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Volumn 44, Issue 2, 2006, Pages 71-79

Effect of erythromycin on the absorption of fexofenadine in the jejunum, ileum and colon determined using local intubation in healthy volunteers

Author keywords

ABCB1; Erythromycin; Fexofenadine; OATP; Regional absorption

Indexed keywords

ABBOTICIN; ERYTHROMYCIN LACTOBIONATE; FEXOFENADINE; METOCLOPRAMIDE;

EID: 32544442324     PISSN: 09461965     EISSN: None     Source Type: Journal    
DOI: 10.5414/CPP44071     Document Type: Article
Times cited : (29)

References (38)
  • 3
    • 85039346611 scopus 로고    scopus 로고
    • CDER. Clinical pharmacology/biopharmaceutics review: Allegra (Fexofenadine Hydrochloride) Tablets Application No.: 20-872 FDA, CDER
    • CDER. Clinical pharmacology/biopharmaceutics review: Allegra (Fexofenadine Hydrochloride) Tablets Application No.: 20-872, FDA, CDER; 2000.
    • (2000)
  • 4
    • 0017410222 scopus 로고
    • Measurements of intestinal permeability using low molecular weight polyethylene glycols (PEG 400). II. Application to normal and abnormal permeability states in man and animals
    • Chadwick VS, Phillips SF, Hofmann AF. Measurements of intestinal permeability using low molecular weight polyethylene glycols (PEG 400). II. Application to normal and abnormal permeability states in man and animals. Gastroenterology. 1977; 73: 247-251.
    • (1977) Gastroenterology , vol.73 , pp. 247-251
    • Chadwick, V.S.1    Phillips, S.F.2    Hofmann, A.F.3
  • 5
    • 0036791252 scopus 로고    scopus 로고
    • Performance characteristics of scintigraphic transit measurements for studies of experimental therapies
    • Cremonini F, Mullan BP, Camilleri M, Burton DD, Rank MR. Performance characteristics of scintigraphic transit measurements for studies of experimental therapies. Aliment Pharmacol Ther. 2002; 16: 1781-1790.
    • (2002) Aliment Pharmacol Ther , vol.16 , pp. 1781-1790
    • Cremonini, F.1    Mullan, B.P.2    Camilleri, M.3    Burton, D.D.4    Rank, M.R.5
  • 6
    • 0032793959 scopus 로고    scopus 로고
    • OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine
    • Cvetkovic M, Leake B, Fromm MF, Wilkinson GR, Kim RB. OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine. Drug Metab Dispos. 1999; 27: 866-871.
    • (1999) Drug Metab Dispos , vol.27 , pp. 866-871
    • Cvetkovic, M.1    Leake, B.2    Fromm, M.F.3    Wilkinson, G.R.4    Kim, R.B.5
  • 8
    • 0036159433 scopus 로고    scopus 로고
    • Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine
    • Dresser GK, Bailey DG, Leake BF, Schwarz UI, Dawson PA, Freeman DJ, Kim RB. Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine. Clin Pharmacol Ther. 2002; 71: 11-20.
    • (2002) Clin Pharmacol Ther , vol.71 , pp. 11-20
    • Dresser, G.K.1    Bailey, D.G.2    Leake, B.F.3    Schwarz, U.I.4    Dawson, P.A.5    Freeman, D.J.6    Kim, R.B.7
  • 9
    • 13944275994 scopus 로고    scopus 로고
    • Effect of grapefruit juice volume on the reduction of foxofenadine bioavailability: Possible role of organic anion transporting polypeptides
    • Dresser GK, Kim RB, Bailey DG. Effect of grapefruit juice volume on the reduction of foxofenadine bioavailability: possible role of organic anion transporting polypeptides. Clin Pharmacol Ther. 2005; 77: 170-177.
    • (2005) Clin Pharmacol Ther , vol.77 , pp. 170-177
