005 39 43
    • (2005) Eur. J. Pharm. Biopharm. , vol.62 , pp. 39-43
    • Baldes, C.1    Koenig, P.2    Neumann, D.3    Lenhof, H.P.4    Kohlbacher, O.5    Lehr, C.M.6
  • 7
    • 21344447788 scopus 로고    scopus 로고
    • Characterization of the ATPase activity of human ATP-binding cassette transporter-2 (ABCA2)
    • V. Beljanski, A. Soulika, J.M. Tucker, D.M. Townsend, W. Davis Jr., and K.D. Tew Characterization of the ATPase activity of human ATP-binding cassette transporter-2 (ABCA2) In Vivo 19 2005 657 660
    • (2005) In Vivo , vol.19 , pp. 657-660
    • Beljanski, V.1    Soulika, A.2    Tucker, J.M.3    Townsend, D.M.4    Davis Jr., W.5    Tew, K.D.6
  • 8
    • 0035039326 scopus 로고    scopus 로고
    • Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney
    • S.H. Cha, T. Sekine, J.I. Fukushima, Y. Kanai, Y. Kobayashi, T. Goya, and H. Endou Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney Mol. Pharmacol. 59 2001 1277 1286
    • (2001) Mol. Pharmacol. , vol.59 , pp. 1277-1286
    • Cha, S.H.1    Sekine, T.2    Fukushima, J.I.3    Kanai, Y.4    Kobayashi, Y.5    Goya, T.6    Endou, H.7
  • 9
    • 15344341734 scopus 로고    scopus 로고
    • Differential interaction of 3-hydroxy-3-methylglutaryl-coa reductase inhibitors with ABCB1, ABCC2, and OATP1B1
    • C. Chen, R.J. Mireles, S.D. Campbell, J. Lin, J.B. Mills, J.J. Xu, and T.A. Smolarek Differential interaction of 3-hydroxy-3-methylglutaryl-coa reductase inhibitors with ABCB1, ABCC2, and OATP1B1 Drug. Metab. Dispos. 33 2005 537 546
    • (2005) Drug. Metab. Dispos. , vol.33 , pp. 537-546
    • Chen, C.1    Mireles, R.J.2    Campbell, S.D.3    Lin, J.4    Mills, J.B.5    Xu, J.J.6    Smolarek, T.A.7
  • 10
    • 0033783241 scopus 로고    scopus 로고
    • Protein kinase C activation leads to dephosphorylation of occludin and tight junction permeability increase in LLC-PK1 epithelial cell sheets
    • H. Clarke, A.P. Soler, and J.M. Mullin Protein kinase C activation leads to dephosphorylation of occludin and tight junction permeability increase in LLC-PK1 epithelial cell sheets J. Cell Sci. 113 Pt 18 2000 3187 3196
    • (2000) J. Cell Sci. , vol.113 , Issue.PART 18 , pp. 3187-3196
    • Clarke, H.1    Soler, A.P.2    Mullin, J.M.3
  • 11
    • 0038701734 scopus 로고    scopus 로고
    • Claudin extracellular domains determine paracellular charge selectivity and resistance but not tight junction fibril architecture
    • O.R. Colegio, C. Van Itallie, C. Rahner, and J.M. Anderson Claudin extracellular domains determine paracellular charge selectivity and resistance but not tight junction fibril architecture Am J. Physiol. Cell Physiol. 284 2003 C1346 C1354
    • (2003) Am J. Physiol. Cell Physiol. , vol.284
    • Colegio, O.R.1    Van Itallie, C.2    Rahner, C.3    Anderson, J.M.4
  • 13
    • 0030464177 scopus 로고    scopus 로고
    • Human dipeptide transporter, hPEPT1, stably transfected into Chinese hamster ovary cells
    • K.M. Covitz, G.L. Amidon, and W. Sadee Human dipeptide transporter, hPEPT1, stably transfected into Chinese hamster ovary cells Pharm. Res. 13 1996 1631 1634
    • (1996) Pharm. Res. , vol.13 , pp. 1631-1634
    • Covitz, K.M.1    Amidon, G.L.2    Sadee, W.3
  • 15
    • 0036166635 scopus 로고    scopus 로고
