Nutritional upregulation of p85α expression is an early molecular manifestation of insulin resistance

Diabetologia

Volumn 49, Issue 4, 2006, Pages 748-754

  Cornier, M A ^a   Bessesen, D H ^a   Gurevich, I ^a   Leitner, J W ^a   Draznin, B ^a,b  

^a DEPARTMENT OF VETERANS AFFAIRS   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Insulin resistance; Insulin signalling; Overfeeding; Phosphatidylinositol 3 kinase

Indexed keywords

INSULIN RECEPTOR SUBSTRATE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P110; PROTEIN P85; PROTEIN P85ALPHA; PROTEIN SUBUNIT; S6 KINASE; THREONINE; TYROSINE; UNCLASSIFIED DRUG; GLUCOSE;

ADULT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SUBUNIT; FEMALE; GENE EXPRESSION REGULATION; GLUCOSE CLAMP TECHNIQUE; HUMAN; HUMAN TISSUE; INSULIN RESISTANCE; INSULIN SENSITIVITY; MOLECULAR BIOLOGY; MUSCLE BIOPSY; NORMAL HUMAN; NUTRITION; OVERNUTRITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; METABOLISM; PHOSPHORYLATION; TIME; UPREGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADULT; FEMALE; GLUCOSE; HUMANS; INSULIN RESISTANCE; NUTRITION PHYSIOLOGY; PHOSPHORYLATION; PROTEIN SUBUNITS; TIME FACTORS; UP-REGULATION;

EID: 33644832891     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-006-0148-0     Document Type: Article

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