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Volumn 27, Issue 4, 2005, Pages 167-176

Cardiovascular effects of Leptin;Lepti̇ni̇n kardi̇yovasküler etki̇leri̇

Author keywords

Cardiovascular diseases; Hypertension; Leptin; Obesity; Sympathetic nervous system

Indexed keywords

LEPTIN; LEPTIN RECEPTOR;

EID: 31444453162     PISSN: 1300199X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (2)

References (53)
  • 1
    • 2342538411 scopus 로고    scopus 로고
    • Leptin and hyperleptinemia-from friend to foe for cardiovascular function
    • J.Ren. Leptin and hyperleptinemia-from friend to foe for cardiovascular function. J Endocrin 2004; 181: 1-10.
    • (2004) J Endocrin , vol.181 , pp. 1-10
    • Ren, J.1
  • 2
    • 31444453037 scopus 로고    scopus 로고
    • Obesity- Associated activation of angiotensin and endothelin in the cardiovascular system
    • Bartun M, Carmona R, Ortmann J, Kneger JE et al. Obesity- associated activation of angiotensin and endothelin in the cardiovascular system. IJ BCB, 2003; 3: 826-837.
    • (2003) IJ BCB , vol.3 , pp. 826-837
    • Bartun, M.1    Carmona, R.2    Ortmann, J.3    Kneger, J.E.4
  • 5
    • 0005798092 scopus 로고    scopus 로고
    • Adenoviral leptin as gene therapy for obesity related hypertension
    • Abstract
    • Zhang W, Telemague-Potts S, Andersan PR, Wang Z. et al. Adenoviral leptin as gene therapy for obesity related hypertension. Am J Hypertens 2002; 15: 1A (Abstract).
    • (2002) Am J Hypertens , vol.15
    • Zhang, W.1    Telemague-Potts, S.2    Andersan, P.R.3    Wang, Z.4
  • 6
    • 0036790520 scopus 로고    scopus 로고
    • The function of leptin in nutrition, weight and physiology
    • Friedmen JM. The function of leptin in nutrition, weight and physiology, Nutr Rev 2002; 60: 51-514.
    • (2002) Nutr Rev , vol.60 , pp. 51-514
    • Friedmen, J.M.1
  • 8
    • 0030942844 scopus 로고    scopus 로고
    • The leptin receptor
    • Tartaglia LA. The leptin receptor. J Biol Chem 1997; 272: 6093-6096.
    • (1997) J Biol Chem , vol.272 , pp. 6093-6096
    • Tartaglia, L.A.1
  • 9
    • 3242657477 scopus 로고    scopus 로고
    • Leptin: Linking adipocite metabolism with cardiovascular and autoimmune disease
    • Peelman F, Waelput W, Iserentat H et al. Leptin: linking adipocite metabolism with cardiovascular and autoimmune disease . Prog Lipid Res 2003; 43: 283-301.
    • (2003) Prog Lipid Res , vol.43 , pp. 283-301
    • Peelman, F.1    Waelput, W.2    Iserentat, H.3
  • 10
    • 0030028959 scopus 로고    scopus 로고
    • Phetypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor
    • Chua SC, Chung WK Wu-Peng Xset al. Phetypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor. Science 1996; 271: 1994-1996
    • (1996) Science , vol.271 , pp. 1994-1996
    • Chua, S.C.1    Chung, W.K.2    Wu-Peng, Xs.3
  • 11
    • 0344450708 scopus 로고    scopus 로고
    • A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
    • Clement K, Vaisse C, Nahlou N et al. A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction. Nature 1998; 392: 398-401.
    • (1998) Nature , vol.392 , pp. 398-401
    • Clement, K.1    Vaisse, C.2    Nahlou, N.3
  • 12
    • 0031046730 scopus 로고    scopus 로고
    • Phenotype of the obes Koletsky(f) rat due to Tyr763Stop mutation in the extracellular domain of the leptin receptor ( Lepr): Evidence for deficient plasma-to-CSI transport of leptin in both the Zucker and Koletsky obese rat