    • Comparison of furosemide and vinblastine secretion from cell lines over expressing multidrug resistance protein (P-glycoprotein) and multidrug resistance-associated proteins (MRP1 and MRP2)
    • S.D. Flanagan, C.L. Cummins, M. Susanto, X. Liu, L.H. Takahashi, and L.Z. Benet Comparison of furosemide and vinblastine secretion from cell lines over expressing multidrug resistance protein (P-glycoprotein) and multidrug resistance-associated proteins (MRP1 and MRP2) Pharmacology 64 2002 126 134
    • (2002) Pharmacology , vol.64 , pp. 126-134
    • Flanagan, S.D.1    Cummins, C.L.2    Susanto, M.3    Liu, X.4    Takahashi, L.H.5    Benet, L.Z.6
  • 16
    • 0036924482 scopus 로고    scopus 로고
    • Ex vivo stimulation of renal transport of the cytostatic drugs methotrexate, cisplatin, topotecan (Hycamtin) and raltitrexed (Tomudex) by dexamethasone, T3 and EGF in intact human and rat kidney tissue and in human renal cell carcinoma
    • C. Fleck, R. Hilger, S. Jurkutat, E. Karge, U. Merkel, A. Schimske, and J. Schubert Ex vivo stimulation of renal transport of the cytostatic drugs methotrexate, cisplatin, topotecan (Hycamtin) and raltitrexed (Tomudex) by dexamethasone, T3 and EGF in intact human and rat kidney tissue and in human renal cell carcinoma Urol. Res. 30 2002 256 262
    • (2002) Urol. Res. , vol.30 , pp. 256-262
    • Fleck, C.1    Hilger, R.2    Jurkutat, S.3    Karge, E.4    Merkel, U.5    Schimske, A.6    Schubert, J.7
  • 17
    • 0032710237 scopus 로고    scopus 로고
    • Epithelial transport of anthelmintic ivermectin in a novel model of isolated proximal kidney tubules
    • G. Fricker, H. Gutmann, A. Droulle, J. Drewe, and D.S. Miller Epithelial transport of anthelmintic ivermectin in a novel model of isolated proximal kidney tubules Pharm. Res. 16 1999 1570 1575
    • (1999) Pharm. Res. , vol.16 , pp. 1570-1575
    • Fricker, G.1    Gutmann, H.2    Droulle, A.3    Drewe, J.4    Miller, D.S.5
  • 19
    • 0030892709 scopus 로고    scopus 로고
    • Interaction of anionic cephalosporins with the intestinal and renal peptide transporters PEPT 1 and PEPT 2
    • M.E. Ganapathy, P.D. Prasad, B. Mackenzie, V. Ganapathy, and F.H. Leibach Interaction of anionic cephalosporins with the intestinal and renal peptide transporters PEPT 1 and PEPT 2 Biochim. Biophys. Acta 1324 1997 296 308
    • (1997) Biochim. Biophys. Acta , vol.1324 , pp. 296-308
    • Ganapathy, M.E.1    Prasad, P.D.2    MacKenzie, B.3    Ganapathy, V.4    Leibach, F.H.5
  • 20
    • 0036692212 scopus 로고    scopus 로고
    • Renal assimilation of short chain peptides: Visualization of tubular peptide uptake
    • D.A. Groneberg, F. Doring, M. Nickolaus, H. Daniel, and A. Fischer Renal assimilation of short chain peptides: visualization of tubular peptide uptake Pharm. Res. 19 2002 1209 1214
    • (2002) Pharm. Res. , vol.19 , pp. 1209-1214
    • Groneberg, D.A.1    Doring, F.2    Nickolaus, M.3    Daniel, H.4    Fischer, A.5
  • 21
  • 22
    • 0037427972 scopus 로고    scopus 로고
    • The superfamily of organic anion transporting polypeptides
    • B. Hagenbuch, and P.J. Meier The superfamily of organic anion transporting polypeptides Biochim. Biophys. Acta 1609 2003 1 18
    • (2003) Biochim. Biophys. Acta , vol.1609 , pp. 1-18
    • Hagenbuch, B.1    Meier, P.J.2
