Identification of three proteins that associate in vitro with the Leishmania (Leishmania) amazonensis G-rich telomeric strand

European Journal of Biochemistry

Volumn 271, Issue 14, 2004, Pages 3050-3063

  Fernández, Maribel F ^a   Castellari, Rafael R ^a   Conte, Fábio F ^a   Gozzo, Fábio C ^a   Sabino, Adão A ^a   Pinheiro, Hildete ^a   Novello, José C ^a   Eberlin, Marcos N ^a   Cano, Maria I N ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Affinity purification; EMSA; Leishmania amazonensis; Mass spectrometry; Telomeric proteins

Indexed keywords

DOUBLE STRANDED DNA; NUCLEOTIDE; OLIGONUCLEOTIDE; PROTEIN S 100; PROTEIN SUBUNIT; TRYPSIN;

AFFINITY CHROMATOGRAPHY; ARTICLE; COMPETITION; COMPLEX FORMATION; CROSS LINKING; DNA SEQUENCE; ELECTROSPRAY; GEL MOBILITY SHIFT ASSAY; IN VITRO STUDY; LASER; LEISHMANIA; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; NUCLEOTIDE REPEAT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PURIFICATION; RENATURATION; RNA SEQUENCE; TANDEM MASS SPECTROMETRY; TELOMERE;

ANIMALS; BASE COMPOSITION; BASE SEQUENCE; CELL FRACTIONATION; DNA, PROTOZOAN; HUMANS; LEISHMANIA; MACROMOLECULAR SUBSTANCES; MASS SPECTROMETRY; PEPTIDE MAPPING; PROTOZOAN PROTEINS; REPETITIVE SEQUENCES, NUCLEIC ACID; SALTS; TELOMERE; TELOMERE-BINDING PROTEINS;

KINETOPLASTIDA; LEISHMANIA AMAZONENSIS; PROTOZOA; TETRAHYMENA;

EID: 3242761437     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.2004.04237.x     Document Type: Article

References (52)

