Biological evaluation of a technetium-99m-labeled integrated tropane-BAT and its piperidine congener as potential dopamine transporter imaging agents

Nuclear Medicine and Biology

Volumn 33, Issue 1, 2006, Pages 125-133

  Kieffer, Davy M ^a   Vanbilloen, Hubert P ^b   Cleynhens, Bernard J ^b   Terwinghe, Christelle Y ^b   Mortelmans, Luc ^b   Bormans, Guy M ^a   Verbruggen, Alfons M ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

Dopamine transporter; Piperidine; Radio LC MS; Technetium 99m BAT; Tropanes

Indexed keywords

[2 [[2 [[[3 (4 CHLOROPHENYL) 8 METHYL 8 AZABICYCLO[3.2.1]OCT 2 YL]METHYL](2 MERCAPTOETHYL)AMINO]ETHYL]AMINO]ETHANETHIOLATO]OXOTECHNETIUM TC 99M; COCAINE; DOPAMINE TRANSPORTER; HALOPERIDOL; METAL CHELATE; PIPERIDINE; TECHNETIUM 99M; TROPANE DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; AUTORADIOGRAPHY; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; ISOTOPE LABELING; NONHUMAN; RAT;

ANIMALS; BRAIN; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DRUG EVALUATION, PRECLINICAL; FEASIBILITY STUDIES; ISOTOPE LABELING; MALE; METABOLIC CLEARANCE RATE; MICE; ORGAN SPECIFICITY; ORGANOTECHNETIUM COMPOUNDS; PIPERIDINES; RADIOPHARMACEUTICALS; TISSUE DISTRIBUTION; TROPANES;

EID: 31844450438     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2005.08.006     Document Type: Article

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