The mast cell and gut nematodes: Damage and defence

Chemical Immunology and Allergy

Volumn 90, Issue , 2006, Pages 128-140

  Pennock, Joanne L ^a   Grencis, Richard K ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTEGRIN; INTERLEUKIN 3; INTERLEUKIN 4; INTERLEUKIN 8; MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1; TUMOR NECROSIS FACTOR ALPHA;

ADOPTIVE TRANSFER; ALLERGY; ASCARIASIS; ASCARIS LUMBRICOIDES; ASTHMA; ATOPY; AUTOIMMUNE DISEASE; BONE MARROW CULTURE; CELL DIFFERENTIATION; CELLULAR IMMUNITY; CROHN DISEASE; CYTOKINE RELEASE; EFFECTOR CELL; EGG PRODUCTION; ENTERITIS; ENTEROPATHY; GENETIC PREDISPOSITION; HELMINTHIASIS; IMMUNOREGULATION; IMMUNOSTIMULATION; INTESTINE LYMPHATIC TISSUE; INTESTINE MOTILITY; INTESTINE VILLUS; LAMINA PROPRIA; LYMPHOCYTE HOMING; MAST CELL; MASTOCYTOSIS; MUCOSAL IMMUNITY; NEMATODIASIS; NIPPOSTRONGYLUS BRASILIENSIS; NONHUMAN; PATHOPHYSIOLOGY; PERITONEUM MAST CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; STRONGYLOIDES VENEZUELENSIS; TH1 CELL; TH2 CELL; TRANSGENIC MOUSE; TRICHINELLA SPIRALIS; TRICHINOSIS; ULCERATIVE COLITIS; UPREGULATION;

ANIMALS; CELL ADHESION; CELL MOVEMENT; HUMANS; INTESTINES; MAST CELLS; NEMATODA; NEMATODE INFECTIONS;

EID: 33144485731     PISSN: 16602242     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Review

References (58)