    • Dresser, G.K.1    Kim, R.B.2    Bailey, D.G.3
  • 10
    • 0030839044 scopus 로고    scopus 로고
    • Regional intestinal permeability in rats of compounds with different physicochemical properties and transport mechanisms
    • Fagerholm U, Lindahl A, Lennernas H. Regional intestinal permeability in rats of compounds with different physicochemical properties and transport mechanisms. J Pharm Pharmacol. 1997; 49: 687-690.
    • (1997) J Pharm Pharmacol , vol.49 , pp. 687-690
    • Fagerholm, U.1    Lindahl, A.2    Lennernas, H.3
  • 12
    • 0032714220 scopus 로고    scopus 로고
    • Polar molecular surface as a dominating determinant for oral absorption and brain penetration of drugs
    • Kelder J, Grootenhuis PD, Bayada DM, Delbressine LP, Ploemen JP. Polar molecular surface as a dominating determinant for oral absorption and brain penetration of drugs. Pharm Res. 1999; 16: 1514-1519.
    • (1999) Pharm Res , vol.16 , pp. 1514-1519
    • Kelder, J.1    Grootenhuis, P.D.2    Bayada, D.M.3    Delbressine, L.P.4    Ploemen, J.P.5
  • 13
    • 0038637144 scopus 로고    scopus 로고
    • Involvement of human organic anion transporting polypeptide OATP-B (SLC21A9) in pH-dependent transport across intestinal apical membrane
    • Koboyashi D, Nozawa T, Imai K, Nezu J, Tsuji A, Tamai I. Involvement of human organic anion transporting polypeptide OATP-B (SLC21A9) in pH-dependent transport across intestinal apical membrane. J Pharmacol Exp Ther. 2003; 306: 703-708.
    • (2003) J Pharmacol Exp Ther , vol.306 , pp. 703-708
    • Koboyashi, D.1    Nozawa, T.2    Imai, K.3    Nezu, J.4    Tsuji, A.5    Tamai, I.6
  • 15
    • 0027998369 scopus 로고
    • Determinants of apical membrane permeabilities of barrier epithelia
    • Lande MB, Priver NA, Zeidel ML. Determinants of apical membrane permeabilities of barrier epithelia. Am J Physiol. 1994; 267: C367-C374.
    • (1994) Am J Physiol , vol.267
    • Lande, M.B.1    Priver, N.A.2    Zeidel, M.L.3
  • 17
    • 0142010611 scopus 로고    scopus 로고
    • P-glycoprotein increases from proximal to distal regions of human small intestine
    • Mouly S, Paine MF. P-glycoprotein increases from proximal to distal regions of human small intestine. Pharm Res. 2003; 20: 1595-1599.
    • (2003) Pharm Res , vol.20 , pp. 1595-1599
    • Mouly, S.1    Paine, M.F.2
  • 18
  • 19
    • 0034071561 scopus 로고    scopus 로고
    • Gastric emptying: Comparison of scintigraphic, polyethylene glycol dilution, and paracetamol tracer assessment techniques
    • Naslund E, Bogefors J, Gryback P, Jacobsson H, Hellstrom PM. Gastric emptying: comparison of scintigraphic, polyethylene glycol dilution, and paracetamol tracer assessment techniques. Scand J Gastroenterol. 2000; 35: 375-379.
    • (2000) Scand J Gastroenterol , vol.35 , pp. 375-379
    • Naslund, E.1    Bogefors, J.2    Gryback, P.3    Jacobsson, H.4    Hellstrom, P.M.5
  • 20
    • 18244386206 scopus 로고    scopus 로고
    • Fexofenadine pharmacokinetics are associated with a polymorphism of the SLCO1B1 gene (encoding OATP1B1)
    • Niemi M, Kivisto KT, Hofmann U, Schwab M, Eichelbaum M, Fromm MF. Fexofenadine pharmacokinetics are associated with a polymorphism of the SLCO1B1 gene (encoding OATP1B1). Br J Clin Pharmacol. 2005; 59: 602-604.
    • (2005) Br J Clin Pharmacol , vol.59 , pp. 602-604
    • Niemi, M.1    Kivisto, K.T.2    Hofmann, U.3    Schwab, M.4    Eichelbaum, M.5    Fromm, M.F.6
