Host-parasite interactions in rodent nematode infections

Journal of Helminthology

Volumn 77, Issue 2, 2003, Pages 125-131

  Mahida, Y R ^a  

^a QUEEN S MEDICAL CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; NEUTRALIZING ANTIBODY;

ANIMAL MODEL; CELLULAR IMMUNITY; COLON FLORA; CONFERENCE PAPER; CYTOKINE PRODUCTION; GENETIC MANIPULATION; HOST PARASITE INTERACTION; IMMUNE RESPONSE; INFECTION RESISTANCE; INTESTINE EPITHELIUM; INTESTINE MUCOSA; INTESTINE MUSCLE; MOUSE; NEMATODIASIS; NIPPOSTRONGYLUS BRASILIENSIS; NONHUMAN; PHENOTYPE; RAT; RODENT DISEASE; TRICHINELLA SPIRALIS; WORM EXPULSION;

ANIMALS; COLON; CYTOKINES; EPITHELIAL CELLS; HOST-PARASITE RELATIONS; INTESTINE, SMALL; MAST CELLS; MUSCLE CONTRACTION; MUSCLE, SMOOTH; NEMATODA; NEMATODE INFECTIONS; RATS; RODENTIA; T-LYMPHOCYTES;

ANIMALIA; NEMATODA; NIPPOSTRONGYLUS BRASILIENSIS; RODENTIA; TRICHINELLA SPIRALIS; TRICHURIS; TRICHURIS MURIS;

EID: 0038782845     PISSN: 0022149X     EISSN: None     Source Type: Journal    
DOI: 10.1079/JOH2003172     Document Type: Conference Paper

References (66)

