Electrostatic orientation of enzymes on surfaces for ligand screening probed by force spectroscopy

Langmuir

Volumn 22, Issue 3, 2006, Pages 887-892

  Wang, Xiuzhu ^a   Zhou, Dejian ^a   Sinniah, Kumar ^a   Clarke, Caroline ^a   Birch, Louise ^a   Li, Haitao ^a   Rayment, Trevor ^a   Abell, Chris ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTROSTATIC ORIENTATION; ENZYME ORIENTATIONS; FORCE SPECTROSCOPY; SURFACE PATTERNS;

ATOMIC FORCE MICROSCOPY; ELECTROSTATICS; ENZYME IMMOBILIZATION; ENZYME INHIBITION; SCREENING; SURFACE REACTIONS;

ENZYMES;

CARBONATE DEHYDRATASE II; LIGAND;

ANIMAL; ARTICLE; ATOMIC FORCE MICROSCOPY; BINDING SITE; CATTLE; CHEMISTRY; ELECTRICITY; METHODOLOGY; STATIC ELECTRICITY; SURFACE PROPERTY;

ANIMALS; BINDING SITES; CARBONIC ANHYDRASE II; CATTLE; ELECTROSTATICS; LIGANDS; MICROSCOPY, ATOMIC FORCE; STATIC ELECTRICITY; SURFACE PROPERTIES;

EID: 33244479214     PISSN: 07437463     EISSN: None     Source Type: Journal    
DOI: 10.1021/la0525731     Document Type: Article

References (59)

