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Volumn 25, Issue 5, 1998, Pages 531-534

Pharmacokinetics and dosimetry of iodine-123 labelled PE2I in humans, a radioligand for dopamine transporter imaging

Author keywords

Dopamine transporter; Human brain; Single photon emission tomography; Striatum

Indexed keywords

DOPAMINE TRANSPORTER; IODINE 123; PE21; RADIOLIGAND; UNCLASSIFIED DRUG;

EID: 15144360264     PISSN: 03406997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002590050254     Document Type: Article
Times cited : (49)

References (11)
  • 3
    • 0029063137 scopus 로고
    • Iodine-123 labelled N-(2-fluoroethyl)-2β-carbomethoxy-3β-(4-iodophenyl)nortropane for dopamine trans-porter imaging in the living brain
    • Kuikka JT, Åkerman K, Bergström KA, et al. Iodine-123 labelled N-(2-fluoroethyl)-2β-carbomethoxy-3β-(4-iodophenyl)nortropane for dopamine trans-porter imaging in the living brain. Eur J Nucl Med 1995; 22: 682-686.
    • (1995) Eur J Nucl Med , vol.22 , pp. 682-686
    • Kuikka, J.T.1    Åkerman, K.2    Bergström, K.A.3
  • 4
    • 14444270841 scopus 로고    scopus 로고
    • Synthesis and ligand binding of nortropane derviatives: N-substituted-2β-carbomethoxy-3β-(4-iodophenyl)nortropane and N-(3-iodoprop-2E-enyl)-2β-carbomethoxy-3β-(3′,4*- disubstituted phenyl)nortropane. New high affinity and selective compounds for the dopamine transporter
    • Edmond P, Garreau L, Chalon S, et al. Synthesis and ligand binding of nortropane derviatives: N-substituted-2β-carbomethoxy-3β-(4-iodophenyl)nortropane and N-(3-iodoprop-2E-enyl)-2β-carbomethoxy-3β-(3′,4*- disubstituted phenyl)nortropane. New high affinity and selective compounds for the dopamine transporter. J Med Chem 1997; 40: 1366-1372.
    • (1997) J Med Chem , vol.40 , pp. 1366-1372
    • Edmond, P.1    Garreau, L.2    Chalon, S.3
  • 6
    • 0031961325 scopus 로고    scopus 로고
    • Exploration of the dopamine transporter: In vitro and in vivo characterization of high affinity and high specificity iodinated tropane derivative (E)-N-(3-iodoprop-2-enyl)-2β-carbomethoxy-3β-(4′-methylphenyl) nortropane or PE2I
    • in press
    • Guilloteau D, Emond P, Baulieu JL, et al. Exploration of the dopamine transporter: in vitro and in vivo characterization of high affinity and high specificity iodinated tropane derivative (E)-N-(3-iodoprop-2-enyl)-2β-carbomethoxy-3β-(4′-methylphenyl) nortropane or PE2I. Nucl Med Biol 1998; 25: (in press).
    • (1998) Nucl Med Biol , vol.25
    • Guilloteau, D.1    Emond, P.2    Baulieu, J.L.3
  • 7
    • 0344309544 scopus 로고    scopus 로고
    • The first selective dopamine transporter radioligand suitable for quantitation with PET and SPET
    • Halldin C, Lundkvist C, Guilloteau D, et al. The first selective dopamine transporter radioligand suitable for quantitation with PET and SPET [abstract]. Eur J Nucl Med 1997; 24: 1057.
    • (1997) Eur J Nucl Med , vol.24 , pp. 1057
    • Halldin, C.1    Lundkvist, C.2    Guilloteau, D.3
  • 8
    • 12644291970 scopus 로고    scopus 로고
    • Characterization of C-11 or I-123 labelled β-CIT-FP and β-CIT-FE metabolism measured in monkey and human plasma. Identification of two labelled metabolites with HPLC
    • Bergström KA, Halldin C, Lundkvist C, et al. Characterization of C-11 or I-123 labelled β-CIT-FP and β-CIT-FE metabolism measured in monkey and human plasma. Identification of two labelled metabolites with HPLC. Hum Psychopharmacol 1996; 11: 483-490.
    • (1996) Hum Psychopharmacol , vol.11 , pp. 483-490
    • Bergström, K.A.1    Halldin, C.2    Lundkvist, C.3
  • 9
    • 0028936065 scopus 로고
    • The dopamine transporter: Immunochemical characterization and localization in brain
    • Ciliax BJ, Heilman C, Demchyshyn LL, et al. The dopamine transporter: immunochemical characterization and localization in brain. J Neurosci 1995; 15: 1714-1723.
    • (1995) J Neurosci , vol.15 , pp. 1714-1723
    • Ciliax, B.J.1    Heilman, C.2    Demchyshyn, L.L.3
  • 10
    • 0028337480 scopus 로고
    • Synthesis and characterization of radioiodinated N-(3-iodopropen-1-yl)-2β-carbomethoxy-3β-(4-chlorophenyl)tropanes: Potential dopamine reuptake site imaging agents
    • Goodman MM, Kung MP, Kabalka GW, Kung HF, Switzer R. Synthesis and characterization of radioiodinated N-(3-iodopropen-1-yl)-2β-carbomethoxy-3β-(4-chlorophenyl)tropanes: potential dopamine reuptake site imaging agents. J Med Chem 1994; 37: 1535-1542.
    • (1994) J Med Chem , vol.37 , pp. 1535-1542
    • Goodman, M.M.1    Kung, M.P.2    Kabalka, G.W.3    Kung, H.F.4    Switzer, R.5
  • 11
    • 0029957462 scopus 로고    scopus 로고
    • Imaging of dopamine transporters in humans with technetium-99m TRODAT-I
    • Kung HF, Kim HJ, Kung MP, et al. Imaging of dopamine transporters in humans with technetium-99m TRODAT-I. Eur J Nucl Med 1996; 23: 1527-1530.
    • (1996) Eur J Nucl Med , vol.23 , pp. 1527-1530
    • Kung, H.F.1    Kim, H.J.2    Kung, M.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.