메뉴 건너뛰기




Volumn 12, Issue 2, 2006, Pages 340-344

Eradication of leukemia stem cells as a new goal of therapy in leukemia

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CYTOTOXIC AGENT; PARTHENOLIDE;

EID: 31544456409     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-05-1879     Document Type: Review
Times cited : (63)

References (85)
  • 1
    • 0038011863 scopus 로고    scopus 로고
    • Stem cells: Self-renewal writ in blood
    • Dick JE. Stem cells: self-renewal writ in blood. Nature 2003;423:231-3.
    • (2003) Nature , vol.423 , pp. 231-233
    • Dick, J.E.1
  • 4
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 1997;3:730-7.
    • (1997) Nat Med , vol.3 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 5
    • 3242754448 scopus 로고    scopus 로고
    • Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity
    • Hope KJ, Jin L, Dick JE. Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity. Nat Immunol 2004;5:738-43.
    • (2004) Nat Immunol , vol.5 , pp. 738-743
    • Hope, K.J.1    Jin, L.2    Dick, J.E.3
  • 6
    • 3943088431 scopus 로고    scopus 로고
    • Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML
    • Jamieson CH, Ailles LE, Dylla SJ, et al. Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML. N Engl J Med 2004;351:657-67.
    • (2004) N Engl J Med , vol.351 , pp. 657-667
    • Jamieson, C.H.1    Ailles, L.E.2    Dylla, S.J.3
  • 7
    • 0042131826 scopus 로고    scopus 로고
    • Adult stem cells for tissue repair - A new therapeutic concept?
    • Korbling M, Estrov Z. Adult stem cells for tissue repair-a new therapeutic concept? N Engl J Med 2003;349:570-82.
    • (2003) N Engl J Med , vol.349 , pp. 570-582
    • Korbling, M.1    Estrov, Z.2
  • 8
    • 0346100567 scopus 로고    scopus 로고
    • Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors
    • Cozzio A, Passegue E, Ayton PM, Karsunky H, Cleary ML, Weissman IL. Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors. Genes Dev 2003;17:3029-35.
    • (2003) Genes Dev , vol.17 , pp. 3029-3035
    • Cozzio, A.1    Passegue, E.2    Ayton, P.M.3    Karsunky, H.4    Cleary, M.L.5    Weissman, I.L.6
  • 9
    • 0022135739 scopus 로고
    • Proposed revised criteria for the classification of acute myeloid leukemia. A report of the French-American-British Cooperative Group
    • Bennett JM, Catovsky D, Daniel MT, et al. Proposed revised criteria for the classification of acute myeloid leukemia. A report of the French-American-British Cooperative Group. Ann Intern Med 1985;103:620-5.
    • (1985) Ann Intern Med , vol.103 , pp. 620-625
    • Bennett, J.M.1    Catovsky, D.2    Daniel, M.T.3
  • 10
    • 0036786901 scopus 로고    scopus 로고
    • The World Health Organization (WHO) classification of the myeloid neoplasms
    • Vardiman JW, Harris NL, Brunning RD. The World Health Organization (WHO) classification of the myeloid neoplasms. Blood 2002;100:2292-302.
    • (2002) Blood , vol.100 , pp. 2292-2302
    • Vardiman, J.W.1    Harris, N.L.2    Brunning, R.D.3
  • 12
    • 0023202032 scopus 로고
    • Clonal development, stem-cell differentiation, and clinical remissions in acute nonlymphocytic leukemia
    • Fialkow PJ, Singer JW, Raskind WH, et al. Clonal development, stem-cell differentiation, and clinical remissions in acute nonlymphocytic leukemia. N Engl J Med 1987;317:468-73.
    • (1987) N Engl J Med , vol.317 , pp. 468-473
    • Fialkow, P.J.1    Singer, J.W.2    Raskind, W.H.3
  • 13
    • 0028091194 scopus 로고
    • A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
    • LapidotT, Sirard C, Vormoor J, et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 1994;367:645-8.
