T-588 enhances neurite outgrowth and choline acetyltransferase in cultured rat spinal ventral horn neurons

Neurochemical Research

Volumn 27, Issue 3, 2002, Pages 225-228

  Iwasaki, Y ^a   Ikeda, K ^a   Ichikawa, Y ^a   Igarashi, O ^a   Kinoshita, M ^a   Marubuchi, S ^b   Ono, S ^b  

^a TOHO UNIVERSITY   (Japan)

^b Research Laboratories   (Japan)

Author keywords

Motor neuron disease; Neurite outgrowth; T 588; Trophic effect; Ventral spinal cord culture

Indexed keywords

1 (BENZO[B]THIEN 5 YL) 2 (2 DIETHYLAMINOETHOXY)ETHANOL; CHOLINE ACETYLTRANSFERASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; EMBRYO; FETUS; MOTOR NEURON DISEASE; MOTOR NEUROPATHY; NERVE CELL; NERVE CELL NECROSIS; NERVE DEGENERATION; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD VENTRAL HORN;

ANIMALS; ANTERIOR HORN CELLS; CELLS, CULTURED; CHOLINE O-ACETYLTRANSFERASE; DIETHYLAMINES; EMBRYO; NEURITES; ORGAN CULTURE TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD; THIOPHENES; TIME FACTORS;

ANIMALIA;

EID: 0036208503     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1014884504879     Document Type: Article

References (12)

1. Protective effect of R(-)-1-(benzo[b]thiophen-5-yl)-2-[2-(N,N-diethylamino)ethoxy] ethanol hydrochloride(T-588), a novel cerebral activator, against experimental cerebral anoxia
2. A new cognition-enhancing agent, (R)-(-)-1-(benzo[b]thiophen-5-yl)-2-[2-(N,N-diethylamino)ethoxy]ethanol hydrochloride. Effects on memory impairment in rats generated by cerebral embolization and basal forebrain lesions
3. Reduced facilitation and vesicular uptake in crustacean and mammalian neuromuscular junction by T-588, a neuroprotective compound
4. T-588 inhibits astrocyte apoptosis via mitogen-activated protein kinase signal pathway
5. T-588, a novel neuroprotective agent, delays progression of neuromuscular dysfunction in wobbler mouse moto-neuron disease
6. Trophic effect of various neuropeptides on the cultured ventral spinal cord of rat embryo
7. TRH analogue, TA-0910(3-methyl-(s)-5,6-dihydroorotyl-L-prolinamide) enhances neurite outgrowth in rat embryo ventral spinal cord in vitro
8. Depolarization and cAMP elevation rapidly recruit trkB to the plasma membrane of CNS neurons
9. Neurotrophic factors and neuromuscular disease: I. General comments, the neurotrophin family, and neuropoietic cytokines
10. A mechanism for the guide and topographic patterning of retinal ganglion cell axons
11. Deprenyl enhances neurite outgrowth in cultured rat spinal ventral horn neurons
12. Thyrotropin-releasing hormone enhances choline acetyltransferase and creatine kinase in cultured spinal ventral horn neurons