Cutting edge: IL-4 receptor expression by non-bone marrow-derived cells is required to expel gastrointestinal nematode parasites

Journal of Immunology

Volumn 167, Issue 11, 2001, Pages 6078-6081

  Urban J F , Jr ^a   Noben Trauth, N ^a   Schopf, L ^a   Madden, K B ^a   Finkelman, F D ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 4 RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CELLULAR IMMUNITY; CHIMERA; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; INTESTINE CELL; MAST CELL; MOUSE; NEMATODE; NIPPOSTRONGYLUS BRASILIENSIS; NONHUMAN; PARASITOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TRICHINELLA SPIRALIS; WORM EXPULSION;

EID: 0035576190     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.167.11.6078     Document Type: Article

References (23)

1. Intestinal nematode parasites, cytokines and effector mechanisms
2. Cytokine regulation of host defense against parasitic gastrointestinal nematodes: Lessons from studies with rodent models
3. The role of IL-13 in helminth-induced inflammation and protective immunity against nematode infections
4. IL-13, IL-4Rα, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis
5. Stat6 signaling promotes protective immunity against Trichinella spiralis through a mast cell- and T cell-dependent mechanism
6. + T cell IL-4 production is revealed in IL-4-receptor-deficient mice
7. Enrichment and characterization of murine hematopoietic stem cells that express c-kit molecule
8. Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1
9. Anti-cytokine antibodies as carrier proteins: Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes
10. Development of an assay to measure in vivo cytokine production in the mouse
11. Strategies of anti-cytokine monoclonal antibody development: Immunoassay of IL-10 and IL-5 in clinical samples
12. Monoclonal antibody to murine γ interferon inhibits lymphokine-induced antiviral and macrophage tumoricidal activities
13. Antibodies to IL-3 and IL-4 suppress helminth-induced intestinal mastocytosis
14. The in vivo role of stem cell factor (c-kit ligand) on mastocytosis and host protective immunity to the intestinal nematode Trichinella spiralis in mice
15. Induction of the expulsion of Strongyloides ratti and retention of Nippostrongylus brasiliensis in athymic nude mice by repetitive administration of recombinant interleukin-3
16. IL-4 treatment can cure established gastrointestinal nematode infections in immunocompetent and immunodeficient mice
17. c)- and Jak3-dependent signaling in the proliferation and survival of murine mast cells
18. Effects of interleukin-12 on immune responses and host protection in mice infected with intestinal nematode parasites
19. Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes; comparison with IL-4 and modulation by IFN-γ or IL-10
20. Interleukin-4 modulates cholinergic neural control of mouse small intestinal longitudinal muscle
21. The role of IL-4 in Heligmosomoides polygyrus-induced alterations in murine intestinal epithelial cell function
22. Histamine sensitization of mice by Trichinella spiralis infection
23. Cytokine enhancement of anaphylaxis