1. Fu, G. & Barker, D. (1998) Characterisation of Leishmania telomeres reveals unusual telomeric repeats and conserved telomere-associated sequence. Nucleic Acids Res. 26, 2161-2167.
2. Henderson, E. (1995) Telomere DNA Structure. In Telomeres (Blackburn, E. & Greider, C., eds), pp. 11-34. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
3. Henderson, E. & Blackburn, E.H. (1989) An overhanging-3′ terminus is a conserved feature of telomeres. Mol. Cell. Biol. 9, 345-348.
4. Greider, C. (1996) Telomere length regulation. Annu. Rev. Biochem. 65, 337-365.
5. Chan, S.W.-L. & Blackburn, E.H. (2002) New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin. Oncogene 21, 553-563.
6. McElligott, R. & Wellinger, R.J. (1997) The terminal DNA structure of mammalian chromosomes. EMBO J. 16, 3705-3714.
7. 1-3 tails late in s phase. Cell 72, 51-60.
8. Wellinger, R.J., Ethier, K., Labrecque, P. & Zakian, V.A. (1996) Evidence for a new step in telomere maintenance. Cell 85, 423-433.
9. de Lange, T. (2002) Protection of mammalian telomeres. Oncogene 21, 532-540.
10. Blackburn, E.H. (2000) Telomere states and cell fates. Nature 408, 53-56.
11. Blackburn, E.H. (2001) Switching and signaling at the telomere. Cell 106, 661-673.
12. 1-3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivo. Proc. Natl Acad. Sci. USA 93, 13760-13765.
13. Nugent, C., Hughes, T., Lue, N. & Lundblad, V.J. (1996) Cdc13p: a single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance. Science 274, 249-252.
14. Chandra, A., Hughes, T.R., Nugent, C.I. & Lundblad, V. (2001) Cdc13 both positively and negatively regulates telomere replication. Genes Dev. 15, 404-414.
15. Evans, S.K. & Lundblad, V.J. (1999) Est1 and Cdc13 as comediators of telomerase access. Science 286, 117-120.
16. Evans, S.K. & Lundblad, V.J. (2000) Positive and negative regulation of telomerase access to the telomere. J. Cell Sci. 19, 3357-3364.
17. Grandin, N., Reed, S.I. & Charbonneau, M. (1997) Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13. Genes Dev. 11, 512-527.
18. Grandin, N., Damon, C. & Charbonneau, M. (2001) Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13. EMBO J. 20, 1173-1183.
19. Qi, H. & Zakian, V.A. (2000) The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase α and the telomerase-associated Est1 protein. Genes Dev. 14, 1777-1788.
20. Baumann, P. & Cech, T.R. (2001) Pot1, the putative telomere end-binding protein in fission yeast and human. Science 292, 1171-1175.
21. Colgin, L.M., Baran, K., Baumann, P., Cech, T.R. & Reddel, R.R. (2003) Human POT1 facilitates telomere elongation by telomerase. Curr. Biol. 13, 942-946.
22. Loayza, D. & de Lange, T. (2003) POT1 as a terminal transducer of TRF1 telomere length control. Nature 26, 1013-1018.
23. Cano, M.I.N., Dungan, J., Agabian, N. & Blackburn, E.H. (1999) Telomerase in kinetoplastid parasitic protozoa. Proc. Natl Acad. Sci. USA 96, 3616-3621.
24. Cano, M.I.N. (2001) Telomere biology of trypanosomatids: more questions than answers. Trends Parasitol. 17, 425-429.
25. Barry, J.D., Ginger, M.L., Burton, P. & McCulloch, R. (2003) Why are parasite contingency genes often associated with telomeres? Int. J. Parasitol. 33, 29-45.
26. Eid, J. & Sollner-Webb, B. (1995) ST-1 a 39-kilodalton protein in Trypanosoma brucei, exhibist a dual affinity for the duplex form of the 29-base-pair subtelomeric repeat and its C-rich strand. Mol. Cell. Biol. 15, 389-397.
27. Eid, J. & Sollner-Webb, B. (1997) ST-2, a Telomere and subtelomere duplex and G-strand binding protein activity in Trypanosoma brucei. J. Biol. Chem. 272, 14927-14936.
28. Cano, M.I.N., Blake, J.J., Blackburn, E.H. & Agabian, N. (2002) A Trypanosoma brucei protein complex that binds G-overhangs and co-purifies with telomerase activity. J. Biol. Chem. 277, 896-906.
29. Bryan, T.M. & Cech, T.R. (1999) Telomerase and the maintenance of chromosome ends. Curr. Opin. Cell Biol. 11, 318-324.
30. Field, H. & Field, M. (1996) Leptomonas seymouri, Trypanosoma brucei: a method for isolating trypanosomatid nuclear factors which bind T. brucei single-stranded G-rich telomere sequence. Exp. Parasitol. 83, 155-158.