1. Alizadeh H, Murrell KD: The intestinal mast cell response to Trichinella spiralis infection in mast cell-deficient WWv mice. J Parasitol 1984;70:767-773.
2. Oku Y, Itayama H, Kamiya M: Expulsion of Trichinella spiralis from the intestine of W/Wv mice reconstituted with haematopoietic and lymphopoietic cells and origin of mucosal mast cells. Immunology 1984;53:337-344.
3. Abe T, Sugaya H, Ishida K, Khan WI, Tasdemir I, Yoshimura A: Intestinal protection against Strongyloides ratti and mastocytosis induced by administration of interleukin-3 in mice. Immunology 1993;80:116-121.
4. Ben-Smith A, Lammas DA, Behnke JM: The relative involvement of Th1 and Th2 associated immune responses in the expulsion of a primary infection of Helgmosomoides polygyrus in mice of differing response phenotype. J Helminthol 2003;77:133-146.
5. Betts CJ, Else KJ: Mast cells, eosinophils and antibody-mediated cellular cytotoxicity are not critical in resistance to Trichuris muris. Parasite Immunol 1999;21:45-52.
6. Issekutz TB, Palecanda A, Kadela-Stolarz U, Marshall JS: Blockade of either alpha-4 or beta-7 integrins selectively inhibits intestinal mast cell hyperplasia and worm expulsion in response to Nippostrongylus brasiliensis infection. Eur J Immunol 2001;31:860-868.
7. Newlands GFJ, Miller HRP, Mackellar A, Galli SJ: Stem cell factor contributes to intestinal mucosal mast cell hyperplasia in rats infected with Nippostrongylus brasiliensis or Trichinella spiralis, but anti-stem cell factor treatment decreases parasite egg production during N. brasiliensis infection. Blood 1995;86:1968-1976.
8. Grencis RK, Else KJ, Nishikawa SI: The in vivo role of stem cell factor (c-kit ligand) on mastocytosis and host protective immunity to the intestinal nematode Trichinella spiralis in mice. Parasite Immunol 1993;15:55-59.
9. Fukao T, Yamada T, Tanabe M, Terauchi Y, Ota T, Takayama T, Asano T, Takeuchi T, Kadowaki T, Hata J-I, Koyasu S: Selective loss of gastrointestinal mast cells and impaired immunity in PI3K-deficient mice. Nat Immunol 2002;3:295-303.
10. Nishida K, Wang L, Morii E, Park SJ, Narimatsu M, Itoh S, Yamasaki S, Jufishima M, Ishihara K, Hibi M, Kitamura Y, Hirano T: Requirement of Gab2 for mast cell development and KitL/c-Kit signaling. Blood 2002;99:1866-1869.
11. Mahida YR: Host-parasite interactions in rodent nematode infections. J Helminthol 2005;26: 125-131.
12. Finkelman FD, Wynn TA, Donaldson DD, Urban JF Jr: The role of IL-13 in helminth-induced inflammation and protective immunity against nematode infections. Curr Opin Immunol 1999;11:420-426.
13. Townsend JM, Fallon GP, Matthews JD, Smith P, Jolin EL, McKenzie NA: IL-9 deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia byt not T cell development. Immunity 2000;13:573-583.
14. Richard M, Grencis RK, Humphreys NE, Renauld J-C, Van Snick J: Anti-IL-9 vaccination prevents worm expulsion and blood eosinophilia in Trichuris muris-infected mice. Proc Natl Acad Sci USA 2000;97:767-772.
15. Helmby H, Grencis RK: Contrasting roles for IL-10 in protective immunity to different life cycle stages of intestinal nematode parasites. Eur J Immunol 2003;33:2382-2390.
16. Lorentz A, Bischoff SC: Regulation of human intestinal mast cells by stem cell factor and IL-4. Immunol Rev 2001;179:57-60.
17. Urban JP Jr, Noben-Trauth N, Schopf L, Madden KB, Finkelman FD: Cutting edge: Il-4 receptor expression by non-bone marrow-derived cells is required to expel gastrointestinal nematode parasites. J Immunol 2001;167:6078-6081.
18. Min B, Prout M, Hu-Li J, Zhu J, Jankovic D, Morgan ES, Urban JF Jr, Dvorak AM, Finkelman FD, LeGros G, Paul WE: Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite. J Exp Med 2004;200:507-517.
19. Lantz CS, Boesiger J, Song CH, Mach N, Kobayashi K, Mulligan RC, Nawa Y: Role for interleukin-3 in mast-cell and basophil development and in immunity to parasites. Nature 1998;392: 90-93.