1. Akiho, H., Blennerhassett, P., Deng, Y. & Collins, S.M. (2002) Role of IL-4, IL-13, and STAT6 in inflammationinduced hypercontractility of murine smooth muscle cells, American Journal of Physiology (Gastrointestinal and Liver Physiology) 282, G226-G232.
2. Artis, D., Potten, C.S., Else, K.J., Finkelman, F.D. & Grencis, R.K. (1999) Trichuris muris: host intestinal epithelial cell hyperproliferation during chronic infection is regulated by interferon-gamma. Experimental Parasitology 92, 144-153.
3. Artis, D., Shapira, S., Mason, N., Speirs, K.M., Goldschmidt, M., Caamano, J., Liou, H.C., Hunter, C.A. & Scott, P. (2002) Differential requirement for NF-kappa B family members in control of helminth infection and intestinal inflammation. Journal of Immunology 169, 4481-4487.
4. Bancroft, A.J., McKenzie, A.N. & Grencis, R.K. (1998) A critical role for IL-13 in resistance to intestinal nematode infection. Journal of Immunology 160, 3453-3461.
5. Bancroft, A.J., Artis, D., Donaldson, D.D., Sypek, J.P. & Grencis, R.K. (2000) Gastrointestinal nematode expulsion in IL-4 knockout mice is IL-13 dependent. European Journal of Immunology 30, 2083-2091.
6. Barner, M., Mohrs, M., Brombacher, F. & Kopf, M. (1998) Differences between IL-4R alpha-deficient and IL-4deficient mice reveal a role for IL-13 in the regulation of Th2 responses. Current Biology 8, 669-672.
7. Bellaby, T., Robinson, K. & Wakelin, D. (1996) Induction of differential T-helper-cell responses in mice infected with variants of the parasitic nematode Trichuris muris. Infection and Immunity 64, 791-795.
8. Beltinger, J., McKaig, B.C., Makh, S., Stack, W.A., Hawkey, C.J. & Mahida, Y.R. (1999) Human colonic subepithelial myofibroblasts modulate transepithelial resistance and secretory response in epithelial cells. American Journal of Physiology (Cell Physiology) 277, C271-C279.
9. Betts, C.J. & Else, K.J. (1999) Mast cells, eosinophils and antibody-mediated cellular cytotoxicity are not critical in resistance to Trichuris muris. Parasite Immunology 21, 45-52.
10. Blumberg, R.S., Saubermann, L.J. & Strober, W. (1999) Animal models of mucosal inflammation and their relation to human inflammatory bowel disease. Current Opinion in Immunology 11, 648-856.
11. Ceponis, P.J., Botelho, F., Richards, C.D. & McKay, D.M. (2000) Interleukins 4 and 13 increase intestinal epithelial permeability by a phosphatidylinositol 3kinase pathway. Lack of evidence for STAT 6 involvement. Journal of Biological Chemistry 275, 29132-29137.
12. Coffman, R.L., Seymour, B.W., Hudak, S., Jackson, J. & Rennick, D. (1989) Antibody to interleukin-5 inhibits helminth-induced eosinophilia in mice. Science 245, 308-310.
13. Collins, S.M. (1996) The immunomodulation of enteric neuromuscular function: implications for motility and inflammatory disorders. Gastroenterology 111, 1683-1699.
14. Dehlawi, M.S. & Wakelin, D.W. (2002) Parameters of intestinal inflammation in mice given graded infections of the nematode Trichinella spiralis. Journal of Helminthology 76, 113-117.
15. Elliott, D.E., Urban, J.F., Argo, C.K. & Weinstock, J.V. (2000) Does failure to acquire helminth parasites predispose to Crohn's disease? Journal of the Federation of the American Society for Environmental Biology 14, 1848-1855.
16. Else, K.J., Finkelman, F.D., Maliszewski, C.R. & Grencis, R.K. (1994) Cytokine-mediated regulation of chronic intestinal helminth infection. Journal of Experimental Medicine 179, 347-351.
17. Farmer, S.G. (1981) Propulsive activity of the rat small intestine during infection with the nematode Nippostrongylus brasiliensis. Parasite Immunology 3, 227-234.
18. Ferguson, A. & Jarrett, E.E. (1975) Hypersensitivity reactions in small intestine. I Thymus dependence of experimental "partial villous atrophy". Gut 16, 114-117.
19. Finkelman, F.D., Shea-Donohue, T., Goldhill, J., Sullivan, C.A., Morris, S.C., Madden, K.B., Gause, W.C. & Urban, J.F. Jr. (1997) Cytokine regulation of host defense against parasitic gastrointestinal nematodes: lessons from studies with rodent models. Annual Reviews of Immunology 15, 505-533.
20. Friend, D.S., Ghildyal, N., Austen, K.F., Gurish, M.F., Matsumoto, R. & Stevens, R.L. (1996) Mast cells that reside at different locations in the jejunum of mice infected with Trichinella spiralis exhibit sequential changes in their granule ultrastructure and chymase phenotype. Journal of Cell Biology 135, 279-290.
21. Garside, P., Grencis, R.K. & Mowat, A.M. (1992) T lymphocyte dependent enteropathy in murine Trichinella spiralis infection. Parasite Immunology 14, 217-225.
22. Grencis, R.K., Riedlinger, J. & Wakelin, D. (1985) L3T4positive T lymphoblasts are responsible for transfer of immunity to Trichinella spiralis in mice. Immunology 56, 213-218.
