Altered operant responding for motor reinforcement and the determination of benchmark doses following perinatal exposure to low-level 2,3,7,8-tetrachlorodibenzo-p-dioxin

Environmental Health Perspectives

Volumn 109, Issue 6, 2001, Pages 621-627

  Markowski, V P ^a   Zareba, G ^a   Stern, S ^a   Cox, C ^a   Weiss, B ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

Benchmark dose; Estrous cycle; Operant behavior; Prenatal exposure; TCDD; Wheel running

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; CALCULATION; CONTROLLED STUDY; DATA ANALYSIS; DOSE RESPONSE; ENVIRONMENTAL EXPOSURE; ESTRUS CYCLE; EXAMINATION; FEMALE; GESTATIONAL AGE; INSTRUMENTAL CONDITIONING; MALE; MOTOR PERFORMANCE; NONHUMAN; PERINATAL PERIOD; PREGNANCY; PRIORITY JOURNAL; PROGENY; RAT; REINFORCEMENT; RUNNING; TRAINING; VAGINA CYTOLOGY;

ANIMALIA;

EID: 0035355024     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.01109621     Document Type: Article

References (55)

1. Comparisons of estimated human body burdens of dioxinlike chemicals and TCDD body burdens in experimentally exposed animals
2. AH receptor signaling pathways
3. How knockout mouse lines will be used to study the role of drug-metabolizing enzymes and their receptors during reproduction and development, and in environmental toxicity, cancer, and oxidative stress
4. Reproductive toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male rats: Different effects of in utero versus lactational exposure
5. In utero and lactational exposure of male rats to 2,3,7,8-tetrachlorodibenzo-p-dioxin. 2. Effects on sexual behavior and the regulation of luteinizing hormone secretion in adulthood
6. Exposure to TCDD during development permanently alters reproductive function in male Long-Evans rats and hamsters: Reduced ejaculated and epididymal sperm numbers and sex accessory gland weights in offspring status
7. In utero and lactational exposure of the male rat to 2,3,7,8-tetrachlorodibenzo-p-dioxin: Impaired prostate growth and development without inhibited androgen production
8. In utero 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) alters reproductive morphology and function in female rat offspring
9. In utero and lactational exposure of male rats to 2,3,7,8-tetrachlorodibenzo-p-dioxin 3. Effects on spermatogenesis and reproductive capability
10. Reproductive toxicity and tissue concentrations of low doses of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male offspring rats exposed throughout pregnancy and lactation
11. In utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces genital dysmorphogenesis in the female rat
12. In utero exposure to low doses of 2,3,7,8-tetrachlorodibenzo-p-dioxin alters reproductive development of female Long Evans hooded rat offspring
13. Effects of gestational and lactational exposure to TCDD or coplanar PCBs on spatial learning
14. Learning and memory in rats gestationally and lactationally exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
15. Radial arm maze performance in rats following gestational and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
16. Radial arm maze performance in rats following neonatal dopamine depletion
17. The relation of ovarian steroid levels in young female rats to subsequent estrous cyclicity and reproductive function during aging
18. Chronological changes in sex steroid, gonadotropin and prolactin secretion in aging female rats displaying different reproductive states
19. Circadian and estrous cycle-dependent variations in blood pressure and heart rate in female rats
20. Interactions between body temperature and wheel running over the estrous cycle in rats
21. Detailed analysis of estrous-related changes in wheel running and self-stimulation
22. Behavioral effects of dopamine agonists across the estrous cycle in rats
23. Pubertal status and sex differences: Activity and maze behavior in rats
24. Techniques for establishing schedules with wheel running as reinforcement in rats
25. Determinants of behavioral response with ozone exposure
26. Methoxychlor induces estrogen-like alterations of behavior and the reproductive tract in the female rat and hamster: Effects on sex behavior, running wheel activity, and uterine morphology
27. Progesterone-estrogen interactions in the control of activity-wheel running in the female rat
28. The effect of progesterone on the activity-wheel running of ovariectomized rats
29. Loss of reproductive competence at an earlier age in female rats exposed prenatally to ethanol
30. Prenatal and postnatal chronic lead intoxication and running wheel activity in the rat
31. Kepone, mirex, mieldrin, and aldrin: Estrogenic activity and the induction of persistent vaginal estrus and anovulation in rats following neonatal treatment
32. Reproductive function in rats exposed prenatally to pesticides and polychlorinated biphenyls (PCB)
33. Prenatal cocaine exposure produces gender-specific motor effects in aged rats
34. Dopamine functions in appetitive and defensive behaviours
35. Preferential stimulation of D1 or D2 receptors disrupts food-rewarded operant responding in rats
36. Behavioral activation in rats increases striatal dopamine metabolism measured by dialysis perfusion
37. Reproductive and perinatal toxicology
38. Chronology of neuron development: Animal studies and their clinical implications
39. Neurobehavioral toxicity of methanol reflected by operant running
40. State notation of behavioral procedures
41. Characteristics of a masculine "sex drive."
42. Learning in monkeys exposed perinatally to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
43. Acute administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in pregnant Long Evans rats: Association of measured tissue concentrations with developmental effects
44. 2,3,7,8-Tetrachlorodibenzo-p-dioxin in pregnant Long Evans rats: Disposition to maternal and embryo/fetal tissues
45. The influence of estrous cycle and intrastriatal estradiol on sensorimotor performance in the female rat
46. The effect of 6-OHDA lesions of the nucleus accumbens septum on schedule-induced drinking, wheelrunning and corticosterone levels in the rat
47. Disproportionate increases in locomotor activity in response to hormonal and photic stimuli following regional neurochemical depletions of serotonin
48. Starvation-induced hyperactivity in the rat: The role of endocrine and neurotransmitter changes
49. Developmental expression of two members of a new class of transcription factors: I. Expression of aryl hydrocarbon receptor in the C57BL/6N mouse embryo