20. Wright SH, Brown JK, Knight PA, Thornton EM, Kilshaw PJ, Miller HRP: Transforming growth factor-β1 mediates coexpression of the integrin subunit αE and the chymase mouse mast cell protease-1 during the early differentiation of bone marrow-derived mucosal mast cell homologues. Clin Exp Allergy 2002;32:315-324.
21. Brown JK, Knight PA, Pemberton AD, Wright SH, Pate JA, Thornton EM, Miller HRP: Expression of integrin-αE by mucosal mast cells in the intestinal epithelium and its absence in nematode-intected mice lacking the transforming growth factor-β1-activating integrin αVβ6. Am J Pathol 2004;165:95-106.
22. Pennock JL, Grencis RK: In vivo exit of c-kit+/CD49d(hi)/beta7+ mucosal mast cell precursors from the bone marrow following infection with the intestinal nematode Trichinella spiralis. Blood 2004;103:2655-2660.
23. Gurish MF, Tao H, Abonia JP, Arya A, Friend DS, Parker CM, Austen KF: Intestinal mast cell progenitors require CD49dβ7 (α4β7 Integrin) for tissue-specific homing. J Exp Med 2001;194: 1243-1252.
24. Artis D, Humphreys NE, Potten CS, Wagner N, Muller W, McDermott JR, Grencis RK, Else KJ: β7 integrin-deficient mice: Delayed leukocyte recruitment and attenuated protective immunity in the small intestine during enteric helminth infection. Eur J Immunol 2000;30: 1656-1664.
25. Kasugai T, Tei H, Okada M, Hirota S, Morimoto M, Yamada M, Nakama A, Arizono N, Kitamura Y: Infection with Nippostrongylus brasiliensis induces invasion of mast cell precursors from peripheral blood to small intestine. Blood 1995;85:1334-1340.
26. Knight PA, Wright SH, Lawrence CE, Paterson YYW, Miller HRP: Delayed expulsion of the nematode Trichinella spiralis in mice lacking the mucosal mast cell-specific granule chymase, mouse mast cell protease-1. J Exp Med 2000;192:1849-1856.
27. Ghildyal N, McNeil HP, Stechschulte S, Austen F, Silberstein D, Gurish MF, Somerville LL, Stevens RL: IL-10 induces transciption of the gene for mouse mCell protease-1: A serine protease preferentially expressed in mucosal mast cells of Trichinella spiralis-infected mice. J Immunol 1992;149:2123-2129.
28. Rhoads ML, Fetterer RH, Hill DE, Urban JF Jr: Trichuris suis: A secretory hymotrypsin/elastase inhibitor with potential as an immunomodulator. Exp Parasitol 2000;95:36-44.
29. Madden KB, Whitman L, Sullivan C, Gause WC, Urban JF, Katona IM, Finkelman FD, Shea-Donohue T: Role of STAT6 and mast cells in IL-4 and IL-13-induced alterations in murine intestinal epithelial cell function. J Immunol 2002;169:4417-4422.
30. McDermott JR, Bartram RE, Knight PA, Miller HRP, Garrod DR, Grencis RK: Mast cells disrupt epithelial barrier function during enteric nematode infection. Proc Natl Acad Sci USA 2003;100: 7761-7766.
31. Bradding P, Feather IH, Howarth PH, Mueller R, Roberts JA, Britten K, Bews JP, Hunt TC, Okayama Y, Heusser CH: Interleukin 4 is localized to and released by human mast cells. J Exp Med 1992;176:1381-1386.
32. Grencis RK: Th2-mediated host protective immunity to intestinal nematode infections. Philos Trans R Soc Lond [B] 1997;352:1377-1384.
33. Boyce JA: Mast cells: Beyond IgE. J Allergy Clin Immunol 2003;113:24-32.
34. Wong GW, Foster PS, Yasuda S, Qi JC, Mahalingam S, Mellor EA, Katsoulotos G, Li L, Boyce JA, Krilis SA, Stevens RL: Biochemical and functional characterization of human transmembrane tryptase (TMT)/tryptase gamma. J Biol Chem 2002;277:41906-41915.
35. Chiappara G, Gagliardo R, Siena A, Bonsignore MR, Bousquet J, Bonsignore G, Vignola AM: Airway remodelling in the pathogenesis of asthma. Curr Opin Allergy Clin Immunol 2001;1: 85-93.
36. James A: Airway remodeling in asthma. Curr Opin Pulmon Med 2005;11:1-6.
37. Lawrence CE, Paterson JC, Higgins LM, MacDonald TT, Kennedy MW, Garside P: IL-4 regulated enteropathy in an intestinal nematode infection. Eur J Immunol 1998;28:2672-2684.
38. Lawrence CE, Paterson JC, Wei XO, Liew FY, Garside P, Kennedy MW: Nitric oxide mediates intestinal pathology but not immune expulsion during Trichinella spiralis infection in mice. J Immunol 2000;164:4229-4234.
