Progress toward re-engineering non-ribosomal peptide synthetase proteins: A potential new source of pharmacological agents

Drug Development Research

Volumn 66, Issue 1, 2005, Pages 9-18

  Stevens, Brian W ^a   Joska, Tammy M ^a   Anderson, Amy C ^b,c  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b Dartmouth College   (United States)

^c UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

Antibiotics; Non ribosomal peptide synthetase; Protein design

Indexed keywords

AMFOMYCIN; ANTIBIOTIC AGENT; BACITRACIN; BLEOMYCIN; CYCLOSPORIN; DAPTOMYCIN; EPOTHILONE DERIVATIVE; FLUOROBALHIMYCIN; FRIULIMICIN; GRAMICIDIN; ISOPENICILLIN N; MULTIENZYME COMPLEX; PEPTIDE SYNTHASE; UNCLASSIFIED DRUG; VANCOMYCIN;

DRUG SYNTHESIS; ENZYME SPECIFICITY; HYBRID; MUTATION; PHYLOGENY; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN ENGINEERING; REVIEW; SITE DIRECTED MUTAGENESIS;

EID: 32544447418     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.20041     Document Type: Review

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