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Volumn 142 C, Issue 1, 2006, Pages 24-32

Current perspectives on the genetic analysis of autism

Author keywords

Autism; Genetic association; Genetic linkage; Intermediate phenotype

Indexed keywords

SEROTONIN;

EID: 32444432417     PISSN: 15524868     EISSN: 15524876     Source Type: Journal    
DOI: 10.1002/ajmg.c.30079     Document Type: Review
Times cited : (20)

References (112)
  • 1
    • 0033909546 scopus 로고    scopus 로고
    • A general test of association for quantitative traits in nuclear families
    • Abecasis GR, Cardon LR, Cookson WO. 2000. A general test of association for quantitative traits in nuclear families. Am J Hum Genet 66:279-292.
    • (2000) Am J Hum Genet , vol.66 , pp. 279-292
    • Abecasis, G.R.1    Cardon, L.R.2    Cookson, W.O.3
  • 2
    • 0036338150 scopus 로고    scopus 로고
    • Merlin-rapid analysis of dense genetic maps using sparse gene flow trees
    • Abecasis G, Cherny S, Cookson W, Cardon L. 2002. Merlin-rapid analysis of dense genetic maps using sparse gene flow trees. Nat Genet 30:97-101.
    • (2002) Nat Genet , vol.30 , pp. 97-101
    • Abecasis, G.1    Cherny, S.2    Cookson, W.3    Cardon, L.4
  • 4
    • 0036138102 scopus 로고    scopus 로고
    • Evidence for a language quantitative trait locus on chromosome 7q in multiplex autism families
    • Alarcon M, Cantor RM, Liu J, Gilliam C, Autism Genetic Research Exchange Consortium, Geschwind DH. 2002. Evidence for a language quantitative trait locus on chromosome 7q in multiplex autism families. Am J Hum Genet 70:60-71.
    • (2002) Am J Hum Genet , vol.70 , pp. 60-71
    • Alarcon, M.1    Cantor, R.M.2    Liu, J.3    Gilliam, C.4    Geschwind, D.H.5
  • 5
    • 0031028361 scopus 로고    scopus 로고
    • Transmission disequilibrium tests for quantitative traits
    • Allison DB. 1997. Transmission disequilibrium tests for quantitative traits. Am J Hum Genet 60:676-690.
    • (1997) Am J Hum Genet , vol.60 , pp. 676-690
    • Allison, D.B.1
  • 6
    • 0031966959 scopus 로고    scopus 로고
    • Multipoint quantitative-trait linkage analysis in general pedigrees
    • Almasy L, Blangero J. 1998. Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet 62:1198-1211.
    • (1998) Am J Hum Genet , vol.62 , pp. 1198-1211
    • Almasy, L.1    Blangero, J.2
  • 8
    • 0036884981 scopus 로고    scopus 로고
    • Genetics of childhood disorders: XLV. Autism, part 4: Serotonin and autism
    • Anderson GM. 2002. Genetics of childhood disorders: XLV. Autism, part 4: Serotonin and autism. J Am Acad Child Adolsec Psychiatry 41:1513-1516.
    • (2002) J Am Acad Child Adolsec Psychiatry , vol.41 , pp. 1513-1516
    • Anderson, G.M.1
  • 11
    • 0029872978 scopus 로고    scopus 로고
    • Autism: Towards an integration of clinical, genetic, neuropsychological, and neurobiological perspectives
    • Bailey A, Phillips W, Rutter M. 1996. Autism: Towards an integration of clinical, genetic, neuropsychological, and neurobiological perspectives. J Child Psychol Psychiatry 37:89-126.
    • (1996) J Child Psychol Psychiatry , vol.37 , pp. 89-126
    • Bailey, A.1    Phillips, W.2    Rutter, M.3
  • 15
    • 0034757723 scopus 로고    scopus 로고
    • Prevalence of autism in a United States population: The Brick Township, New Jersey, investigation
    • Bertrand J, Mars A, Boyle C, Bove F, Yeargin-Allsopp M, Decoufle P. 2001. Prevalence of autism in a United States population: The Brick Township, New Jersey, investigation. Pediatrics 108:1155-1161.