23. Herndon, F.J. & Kayes, S.G. (1992) Depletion of eosinophils by anti-IL-5 monoclonal antibody treatment of mice infected with Trichinella spiralis does not alter parasite burden or immunological resistance to reinfection. Journal of Immunology 149, 3642-3647.
24. Ishikawa, N., Horii, Y. & Nawa, Y. (1993) Immunemediated alteration of the terminal sugars of goblet cell mucins in the small intestine of Nippostrongylus brasiliensis-infected rats. Immunology 78, 303-307.
25. Ishikawa, N., Horii, Y., Oinuma, T., Suganuma, T. & Nawa, Y. (1994) Goblet cell mucins as the selective barrier for the intestinal helminths: T-cell-independent alteration of goblet cell mucins by immunologically 'damaged' Nippostrongylus brasiliensis worms and its significance on the challenge infection with homologous and heterologous parasites. Immunology 81, 480-486.
26. Ishikawa, N., Wakelin, D. & Mahida, Y.R. (1997) Role of T helper 2 cells in intestinal goblet cell hyperplasia in mice infected with Trichinella spiralis. Gastroenterology 113, 542-549.
27. Ishikawa, N., Goyal, P.K., Mahida, Y.R., Li, K.F. & Wakelin, D. (1998) Early cytokine responses during intestinal parasitic infections. Immunology 93, 257-263.
28. Kamal, M., Wakelin, D., Ouellette, A.J., Smith, A., Podolsky, D.K. & Mahida, Y.R. (2001) Mucosal T cells regulate Paneth and intermediate cells numbers in the small intestine of T. spiralis-infected mice. Clinical Experimental Immunology 126, 117-125.
29. Kamiya, M., Oku, Y., Itayama, H. & Ohbayashi, M. (1985) Prolonged expulsion of adult Trichinella spiralis and eosinophil infiltration in mast cell-deficient W/Wv mice. Journal of Helminthology 59, 233-239.
30. Khan, W.I., Blennerhassett, P.A., Deng, Y., Gauldie, J., Vallance, B.A. & Collins, S.M. (2001a) IL-12 gene transfer alters gut physiology and host immunity in nematode-infected mice. American Journal of Physiology (Gastrointestinal and Liver Physiology) 281, G102-G110.
31. Khan, W.I., Blennerhasset, P., Ma, C., Matthaei, K.I. & Collins, S.M. (2001b) Stat6 dependent goblet cell hyperplasia during intestinal nematode infection. Parasite Immunology 23, 39-42.
32. Khan, W.I., Vallance, B.A., Blennerhassett, P.A., Deng, Y., Verdu, E.F., Matthaei, K.I. & Collins, S.M. (2001c) Critical role for signal transducer and activator of transcription factor 6 in mediating intestinal muscle hypercontractility and worm expulsion in Trichinella spiralis-infected mice. Infection and Immunity 69, 838-844.
33. Khan, W.I., Blennerhasset, P.A., Varghese, A.K., Chowdhury, S.K., Omsted, P., Deng, Y. & Collins, S.M. (2002) Intestinal nematode infection ameliorates experimental colitis in mice. Infection and Immunity 70, 5931-5937.
34. Knight, P.A., Wright, S.H., Lawrence, C.E., Paterson, Y.Y. & Miller, H.R. (2000) Delayed expulsion of the nematode Trichinella spiralis in mice lacking the mucosal mast cell-specific granule chymase, mouse mast cell protease-1. Journal of Experimental Medicine 192, 1849-1856.
35. Lawrence, C.E., Paterson, J.C., Higgins, L.M., MacDonald, T.T., Kennedy, M.W. & Garside, P. (1998) IL-4-regulated enteropathy in an intestinal nematode infection. European Journal of Immunology 28, 2672-2684.
36. Lawrence, R.A., Gray, C.A., Osborne, J. & Maizels, R.M. (1996) Nippostrongylus brasiliensis: cytokine responses and nematode expulsion in normal and IL-4-deficient mice. Experimental Parasitology 84, 65-73.
37. Li, K.F., Seth, R., Gray, T., Bayston, R., Mahida, Y.R. & Wakelin, D. (1998) Production of pro-inflammatory cytokines and inflammatory mediators in human intestinal epithelial cells after invasion by Trichinella spiralis. Infection and Immunity 66, 2200-2206.
38. Madden, K.B., Whitman, L., Sullivan, C., Gause, W.C., Urban, J.F. Jr., Katona, I.M., Finkelman, F.D. & Shea-Donohue, T. (2002) Role of STAT6 and mast cells in IL-4- and IL-13-induced alterations in murine intestinal epithelial cell function. Journal of Immunology 169, 4417-4422.
39. Mahida, Y.R. (2001) Rodent models of chronic intestinal inflammation. pp. 241-263 in Mahida, Y.R. (Ed.) Immunological aspects of gastroenterology. Dordrecht, Kluwer Academic Publishers.
40. Mahida, Y.R. & Johal, S. (2001) NF-κB may determine whether epithelial cell-microbial interactions in the intestine are hostile or friendly. Clinical Experimental Immunology 123, 347-349.
41. ManWarren, T., Gagliardo, L., Geyer, J., McVay, C., Pearce-Kelling, S. & Appleton, J. (1997) Invasion of intestinal epithelia in vitro by the parasitic nematode Trichinella spiralis. Infection and Immunity 65, 4806-4812.
42. Marzio, L., Blennerhassett, P., Chiverton, S., Vermillion, D.L., Langer, J. & Collins, S.M. (1990) Altered smooth muscle function in worm-free gut regions of Trichinella-infected rats. American Journal of Physiology (Gastrointestinal and Live Physiology) 259, G306-G313.