    • Wu-Peng XS, Chua SC, Okada N, Liu SM, Nicolson M, Leibel RL. Phenotype of the obes Koletsky(f) rat due to Tyr763Stop mutation in the extracellular domain of the leptin receptor ( Lepr): evidence for deficient plasma-to-CSI transport of leptin in both the Zucker and Koletsky obese rat. Diabetes 1997; 46: 513-518.
    • (1997) Diabetes , vol.46 , pp. 513-518
    • Wu-Peng, X.S.1    Chua, S.C.2    Okada, N.3    Liu, S.M.4    Nicolson, M.5    Leibel, R.L.6
  • 13
    • 2342557919 scopus 로고    scopus 로고
    • The many lives of leptin
    • Banks WA. The many lives of leptin. Peptides 2004; 25: 331-338.
    • (2004) Peptides , vol.25 , pp. 331-338
    • Banks, W.A.1
  • 14
    • 0031761385 scopus 로고    scopus 로고
    • Expression of leptin receptor isoforms in rat brain microvessels
    • Bjorback C., Elmquist JK, Michl P et al. Expression of leptin receptor isoforms in rat brain microvessels. Endocrinology 1998; 139: 3485-3491.
    • (1998) Endocrinology , vol.139 , pp. 3485-3491
    • Bjorback, C.1    Elmquist, J.K.2    Michl, P.3
  • 15
    • 0031017561 scopus 로고    scopus 로고
    • Human blood-brain barrier leptin receptor. Binding and endocytosis in isolated human brain microvessels
    • Golden PL, Maccagnan TJ, Pardridge WM. Human blood-brain barrier leptin receptor. Binding and endocytosis in isolated human brain microvessels. J Clin Invest 1997; 99: 14-18.
    • (1997) J Clin Invest , vol.99 , pp. 14-18
    • Golden, P.L.1    Maccagnan, T.J.2    Pardridge, W.M.3
  • 16
    • 0030267744 scopus 로고    scopus 로고
    • Nonsense mutation ofleptin receptor in the obese spontaneously hypertensive Koletsky rat
    • Takaya K, Ogawa Y, Hiraoka J et al. Nonsense mutation ofleptin receptor in the obese spontaneously hypertensive Koletsky rat. Nat Genet 1996; 14: 130-131.
    • (1996) Nat Genet , vol.14 , pp. 130-131
    • Takaya, K.1    Ogawa, Y.2    Hiraoka, J.3
  • 17
    • 0037410059 scopus 로고    scopus 로고
    • Leptin-induced transactivation of NPY gene promoter mediated by JAK 1, JAK2 and STAT 3 in the neural cell lines
    • Muraoka O, Xu B, Tsurumaki T et al. Leptin-induced transactivation of NPY gene promoter mediated by JAK 1, JAK2 and STAT 3 in the neural cell lines. Neurochem Int 2003; 42: 591-601.
    • (2003) Neurochem Int , vol.42 , pp. 591-601
    • Muraoka, O.1    Xu, B.2    Tsurumaki, T.3
  • 18
    • 0037288941 scopus 로고    scopus 로고
    • Insulin and revisited: Adiposity signals with overlapping physiological and intracellular signaling capabilities
    • Niswender KD, Schwartz MW. Insulin and revisited: adiposity signals with overlapping physiological and intracellular signaling capabilities. Front Neuroendocrin 2003; 2: 1-10.
    • (2003) Front Neuroendocrin , vol.2 , pp. 1-10
    • Niswender, K.D.1    Schwartz, M.W.2
  • 19
    • 0033944103 scopus 로고    scopus 로고
    • Leptin and blood pressure-is there a link
    • Stenvinkel P. Leptin and blood pressure-is there a link. Nephrol Dial Transplant 2000; 15: 115-117.
    • (2000) Nephrol Dial Transplant , vol.15 , pp. 115-117
    • Stenvinkel, P.1
  • 21
    • 0037062657 scopus 로고    scopus 로고
    • Obesity, metabolic syndrome and coronary atherosclerosis
    • Grundy SM. Obesity, metabolic syndrome and coronary atherosclerosis. Circulation 2002; 105: 2696-2698.