  • 26
    • 0028803348 scopus 로고
    • Immunogold localization of high-affinity glucose transporter isoforms in normal rat kidney
    • C. Heilig, C. Zaloga, M. Lee, X. Zhao, B. Riser, F. Brosius, and P. Cortes Immunogold localization of high-affinity glucose transporter isoforms in normal rat kidney Lab. Invest. 73 1995 674 684
    • (1995) Lab. Invest. , vol.73 , pp. 674-684
    • Heilig, C.1    Zaloga, C.2    Lee, M.3    Zhao, X.4    Riser, B.5    Brosius, F.6    Cortes, P.7
  • 27
    • 3042569646 scopus 로고    scopus 로고
    • Phytoestrogens/flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance
    • Y. Imai, S. Tsukahara, S. Asada, and Y. Sugimoto Phytoestrogens/ flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance Cancer Res. 64 2004 4346 4352
    • (2004) Cancer Res. , vol.64 , pp. 4346-4352
    • Imai, Y.1    Tsukahara, S.2    Asada, S.3    Sugimoto, Y.4
  • 28
    • 0033849976 scopus 로고    scopus 로고
    • Cellular and molecular aspects of drug transport in the kidney
    • K.I. Inui, S. Masuda, and H. Saito Cellular and molecular aspects of drug transport in the kidney Kidney Int. 58 2000 944 958
    • (2000) Kidney Int. , vol.58 , pp. 944-958
    • Inui, K.I.1    Masuda, S.2    Saito, H.3
  • 29
    • 0029677194 scopus 로고    scopus 로고
    • Three-dimensional mammary primary culture model systems
    • M.M. Ip, and K.M. Darcy Three-dimensional mammary primary culture model systems J. Mammary Gland Biol. Neoplasia 1 1996 91 110
    • (1996) J. Mammary Gland Biol. Neoplasia , vol.1 , pp. 91-110
    • Ip, M.M.1    Darcy, K.M.2
  • 30
    • 0345866860 scopus 로고    scopus 로고
    • Pharmacological and physiological functions of the polyspecific organic cation transporters: OCT1, 2 and 3 (SLC22A1-3)
    • J.W. Jonker, and A.H. Schinkel Pharmacological and physiological functions of the polyspecific organic cation transporters: OCT1, 2 and 3 (SLC22A1-3) J. Pharmacol. Exp. Ther. 308 2004 2 9
    • (2004) J. Pharmacol. Exp. Ther. , vol.308 , pp. 2-9
    • Jonker, J.W.1    Schinkel, A.H.2
  • 33
    • 0037337817 scopus 로고    scopus 로고
    • Modulation of renal epithelial barrier function by mitogen-activated protein kinases (MAPKs): Mechanism of cyclosporine A-induced increase in transepithelial resistance
    • B. Kiely, G. Feldman, and M.P. Ryan Modulation of renal epithelial barrier function by mitogen-activated protein kinases (MAPKs): mechanism of cyclosporine A-induced increase in transepithelial resistance Kidney Int. 63 2003 908 916
    • (2003) Kidney Int. , vol.63 , pp. 908-916
    • Kiely, B.1    Feldman, G.2    Ryan, M.P.3
  • 34
    • 3042569768 scopus 로고    scopus 로고
    • Polyspecific organic cation transporters: Their functions and interactions with drugs
    • H. Koepsell Polyspecific organic cation transporters: their functions and interactions with drugs Trends Pharmacol. Sci. 25 2004 375 381
    • (2004) Trends Pharmacol. Sci. , vol.25 , pp. 375-381
    • Koepsell, H.1
  • 35
    • 0028135423 scopus 로고
    • Evaluation of nephrotoxicity in vitro using a suspension of highly purified porcine proximal tubular cells and characterization of the cells in primary culture