    • (2001) Pediatrics , vol.108 , pp. 1155-1161
    • Bertrand, J.1    Mars, A.2    Boyle, C.3    Bove, F.4    Yeargin-Allsopp, M.5    Decoufle, P.6
  • 16
    • 0031949273 scopus 로고    scopus 로고
    • Genetic association mapping based on discordant sib pairs: The discordant-alleles test
    • Boehnke M, Langefeld CD. 1998. Genetic association mapping based on discordant sib pairs: The discordant-alleles test. Am J Hum Genet 62:950-961.
    • (1998) Am J Hum Genet , vol.62 , pp. 950-961
    • Boehnke, M.1    Langefeld, C.D.2
  • 20
    • 1542284674 scopus 로고    scopus 로고
    • Linkage analysis for autism in a subset families with obsessive-compulsive behaviors: Evidence for an autism susceptibility gene on chromosome 1 and further support for susceptibility genes on chromosome 6 and 19
    • Buxbaum JD, Silverman J, Keddache M, Smith CJ, Hollander E, Ramoz N, Reichert JG. 2004. Linkage analysis for autism in a subset families with obsessive-compulsive behaviors: Evidence for an autism susceptibility gene on chromosome 1 and further support for susceptibility genes on chromosome 6 and 19. Mol Psychiatry 9:144-150.
    • (2004) Mol Psychiatry , vol.9 , pp. 144-150
    • Buxbaum, J.D.1    Silverman, J.2    Keddache, M.3    Smith, C.J.4    Hollander, E.5    Ramoz, N.6    Reichert, J.G.7
  • 21
    • 0035958295 scopus 로고    scopus 로고
    • Pervasive developmental disorders in preschool children
    • Chakrabarti S, Fombonne E. 2001. Pervasive developmental disorders in preschool children. JAMA 285:3093-3099.
    • (2001) JAMA , vol.285 , pp. 3093-3099
    • Chakrabarti, S.1    Fombonne, E.2
  • 22
    • 0033237335 scopus 로고    scopus 로고
    • A generalization of the transmission/disequilibrium test for uncertain-haplotype transmission
    • Clayton D. 1999. A generalization of the transmission/disequilibrium test for uncertain-haplotype transmission. Am J Hum Genet 65:1170-1177.
    • (1999) Am J Hum Genet , vol.65 , pp. 1170-1177
    • Clayton, D.1
  • 23
    • 0034132966 scopus 로고    scopus 로고
    • Reciprocal social behavior in children with and without pervasive developmental disorders
    • Constantino JN, Przybeck T, Friesen D, Todd RD. 2000. Reciprocal social behavior in children with and without pervasive developmental disorders. J Dev Behav Pediatr 21:2-11.
    • (2000) J Dev Behav Pediatr , vol.21 , pp. 2-11
    • Constantino, J.N.1    Przybeck, T.2    Friesen, D.3    Todd, R.D.4
  • 27
    • 0028365630 scopus 로고
    • Depressive and obsessive-compulsive symptoms in hyperserotonemic parents of children with autistic disorder
    • Cook EH Jr, Charak DA, Arida J, Spohn JA, Roizen NJ, Leventhal BL. 1994. Depressive and obsessive-compulsive symptoms in hyperserotonemic parents of children with autistic disorder. Psychiatry Res 52:25-33.
    • (1994) Psychiatry Res , vol.52 , pp. 25-33
    • Cook Jr., E.H.1    Charak, D.A.2    Arida, J.3    Spohn, J.A.4    Roizen, N.J.5    Leventhal, B.L.6
  • 32
    • 0032714352 scopus 로고    scopus 로고
    • Genomic control for association studies
    • Devlin B, Roeder K. 1999. Genomic control for association studies. Biometrics 55:997-1004.
    • (1999) Biometrics , vol.55 , pp. 997-1004
    • Devlin, B.1    Roeder, K.2
  • 33
    • 0036137962 scopus 로고    scopus 로고
    • Mixture models for linkage analysis of affected sibling pairs and covariates
    • Devlin B, Jones BL, Bacanu SA, Roeder K. 2002. Mixture models for linkage analysis of affected sibling pairs and covariates. Genet Epidemiol 22:52-65.
    • (2002) Genet Epidemiol , vol.22 , pp. 52-65
    • Devlin, B.1    Jones, B.L.2    Bacanu, S.A.3    Roeder, K.4
  • 34
    • 0038449175 scopus 로고    scopus 로고
    • Analysis of multilocus models of association
    • Devlin D, Roeder K, Wasserman L. 2003. Analysis of multilocus models of association. Genet Epidemiol 25:36-47.
