NF-Y cooperates with USF1/2 to induce the hematopoietic expression of HOXB4

Blood

Volumn 102, Issue 7, 2003, Pages 2420-2427

  Zhu, Jiang ^b   Giannola, Diane M ^b   Zhang, Yi ^b   Rivera, Adam J ^b   Emerson, Stephen G ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

HOX RESPONSE ELEMENT 1; HOX RESPONSE ELEMENT 2; NUCLEAR FACTOR Y; PROTEIN; PROTEIN HOXB4; PROTEIN SUBUNIT; STEM CELL FACTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; UPSTREAM STIMULATORY FACTOR 1; UPSTREAM STIMULATORY FACTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; COMPLEX FORMATION; CONTROLLED STUDY; DNA BINDING; EMBRYO; GENETIC TRANSCRIPTION; HEMATOPOIESIS; HEMATOPOIETIC CELL; HOMEOBOX; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION;

EID: 0141816711     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2003-01-0251     Document Type: Article

References (31)

1. McGinnis W, Krumlauf R. Homeobox genes and axial patterning. Cell. 1992;68:283-302.
2. Vieille-Grosjean I, Roullot V, Courtois G. Identification of homeobox-containing genes expressed in hematopoietic blast cells. Biochem Biophys Res Commun. 1992;185:785-792.
3. Sauvageau G, Lansdorp PM, Eaves CJ, et al. Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells. Proc Natl Acad Sci U S A. 1994;91:12223-12227.
4. Giampaolo A, Sterpetti P, Bulgarini D, et al. Key functional role and lineage-specific expression of selected HOXB genes in purified hematopoietic progenitor differentiation. Blood. 1994;84:3637-3647.
5. Sauvageau G, Thorsteinsdottir U, Eaves CJ, et al. Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo. Genes Dev. 1995;9:1753-1765.
6. Antonchuk J, Sauvageau G, Humphries RK. HOXB4-induced expansion of adult hematopoietic stem cells ex vivo. Cell. 2002;109:39-45.
7. Kyba M, Perlingeiro RC, Daley GQ. HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors. Cell. 2002;109:29-37.
8. Schiedlmeier B, Klump H, Will E, et al. High-level ectopic HOXB4 expression confers a profound in vivo competitive growth advantage to human cord blood CD34+ cells, but impairs lymphomyeloid differentiation. Blood. 2003;101:1759-1768.
9. Pan Q, Simpson RU. Antisense knockout of HOXB4 blocks 1,25-dihydroxyvitamin D3 inhibition of c-myc expression. J Endocrinol. 2001;169:153-159.
10. Pan Q, Simpson RU. c-myc intron element-binding proteins are required for 1,25-dihydroxyvitamin D3 regulation of c-myc during HL-60 cell differentiation and the involvement of HOXB4. J Biol Chem. 1999;274:8437-8444.
11. Gutman A, Gilthorpe J, Rigby PW. Multiple positive and negative regulatory elements in the promoter of the mouse homeobox gene Hoxb-4. Mol Cell Biol. 1994;14:8143-8154.
12. Giannola DM, Shlomchik WD, Jegathesan M, et al. Hematopoietic expression of HOXB4 is regulated in normal and leukemic stem cells through transcriptional activation of the HOXB4 promoter by upstream stimulating factor (USF)-1 and USF-2. J Exp Med. 2000;192:1479-1490.
13. Mantovani R, Li XY, Pessara U, Hooft van Huisjduijnen R, Benoist C, Mathis D. Dominant negative analogs of NF-YA. J Biol Chem. 1994;269:20340-20346.
14. Pui JC, Allman D, Xu L, et al. Notch1 expression in early lymphopoiesis influences B versus T lineage determination. Immunity. 1999;11:299-308.
15. Kuo MH, Allis CD. In vivo cross-linking and immunoprecipitation for studying dynamic protein:DNA associations in a chromatin environment. Methods. 1999;19:425-433.
16. Orlando V. Mapping chromosomal proteins in vivo by formaldehyde-crosslinked-chromatin immunoprecipitation. Trends Biochem Sci. 2000;25:99-104.
17. Mantovani R. The molecular biology of the CCAAT-binding factor NF-Y. Gene. 1999;239:15-27.
18. Smith LT, Hohaus S, Gonzalez DA, Dziennis SE, Tenen DG. PU.1 (Spi-1) and C/EBP alpha regulate the granulocyte colony-stimulating factor receptor promoter in myeloid cells. Blood. 1996;88:1234-1247.
19. Marziali G, Perretti E, Ilari R, et al. The activity of the CCAAT-box binding factor NF-Y is modulated through the regulated expression of its A subunit during monocyte to macrophage differentiation: regulation of tissue-specific genes through a ubiquitous transcription factor. Blood. 1999;93:519-526.
20. Matuoka K, Yu Chen K. Nuclear factor Y (NF-Y) and cellular senescence. Exp Cell Res. 1999;253:365-371.
21. Zemzoumi K, Frontini M, Bellorini M, Mantovani R. NF-Y histone fold alphal helices help impart CCAAT specificity. J Mol Biol. 1999;286:327-337.
22. Radomska HS, Satterthwaite AB, Taranenko N, Narravula S, Krause DS, Tenen DG. A nuclear factor Y (N FY) site positively regulates the human CD34 stem cell gene. Blood. 1999;94:3772-3780.
23. Jabrane-Ferrat N, Nekrep N, Tosi G, Esserman LJ, Peterlin BM. Major histocompatibility complex class II transcriptional platform: assembly of nuclear factor Y and regulatory factor X (RFX) on DNA requires RFX5 dimers. Mol Cell Biol. 2002;22:5616-5625.
24. Xu Y, Banville D, Zhao HF, Zhao X, Shen SH. Transcriptional activity of the SHP-1. gene in MCF7 cells is differentially regulated by binding of NF-Y factor to two distinct CCAAT-elements. Gene. 2001;269:141-153.
25. Gilthorpe J, Vandromme M, Brend T, et al. Spatially specific expression of Hoxb4 is dependent on the ubiquitous transcdption factor NFY. Development. 2002;129:3887-3899.
26. Ivanova NB, Dimos JT, Schaniel C, Hackney JA, Moore KA, Lemischka IR. A stem cell molecular signature. Science. 2002;298:601-604.
27. Sjin RM, Krishnaraju K, Hoffman B, Liebermann DA. Transcriptional regulation of myeloid differentiation primary response (MyD) genes during myeloid differentiation is mediated by nuclear factor Y. Blood. 2002;100:80-88.
28. Bjomsson J, Brun A, Karlsson S. The stem cell pool in Hoxb4-/- and Hoxb3/Hoxb4-/-mice is reduced due to insufficient expression in the fetal liver [abstract]. Blood. 2002;100:129a.
29. Daga A, Podesta M, Capra MC, Piaggio G, Frassoni F, Corte G. The retroviral transduction of HOXC4 into human CD34(+) cells induces an in vitro expansion of clonogenic and early progenitors. Exp Hematol. 2000;28:569-574.
30. Folberg A, Nagy Kovacs E, Luo J, Giguere V, Featherstone M. RARbeta mediates the response of Hoxd4 and Hoxb4 to exogenous retinoic acid. Dev Dyn. 1999;215:96-107.
31. Stathopoulos A, Van Drenth M, Erives A, Markstein M, Levine M. Whole-genome analysis of dorsal-ventral patterning in the Drosophila embryo. Cell. 2002;111:687-701.