    • (1994) Nature , vol.367 , pp. 645-648
    • Lapidot, T.1    Sirard, C.2    Vormoor, J.3
  • 15
    • 0017605839 scopus 로고
    • Nuclear labelling of leukaemic blast cells with tritiated thymidine triphosphate in 35 patients with acut leukaemia
    • Wantzin GL. Nuclear labelling of leukaemic blast cells with tritiated thymidine triphosphate in 35 patients with acut leukaemia. Br J Haematol 1977;37:475-82.
    • (1977) Br J Haematol , vol.37 , pp. 475-482
    • Wantzin, G.L.1
  • 16
    • 78651158197 scopus 로고
    • A stochastic model of stem cell proliferation, based on the growth of spleen colony-forming cells
    • Till JE, McCulloch EA, Siminovitch L. A stochastic model of stem cell proliferation, based on the growth of spleen colony-forming cells. Proc Natl Acad Sci U S A 1964;51:29-36.
    • (1964) Proc Natl Acad Sci U S A , vol.51 , pp. 29-36
    • Till, J.E.1    McCulloch, E.A.2    Siminovitch, L.3
  • 18
    • 0141483064 scopus 로고    scopus 로고
    • Normal and leukemic hematopoiesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?
    • Passegue E, Jamieson CH, Ailles LE, Weissman IL. Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics? Proc Natl Acad Sci U S A 2003;100 Suppl 1:11842-9.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.SUPPL. 1 , pp. 11842-11849
    • Passegue, E.1    Jamieson, C.H.2    Ailles, L.E.3    Weissman, I.L.4
  • 19
    • 4644341516 scopus 로고    scopus 로고
    • Discontinuation of imatinib therapy after achieving a molecular response
    • Cortes J, O'Brien S, Kantarjian H. Discontinuation of imatinib therapy after achieving a molecular response. Blood 2004;104:2204-5.
    • (2004) Blood , vol.104 , pp. 2204-2205
    • Cortes, J.1    O'Brien, S.2    Kantarjian, H.3
  • 20
    • 0028018343 scopus 로고
    • Persistence of dormant leukemic progenitors during interferon-induced remission in chronic myelogenous leukemia. Analysis by polymerase chain reaction of individual colonies
    • Talpaz M, Estrov Z, Kantarjian H, Ku S, Foteh A, Kurzrock R. Persistence of dormant leukemic progenitors during interferon-induced remission in chronic myelogenous leukemia. Analysis by polymerase chain reaction of individual colonies. J Clin Invest 1994;94:1383-9.
    • (1994) J Clin Invest , vol.94 , pp. 1383-1389
    • Talpaz, M.1    Estrov, Z.2    Kantarjian, H.3    Ku, S.4    Foteh, A.5    Kurzrock, R.6
  • 21
    • 0033135248 scopus 로고    scopus 로고
    • Should polymerase chain reaction analysis to detect minimal residual disease in patients with chronic myelogenous leukemia be used in clinical decision making?
    • Faderl S, Talpaz M, Kantarjian HM, Estrov Z. Should polymerase chain reaction analysis to detect minimal residual disease in patients with chronic myelogenous leukemia be used in clinical decision making? Blood 1999;93:2755-9.
    • (1999) Blood , vol.93 , pp. 2755-2759
    • Faderl, S.1    Talpaz, M.2    Kantarjian, H.M.3    Estrov, Z.4
  • 22
    • 0033136719 scopus 로고    scopus 로고
    • Self-renewal, differentiation or death: Regulation and manipulation of hematopoietic stem cell fate
    • Domen J, Weissman IL. Self-renewal, differentiation or death: regulation and manipulation of hematopoietic stem cell fate. Mol Med Today 1999;5:201-8.
    • (1999) Mol Med Today , vol.5 , pp. 201-208
    • Domen, J.1    Weissman, I.L.2
  • 23
    • 0034712022 scopus 로고    scopus 로고
    • Translating stem and progenitor cell biology to the clinic: Barriers and opportunities
    • Weissman IL. Translating stem and progenitor cell biology to the clinic: barriers and opportunities. Science 2000;287:1442-6.
    • (2000) Science , vol.287 , pp. 1442-1446
    • Weissman, I.L.1
  • 25
    • 0029958876 scopus 로고    scopus 로고
    • Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
    • Goodell MA, Brose K, Paradis G, Conner AS, Mulligan RC. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med 1996;183:1797-806.