    • (2002) Circulation , vol.105 , pp. 2696-2698
    • Grundy, S.M.1
  • 22
    • 0036558732 scopus 로고    scopus 로고
    • Abdominal obesity is associated with increased risk of acute coronary events in men
    • Lakka HM, Tuomilehto J, Soleman JT. Abdominal obesity is associated with increased risk of acute coronary events in men. Eur Heart J 2002; 23: 706-713.
    • (2002) Eur Heart J , vol.23 , pp. 706-713
    • Lakka, H.M.1    Tuomilehto, J.2    Soleman, J.T.3
  • 23
    • 0346849867 scopus 로고    scopus 로고
    • Obesity as a cardiovascular rise factor
    • Sowers JR. Obesity as a cardiovascular rise factor. AM J Med 2003; 115(8A): 37-41.
    • (2003) AM J Med , vol.115 , Issue.8 A , pp. 37-41
    • Sowers, J.R.1
  • 24
    • 0034096988 scopus 로고    scopus 로고
    • Plasma concentrations of a novel, adipose -specific protein , adinopectin in type 2 diabetic patients
    • Hotta K, Funahashi T, Arita Y et al. Plasma concentrations of a novel, adipose -specific protein , adinopectin in type 2 diabetic patients. Arterioscler Thromb Vase Biol 2000; 20: 1595-1599.
    • (2000) Arterioscler Thromb Vase Biol , vol.20 , pp. 1595-1599
    • Hotta, K.1    Funahashi, T.2    Arita, Y.3
  • 25
    • 0032779351 scopus 로고    scopus 로고
    • Molecular mechanism of metabolic syndrome X;contribution adipocytokines adipocyte derived bioactive substances
    • Matsuzawara Y, Funahashi T, Nakamura T. Molecular mechanism of metabolic syndrome X;contribution adipocytokines adipocyte derived bioactive substances. Ann N Y Acad Sci 1999; 892: 146-154
    • (1999) Ann N Y Acad Sci , vol.892 , pp. 146-154
    • Matsuzawara, Y.1    Funahashi, T.2    Nakamura, T.3
  • 26
    • 0036481709 scopus 로고    scopus 로고
    • Synthetic peroxisome proliferator-activated receptor- Agonist, rosiglitazone, increases plasma levels of adinopectin in type 2 diabetic patients
    • Yang WS, Jeng CY, Wu TJ et al. Synthetic peroxisome proliferator- activated receptor- agonist, rosiglitazone, increases plasma levels of adinopectin in type 2 diabetic patients. Diabetes Care 2002; 25: 376-380.
    • (2002) Diabetes Care , vol.25 , pp. 376-380
    • Yang, W.S.1    Jeng, C.Y.2    Wu, T.J.3
  • 27
    • 0032943709 scopus 로고    scopus 로고
    • C-reactive protein in healthy subjects; associations with obesity, insulin rezistance, and endothelial dysfunction. A potential for cytokines orginatingfrom adipose tissue?
    • Yudkin JS, Stehawer CDA, Emeis JJ, Coppack SW. C-reactive protein in healthy subjects; associations with obesity, insulin rezistance, and endothelial dysfunction. A potential for cytokines orginatingfrom adipose tissue?. Arterioscler Thomb Vasc Biol 1999; 19: 972-978.
    • (1999) Arterioscler Thomb Vasc Biol , vol.19 , pp. 972-978
    • Yudkin, J.S.1    Stehawer, C.D.A.2    Emeis, J.J.3    Coppack, S.W.4
  • 28
    • 0031867918 scopus 로고    scopus 로고
    • Relationship between plasma tumor necrosis factor- And insulin sensitivity in elderly men with non-insulin dependent diabetes mellitus
    • Nisson J, Jovinge S, Niemann A et al. Relationship between plasma tumor necrosis factor- and insulin sensitivity in elderly men with non-insulin dependent diabetes mellitus. Arterioscler Thomb Vasc Biol. 1998; 1, 1199-1202.
    • (1998) Arterioscler Thomb Vasc Biol , vol.1 , pp. 1199-1202
    • Nisson, J.1    Jovinge, S.2    Niemann, A.3