43. McKaig, B.C., Makh, S.S., Hawkey, C.J., Podolsky, D.K. & Mahida, Y.R. (1999) Normal human colonic subepithelial myofibroblasts enhance epithelial migration (restitution) via TGFβ3. American Journal of Physiology (Gastrointestinal and Liver Physiology) 276, G1087-G1093.
44. McKenzie, G.J., Bancroft, A., Grencis, R.K. & McKenzie, A.N. (1998) A distinct role for interleukin-13 in Th2-cell-mediated immune responses. Current Biology 8, 339-342.
45. Miller, H.R.P. (1987) Gastrointestinal mucus, a medium for survival and for elimination of parasitic nematodes and protozoa. Parasitology 94 (Suppl), S77-S100.
46. Mosmann, T.R. & Coffman, R.L. (1989) Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annual Reviews of Immunology 7, 145-173.
47. Ouellette, A.J. (1997) Paneth cells and innate immunity in the crypt microenvironment. Gastroenterology 113, 1779-1784.
48. Ouellette, A.J. & Bevins, C.L. (2001) Paneth cell defensins and innate immunity of the small bowel. Inflammatory Bowel Disease 7, 43-50.
49. Podolsky, D.K., Lynch-Devaney, K., Stow, J.L., Oates, P., Murgues, B., DeBeaumont, M., Sands, B.E. & Mahida, Y.R. (1993) Identification of human intestinal trefoil factor. Goblet cell-specific expression of a peptide targeted for apical secretion. Journal of Biological Chemistry 268, 6694-6702.
50. Richard, M., Grencis, R.K., Humphreys, N.E., Renauld, J.C. & Van Snick, J. (2000) Anti-IL-9 vaccination prevents worm expulsion and blood eosinophilia in Trichuris muris-infected mice. Proceedings of the National Academy of Sciences of the USA 97, 767-772.
51. Roberts-Thomson, I.C., Grove, D.I., Stevens, D.P. & Warren, K.S. (1976) Suppression of giardiasis during the intestinal phase of trichinosis in the mouse. Gut 17, 953-958.
52. Schopf, L.R., Hoffmann, K.F., Cheever, A.W., Urban, J.F. Jr. & Wynn, T.A. (2002) IL-10 is critical for host resistance and survival during gastrointestinal helminth infection. Journal of Immunology 168, 2383-2392.
53. Thim, L. (1997) Trefoil peptides: from structure to function. Cell and Molecular Life Sciences 53, 888-903.
54. Tomita, M., Itoh, H., Ishikawa, N., Higa, A., Ide, H., Murakumo, Y., Maruyama, H., Koga, Y. & Nawa, Y. (1995) Molecular cloning of mouse intestinal trefoil factor and its expression during goblet cell changes. Journal of Biochemistry 311, 293-297.
55. Urban, J.F. Jr., Noben-Trauth, N., Donaldson, D.D., Madden, K.B., Morris, S.C., Collins, M. & Finkelman, F.D. (1998) IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis. Immunity 8, 255-264.
56. Urban, J.F. Jr., Schopf, L., Morris, S.C., Orekhova, T., Madden, K.B., Betts, C.J., Gamble, H.R., Byrd, C., Donaldson, D., Else, K. & Finkelman, F.D. (2000) Stat6 signaling promotes protective immunity against Trichinella spiralis through a mast cell- and T celldependent mechanism. Journal of Immunology 164, 2046-2052.
57. Urban, J.F. Jr., Noben-Trauth, N., Schopf, L., Madden, K.B. & Finkelman, F.D. (2001) Cutting edge: IL-4 receptor expression by non-bone marrowderived cells is required to expel gastrointestinal nematode parasites. Journal of Immunology 167, 6078-6081.
58. Vallance, B.A., Croitoru, K. & Collins, S.M. (1998) T lymphocyte-dependent and -independent intestinal smooth muscle dysfunction in the T. spiralis-infected mouse. American Journal of Physiology (Gastrointestinal and Liver Physiology) 275, G1157-G1165.
59. Vallance, B.A., Matthaei, K.I., Sanovic, S., Young, I.G. & Collins, S.M. (2000) Interleukin-5 deficient mice exhibit impaired host defence against challenge Trichinella spiralis infections. Parasite Immunology 22, 487-492.
60. Wakelin, D. (1967) Acquired immunity to Trichuris muris in the albino laboratory mouse. Parasitology 57, 515-524.
61. Wakelin, D. (1978) Immunity to intestinal parasites. Nature 273, 617-620.
62. Wakelin, D. (1993) Allergic inflammation as a hypothesis for the expulsion of worms from tissues. Parasitology Today 9, 115-116.
63. Wakelin, D. & Lloyd, M. (1976) Immunity to primary and challenge infections of Trichinella spiralis in mice: a re-examination of conventional parameters. Parasitology 72, 173-182.
64. Wakelin, D. & Wilson, M.M. (1977) Evidence for the involvement of a bone marrow-derived cell population in the immune expulsion of Trichinella spiralis. Parasitology 74, 225-234.
65. Wong, W.M., Poulsom, R. & Wright, N.A. (1999) Trefoil peptides. Gut 44, 890-895.
66. Woodbury, R.G., Miller, H.R., Huntley, J.F., Newlands, G.F., Palliser, A.C. & Wakelin, D. (1984) Mucosal mast cells are functionally active during spontaneous expulsion of intestinal nematode infections in rat. Nature 312, 450-452.