    • (1996) J Exp Med , vol.183 , pp. 1797-1806
    • Goodell, M.A.1    Brose, K.2    Paradis, G.3    Conner, A.S.4    Mulligan, R.C.5
  • 26
    • 20344379437 scopus 로고    scopus 로고
    • Somatic stem cell marker prominin-1/CD133 is expressed in embryonic stem cell-derived progenitors
    • Kania G, Corbeil D, Fuchs J, et al. Somatic stem cell marker prominin-1/CD133 is expressed in embryonic stem cell-derived progenitors. Stem Cells 2005;23:791-804.
    • (2005) Stem Cells , vol.23 , pp. 791-804
    • Kania, G.1    Corbeil, D.2    Fuchs, J.3
  • 27
    • 19944426498 scopus 로고    scopus 로고
    • Rapid reconstitution of dendritic cells after allogeneic transplantation of CD133+ selected hematopoietic stem cells
    • Bornhauser M, Eger L, Oelschlaegel U, et al. Rapid reconstitution of dendritic cells after allogeneic transplantation of CD133+ selected hematopoietic stem cells. Leukemia 2005;19:161-5.
    • (2005) Leukemia , vol.19 , pp. 161-165
    • Bornhauser, M.1    Eger, L.2    Oelschlaegel, U.3
  • 28
    • 21244463426 scopus 로고    scopus 로고
    • SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
    • Kiel MJ, Yilmaz OH, Iwashita T, Terhorst C, Morrison SJ. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 2005;121:1109-21.
    • (2005) Cell , vol.121 , pp. 1109-1121
    • Kiel, M.J.1    Yilmaz, O.H.2    Iwashita, T.3    Terhorst, C.4    Morrison, S.J.5
  • 29
    • 0033529756 scopus 로고    scopus 로고
    • Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activity
    • Storms RW, Trujillo AP, Springer JB, et al. Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activity. Proc Natl Acad Sci U S A 1999;96:9118-23.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 9118-9123
    • Storms, R.W.1    Trujillo, A.P.2    Springer, J.B.3
  • 30
    • 4444225475 scopus 로고    scopus 로고
    • Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity
    • Hess DA, Meyerrose TE, Wirthlin L, et al. Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity. Blood 2004;104:1648-55.
    • (2004) Blood , vol.104 , pp. 1648-1655
    • Hess, D.A.1    Meyerrose, T.E.2    Wirthlin, L.3
  • 31
    • 0030988803 scopus 로고    scopus 로고
    • Lack of expression of Thy-1 (CD90) on acute myeloid leukemia cells with long-term proliferative ability in vitro and in vivo
    • Blair A, Hogge DE, Ailles LE, Lansdorp PM, Sutherland HJ. Lack of expression of Thy-1 (CD90) on acute myeloid leukemia cells with long-term proliferative ability in vitro and in vivo. Blood 1997;89:3104-12.
    • (1997) Blood , vol.89 , pp. 3104-3112
    • Blair, A.1    Hogge, D.E.2    Ailles, L.E.3    Lansdorp, P.M.4    Sutherland, H.J.5
  • 32
    • 0034097928 scopus 로고    scopus 로고
    • Primitive acute myeloid leukemia cells with long-term proliferative ability in vitro and in vivo lack surface expression of c-kit (CD117)
    • Blair A, Sutherland HJ. Primitive acute myeloid leukemia cells with long-term proliferative ability in vitro and in vivo lack surface expression of c-kit (CD117). Exp Hematol 2000;28:660-71.
    • (2000) Exp Hematol , vol.28 , pp. 660-671
    • Blair, A.1    Sutherland, H.J.2
  • 33
    • 0033815950 scopus 로고    scopus 로고
    • The interleukin-3 receptor α chain is a unique marker for human acute myelogenous leukemia stem cells
    • Jordan CT, Upchurch D, Szilvassy SJ, et al. The interleukin-3 receptor α chain is a unique marker for human acute myelogenous leukemia stem cells. Leukemia 2000;14:1777-84.