39. Scales HE, Ierna MX, Gutierrez-Ramos JC, Coyle AJ, Garside P, Lawrence CE: Effect of inducible costimulator blockade on the pathological and protective immune responses induced by the gastrointestinal helminth Trichinella spiralis. Eur J Immunol 2004;34:2854-2862.
40. Wastling JM, Knight PA, Ure J, Wright SH, Thornton EM, Scudamore CL, Mason J, Smith A, Miller HRP: Histochemical and ultrastructural modification of mucosal mast cell granules in parasitized mice lacking the beta-chymase, mouse mast cell protease-1. Am J Pathol 1998;153:491-504.
41. Urban JF Jr, Noben-Trauth N, Donaldson DD, Madden KB, Morris SC, Collins M, Finkelman FD: IL-13, IL-4Rα, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis. Immunity 1998;8:255-264.
42. Brown JK, Donaldson DS, Wright SH, Miller HRP: Mucosal mast cells and nematode infection: Strain-specific differences in mast cell precursor frequency revisited. J Helminthol 2003;77:155-161.
43. Supajatura V, Ushio H, Nakao A, Akira S, Okumura K, Ra C, Ogawa H: Differential responses of mast cell Toll-like receptors 2 and 4 in allergy and innate immunity. J Clin Invest 2002;109:1351-1359.
44. Varadaradjalou S, Feger F, Thieblemont N, Hamouda NB, Pleau JM, Dy M, Arock M: Toll-like receptor 2 (TLR2) and TLR4 differentially activate human mast cells. Eur J Immunol 2003;33:899-906.
45. Medzhitov R: Toll-like receptors and innate immunity. Nat Rev Immunol 2001;1:135-145.
46. Dabbagh K, Lewis DB: Toll-like receptors and T-helper-1/T-helper-2 responses. Curr Opin Infect Dis 2003;16:199-204.
47. Goodridge HS, Marshall FA, Else KJ, Houston KM, Egan C, Al-Riyami L, Liew FY, Harnett W, Harnett MM: Immunomodulation via novel use of TLR4 by the filarial nematode phosphoryl-choline-containing secreted product, ES-62. J Immunol 2005;174:284-293.
48. Kane CM, Cervi L, Sun J, McKee AS, Masek KS, Shapira S, Hunter CA, Pearce EJ: Helminth antigens modulate TLR-initiated dendritic cell activation. J Immunol 2004;173:7454-7461.
49. Yoshikawa H, Tasaka K: Caspase-dependent and -independent apoptosis of mast cells induced by withdrawal of IL-3 is prevented by Toll-like receptor 4-mediated lipopolysaccharide stimulation. Eur J Immunol 2003;33:2149-2159.
50. Schopf LR, Hoffmann KF, Cheever AW, Urban JF Jr, Wynn TA: IL-10 is critical for host resistance and survival during gastrointestinal helminth infection. J Immunol 2002;168:2383-2392.
51. Mansfield LS, Urban JF: The pathogenesis of necrotic proliferative colitis in swine is linked to whipworm induced suppression of mucosal immunity to resident bacteria. Vet Immunol Immunopathol 1996;50:1-17.
52. Ikeda T, Funaba M: Altered function of murine mast cells in response to lipopolysaccharide and peptidoglycan. Immunol Lett 2003;88:21-26.
53. Yazdanbakhsh M, Matricardi PM: Parasites and the hygiene hypothesis: Regulating the immune system? Clin Rev Allergy Immunol 2004;26:15-24.
54. Palmer LJ, Celedon JC, Weiss ST, Wang B, Fang Z, Xu: Ascaris lumbricoides infection is associated with increased risk of childhood asthma and atopy in rural China. Am J Respir Crit Care Med 2002;165:1489-1493.
55. Cooper PJ, Chico ME, Sandoval C, Nutman TB: Atopic phenotype is an important determinant of immunoglobulin E-mediated inflammation and expression of T helper cell type 2 cytokines to ascaris antigens in children exposed to ascariasis. J Infect Dis 2004;190:1338-1346.
56. Beil WJ, McEuen AR, Schulz M, Wefelmeyer U, Kraml G, Wals AF, Jensen-Jarolim E, Pabst R, Pammer J: Selective alterations in mast cell subsets and eosinophil infiltration in two complementary types of intestinal inflammation: Ascariasis and Crohn's disease. Pathobiology 2002-2003; 70:303-313.
57. Weinstock JY Summers R, Elliott DE: Helminths and harmony. Gut 2004;53:7-9.
58. Elliott DE, Setiawan T, Metwali A, Blum A, Urban JF Jr, Weinstock JV: Heligmosomoides polygyrus inhibits established colitis in IL-10-deficient mice. Eur J Immunol 2004;34:2690-2698.