Technetium-99m SPECT imaging agent which targets the dopamine transporter in primate brain

Journal of Medicinal Chemistry

Volumn 40, Issue 12, 1997, Pages 1835-1844

  Meltzer, Peter C ^a   Blundell, Paul ^a   Jones, Alun G ^b   Mahmood, Ashfaq ^b   Garada, Basem ^b   Zimmerman, Robert E ^b   Davison, Alan ^c   Holman, B Leonard ^b   Madras, Bertha K ^d  

^a ORGANIX INC   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3BETA (4 FLUOROPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; DOPAMINE TRANSPORTER; TECHNEPINE; TECHNETIUM 99M; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN MEMBRANE; CENTRAL NERVOUS SYSTEM; CORPUS STRIATUM; DOPAMINE UPTAKE; DOPAMINERGIC NERVE CELL; DRUG RECEPTOR BINDING; LIGAND BINDING; NEUROLOGIC DISEASE; NONHUMAN; PARKINSON DISEASE; POSITRON EMISSION TOMOGRAPHY; PRIMATE; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TARGET CELL;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CARRIER PROTEINS; CORPUS STRIATUM; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; FEMALE; MACACA FASCICULARIS; MAGNETIC RESONANCE IMAGING; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MOLECULAR STRUCTURE; NERVE TISSUE PROTEINS; ORGANOTECHNETIUM COMPOUNDS; STEREOISOMERISM; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 0030947181     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960868t     Document Type: Article

References (52)

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