    • (2000) Leukemia , vol.14 , pp. 1777-1784
    • Jordan, C.T.1    Upchurch, D.2    Szilvassy, S.J.3
  • 34
    • 0032745463 scopus 로고    scopus 로고
    • Detection of cytogenetic aberrations both in CD90 (Thy-1)-positive and (Thy-1)-negative stem cell (CD34) subfractions of patients with acute and chronic myeloid leukemias
    • Brendel C, Mohr B, Schimmelpfennig C, et al. Detection of cytogenetic aberrations both in CD90 (Thy-1)-positive and (Thy-1)-negative stem cell (CD34) subfractions of patients with acute and chronic myeloid leukemias. Leukemia 1999;13:1770-5.
    • (1999) Leukemia , vol.13 , pp. 1770-1775
    • Brendel, C.1    Mohr, B.2    Schimmelpfennig, C.3
  • 35
    • 0037737728 scopus 로고    scopus 로고
    • A role for Wnt signalling in self-renewal of haematopoietic stem cells
    • Reya T, Duncan AW, Ailles L, et al. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature 2003;423:409-14.
    • (2003) Nature , vol.423 , pp. 409-414
    • Reya, T.1    Duncan, A.W.2    Ailles, L.3
  • 36
    • 0029912546 scopus 로고    scopus 로고
    • Longterm leukemia-initiating capacity of a CD34- sub-population of acute myeloid leukemia
    • Terpstra W, Prins A, Ploemacher RE, et al. Longterm leukemia-initiating capacity of a CD34- sub-population of acute myeloid leukemia. Blood 1996;87:2187-94.
    • (1996) Blood , vol.87 , pp. 2187-2194
    • Terpstra, W.1    Prins, A.2    Ploemacher, R.E.3
  • 37
    • 1542398821 scopus 로고    scopus 로고
    • Acute promyelocytic leukemia: Where does it stem from?
    • Grimwade D, Enver T. Acute promyelocytic leukemia: where does it stem from? Leukemia 2004;18:375-84.
    • (2004) Leukemia , vol.18 , pp. 375-384
    • Grimwade, D.1    Enver, T.2
  • 38
    • 0034595656 scopus 로고    scopus 로고
    • The genetic program of hematopoietic stem cells
    • Phillips RL, Ernst RE, Brunk B, et al. The genetic program of hematopoietic stem cells. Science 2000;288:1635-40.
    • (2000) Science , vol.288 , pp. 1635-1640
    • Phillips, R.L.1    Ernst, R.E.2    Brunk, B.3
  • 41
    • 7644243641 scopus 로고    scopus 로고
    • The nature of stem cells: State rather than entity
    • Zipori D. The nature of stem cells: state rather than entity. Nat Rev Genet 2004;5:873-8.
    • (2004) Nat Rev Genet , vol.5 , pp. 873-878
    • Zipori, D.1
  • 43
    • 0037071391 scopus 로고    scopus 로고
    • Hematopoietic cytokines, transcription factors and lineage commitment
    • Zhu J, Emerson SG. Hematopoietic cytokines, transcription factors and lineage commitment. Oncogene 2002;21:3295-313.
    • (2002) Oncogene , vol.21 , pp. 3295-3313
    • Zhu, J.1    Emerson, S.G.2
  • 44
    • 10044268658 scopus 로고    scopus 로고
    • Molecular pathways regulating the self-renewal of hematopoietic stem cells
    • Stein MI, Zhu J, Emerson SG. Molecular pathways regulating the self-renewal of hematopoietic stem cells. Exp Hematol 2004;32:1129-36.
    • (2004) Exp Hematol , vol.32 , pp. 1129-1136
    • Stein, M.I.1    Zhu, J.2    Emerson, S.G.3
  • 45
    • 0033135847 scopus 로고    scopus 로고
    • The SCL gene: From case report to critical hematopoietic regulator
    • Begley CG, Green AR. The SCL gene: from case report to critical hematopoietic regulator. Blood 1999;93:2760-70.
    • (1999) Blood , vol.93 , pp. 2760-2770
    • Begley, C.G.1    Green, A.R.2
  • 46
    • 6044275816 scopus 로고    scopus 로고
    • SCL: From the origin of hematopoiesis to stem cells and leukemia
    • Lecuyer E, Hoang T. SCL: from the origin of hematopoiesis to stem cells and leukemia. Exp Hematol 2004;32:11-24.
