Synthesis and characterization of technetium-99m-labeled tropanes as dopamine transporter-imaging agents

Journal of Medicinal Chemistry

Volumn 40, Issue 1, 1997, Pages 9-17

  Meegalla, Sanath K ^a   Plössl, Karl ^a   Kung, Mei Ping ^a   Chumpradit, Sumalee ^a   Stevenson, D Andrew ^a   Kushner, Steven A ^a   McElgin, William T ^a   Mozley, P David ^a   Kung, Hank F ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

[2 [[2 [[3 (4 CHLOROPHENYL) 8 METHYL 8 AZABICYCLO[3.2.1]OCT 2 YL]METHYL](2 MERCAPTOETHYL)AMINO]ETHY]AMINO]ETHANETHIOLATO OXO TC 99M; DOPAMINE TRANSPORTER; HALOPERIDOL; TECHNETIUM 99M; TROPANE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BASAL GANGLION; CENTRAL NERVOUS SYSTEM DISEASE; CORPUS STRIATUM; DIAGNOSTIC IMAGING; DOPAMINERGIC NERVE CELL; DRUG COMPETITION; DRUG DISTRIBUTION; DRUG SYNTHESIS; PARKINSON DISEASE; POSITRON EMISSION TOMOGRAPHY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

ANIMALS; BRAIN; CARRIER PROTEINS; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; MAGNETIC RESONANCE IMAGING; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MODELS, MOLECULAR; NERVE TISSUE PROTEINS; PAPIO; RATS; RATS, SPRAGUE-DAWLEY; TECHNETIUM; TISSUE DISTRIBUTION; TROPANES;

EID: 0031033546     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960532j     Document Type: Article

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