    • (2003) Genet Epidemiol , vol.25 , pp. 36-47
    • Devlin, D.1    Roeder, K.2    Wasserman, L.3
  • 35
    • 0025778539 scopus 로고
    • Etiology of autism: Genetic influences
    • Folstein SE, Piven J. 1991. Etiology of autism: Genetic influences. Pediatrics 87:767-773.
    • (1991) Pediatrics , vol.87 , pp. 767-773
    • Folstein, S.E.1    Piven, J.2
  • 36
    • 0017530988 scopus 로고
    • Infantile autism: A genetic study of 21 twin pairs
    • Folstein SE, Rutter M. 1977. Infantile autism: A genetic study of 21 twin pairs. J Child Psychol Psychiatry 18:297-321.
    • (1977) J Child Psychol Psychiatry , vol.18 , pp. 297-321
    • Folstein, S.E.1    Rutter, M.2
  • 38
    • 0032804766 scopus 로고    scopus 로고
    • The epidemiology of autism: A review
    • Fombonne E. 1999. the epidemiology of autism: A review. Psychol Med 29:767-786.
    • (1999) Psychol Med , vol.29 , pp. 767-786
    • Fombonne, E.1
  • 41
    • 0034098774 scopus 로고    scopus 로고
    • Allegro, a new computer program for multipoint linkage analysis
    • Gudbjartsson DF, Jonasson K, Frigge ML, Kong A. 2000. Allegro, a new computer program for multipoint linkage analysis. Nat Genet 25:12-13.
    • (2000) Nat Genet , vol.25 , pp. 12-13
    • Gudbjartsson, D.F.1    Jonasson, K.2    Frigge, M.L.3    Kong, A.4
  • 44
    • 0033940030 scopus 로고    scopus 로고
    • The transmission/disequilibrium test for linkage on the X chromosome
    • Ho GY, Bailey-Wilson JE. 2000. The transmission/disequilibrium test for linkage on the X chromosome. Am J Hum Genet 66:1158-1160.
    • (2000) Am J Hum Genet , vol.66 , pp. 1158-1160
    • Ho, G.Y.1    Bailey-Wilson, J.E.2
  • 45
    • 0032470875 scopus 로고    scopus 로고
    • A discordant-sibship test for disequilibrium and linkage: No need for parental data
    • Horvath S, Laird NM. 1998. A discordant-sibship test for disequilibrium and linkage: No need for parental data. Am J Hum Genet 63:1886-1897.
    • (1998) Am J Hum Genet , vol.63 , pp. 1886-1897
    • Horvath, S.1    Laird, N.M.2
  • 46
    • 6844251000 scopus 로고    scopus 로고
    • A full genome screen for autism with evidence for linkage to a region on chromosome 7q: International Molecular Genetic Study of Autism Consortium
    • IMGSAC
    • IMGSAC. 1998. A full genome screen for autism with evidence for linkage to a region on chromosome 7q: International Molecular Genetic Study of Autism Consortium. Hum Mol Genet 7:571-578.
    • (1998) Hum Mol Genet , vol.7 , pp. 571-578
  • 47
    • 0034883367 scopus 로고    scopus 로고
    • A genomewide screen for autism: Strong evidence for linkage to chromosomes 2q, 7q, and 16p
    • IMGSAC
    • IMGSAC. 2001. A genomewide screen for autism: Strong evidence for linkage to chromosomes 2q, 7q, and 16p. Am J Hum Genet 69:570-581.
    • (2001) Am J Hum Genet , vol.69 , pp. 570-581
  • 48
    • 0033782508 scopus 로고    scopus 로고
    • An EM algorithm for obtaining maximum likelihood estimates in the multi-phenotype variance components linkage model
    • Iturria SJ, Blangero J. 2000. An EM algorithm for obtaining maximum likelihood estimates in the multi-phenotype variance components linkage model. Ann Hum Genet 64:349-362.
    • (2000) Ann Hum Genet , vol.64 , pp. 349-362
    • Iturria, S.J.1    Blangero, J.2
  • 49
    • 0037043029 scopus 로고    scopus 로고
    • A risk-factor model of epistatic interaction, focusing on autism
    • Jones MB, Szatmari P. 2002. A risk-factor model of epistatic interaction, focusing on autism. Am J Med Genet 114:558-565.