    • M. Kruidering, D.H. Maasdam, F.A. Prins, E. de Heer, G.J. Mulder, and J.F. Nagelkerke Evaluation of nephrotoxicity in vitro using a suspension of highly purified porcine proximal tubular cells and characterization of the cells in primary culture Exp. Nephrol. 2 1994 324 344
    • (1994) Exp. Nephrol. , vol.2 , pp. 324-344
    • Kruidering, M.1    Maasdam, D.H.2    Prins, F.A.3    De Heer, E.4    Mulder, G.J.5    Nagelkerke, J.F.6
  • 36
    • 0030933609 scopus 로고    scopus 로고
    • Cisplatin-induced nephrotoxicity in porcine proximal tubular cells: Mitochondrial dysfunction by inhibition of complexes I to IV of the respiratory chain
    • M. Kruidering, B. Van de Water, E. de Heer, G.J. Mulder, and J.F. Nagelkerke Cisplatin-induced nephrotoxicity in porcine proximal tubular cells: mitochondrial dysfunction by inhibition of complexes I to IV of the respiratory chain J. Pharmacol. Exp. Ther. 280 1997 638 649
    • (1997) J. Pharmacol. Exp. Ther. , vol.280 , pp. 638-649
    • Kruidering, M.1    Van De Water, B.2    De Heer, E.3    Mulder, G.J.4    Nagelkerke, J.F.5
  • 37
    • 1342344851 scopus 로고    scopus 로고
    • Transporters and renal drug elimination
    • W. Lee, and R.B. Kim Transporters and renal drug elimination Annu. Rev. Pharmacol. Toxicol. 44 2004 137 166
    • (2004) Annu. Rev. Pharmacol. Toxicol. , vol.44 , pp. 137-166
    • Lee, W.1    Kim, R.B.2
  • 38
    • 0032995116 scopus 로고    scopus 로고
    • Cloning of the human kidney PAH transporter: Narrow substrate specificity and regulation by protein kinase C
    • R. Lu, B.S. Chan, and V.L. Schuster Cloning of the human kidney PAH transporter: narrow substrate specificity and regulation by protein kinase C Am. J. Physiol. 276 1999 F295 F303
    • (1999) Am. J. Physiol. , vol.276
    • Lu, R.1    Chan, B.S.2    Schuster, V.L.3
  • 39
    • 0030475336 scopus 로고    scopus 로고
    • Multiple pathways of organic anion secretion in renal proximal tubule revealed by confocal microscopy
    • R. Masereeuw, F.G. Russel, and D.S. Miller Multiple pathways of organic anion secretion in renal proximal tubule revealed by confocal microscopy Am. J. Physiol. 271 1996 F1173 F1182
    • (1996) Am. J. Physiol. , vol.271
    • Masereeuw, R.1    Russel, F.G.2    Miller, D.S.3
  • 41
    • 0036019498 scopus 로고    scopus 로고
    • Xenobiotic export pumps, endothelin signaling, and tubular nephrotoxicants - A case of molecular hijacking
    • D.S. Miller Xenobiotic export pumps, endothelin signaling, and tubular nephrotoxicants - a case of molecular hijacking J. Biochem. Mol. Toxicol. 16 2002 121 127
    • (2002) J. Biochem. Mol. Toxicol. , vol.16 , pp. 121-127
    • Miller, D.S.1
  • 42
    • 0037338515 scopus 로고    scopus 로고
    • Sulfate conjugating and transport functions of MDCK distal tubular cells
    • K.H. Ng, B.G. Lim, and K.P. Wong Sulfate conjugating and transport functions of MDCK distal tubular cells Kidney Int. 63 2003 976 986
    • (2003) Kidney Int. , vol.63 , pp. 976-986
    • Ng, K.H.1    Lim, B.G.2    Wong, K.P.3
  • 43
    • 0035149585 scopus 로고    scopus 로고
    • Ritonavir induces P-glycoprotein expression, multidrug resistance-associated protein (MRP1) expression, and drug transporter-mediated activity in a human intestinal cell line