  • 21
    • 1642457252 scopus 로고    scopus 로고
    • Functional characterization of pH-sensitive organic anion transporting polypeptide OATP-B in human
    • Nozawa T, Imai K, Nezu J, Tsuji A, Tamai I. Functional characterization of pH-sensitive organic anion transporting polypeptide OATP-B in human. J Pharmacol Exp Ther. 2004; 308: 438-445.
    • (2004) J Pharmacol Exp Ther , vol.308 , pp. 438-445
    • Nozawa, T.1    Imai, K.2    Nezu, J.3    Tsuji, A.4    Tamai, I.5
  • 22
    • 0036839477 scopus 로고    scopus 로고
    • Fexofenadine transport in Caco-2 cells: Inhibition with verapamil and ritonavir
    • Perloff MD, von Moltke LL, Greenblatt DJ. Fexofenadine transport in Caco-2 cells: inhibition with verapamil and ritonavir. J Clin Pharmacol. 2002; 42: 1269-1274.
    • (2002) J Clin Pharmacol , vol.42 , pp. 1269-1274
    • Perloff, M.D.1    von Moltke, L.L.2    Greenblatt, D.J.3
  • 23
    • 4344594700 scopus 로고    scopus 로고
    • Transport characteristics of fexofenadine in the Caco-2 cell model
    • Petri N, Tannergren C, Rungstad D, Lennernas H. Transport characteristics of fexofenadine in the Caco-2 cell model. Pharm Res. 2004; 21: 1398-1404.
    • (2004) Pharm Res , vol.21 , pp. 1398-1404
    • Petri, N.1    Tannergren, C.2    Rungstad, D.3    Lennernas, H.4
  • 25
    • 0020625965 scopus 로고
    • Effect of gastrointestinal intubation on the passage of a solid meal through the stomach and small intestine in humans
    • Read NW, Al Janabi MN, Bates TE, Barber DC. Effect of gastrointestinal intubation on the passage of a solid meal through the stomach and small intestine in humans. Gastroenterology. 1983; 84: 1568-1572.
    • (1983) Gastroenterology , vol.84 , pp. 1568-1572
    • Read, N.W.1    Al Janabi, M.N.2    Bates, T.E.3    Barber, D.C.4
  • 27
    • 13944270087 scopus 로고    scopus 로고
    • Differential expression of OATP drug uptake transporters in human liver, intestine and kidney
    • Smith LH, Lee W, Kim RB. Differential expression of OATP drug uptake transporters in human liver, intestine and kidney. Drug Metab Rev. 2003; 35: 73.
    • (2003) Drug Metab Rev , vol.35 , pp. 73
    • Smith, L.H.1    Lee, W.2    Kim, R.B.3
  • 28
    • 0028847851 scopus 로고
    • Evaluation of the intestinal absorption of erythromycin in man: Absolute bioavailability and comparison with enteric coated erythromycin
    • Somogyi AA, Bochner F, Hetzel D, Williams DB. Evaluation of the intestinal absorption of erythromycin in man: absolute bioavailability and comparison with enteric coated erythromycin. Pharm Res. 1995; 12: 149-154.
    • (1995) Pharm Res , vol.12 , pp. 149-154
    • Somogyi, A.A.1    Bochner, F.2    Hetzel, D.3    Williams, D.B.4
  • 29
    • 0034709561 scopus 로고    scopus 로고
    • Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family
    • Tamai I, Nezu J, Uchino H, Sai Y, Oku A, Shimane M, Tsuji A. Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family. Biochem Biophys Res Commun. 2000; 273: 251-260.
    • (2000) Biochem Biophys Res Commun , vol.273 , pp. 251-260
    • Tamai, I.1    Nezu, J.2    Uchino, H.3    Sai, Y.4    Oku, A.5    Shimane, M.6    Tsuji, A.7
  • 30
    • 0344687432 scopus 로고    scopus 로고
    • The effect of ketoconazole on the in vivo intestinal permeability of fexofenadine using a regional perfusion technique