    • (2002) Am J Med Genet , vol.114 , pp. 558-565
    • Jones, M.B.1    Szatmari, P.2
  • 52
  • 54
    • 0033814928 scopus 로고    scopus 로고
    • Implementing a unified approach to family based tests of association
    • Laird NM, Horvath S, Xu X. 2000. Implementing a unified approach to family based tests of association. Genet Epidemiol 19(suppl): 36-42.
    • (2000) Genet Epidemiol , vol.19 , Issue.SUPPL. , pp. 36-42
    • Laird, N.M.1    Horvath, S.2    Xu, X.3
  • 55
    • 0000803318 scopus 로고
    • Construction of multilocus genetic linkage maps in humans
    • Lander ES, Green P. 1987. Construction of multilocus genetic linkage maps in humans. Proc Natl Acad Sci USA 84:2363-2367.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 2363-2367
    • Lander, E.S.1    Green, P.2
  • 59
    • 2942724284 scopus 로고    scopus 로고
    • A new method for computing the multipoint posterior probability of linkage
    • Logue MW, Vieland VJ. 2004. A new method for computing the multipoint posterior probability of linkage. Hum Hered 57:90-99.
    • (2004) Hum Hered , vol.57 , pp. 90-99
    • Logue, M.W.1    Vieland, V.J.2
  • 60
    • 0035825228 scopus 로고    scopus 로고
    • Quantifying the phenotype in autism spectrum disorders
    • Lord C, Leventhal BL, Cook EH Jr. 2001. Quantifying the phenotype in autism spectrum disorders. Am J Med Genet 105:36-38.
    • (2001) Am J Med Genet , vol.105 , pp. 36-38
    • Lord, C.1    Leventhal, B.L.2    Cook Jr., E.H.3
  • 62
    • 0033910787 scopus 로고    scopus 로고
    • A test for linkage and association in general pedigrees: The pedigree disequilibrium test
    • Martin ER, Monks SA, Warren LL, Kaplan NL. 2000. A test for linkage and association in general pedigrees: The pedigree disequilibrium test. Am J Hum Genet 67:146-154.
    • (2000) Am J Hum Genet , vol.67 , pp. 146-154
    • Martin, E.R.1    Monks, S.A.2    Warren, L.L.3    Kaplan, N.L.4
  • 63
    • 24144452995 scopus 로고    scopus 로고
    • Genome-wide and Ordered-Subset linkage analyses provide support for autism loci on 17q and 19p with evidence of phenotypic and interlocus genetic correlates
    • McCauley JL, Li C, Jiang L, Olson LM, Crockett G, Gainer K, Folstein SE, Haines JL, Sutcliffe JS. 2005. Genome-wide and Ordered-Subset linkage analyses provide support for autism loci on 17q and 19p with evidence of phenotypic and interlocus genetic correlates. BMC Med Genet 6:1.
    • (2005) BMC Med Genet , vol.6 , pp. 1
    • McCauley, J.L.1    Li, C.2    Jiang, L.3    Olson, L.M.4    Crockett, G.5    Gainer, K.6    Folstein, S.E.7    Haines, J.L.8    Sutcliffe, J.S.9
  • 66
    • 0036889590 scopus 로고    scopus 로고
    • Molecular genetics of speech and language disorders
    • Newbury DF, Monaco AP. 2002. Molecular genetics of speech and language disorders. Curr Opin Pediatr 14:696-701.
    • (2002) Curr Opin Pediatr , vol.14 , pp. 696-701
    • Newbury, D.F.1    Monaco, A.P.2
  • 67
    • 9444222468 scopus 로고    scopus 로고
    • Microarray-based comparative genome hybridization and its applications in human genetics
    • Oostlander AE, Meijer GA, Ylstra B. 2004. Microarray-based comparative genome hybridization and its applications in human genetics. Clin Genet 66:488-495.
    • (2004) Clin Genet , vol.66 , pp. 488-495
    • Oostlander, A.E.1    Meijer, G.A.2    Ylstra, B.3
  • 70
    • 0029134874 scopus 로고
    • Latent-class analysis of recurrence risks for complex phenotypes with selection and measurement error: A twin and family history study of autism
    • Pickles A, Bolton P, MacDonald H, Bailey A, Le Couteur A, Sim CH, Rutter M. 1995. Latent-class analysis of recurrence risks for complex phenotypes with selection and measurement error: A twin and family history study of autism. Am J Hum Genet 57:717-726.