    • (2004) Exp Hematol , vol.32 , pp. 11-24
    • Lecuyer, E.1    Hoang, T.2
  • 47
    • 0035839843 scopus 로고    scopus 로고
    • AML1 and the AML1-ETO fusion protein in the pathogenesis of t(8;21) AML
    • Licht JD. AML1 and the AML1-ETO fusion protein in the pathogenesis of t(8;21) AML. Oncogene 2001;20:5660-79.
    • (2001) Oncogene , vol.20 , pp. 5660-5679
    • Licht, J.D.1
  • 49
    • 0036317908 scopus 로고    scopus 로고
    • Hematopoietic stem cell expansion and distinct myeloid developmental abnormalities in a murine model of the AML1-ETO translocation
    • de Guzman CG, Warren AJ, Zhang Z, et al. Hematopoietic stem cell expansion and distinct myeloid developmental abnormalities in a murine model of the AML1-ETO translocation. Mol Cell Biol 2002;22:5506-17.
    • (2002) Mol Cell Biol , vol.22 , pp. 5506-5517
    • Guzman, C.G.1    Warren, A.J.2    Zhang, Z.3
  • 50
    • 0141816711 scopus 로고    scopus 로고
    • NF-Ycooperates with USF1/2 to induce the hematopoietic expression of HOXB4
    • Zhu J, Giannola DM, Zhang Y, Rivera AJ, Emerson SG. NF-Ycooperates with USF1/2 to induce the hematopoietic expression of HOXB4. Blood 2003;102:2420-7.
    • (2003) Blood , vol.102 , pp. 2420-2427
    • Zhu, J.1    Giannola, D.M.2    Zhang, Y.3    Rivera, A.J.4    Emerson, S.G.5
  • 51
    • 0029091845 scopus 로고
    • Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo
    • Sauvageau G, Thorsteinsdottir U, Eaves CJ, et al. Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo. Genes Dev 1995;9:1753-65.
    • (1995) Genes Dev , vol.9 , pp. 1753-1765
    • Sauvageau, G.1    Thorsteinsdottir, U.2    Eaves, C.J.3
  • 52
    • 0033569406 scopus 로고    scopus 로고
    • Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
    • Golub TR, Slonim DK, Tamayo P, et al. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 1999;286:531-7.
    • (1999) Science , vol.286 , pp. 531-537
    • Golub, T.R.1    Slonim, D.K.2    Tamayo, P.3
  • 53
    • 0032715662 scopus 로고    scopus 로고
    • Frequent co-expression of the HOXA9 and MEIS1 homeobox genes in human myeloid leukemias
    • Lawrence HJ, Rozenfeld S, Cruz C, et al. Frequent co-expression of the HOXA9 and MEIS1 homeobox genes in human myeloid leukemias. Leukemia 1999;13:1993-9.
    • (1999) Leukemia , vol.13 , pp. 1993-1999
    • Lawrence, H.J.1    Rozenfeld, S.2    Cruz, C.3
  • 54
    • 11244305618 scopus 로고    scopus 로고
    • WNT signalling and haematopoiesis: A WNT-WNTsituation
    • Staal FJ, Clevers HC. WNT signalling and haematopoiesis: a WNT-WNTsituation. Nat Rev lmmunol 2005:5:21-30.
    • (2005) Nat Rev Lmmunol , vol.5 , pp. 21-30
    • Staal, F.J.1    Clevers, H.C.2
  • 55
    • 20144370145 scopus 로고    scopus 로고
    • Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance
    • Duncan AW, Rattis FM, DiMascio LN, et al. Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance. Nat Immunol 2005;6:314-22.
    • (2005) Nat Immunol , vol.6 , pp. 314-322
    • Duncan, A.W.1    Rattis, F.M.2    Dimascio, L.N.3
  • 56
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: Cell fate control and signal integration in development
    • Artavanis-Tsakonas S, Rand MD, Lake RJ. Notch signaling: cell fate control and signal integration in development. Science 1999;284:770-6.
    • (1999) Science , vol.284 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 57
    • 20244389684 scopus 로고    scopus 로고
    • Notch1 expression in early lymphopoiesis influences B versusT lineage determination
    • Pui JC, Allman D, Xu L, et al. Notch1 expression in early lymphopoiesis influences B versusT lineage determination. Immunity 1999;11:299-308.