1. (a) Evans, E. Annu. Rev. Biophys. Biomol. Struct. 2001, 30, 105.
2. (b) Janshoff, A.; Neitzert, M.; Oberdörfer, Y.; Fuchs, H. Angew. Chem., Int. Ed. 2000, 39, 3212.
3. (a) Grandbois, M.; Beyer, M.; Rief, M.; Clausen-Schaumann, H.; Gaub, H. E. Science 1999, 283, 1727.
4. (b) Garnier, L.; Gauthier-Manuel, B.; van der Vegte, E. W.; Snijders, J.; Hadziioannou, G. J. Chem. Phys. 2000, 113, 2497.
5. (a) Kado, S.; Kimura, K. J. Am. Chem. Soc. 2003, 125, 4560.
6. (b) Conti, M.; Falini, G.; Samorì, B. Angew. Chem. Int. Ed. 2000, 39, 215.
7. (c) Skulason, H.; Frisbie. C. D. J. Am. Chem. Soc. 2002, 124, 15125.
8. (d) Skulason, H.; Frisbie, C. D. Anal. Chem. 2002, 74, 3096.
9. (e) Schönherr, H.; Beulen, M. W. J.; Bügler, J.; Huskens, J.; van Veggel, F. C. J. M.; Reinhoudt, D. N.; Vancso, G. J. J. Am. Chem. Soc. 2000, 122, 4963.
10. Frisbie, C. D.; Rozsnyai, L. F.; Noy, A.; Wrighton, M. S.; Lieber, C. M. Science 1994, 265, 2071.
11. McKendry, R.; Theoclitou, M. E.; Rayment, T.; Abell, C. Nature 1998, 391, 566.
12. Lee, G. U.; Chrisey, L. A.; Colton, R. J. Science 1994, 266, 771.
13. (a) Florin, E. L.; Moy, V. T.; Gaub, H. E. Science 1994, 264, 415.
14. (b) Lee, G. U.; Kidwell, D. A.; Colton, R. J. Langmuir 1994, 10, 354.
15. (c) Merkel, R.; Nassoy, P.; Leung, A.; Richie, K.; Evans, E. Nature 1999, 397, 50.
16. (d) Patel, A. B.; Allen, S.; Davies, M. C.; Roberts, C. J.; Tendler, S. J. B.; Williams, P. M. J. Am. Chem. Soc. 2004, 126, 1318.
17. (e) Fiorini, M.; McKendry, R.; Cooper, M. A.; Rayment, T.; Abell, C. Biophys. J. 2001, 80, 2471.
18. (f) Schwesinger, F.; Ros, R.; Strunz, T.; Anselmetti, D.; Guntherodt, H. J.; Honegger, A.; Jermutus, L.; Tiefenauer, L.; Pluckthun, A. Proc. Natl. Acad. Sci. U.S.A. 2000, 97, 9972.
19. (g) Grubmuller, H.; Heymann, B.; Tavan, P. Science 1996, 271, 997.
20. (h) Touhami, A.; Hoffmann, B.; Vasella, A.; Denis, F. A.; Dufrêne, Y. F. Langmuir 2003, 19, 1745.
21. Meadows, P. Y.; Walker, G. C. Langmuir 2005, 21, 4096.
22. (a) Hinterdorfer, P.; Baumgartner, W.; Gruber, H. J.; Schilcher, K.; Schindler, H. Proc. Natl. Acad. Sci. U.S.A. 1996, 93, 3477.
23. (b) Willemsen, O. H.; Snel, M. M. E.; van der Werf, K. O.; de Grooth, B. G.; Greve, J.; Hinterdorfer, P.; Gruber, H. J.; Schindler, H.; van Kooyk, Y.; Figdor, C. G. Biophys. J. 1998, 75, 2220.
24. Dammer, U.; Hegner, M.; Anselmetti, D.; Wagner, P.; Dreier, M.; Huber, W.; Guntherodt, H. J. Biophys. J. 1996, 70, 2437.
25. McKendry, R.; Theoclitou, M. E.; Abell, C.; Rayment, T. Langmuir 1998, 14, 2846.
26. Sinniah, S. K.; Steel, A. B.; Miller, C. J.; ReuttRobey. J. E. J. Am. Chem. Soc. 1996, 118, 8925.
27. Prime, K. L.; Whitesides, G. M. J. Am. Chem. Soc. 1993, 115, 10714.
28. (a) Bornscheuer, U. T. Angew. Chem., Int. Ed. 2003, 42, 3336.
29. (b) Mao, H.; Yang, T.; Cremer, P. S. Anal. Chem. 2002, 74, 379.
30. (c) Delouise, L. A.; Miller, B. L. Anal. Chem. 2004, 76, 6915.
31. Hodneland, C. D.; Lee, Y. S.; Min, D. H.; Mrksich, M. Proc. Natl. Acad. Sci. U.S.A. 2002, 99, 5048.
32. (a) MacBeath, G.; Schreiber, S. L. Science 2000, 289, 1760.
33. (b) Wilson, D. S.; Nock, S. Curr. Opin. Chem. Biol. 2002, 6, 81.
34. Chen, X.; Ferrigno, R.; Yang, J.; Whitesides, G. M. Langmuir 2002, 18, 7009.
35. (a) Chen, S.; Liu, L.; Zhou, J.; Jiang, S. Langmuir 2003, 19, 2859.
36. (b) Buijs, J.; White, D. D.; Norde, W. Colloids Surf., B 1997, 8, 239.
37. (c) Hong, R.; Fisher, N. O.; Verma, A.; Goodman, C. M.; Emrick, T.; Rotello, V. M. J. Am. Chem. Soc. 2004, 126, 739.
38. Zhou, D. J.; Wang, X. Z.; Birch, L.; Rayment, T.; Abell, C. Langmuir 2003, 19, 10557.
39. (a) Scozzafava, A.; Menabuoni, L.; Mincione, F.; Briganti, F.; Mincione, G.; Supuran, C. T. J. Med. Chem. 1999, 42, 2641.
40. (b) Liljas, A.; Hakansson, K.; Jonsson, B. H.; Xue, Y. F. Eur. J. Biochem. 1994, 219, 1.
41. (c) Lahiri, J.; Isaacs, L.; Grzybowski, B.; Carbeck, J. D.; Whitesides, G. M. Langmuir 1999, 15, 7186.
42. (a) Wagner, P.; Hegner, M.; Guntherodt, H. J.; Semenza, G. Langmuir 1995, 11, 3867.
43. (b) Zhou, D. J.; Sinniah, K.; Abell, C.; Rayment, T. Langmuir 2002, 18, 8278.
44. (c) Wadu-Mesthrige, K.; Amro, N. A.; Garno, J. C.; Xu, S.; Liu, G. Y. Biophys. J. 2001, 80, 1891.
45. (a) Xia, Y. N.; Rogers, J. A.; Paul, K. E.; Whitesides, G. M. Chem. Rev. 1999, 99, 1823.
46. (b) Michel, B.; Bernard, A.; Bietsch, A.; Delamarche,E.; Geissler, M.; Juncker, D.; Kind, H.; Renault, J. P.; Rothuizen, H.; Schmid, H.; Schmidt-Winkel, P.; Stutz, R.; Wolf, W. IBM J. Res. Dev. 2001, 45, 697.
47. (c) Zhou, D. J.; Bruckbauer, A.: Abell, C.; Klenerman, D.; Kang, D.-J. Adv. Mater. 2005, 17, 1243.
48. (d) Zhou, D.: Bruckbauer, A.; Ying, L. M.; Abell, C.; Klenerman, D. Nano Lett. 2003, 3, 1517.
49. Day, Y. S. N.; Baird, C. L.; Rich, R. L.; Myszka, D. G. Protein Sci. 2002, 11, 1017.
50. 2, within which it would be possible to pack ∼25 carbonic anhydrase molecules if the enzyme is closely packed on the surface (carbonic anhydrase has a diameter of ∼4 nm). These are the theoretical maximum numbers, and in reality, the packing density of the enzyme would be smaller. However, this does suggest that it is highly probable that multiple enzyme-inhibitor interactions are being detected in our force spectroscopy experiment.
51. Wang, X. Z. Ph.D. Thesis, Univeristy of Cambridge, Cambridge, U.K., 2003.
52. Christianson, D. W.; Fierke, C. A. Acc. Chem. Res. 1996, 29, 331.
53. Hakansson, K.; Carlsson, M.; Svensson, L. A.; Liljas, A. J. Mol. Biol. 1992, 227, 1192.
54. DiTusa, C. A.; Christensen, T.; McCall, K. A.; Fierke, C. A.; Toone, E. J. Biochemistry 2001, 40, 5338.
55. (a) Gao, J.; Carbeck, J.; Lei, Q. P.; Smith, R. D.; Whitesides, G. M. Biophys. J. 1999, 76, 3253.
56. (b) Lindskog, S. Carbonic Anhydrase. In Zinc Enzymes; Spiro. T. G., Ed.; Wiley: New York, 1983: pp 78-121.
57. Zhou, D. J.; Sinniah, K.; Abell, C.; Rayment, T. Angew. Chem., Int. Ed. 2003, 42, 4934.
58. Sader, J. E.; Larson, I.; Mulvaney, P.; White, L. R. Rev. Sci. Instrum. 1995, 66, 3789.
59. Li, H. T.; Ren, X.; Ying, L. M.; Balasubramanian, S.; Klenerman, D. Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 14425.