    • (1995) Am J Hum Genet , vol.57 , pp. 717-726
    • Pickles, A.1    Bolton, P.2    MacDonald, H.3    Bailey, A.4    Le Couteur, A.5    Sim, C.H.6    Rutter, M.7
  • 72
    • 0031035019 scopus 로고    scopus 로고
    • Broader autism phenotype: Evidence from, a family history study of multiple-incidence autism families
    • Piven J, Palmer P, Jacobi D, Childress D, Arndt S. 1997a. Broader autism phenotype: Evidence from, a family history study of multiple-incidence autism families. Am J Psychiatry 154:185-190.
    • (1997) Am J Psychiatry , vol.154 , pp. 185-190
    • Piven, J.1    Palmer, P.2    Jacobi, D.3    Childress, D.4    Arndt, S.5
  • 73
    • 0030799999 scopus 로고    scopus 로고
    • Personality and language characteristics in parents from multiple-incidence autism families
    • Piven J, Palmer P, Landa R, Santangelo S, Jacobi D, Childress D. 1997b. Personality and language characteristics in parents from multiple-incidence autism families. Am J Med Genet 74:398-411.
    • (1997) Am J Med Genet , vol.74 , pp. 398-411
    • Piven, J.1    Palmer, P.2    Landa, R.3    Santangelo, S.4    Jacobi, D.5    Childress, D.6
  • 74
    • 0029608991 scopus 로고
    • Verbal skills in relatives of autistic females
    • Plumet MH, Goldblum MC, Leboyer M. 1995. Verbal skills in relatives of autistic females. Cortex 31:723-733.
    • (1995) Cortex , vol.31 , pp. 723-733
    • Plumet, M.H.1    Goldblum, M.C.2    Leboyer, M.3
  • 75
    • 0002028461 scopus 로고    scopus 로고
    • The Role of Serotonin in Autism-Spectrum Disorders
    • Potenza MN, McDougle CJ. 1997. The Role of Serotonin in Autism-Spectrum Disorders. CNS Spectrums 2:25-42.
    • (1997) CNS Spectrums , vol.2 , pp. 25-42
    • Potenza, M.N.1    McDougle, C.J.2
  • 76
    • 0034969437 scopus 로고    scopus 로고
    • Are rare variants responsible for susceptibility to complex diseases?
    • Pritchard JK. 2001. Are rare variants responsible for susceptibility to complex diseases? Am J Hum Genet 69:124-137.
    • (2001) Am J Hum Genet , vol.69 , pp. 124-137
    • Pritchard, J.K.1
  • 77
    • 0034118493 scopus 로고    scopus 로고
    • Inference of population structure using multilocus genotype data
    • Pritchard JK, Stephens M, Donnelly PJ. 2000a. Inference of population structure using multilocus genotype data. Genetics 155:945-959.
    • (2000) Genetics , vol.155 , pp. 945-959
    • Pritchard, J.K.1    Stephens, M.2    Donnelly, P.J.3
  • 79
    • 0030827556 scopus 로고    scopus 로고
    • A transmission disequilibrium test for quantitative trait loci
    • Rabinowitz D. 1997. A transmission disequilibrium test for quantitative trait loci. Hum Hered 47:342-350.
    • (1997) Hum Hered , vol.47 , pp. 342-350
    • Rabinowitz, D.1
  • 80
    • 0003201075 scopus 로고    scopus 로고
    • A unified approach to adjusting association tests for population admixture with arbitrary pedigree structure and arbitrary missing marker information
    • Rabinowitz D, Laird NM. 2000. A unified approach to adjusting association tests for population admixture with arbitrary pedigree structure and arbitrary missing marker information. Hum Hered 504:227-233.
    • (2000) Hum Hered , vol.504 , pp. 227-233
    • Rabinowitz, D.1    Laird, N.M.2
  • 81
    • 0029743998 scopus 로고    scopus 로고
    • Practitioner review: Developmental language disorders: A clinical update
    • Rapin I. 1996. Practitioner review: Developmental language disorders: A clinical update. J Child Psychol Psychiatry 37:643-655.