    • (1999) Immunity , vol.11 , pp. 299-308
    • Pui, J.C.1    Allman, D.2    Xu, L.3
  • 58
    • 0025856717 scopus 로고
    • TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
    • Ellisen LW, Bird J, West DC, et al. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 1991;66:649-61.
    • (1991) Cell , vol.66 , pp. 649-661
    • Ellisen, L.W.1    Bird, J.2    West, D.C.3
  • 59
    • 0030218039 scopus 로고    scopus 로고
    • The Polycomb-group homolog Bmi-1 is a regulator of murine Hox gene expression
    • van der Lugt NM, Alkema M, Berns A, Deschamps J. The Polycomb-group homolog Bmi-1 is a regulator of murine Hox gene expression. Mech Dev 1996;58:153-64.
    • (1996) Mech Dev , vol.58 , pp. 153-164
    • Lugt, N.M.1    Alkema, M.2    Berns, A.3    Deschamps, J.4
  • 60
    • 0035902140 scopus 로고    scopus 로고
    • The Hedgehog and Wnt signalling pathways in cancer
    • Taipale J, Beachy PA. The Hedgehog and Wnt signalling pathways in cancer. Nature 2001;411:349-54.
    • (2001) Nature , vol.411 , pp. 349-354
    • Taipale, J.1    Beachy, P.A.2
  • 61
    • 0032519809 scopus 로고    scopus 로고
    • Stage-specific expression of polycomb group genes in human bone marrow cells
    • Lessard J, Baban S, Sauvageau G. Stage-specific expression of polycomb group genes in human bone marrow cells. Blood 1998;91:1216-24.
    • (1998) Blood , vol.91 , pp. 1216-1224
    • Lessard, J.1    Baban, S.2    Sauvageau, G.3
  • 62
    • 0038349957 scopus 로고    scopus 로고
    • Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells
    • Park IK, Qian D, Kiel M, et al. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature 2003;423:302-5.
    • (2003) Nature , vol.423 , pp. 302-305
    • Park, I.K.1    Qian, D.2    Kiel, M.3
  • 63
    • 0037673984 scopus 로고    scopus 로고
    • Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
    • Lessard J, Sauvageau G. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 2003;423:255-60.
    • (2003) Nature , vol.423 , pp. 255-260
    • Lessard, J.1    Sauvageau, G.2
  • 64
    • 0035257660 scopus 로고    scopus 로고
    • Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation
    • Bhardwaj G, Murdoch B, Wu D, et al. Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation. Nat Immunol 2001;2:172-80.
    • (2001) Nat Immunol , vol.2 , pp. 172-180
    • Bhardwaj, G.1    Murdoch, B.2    Wu, D.3
  • 65
    • 0037606054 scopus 로고    scopus 로고
    • Detection, isolation, and stimulation of quiescent primitive leukemic progenitor cells from patients with acute myeloid leukemia (AML)
    • Guan Y, Gerhard B, Hogge DE. Detection, isolation, and stimulation of quiescent primitive leukemic progenitor cells from patients with acute myeloid leukemia (AML). Blood 2003;101:3142-9.
    • (2003) Blood , vol.101 , pp. 3142-3149
    • Guan, Y.1    Gerhard, B.2    Hogge, D.E.3
  • 66
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • Dean M, Fojo T, Bates S. Tumour stem cells and drug resistance. Nat Rev Cancer 2005;5:275-84.
    • (2005) Nat Rev Cancer , vol.5 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3
  • 67
    • 0036040031 scopus 로고    scopus 로고
    • Theanti-apoptotic genes BcI-X(L) and Bcl-2 are over-expressed and contribute to chemoresistance of non-proliferating leukaemic CD34+ cells
    • Konopleva M, ZhaoS, Hu W.etl.Theanti-apoptotic genes BcI-X(L) and Bcl-2 are over-expressed and contribute to chemoresistance of non-proliferating leukaemic CD34+ cells. Br J Haematol 2002;118:521-34.