    • M.D. Perloff, L.L. Von Moltke, J.E. Marchand, and D.J. Greenblatt Ritonavir induces P-glycoprotein expression, multidrug resistance-associated protein (MRP1) expression, and drug transporter-mediated activity in a human intestinal cell line J. Pharm. Sci. 90 2001 1829 1837
    • (2001) J. Pharm. Sci. , vol.90 , pp. 1829-1837
    • Perloff, M.D.1    Von Moltke, L.L.2    Marchand, J.E.3    Greenblatt, D.J.4
  • 44
    • 0036406826 scopus 로고    scopus 로고
    • Influence of different chemicals on MDR-1 P-glycoprotein expression and activity in the HK-2 proximal tubular cell line
    • N. Romiti, G. Tramonti, and E. Chieli Influence of different chemicals on MDR-1 P-glycoprotein expression and activity in the HK-2 proximal tubular cell line Toxicol. Appl. Pharmacol. 183 2002 83 91
    • (2002) Toxicol. Appl. Pharmacol. , vol.183 , pp. 83-91
    • Romiti, N.1    Tramonti, G.2    Chieli, E.3
  • 45
    • 0032760225 scopus 로고    scopus 로고
    • Effects of glibenclamide on glycylsarcosine transport by the rat peptide transporters PEPT1 and PEPT2
    • K. Sawada, T. Terada, H. Saito, Y. Hashimoto, and K. Inui Effects of glibenclamide on glycylsarcosine transport by the rat peptide transporters PEPT1 and PEPT2 Br. J. Pharmacol. 128 1999 1159 1164
    • (1999) Br. J. Pharmacol. , vol.128 , pp. 1159-1164
    • Sawada, K.1    Terada, T.2    Saito, H.3    Hashimoto, Y.4    Inui, K.5
  • 48
    • 0037427941 scopus 로고    scopus 로고
    • Uptake of dipeptide and beta-lactam antibiotics by the basolateral membrane vesicles prepared from rat kidney
    • M. Sugawara, T. Ogawa, M. Kobayashi, and K. Miyazaki Uptake of dipeptide and beta-lactam antibiotics by the basolateral membrane vesicles prepared from rat kidney Biochim. Biophys. Acta 1609 2003 39 44
    • (2003) Biochim. Biophys. Acta , vol.1609 , pp. 39-44
    • Sugawara, M.1    Ogawa, T.2    Kobayashi, M.3    Miyazaki, K.4
  • 50
    • 0344484852 scopus 로고    scopus 로고
    • Glucose transporters in the transepithelial transport of glucose
    • K. Takata Glucose transporters in the transepithelial transport of glucose J. Electron. Microsc. (Tokyo) 45 1996 275 284
    • (1996) J. Electron. Microsc. (Tokyo) , vol.45 , pp. 275-284
    • Takata, K.1
  • 52
    • 0036998906 scopus 로고    scopus 로고
    • Clonal analysis of immortalized renal proximal tubule cells: Na(+)/glucose cotransport system levels are maintained despite a decline in transport function
    • M. Taub, H.J. Han, T. Rajkhowa, C. Allen, and J.H. Park Clonal analysis of immortalized renal proximal tubule cells: Na(+)/glucose cotransport system levels are maintained despite a decline in transport function Exp. Cell. Res. 281 2002 205 212
    • (2002) Exp. Cell. Res. , vol.281 , pp. 205-212
    • Taub, M.1    Han, H.J.2    Rajkhowa, T.3    Allen, C.4    Park, J.H.5
  • 54
    • 0242665742 scopus 로고    scopus 로고
    • Reversal of charge selectivity in cation or anion-selective epithelial lines by expression of different claudins
    • C.M. Van Itallie, A.S. Fanning, and J.M. Anderson Reversal of charge selectivity in cation or anion-selective epithelial lines by expression of different claudins Am. J. Physiol. Renal Physiol. 285 2003 F1078 F1084
    • (2003) Am. J. Physiol. Renal Physiol. , vol.285
    • Van Itallie, C.M.1    Fanning, A.S.2    Anderson, J.M.3
  • 55
    • 15844369734 scopus 로고    scopus 로고
