Rapid detection of Parkinson's disease by SPECT with altropane: A selective ligand for dopamine transporters

Synapse

Volumn 29, Issue 2, 1998, Pages 128-141

  Fischman, Alan J ^a,b   Bonab, Ali A ^a,b   Babich, John W ^a,b   Palmer, E Prather ^c   Alpert, Nathaniel M ^a,b   Elmaleh, David R ^a,b   Callahan, Ronald J ^a,b   Barrow, Sandra A ^a,b   Graham, Wendy ^a,b   Meltzer, Peter C ^d   Hanson, Robert N ^e   Madras, Bertha K ^b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c LAHEY HOSPITAL AND MEDICAL CENTER   (United States)

^d ORGANIX INC   (United States)

^e NORTHEASTERN UNIVERSITY   (United States)

Author keywords

Aging; Cocaine; Dopamine neurons; Dopamine transporter; Movement disorders; Neurodegenerative diseases; Parkinson's disease; PET imaging; SPECT imaging; WIN 35,428

Indexed keywords

2BETA CARBOMETHOXY 3BETA (4 FLUOROPHENYL) N (1 IODOPROP 1 EN 3 YL) NORTROPANE; 6 FLUORODOPA F 18; ALTROPANE; DOPAMINE TRANSPORTER; IODINE 123; TROPANE DERIVATIVE; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ARTICLE; CAUDATE NUCLEUS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; CORPUS STRIATUM; DRUG BLOOD LEVEL; DRUG METABOLISM; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MALE; OCCIPITAL CORTEX; PARKINSON DISEASE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PUTAMEN; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

ADOLESCENT; ADULT; AGED; BRAIN; BRAIN CHEMISTRY; CARRIER PROTEINS; CHILD; COCAINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; FEMALE; HUMANS; IODINE RADIOISOTOPES; LIGANDS; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MIDDLE AGED; NERVE TISSUE PROTEINS; PARKINSON DISEASE; RECEPTORS, DOPAMINE D1; TOMOGRAPHY, EMISSION-COMPUTED; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 7144227297     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2396(199806)29:2<128::AID-SYN4>3.0.CO;2-9     Document Type: Article

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