31. Sbicego, S., Alfonzo, J.D., Estevez, A.M., Rubio, M.A., Kang, X., Turck, C.W., Peris, M. & Simpson, L. (2003) RBP38, a novel RNA-binding protein from trypanosomatid mitochondria, modulates RNA stability. Eukaryot. Cell 2, 560-568.
32. Noll, T.M., Desponds, C., Belli, S.I., Glaser, T.A. & Fasel, N.J. (1997) Histone H1 expression varies during the Leishmania major life cycle. Mol. Biochem. Parasitol. 84, 215-227.
33. Sambrook, J. & Russel, D.W. (2001) Molecular Cloning: a Laboratory Manual, 3rd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
34. Schnapp, G., Rodi, H.-P., Rettig, W.J., Schnapp, A. & Damm, K. (1998) One-step affinity purification protocol for human telomerase. Nucleic Acids Res. 26, 3311-3313.
35. Kim, N., Piatyszek, M., Prowse, K., Harley, C., West, M., Ho, P., Coviello, G., Wright, W., Weinrich, S. & Shay, J. (1994) Specific association of human telomerase activity with immortal cell and cancer. Science 266, 2011-2015.
36. Duhagon, M.A., Dallagiovanna, B., Ciganda, M., Ruyechan, W., Williams, N. & Garat, B. (2003) A novel type of single-stranded nucleic acid binding protein recognizing a highly frequent motif in the intergenic regions of Trypanosoma cruzi. Biochem. Biophys. Res. Commun. 309, 183-188.
37. Wold, M.S. (1997) Replication Protein A: a heterotrimeric, ssDNA-binding protein required for eukaryotic DNA metabolism. Annu. Rev. Biochem. 66, 61-92.
38. Smith, J., Zou, H. & Rothstein, R. (2000) Characterization of genetic interactions with RFA1: the role of RPA in DNA replication and telomere maintenance. Biochimie 82, 71-78.
39. Chiurillo, M.A., Cano, M.I., Franco, J.S. & Ramirez, J.L. (1999) Organization of telomeric and sub-telomeric regions of chromosome from the protozoan parasite Trypanosoma cruzi. Mol. Biochem. Parasitol. 100, 173-183.
40. Price, C.M. & Cech, T.R. (1987) Telomeric DNA-protein interactions of Oxyticha macronuclear DNA. Genes Dev. 1, 783-793.
41. Virta-Pearlman, V., Morris, D.K. & Lundblad, V. (1996) Est1 has the properties of a single-stranded telomere end-binding protein. Genes Dev. 10, 3094-3104.
42. Johnston, S., Lew, J. & Berman, J. (1999) Gbp1, a protein with RNA recognition motifs, binds single-stranded telomeric DNA and changes its binding specificity upon dimerization. Mol. Cell. Biol. 19, 923-933.
43. Privalov, P.L. & Gill, S.J. (1988) Stability of protein structure and hydrophobic interaction. Adv. Protein Chem. 39, 191-234.
44. Bessler, J.B., Torredagger, J.Z. & Zakian, V.A. (2001) The Pif1p subfamily of helicases: region-specific DNA helicases? Trends Cell. Biol. 11, 60-65.
45. Bochkareva, E., Korolev, S., Less-Miller, S.P. & Bochkarev, A. (2002) Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA. EMBO J. 21, 1855-1863.
46. Murzin, A.G. (1993) OB (oligonucleotide/oligosaccharide binding)-fold: common structural and functional solution for non-homologous sequences. EMBO J. 12, 861-867.
47. Bochkareva, A., Pfuetzner, R.A., Edwards, A.M. & Frappier, L. (1997) Structure of the single-stranded-DNA-binding domain of replication protein A bound to DNA. Nature 385, 176-181.
48. Wang, W., Skopp, R., Scofield, M. & Price, C. (1992) Euplotes crassus has genes encoding telomere-binding proteins and telomere-binding protein homologs. Nucleic Acids Res. 20, 6621-6629.
49. Mitton-Fry, R.M., Anderson, E.M., Hughes, T.R., Lundblad, V. & Wuttke, D.S. (2002) Conserved structure for single-stranded telomeric DNA recognition. Science 296, 145-147.
50. Schramke, V., Luciano, P., Brevet, P., Guillot, S., Corda, Y., Longhese, M.P., Gilson, E. & Géli, V. (2004) RPA regulates telomerase action by providing Est1p access to chromosome ends. Nature Genet. 36, 46-54.
51. Opresko, P.L., von Kobbe, C., Laine, J.-P., Harrigan, J., Hickson, I.D. & Bohr, V. (2002) Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom Syndrome helicases. J. Biol. Chem. 25, 41110-41119.
52. Wong, D., Pavlovich, J.G. & Reich, N.O. (1998) Electrospray ionization mass spectrometric characterization of photocrosslinked DNA-EcoRI DNA methyltransferase complexes. Nucleic Acids Res. 26, 645-649.