    • (1996) J Child Psychol Psychiatry , vol.37 , pp. 643-655
    • Rapin, I.1
  • 83
    • 0037310257 scopus 로고    scopus 로고
    • Power of multifactor dimensionality reduction for detecting gene-gene interactions in the presence of genotyping error, missing data, phenocopy, and genetic heterogeneity
    • Ritchie MD, Hahn LW, Moore JH. 2003a. Power of multifactor dimensionality reduction for detecting gene-gene interactions in the presence of genotyping error, missing data, phenocopy, and genetic heterogeneity. Genet Epidemiol 24:150-157.
    • (2003) Genet Epidemiol , vol.24 , pp. 150-157
    • Ritchie, M.D.1    Hahn, L.W.2    Moore, J.H.3
  • 84
    • 0642368712 scopus 로고    scopus 로고
    • Optimization of neural network architecture using genetic programming improves detection and modeling of gene-gene interactions in studies of human diseases
    • Ritchie MD, White BC, Parker JS, Hahn LW, Moore JH. 2003b. Optimization of neural network architecture using genetic programming improves detection and modeling of gene-gene interactions in studies of human diseases. BMC Bioinformatics 4:28.
    • (2003) BMC Bioinformatics , vol.4 , pp. 28
    • Ritchie, M.D.1    White, B.C.2    Parker, J.S.3    Hahn, L.W.4    Moore, J.H.5
  • 85
    • 0038449167 scopus 로고    scopus 로고
    • Evolutionary-based association analysis using haplotype data
    • Seltman H, Roeder K, Devlin B. 2003. Evolutionary-based association analysis using haplotype data. Genet Epidemiol 25:48-58.
    • (2003) Genet Epidemiol , vol.25 , pp. 48-58
    • Seltman, H.1    Roeder, K.2    Devlin, B.3
  • 88
    • 0029944752 scopus 로고    scopus 로고
    • Brief report: Genetic, prenatal, and immunologic factors
    • Smalley SL, Collins F. 1996. Brief report: Genetic, prenatal, and immunologic factors. J Autism Dev Disord 26:195-198.
    • (1996) J Autism Dev Disord , vol.26 , pp. 195-198
    • Smalley, S.L.1    Collins, F.2
  • 89
    • 0031912715 scopus 로고    scopus 로고
    • A sibship test for linkage in the presence of association: The sib transmission/disequilibrium test
    • Spielman RS, Ewens WJ. 1998. A sibship test for linkage in the presence of association: The sib transmission/disequilibrium test. Am J HumGenet 62:450-458.
    • (1998) Am J HumGenet , vol.62 , pp. 450-458
    • Spielman, R.S.1    Ewens, W.J.2
  • 90
    • 0027377799 scopus 로고
    • Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)
    • Spielman RS, McGinnis RE, Ewens WJ. 1993. Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 52:506-516.
    • (1993) Am J Hum Genet , vol.52 , pp. 506-516
    • Spielman, R.S.1    McGinnis, R.E.2    Ewens, W.J.3
  • 92
    • 0029116940 scopus 로고
    • Parents and collateral relatives of children with pervasive developmental disorders: A family history study
    • Szatmari P, Jones MB, Fisman S, Tuff L, Bartolucci G, Mahoney WJ, Bryson SE. 1995. Parents and collateral relatives of children with pervasive developmental disorders: A family history study. Am J Med Gen 60:60:282-289.
    • (1995) Am J Med Gen , vol.60 , Issue.60 , pp. 282-289
    • Szatmari, P.1    Jones, M.B.2    Fisman, S.3    Tuff, L.4    Bartolucci, G.5    Mahoney, W.J.6    Bryson, S.E.7
  • 94
    • 0026494911 scopus 로고
    • A haplotype-based 'haplotype relative risk' approach to detecting allelic associations
    • Terwilliger JD, Ott J. 1992. A haplotype-based 'haplotype relative risk' approach to detecting allelic associations. Hum Hered 42:337-346.
    • (1992) Hum Hered , vol.42 , pp. 337-346
    • Terwilliger, J.D.1    Ott, J.2
  • 95
    • 21344454198 scopus 로고    scopus 로고
    • Characterizing allelic associations from unphased diploid data by graphical modeling
    • Thomas A. 2005. Characterizing allelic associations from unphased diploid data by graphical modeling. Genet Epidemiol 29:23-35.
    • (2005) Genet Epidemiol , vol.29 , pp. 23-35
    • Thomas, A.1
  • 96
    • 2442713792 scopus 로고    scopus 로고
    • Graphical modeling of the joint distribution of alleles at associated loci
    • Thomas A, Camp NJ. 2004. Graphical modeling of the joint distribution of alleles at associated loci. Am J Hum Genet 74:1088-1101.
