T-588, a novel neuroprotective agent, delays progression of neuromuscular dysfunction in wobbler mouse motoneuron disease

Brain Research

Volumn 858, Issue 1, 2000, Pages 84-91

  Ikeda, Ken ^a   Iwasaki, Yasuo ^a   Kinoshita, Masao ^a   Marubuchi, Shigeki ^b   Ono, Satoshi ^b  

^a TOHO UNIVERSITY OHASHI MEDICAL CENTER   (Japan)

^b Research Laboratories   (Japan)

Author keywords

cAMP; ChAT; LDH; Motoneuron disease; T 588; Wobbler mouse

Indexed keywords

1 (BENZO[B]THIEN 5 YL) 2 (2 DIETHYLAMINOETHOXY)ETHANOL; CHOLINE ACETYLTRANSFERASE; CYCLIC AMP; LACTATE DEHYDROGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BICEPS BRACHII MUSCLE; CERVICAL SPINAL CORD; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; ENZYME ACTIVITY; GRIP STRENGTH; MOTOR NEURON DISEASE; MOUSE; MUSCLE ATROPHY; NEUROMUSCULAR FUNCTION; NONHUMAN; PRIORITY JOURNAL;

ADMINISTRATION, ORAL; ANIMALS; CELL COUNT; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM STIMULANTS; CHOLINE O-ACETYLTRANSFERASE; CYCLIC AMP; DIETHYLAMINES; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DRUG EVALUATION, PRECLINICAL; FORELIMB; HAND STRENGTH; L-LACTATE DEHYDROGENASE; MICE; MICE, INBRED C57BL; MICE, NEUROLOGIC MUTANTS; MOTOR NEURON DISEASE; MUSCLE, SKELETAL; ORGAN SIZE; SPINAL CORD; THIOPHENES;

EID: 0033965941     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)02427-0     Document Type: Article

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