Formation of distinct signalling complexes involving phosphatidylinositol 3-kinase activity with stimulation of epidermal growth factor or insulin-like growth factor-I in human skin fibroblasts

Journal of Cellular Physiology

Volumn 178, Issue 1, 1999, Pages 69-75

  Takahashi, Yoshihiko ^a   Akanuma, Yasuo ^b   Yazaki, Yoshio ^a   Kadowaki, Takashi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b INSTITUTE FOR ADULT DISEASES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P85; SOMATOMEDIN C; UNCLASSIFIED DRUG;

ARTICLE; DNA SYNTHESIS; ENZYME REGULATION; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SKIN FIBROBLAST;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; FIBROBLASTS; GRB2 ADAPTOR PROTEIN; HUMANS; INSULIN-LIKE GROWTH FACTOR I; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PHOSPHORYLATION; PRECIPITIN TESTS; PROTEIN-TYROSINE-PHOSPHATASE; PROTEINS; SHP1 PROTEIN TYROSINE PHOSPHATASE; SIGNAL TRANSDUCTION; SKIN; SRC HOMOLOGY DOMAINS; TYROSINE;

EID: 3743149505     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4652(199901)178:1<69::AID-JCP9>3.0.CO;2-Z     Document Type: Article

References (25)

1. Bennett AM, Tang TL, Sugimoto S, Walsh CT, Neel BG. 1994. Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras. Proc Natl Acad Sci U S A 91:7335-7339.
2. Cantley LC, Auger KR, Carpenter C, Duckworth B, Grazian A, Kapeller R, Soltoff SP. 1991. Oncogenes and signal transduction. Cell 64:281-302.
3. Carlberg K, Rohrschneider LR. 1997. Characterization of a novel tyrosine phosphorylated 100-kDa protein that binds to SHP-2 and phosphatidylinositol 3′-kinase in myeloid cells. J Biol Chem 272: 15943-15950.
4. Chung J, Grammer TC, Lemon KP, Kazlauskas A, Blenis J. 1994. PDGF- and insulin-dependent pp70s6k activation mediated by phosphatidylinositol-3-OH kinase. Nature 370:71-75.
5. Coughlin SR, Escobedo JA, Williams LT. 1989. Role of phosphatidylinositol kinase in PDGF receptor signal transduction. Science 243: 1191-1194.
6. Craddock BL, Welham MJ. 1997. Interleukin-3 induces association of the protein-tyrosine-phosphatase SHP2 and phosphatidylinositol 3-kinase with a 100-kDa tyrosine-phosphorylated protein in hemopoietic cells. J Biol Chem 272:29281-29289.
7. Dufourny B, Alblas J, van Teeffelen HAAM, van Schaik FMA, van der Burg B, Steenbergh PH, Sussenbach JS. 1997. Mitogenic signaling of insulin-like growth factor I in MCF-7 human breast cancer cells requires phosphatidylinositol 3-kinase and is independent of mitogen-activated protein kinase. J Biol Chem 272:31163-31171.
8. Fujioka Y, Matozaki T, Noguchi T, Iwamatsu A, Yamao T, Takahashi N, Tsuda M, Takada T, Kasuga M. 1996. A novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesion. Mol Cell Biol 16:6887-6899.
9. Gu H, Griffin JD, Neel BG. 1997. Characterization of two SHF-2-associated binding proteins and potential substrates in hematopoietic cells. J Biol Chem 272:16421-16430.
10. Herbst R, Carroll PM, Allard JD, Schilling J, Raabe T, Simon MA. 1996. Daughter of sevenless is a substrate of the phosphotyrosine phosphatase corkscrew and functions during sevenless signalling. Cell 85:899-910.
11. Holgado-Madruga M, Emlet DR, Moscatello DK, Godwin AK, Wong AJ. 1996. A Grb2-associated docking protein in EGF- and insulin-receptor signalling. Nature 379:560-564.
12. Kim H-H, Sierke SL, Koland JG. 1994. Epidermal growth factor-dependent association of phosphatidylinositol 3-kinase with the erbB3 gene product. J Biol Chem 269:24747-24755.
13. Kuhné MR, Pawson T, Lienhard GE, Feng G-S. 1993. The insulin receptor substrate-1 associates with the SH2-containing phosphotyrosine phosphatase Syp J Biol Chem 268:11479-11481.
14. Meisner H, Czech MP. 1995. Coupling of the proto-oncogene product c-Cbl to the epidermal growth factor receptor. J Biol Chem 270: 25332-25335.
15. Moscatello DK, Holgado-Madruǵa M, Elmet DR, Montgomery RB, Wong AJ. 1998. Constitutive activation of phosphatidylinositol 3-kinase by a naturally occurring mutant epidermal growth factor receptor. J Biol Chem 273:200-206.
16. Pawson T. 1995. Protein modules and signalling network. Nature 373:573-580.
17. Raabe T, Riesgo-Escovar J, Liu X, Bausenwein BS, Deak P, Maroy P, Hafen E. 1996. DOS, a novel plecstrin homology domain-containing protein required for signal transduction between sevenless and ras1 in Drosophila. Cell 85:911-920.
18. Soltoff SP, Cantley LC. 1996. p120cbl is a cytosolic adapter protein that associates with phosphoinositide 3-kinase in response to epidermal growth factor in PC12 and other cells. J Biol Chem 271:563-567.
19. Soltoff SP, Carraway KL III, Prigent SA, Gullick WG, Cantley LC. 1994. ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor. Mol Cell Biol 14:3550-3558.
20. Takahashi Y, Tobe K, Kadowaki H, Katsumata D, Fukushima Y, Yazaki Y, Akanuma Y, Kadowaki T. 1997. Roles of insulin receptor substrate-1 and Shc on insulin-like growth factor signaling in early passages of cultured human fibroblasts. Endocrinology 138:741-750.
21. Ueno H, Honda H, Nakamoto T, Yamagata T, Sakaki K, Miyagawa K, Mitani K, Yazaki Y, Hirai H. 1997. The phosphatidylinositol 3′ kinase pathway is required for the survival signal of leukocyte tyrosine kinase. Oncogene, 14:3067-3072.
22. Weidner KM, Ceare SD, Sachs M, Brinkmann V, Behrens J, Birchmeier W. 1996. Interaction between Gabi and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis. Nature 384:173-176.
23. White MF. 1994. The insulin signaling system. J Biol Chem 269: 1-4.
24. Yamamoto-Honda R, Tobe K, Kaburagi Y, Ueki K, Asai S, Yachi M, Shirouzu M, Yodoi J, Akanuma Y, Yokoyama S, Yazaki Y, Kadowaki T. 1995. Upstream mechanisms of glycogen synthase activation by insulin and insulin-like growth factor-I. Glycogen synthase activation is antagonized by wortmannin and LY294002 but not by rapamycin or by inhibiting p21ras. J Biol Chem 270:2729-2734.
25. Yamauchi K, Pessin JE. 1995. Epidermal growth factor-induced association of the SHPTP2 protein tyrosine phosphatase with a 115-kDa phosphotyrosine protein. J Biol Chem 270:14871-14874.