Recruitment of the tyrosine phosphatase Src homology 2 domain tyrosine phosphatase-2 to the p85 subunit of phosphatidylinositol-3 (PI-3) kinase is required for insulin-like growth factor-I-dependent PI-3 kinase activation in smooth muscle cells

Endocrinology

Volumn 147, Issue 3, 2006, Pages 1458-1465

  Kwon, Mijin ^a   Ling, Yan ^a   Maile, Laura A ^a   Badley Clark, Jane ^a   Clemmons, David R ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN RECEPTOR SUBSTRATE 1; PHENYLALANINE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P110; PROTEIN P85; PROTEIN SUBUNIT; PROTEIN TYROSINE PHOSPHATASE SHP 2; SOMATOMEDIN C; TYROSINE DERIVATIVE; TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SMOOTH MUSCLE FIBER;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; AORTA; CELL MOVEMENT; CELLS, CULTURED; ENZYME ACTIVATION; FIBROBLASTS; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INSULIN-LIKE GROWTH FACTOR I; MODELS, STATISTICAL; MUSCLE, SMOOTH; MUTATION; PHENYLALANINE; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SWINE; TYROSINE;

EID: 32644444482     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2005-1115     Document Type: Article

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