γ-Aminobutyric acid enhancement of halothane binding in rat cerebellum

Neuroscience Letters

Volumn 286, Issue 2, 2000, Pages 111-114

  Eckenhoff, M F ^a   Eckenhoff, R G ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Aminobutyric acid; Agonist; Anesthetics; Autoradiography; Glutamate; Photolabeling; Receptors

Indexed keywords

4 AMINOBUTYRIC ACID; BINDING PROTEIN; CARBON 14; GLUTAMIC ACID; HALOTHANE;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CEREBELLUM; CONTROLLED STUDY; DRUG BINDING; DRUG MECHANISM; ELECTROPHYSIOLOGY; NEUROTRANSMISSION; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; RAT;

ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CARBON RADIOISOTOPES; CELL MEMBRANE; CEREBELLAR CORTEX; DRUG INTERACTIONS; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; HALOTHANE; MEMBRANE PROTEINS; NEURONS; PHOTOCHEMISTRY; RADIOLIGAND ASSAY; RATS;

EID: 0034595716     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(00)01105-8     Document Type: Article

References (19)

1. Altman J., Bayer S.A. Development of the Cerebellar System In Relation to its Evolution, Structure, and Function. 1997;26-43 CRC Press, New York.
2. Cantor R.S. The lateral pressure profile in membranes: a physical mechanism of general anesthesia. Biochemistry. 36:1997;2339-2344.
3. B binding in rat central nervous system: a quantitative autoradiographic study. Neuroscience. 34:1990;341-357.
4. Dildy-Mayfield J.E., Eger E.I., Harris R.A. Anesthetics produce subunit-selective actions on glutamate receptors. J. Pharmacol. Exp. Therap. 276:1996;1058-1065.
5. Eckenhoff M.F., Eckenhoff R.G. Quantitative autoradiography of halothane binding in rat brain. J. Pharmacol. Exp. Therap. 285:1998;371-376.
6. Eckenhoff R.G. An inhalational anesthetic binding domain in the nicotinic acetylcholine receptor. Proc. Natl. Acad. Sci. USA. 93:1996;2807-2810.
7. Eckenhoff R.G. Amino acid resolution of halothane binding sites in serum albumin. J. Biol. Chem. 271:1996;15521-15526.
8. Eckenhoff R.G., Johansson J.S. Molecular interactions between inhaled anesthetics and proteins. Pharmacol. Rev. 49:1997;343-367.
9. Eckenhoff R.G., Shuman H. Halothane binding to soluble proteins determined by photoaffinity labeling. Anesthesiology. 79:1993;96-106.
10. El-Maghrabi E.A., Eckenhoff R.G., Shuman H. Saturable binding of halothane to rat brain synaptosomes. Proc. Natl. Acad. Sci. USA. 89:1992;4329-4332.
11. Franks N.P., Lieb W.R. Molecular and cellular mechanisms of general anaesthesia. Nature. 367:1994;607-614.
12. A receptor binding in humans: quantitative imaging by positron emission tomography. Anesthesiology. 85:1996;A703.
13. Harris R.A., Mihic S.J., Dildy-Mayfield J.E., Machu T.K. Actions of anesthetics on ligand-gated ion channels: role of receptor subunit composition. FASEB J. 9:1995;1454-1462.
14. Harris B.D., Moody E.J., Basile A.S., Skolnick P. Volatile anesthetics bidirectionally and stereospecifically modulate ligand binding to GABA receptors. Eur. J. Pharmacol. 267:1994;269-274.
15. Miller K.W. Molecular mechanisms by which general anaesthetics act. Feldman S.A., Paton W., Scurr C. Mechanisms of Drugs in Anaesthesia. 1993;191-200 Hodder & Stoughton, Boston.
16. Nakahiro M., Yeh J.Z., Brunner E., Narahashi T. General anesthetics modulate GABA receptor channel complex in rat dorsal root ganglion neurons. FASEB J. 3:1989;1850-1854.
17. Raines D.E., Zachariah V.T. Isoflurane increases acetylcholine's apparent affinity for Torpedo nicotinic acetylcholine receptors. Anesthesiology. 90:1999;135-146.
18. A receptor/chloride channel complex in anesthesia. Anesthesiology. 78:1993;757-776.
19. Wakamori M., Ikemoto Y., Akaike N. Effects of two volatile anesthetics and a volatile convulsant on the excitatory and inhibitory amino acid responses in dissociated CNS neurons of the rat. J. Neurophysiol. 66:1991;2014-2021.