Synthesis and biological evaluation of two novel DAT-binding technetium complexes containing a piperidine based analogue of cocaine

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 22, 1999, Pages 3211-3216

  Hoepping, Alexander ^a   Babich, John ^b   Zubieta, Jon A ^c   Johnson, Kenneth M ^d   Machill, Susanne ^e   Kozikowski, Alan P ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^b Biostream Inc   (United States)

^c SYRACUSE UNIVERSITY   (United States)

^d UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^e DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COCAINE; DITHIOL DERIVATIVE; DOPAMINE TRANSPORTER; DRUG ANALOG; MONOAMINE DERIVATIVE; PIPERIDINE DERIVATIVE; RHENIUM COMPLEX; TECHNETIUM COMPLEX; [2 [[2 [[[3 (4 CHLOROPHENYL) 8 METHYL 8 AZABICYCLO[3.2.1]OCT 2 YL]METHYL](2 MERCAPTOETHYL)AMINO]ETHYL]AMINO]ETHANETHIOLATO]OXOTECHNETIUM TC 99M;

ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; DRUG BINDING; DRUG BRAIN LEVEL; DRUG DESIGN; DRUG DISTRIBUTION; DRUG SYNTHESIS; DRUG UPTAKE; MALE; NONHUMAN; RAT; REACTION ANALYSIS;

ANIMALIA;

EID: 0033571663     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00562-4     Document Type: Article

References (13)

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