    • (2002) Br J Haematol , vol.118 , pp. 521-534
    • Konopleva, M.1    Zhao, S.2    Hu, W.3
  • 68
    • 0025799513 scopus 로고
    • Expression and actinity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells
    • Chaudhary PM, Roninson IB. Expression and actinity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells. Cell 1991;66:85-94.
    • (1991) Cell , vol.66 , pp. 85-94
    • Chaudhary, P.M.1    Roninson, I.B.2
  • 69
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of ATP-dependent transporters
    • Gottesman MM, Fojo T, Bates SE. Multidrug resistance in cancer: role of ATP-dependent transporters. Nat Rev Cancer 2002;2:48-58.
    • (2002) Nat Rev Cancer , vol.2 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 70
    • 0037079708 scopus 로고    scopus 로고
    • Torok-Storb B. The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors
    • Scharenberg CW, Harkey MA. Torok-Storb B. The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors. Blood 2002:99:507-12.
    • (2002) Blood , vol.99 , pp. 507-512
    • Scharenberg, C.W.1    Harkey, M.A.2
  • 71
    • 0035877989 scopus 로고    scopus 로고
    • Hoechst 33342 efflux identifies a subpopulation of cytogenetically normal CD34 (+) CD38 (-) progenitor cells from patients with acutemyeloid leukemia
    • Feuring-Buske M, Hogge DE. Hoechst 33342 efflux identifies a subpopulation of cytogenetically normal CD34 (+) CD38 (-) progenitor cells from patients with acutemyeloid leukemia. Blood 2001;97:3882-9.
    • (2001) Blood , vol.97 , pp. 3882-3889
    • Feuring-Buske, M.1    Hogge, D.E.2
  • 72
    • 0034525530 scopus 로고    scopus 로고
    • Proliferative status of primitive hematopoietic progenitors from patients with acute myelogenous leukemia (AML)
    • Guan Y, Hogge DE. Proliferative status of primitive hematopoietic progenitors from patients with acute myelogenous leukemia (AML). Leukemia 2000;14:2135-41.
    • (2000) Leukemia , vol.14 , pp. 2135-2141
    • Guan, Y.1    Hogge, D.E.2
  • 73
    • 0032700495 scopus 로고    scopus 로고
    • Retrovtral marking of acute myelogenous leukemia progenitors that initiate long-term culture and growth in immunodeficient mice
    • Ailles LE, Humphries RK, Thomas TE, Hogge DE. Retrovtral marking of acute myelogenous leukemia progenitors that initiate long-term culture and growth in immunodeficient mice. Exp Hematol 1999;27:1609-20.
    • (1999) Exp Hematol , vol.27 , pp. 1609-1620
    • Ailles, L.E.1    Humphries, R.K.2    Thomas, T.E.3    Hogge, D.E.4
  • 74
    • 0029840432 scopus 로고    scopus 로고
    • Fluorouracil selectively spares acute myeloid leukemia cells with long-term growth abilities in immunodeficient mice and in culture
    • Terpstra W, Ploemacher RE, Prins A, et al. Fluorouracil selectively spares acute myeloid leukemia cells with long-term growth abilities in immunodeficient mice and in culture. Blood 1996;88:1944-50.
    • (1996) Blood , vol.88 , pp. 1944-1950
    • Terpstra, W.1    Ploemacher, R.E.2    Prins, A.3
  • 75
    • 0035886024 scopus 로고    scopus 로고
    • Nuclear factor-κB is constitutively activated in primitive human acute myelogenous leukemia cells
    • Guzman ML, Neering SJ, Upchurch D, et al. Nuclear factor-κB is constitutively activated in primitive human acute myelogenous leukemia cells. Blood 2001;98:2301-7.
    • (2001) Blood , vol.98 , pp. 2301-2307
    • Guzman, M.L.1    Neering, S.J.2    Upchurch, D.3
  • 76
    • 0033568250 scopus 로고    scopus 로고
    • Isolation of a highly quiescent subpopulation of primitive leukemic cells in chronic myeloid leukemia
    • Holyoake T Jiang X, Eaves C, Eaves A. Isolation of a highly quiescent subpopulation of primitive leukemic cells in chronic myeloid leukemia. Blood 1999;94:2056-64.