    • Substrates and inhibitors of efflux proteins interfere with the MTT assay in cells and may lead to underestimation of drug toxicity
    • K.S. Vellonen, P. Honkakoski, and A. Urtti Substrates and inhibitors of efflux proteins interfere with the MTT assay in cells and may lead to underestimation of drug toxicity Eur. J. Pharm. Sci. 23 2004 181 188
    • (2004) Eur. J. Pharm. Sci. , vol.23 , pp. 181-188
    • Vellonen, K.S.1    Honkakoski, P.2    Urtti, A.3
  • 56
    • 1542270316 scopus 로고    scopus 로고
    • Mediation of annexin 1 secretion by a probenecid-sensitive ABC-transporter in rat inflamed mucosa
    • S. Wein, M. Fauroux, J. Laffitte, P. de Nadai, C. Guaini, F. Pons, and C. Comera Mediation of annexin 1 secretion by a probenecid-sensitive ABC-transporter in rat inflamed mucosa Biochem. Pharmacol. 67 2004 1195 1202
    • (2004) Biochem. Pharmacol. , vol.67 , pp. 1195-1202
    • Wein, S.1    Fauroux, M.2    Laffitte, J.3    De Nadai, P.4    Guaini, C.5    Pons, F.6    Comera, C.7
  • 57
    • 0036088569 scopus 로고    scopus 로고
    • Extracellular glutathione peroxidase is secreted basolaterally by human renal proximal tubule cells
    • J.C. Whitin, S. Bhamre, D.M. Tham, and H.J. Cohen Extracellular glutathione peroxidase is secreted basolaterally by human renal proximal tubule cells Am. J. Physiol. Renal Physiol. 283 2002 F20 F28
    • (2002) Am. J. Physiol. Renal Physiol. , vol.283
    • Whitin, J.C.1    Bhamre, S.2    Tham, D.M.3    Cohen, H.J.4
  • 59
    • 85046913913 scopus 로고    scopus 로고
    • Cloning and characterization of the rat multidrug resistance-associated protein 1
    • Z. Yang, C.S. Li, D.D. Shen, and R.J. Ho Cloning and characterization of the rat multidrug resistance-associated protein 1 AAPS PharmSci 4 2002 E15
    • (2002) AAPS PharmSci , vol.4 , pp. 15
    • Yang, Z.1    Li, C.S.2    Shen, D.D.3    Ho, R.J.4
  • 60
    • 0036842911 scopus 로고    scopus 로고
    • Structure, function, and regulation of renal organic anion transporters
    • G. You Structure, function, and regulation of renal organic anion transporters Med. Res. Rev. 22 2002 602 616
    • (2002) Med. Res. Rev. , vol.22 , pp. 602-616
    • You, G.1
  • 62
    • 3042842484 scopus 로고    scopus 로고
    • Human organic anion transporter 1 mediates cellular uptake of cysteine-S conjugates of inorganic mercury
    • R.K. Zalups, A.G. Aslamkhan, and S. Ahmad Human organic anion transporter 1 mediates cellular uptake of cysteine-S conjugates of inorganic mercury Kidney Int. 66 2004 251 261
    • (2004) Kidney Int. , vol.66 , pp. 251-261
    • Zalups, R.K.1    Aslamkhan, A.G.2    Ahmad, S.3
  • 64
    • 0346035033 scopus 로고    scopus 로고
    • Determination of thalidomide in transport buffer for Caco-2 cell monolayers by high-performance liquid chromatography with ultraviolet detection
    • S. Zhou, Y. Li, P. Kestell, and J.W. Paxton Determination of thalidomide in transport buffer for Caco-2 cell monolayers by high-performance liquid chromatography with ultraviolet detection J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 785 2003 165 173
    • (2003) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. , vol.785 , pp. 165-173
    • Zhou, S.1    Li, Y.2    Kestell, P.3    Paxton, J.W.4


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