    • Tannergren C, Knutson T, Knutson L, Lennernas H. The effect of ketoconazole on the in vivo intestinal permeability of fexofenadine using a regional perfusion technique. Br J Clin Pharmacol. 2003a; 55: 182-190.
    • (2003) Br J Clin Pharmacol , vol.55 , pp. 182-190
    • Tannergren, C.1    Knutson, T.2    Knutson, L.3    Lennernas, H.4
  • 31
    • 0242351210 scopus 로고    scopus 로고
    • Multiple transport mechanisms involved in the intestinal absorption and first-pass extraction of fexofenadine
    • Tannergren C, Petri N, Knutson L, Hedeland M, Bondesson U, Lennernas H. Multiple transport mechanisms involved in the intestinal absorption and first-pass extraction of fexofenadine. Clin Pharmacol Ther. 2003b; 74: 423-436.
    • (2003) Clin Pharmacol Ther , vol.74 , pp. 423-436
    • Tannergren, C.1    Petri, N.2    Knutson, L.3    Hedeland, M.4    Bondesson, U.5    Lennernas, H.6
  • 32
    • 21744436852 scopus 로고    scopus 로고
    • Cytochrome P450 and MDR1 mRNA expression along the human gastrointestinal tract
    • Thorn M, Finnstrom N, Lundgren S, Rane A, Loof L. Cytochrome P450 and MDR1 mRNA expression along the human gastrointestinal tract. Br J Clin Pharmacol. 2005; 60: 54-60.
    • (2005) Br J Clin Pharmacol , vol.60 , pp. 54-60
    • Thorn, M.1    Finnstrom, N.2    Lundgren, S.3    Rane, A.4    Loof, L.5
  • 33
    • 0031946994 scopus 로고    scopus 로고
    • Membrane transport of drugs in different regions of the intestinal tract of the rat
    • Ungell AL, Nylander S, Bergstrand S, Sjoberg A, Lennernas H. Membrane transport of drugs in different regions of the intestinal tract of the rat. J Pharm Sci. 1998; 87: 360-366.
    • (1998) J Pharm Sci , vol.87 , pp. 360-366
    • Ungell, A.L.1    Nylander, S.2    Bergstrand, S.3    Sjoberg, A.4    Lennernas, H.5
  • 35
    • 2342608569 scopus 로고    scopus 로고
    • Remote controlled capsules in human drug absorption (HDA) studies
    • Wilding I, Prior D. Remote controlled capsules in human drug absorption (HDA) studies. Crit Rev Ther Drug Carrier Syst. 2003; 20: 405-431.
    • (2003) Crit Rev Ther Drug Carrier Syst , vol.20 , pp. 405-431
    • Wilding, I.1    Prior, D.2
  • 36
    • 0014185956 scopus 로고
    • Surface area of the small intestine in man
    • Wilson JP. Surface area of the small intestine in man. Gut. 1967; 8: 618-621.
    • (1967) Gut , vol.8 , pp. 618-621
    • Wilson, J.P.1
  • 37
    • 0032480901 scopus 로고    scopus 로고
    • Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach
    • Winiwarter S, Bonham NM, Ax F, Hallberg A, Lennernas H, Karlen A. Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach. J Med Chem. 1998; 41: 4939-4949.
    • (1998) J Med Chem , vol.41 , pp. 4939-4949
    • Winiwarter, S.1    Bonham, N.M.2    Ax, F.3    Hallberg, A.4    Lennernas, H.5    Karlen, A.6
  • 38
    • 11344279702 scopus 로고    scopus 로고
    • Different effects of three transporting inhibitors, verapamil, cimetidine, and probenecid, on fexofenadine pharmacokinetics
    • Yasui-Furukori N, Uno T, Sugawara K, Tateishi T. Different effects of three transporting inhibitors, verapamil, cimetidine, and probenecid, on fexofenadine pharmacokinetics. Clin Pharmacol Ther. 2005; 77: 17-23.
    • (2005) Clin Pharmacol Ther , vol.77 , pp. 17-23
    • Yasui-Furukori, N.1    Uno, T.2    Sugawara, K.3    Tateishi, T.4


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