    • (1999) Blood , vol.94 , pp. 2056-2064
    • Holyoake, T.1    Jiang, X.2    Eaves, C.3    Eaves, A.4
  • 77
    • 14944367962 scopus 로고    scopus 로고
    • Detection of BCR-ABL kinase mutations in CD34+ cells from chronic myelogenous leukemia patients in complete cytogenetic remission on imatinib mesylate treatment
    • Chu S, Xu H, Shah NP, et al. Detection of BCR-ABL kinase mutations in CD34+ cells from chronic myelogenous leukemia patients in complete cytogenetic remission on imatinib mesylate treatment. Blood 2005;105:2093-8.
    • (2005) Blood , vol.105 , pp. 2093-2098
    • Chu, S.1    Xu, H.2    Shah, N.P.3
  • 78
    • 0035760302 scopus 로고    scopus 로고
    • Benefit of cyclosporine modulation of drug resistance in patients with poor-risk acute myeloid leukemia: A Southwest Oncology Group study
    • List AF, Kopecky KJ, Willman CL, et al. Benefit of cyclosporine modulation of drug resistance in patients with poor-risk acute myeloid leukemia: a Southwest Oncology Group study. Blood 2001;98:3212-20.
    • (2001) Blood , vol.98 , pp. 3212-3220
    • List, A.F.1    Kopecky, K.J.2    Willman, C.L.3
  • 79
    • 0037103189 scopus 로고    scopus 로고
    • Phase 3 study of the multidrug resistance modulator PSC-833 in previously untreated patients 60 years of age and older with acute myeloid leukemia: Cancer and Leukemia Group B Study 9720
    • Baer MR, George SL, Dodge RK, et al. Phase 3 study of the multidrug resistance modulator PSC-833 in previously untreated patients 60 years of age and older with acute myeloid leukemia: Cancer and Leukemia Group B Study 9720. Blood 2002;100:1224-32.
    • (2002) Blood , vol.100 , pp. 1224-1232
    • Baer, M.R.1    George, S.L.2    Dodge, R.K.3
  • 80
    • 6044234531 scopus 로고    scopus 로고
    • Mechanisms controlling pathogenesis and survival of leukemic stem cells
    • Jordan CT, Guzman ML Mechanisms controlling pathogenesis and survival of leukemic stem cells. Oncogene 2004;23:7178-87.
    • (2004) Oncogene , vol.23 , pp. 7178-7187
    • Jordan, C.T.1    Guzman, M.L.2
  • 81
    • 0037059012 scopus 로고    scopus 로고
    • Preferential induction of apoptosis for primary human leukemic stem cells
    • Guzman ML, Swiderski CF, Howard DS, et al. Preferential induction of apoptosis for primary human leukemic stem cells. Proc Natl Acad Sci U S A 2002;99:16220-5.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 16220-16225
    • Guzman, M.L.1    Swiderski, C.F.2    Howard, D.S.3
  • 82
    • 16844363378 scopus 로고    scopus 로고
    • The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells
    • Guzman ML, Rossi RM, Karnischky L, et al. The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells. Blood 2005;105:4163-9.
    • (2005) Blood , vol.105 , pp. 4163-4169
    • Guzman, M.L.1    Rossi, R.M.2    Karnischky, L.3
  • 83
    • 0042744837 scopus 로고    scopus 로고
    • Survival of acute myeloid leukemia cells requires P13 kinase activation
    • Xu Q, Simpson SE, Scialla TJ, Bagg A, Carroll M. Survival of acute myeloid leukemia cells requires P13 kinase activation. Blood 2003;102:972-80.
    • (2003) Blood , vol.102 , pp. 972-980
    • Xu, Q.1    Simpson, S.E.2    Scialla, T.J.3    Bagg, A.4    Carroll, M.5
  • 84
    • 0029975914 scopus 로고    scopus 로고
    • Expression of megakaryocytic and erythroid properties in human leukemic cells
    • Tani T, Ylanne J, Virtanen I. Expression of megakaryocytic and erythroid properties in human leukemic cells. Exp Hematol 1996;24:158-68.
    • (1996) Exp Hematol , vol.24 , pp. 158-168
    • Tani, T.1    Ylanne, J.2    Virtanen, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.