    • (2004) Am J Hum Genet , vol.74 , pp. 1088-1101
    • Thomas, A.1    Camp, N.J.2
  • 97
    • 0042226484 scopus 로고    scopus 로고
    • Multipoint linkage analysis by blocked (Gibbs) sampling
    • Thomas A, Gutin A, Abkevich V, Bansai A. 2000. Multipoint linkage analysis by blocked (Gibbs) sampling. Stats Comp 10:259-269.
    • (2000) Stats Comp , vol.10 , pp. 259-269
    • Thomas, A.1    Gutin, A.2    Abkevich, V.3    Bansai, A.4
  • 99
    • 0032231376 scopus 로고    scopus 로고
    • Bayesian linkage analysis, or: How I learned to stop worrying and love the posterior probability of linkage
    • Vieland VJ. 1998. Bayesian linkage analysis, or: How I learned to stop worrying and love the posterior probability of linkage. Am J Hum Genet 63:947-954.
    • (1998) Am J Hum Genet , vol.63 , pp. 947-954
    • Vieland, V.J.1
  • 100
  • 101
    • 0031949066 scopus 로고    scopus 로고
    • A log-linear approach to case-parent-triad data: Assessing effects of disease genes that act either directly or through maternal effects and that may be subject to parental imprinting
    • Weinberg CR, Wilcox AJ, Lie RT. 1998. A log-linear approach to case-parent-triad data: Assessing effects of disease genes that act either directly or through maternal effects and that may be subject to parental imprinting. Am J Hum Genet 62:969-978.
    • (1998) Am J Hum Genet , vol.62 , pp. 969-978
    • Weinberg, C.R.1    Wilcox, A.J.2    Lie, R.T.3
  • 102
    • 11244294384 scopus 로고    scopus 로고
    • Joint oligogenic segregation and linkage analysis using bayesian markov chain monte carlo methods
    • Wijsman E, Yu D. 2004. Joint oligogenic segregation and linkage analysis using bayesian markov chain monte carlo methods. Mol Biotechnol 28:205-226.
    • (2004) Mol Biotechnol , vol.28 , pp. 205-226
    • Wijsman, E.1    Yu, D.2
  • 103
    • 0033747281 scopus 로고    scopus 로고
    • A phonological investigation of four siblings with childhood autism
    • Wolk L, Giesen J. 2000. A phonological investigation of four siblings with childhood autism. J Commun Disord 33:371-389.
    • (2000) J Commun Disord , vol.33 , pp. 371-389
    • Wolk, L.1    Giesen, J.2
  • 105
    • 0001200144 scopus 로고
    • Testing linkage disequilibrium between a disease gene and marker loci
    • abstr
    • Xie X, Ott J. 1993. Testing linkage disequilibrium between a disease gene and marker loci. Am J Hum Genet 53:1107 [abstr].
    • (1993) Am J Hum Genet , vol.53 , pp. 1107
    • Xie, X.1    Ott, J.2
  • 106
    • 0032465321 scopus 로고    scopus 로고
    • TDT statistics for mapping quantitative trait loci
    • Xiong MM, Krushkal J, Boerwinkle E. 1998. TDT statistics for mapping quantitative trait loci. Ann Hum Genet 62:431-452.
    • (1998) Ann Hum Genet , vol.62 , pp. 431-452
    • Xiong, M.M.1    Krushkal, J.2    Boerwinkle, E.3
  • 111
    • 0033990339 scopus 로고    scopus 로고
    • Model-free analysis and permutation test for allelic associations
    • Zhao JH, Curtis D, Sham PC. 2000. Model-free analysis and permutation test for allelic associations. Hum Hered 50:133-139.
    • (2000) Hum Hered , vol.50 , pp. 133-139
    • Zhao, J.H.1    Curtis, D.2    Sham, P.C.3
  • 112
    • 0036668723 scopus 로고    scopus 로고
    • Association mapping, using a mixture model for complex traits
    • Zhu X, Zhang S, Zhao H, Cooper RS. 2002. Association mapping, using a mixture model for complex traits. Genet Epidemiol 23:181-196.
    • (2002) Genet Epidemiol , vol.23 , pp. 181-196
    • Zhu, X.1    Zhang, S.2    Zhao, H.3    Cooper, R.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.