  • 29
    • 0034747975 scopus 로고    scopus 로고
    • Visceral fat is a determinant of PAI-1 activity in diabetic and nondiabetic ovrweight and obese women
    • Mertens I, Wander PM, Corthoust B et al. Visceral fat is a determinant of PAI-1 activity in diabetic and nondiabetic ovrweight and obese women. Horm Metab Res 2001; 33: 602-607.
    • (2001) Horm Metab Res , vol.33 , pp. 602-607
    • Mertens, I.1    Wander, P.M.2    Corthoust, B.3
  • 30
    • 4644340686 scopus 로고    scopus 로고
    • Obesity- Related hypertension: Is there a role for selective leptin resistance?
    • Correia MLG and Haynes WG. Obesity- related hypertension: Is there a role for selective leptin resistance?. Curr Hypertens Reports 2004; 6: 230-235.
    • (2004) Curr Hypertens Reports , vol.6 , pp. 230-235
    • Correia, M.L.G.1    Haynes, W.G.2
  • 31
    • 0032014178 scopus 로고    scopus 로고
    • Identification of SOCS-3 as a potential mediator of central leptin resistance
    • Bjorbaek C, Elmquist JK, Frantz JD et al. Identification of SOCS-3 as a potential mediator of central leptin resistance. Mol Cell 1998; 1: 619-625.
    • (1998) Mol Cell , vol.1 , pp. 619-625
    • Bjorbaek, C.1    Elmquist, J.K.2    Frantz, J.D.3
  • 32
    • 0033304576 scopus 로고    scopus 로고
    • Human leptin deficiency caused by a missense mutation: Multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin- Mediated defects
    • Özata M, Özdemir IC, Licinio J: Human leptin deficiency caused by a missense mutation: Multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin- mediated defects. J. Clin Endocrinal Metab. 1999; 10: 3686-3695.
    • (1999) J Clin Endocrinal Metab , vol.10 , pp. 3686-3695
    • Özata, M.1    Özdemir, I.C.2    Licinio, J.3
  • 33
    • 31444451427 scopus 로고    scopus 로고
    • Intracerebroventricular leptin increases lumbar and renal sympathetic nerve activation by leptin
    • Dunbar JC, HuY, Lu H. Intracerebroventricular leptin increases lumbar and renal sympathetic nerve activation by leptin. J Clin Invest 1997; 100: 270-278.
    • (1997) J Clin Invest , vol.100 , pp. 270-278
    • Dunbar, J.C.1    Hu, Y.2    Lu, H.3
  • 34
    • 0031606279 scopus 로고    scopus 로고
    • Chronic leptin infusion increased arterial pressure
    • Shek EW, Brands MW and Hall JE. Chronic leptin infusion increased arterial pressure. Hypertension. 1998; 31: 409-414.
    • (1998) Hypertension , vol.31 , pp. 409-414
    • Shek, E.W.1    Brands, M.W.2    Hall, J.E.3
  • 35
    • 0035100787 scopus 로고    scopus 로고
    • Leptin acts in the central nervous system to produce dose-dependent changes in arterial pressure
    • Correia ML, Morgan DA, Sivitz WI et al. Leptin acts in the central nervous system to produce dose-dependent changes in arterial pressure. Hypertension 2001; 37: 936-942.
    • (2001) Hypertension , vol.37 , pp. 936-942
    • Correia, M.L.1    Morgan, D.A.2    Sivitz, W.I.3
  • 36
    • 0032899719 scopus 로고    scopus 로고
    • Interactions between the melanocortin system and leptin in control of sympathetic nevre traffic
    • Haynes WG, Morgan DA, Djalali A et al. Interactions between the melanocortin system and leptin in control of sympathetic nevre traffic. Hypertension 1999; 33: 542-547.
    • (1999) Hypertension , vol.33 , pp. 542-547
    • Haynes, W.G.1    Morgan, D.A.2    Djalali, A.3
  • 37
    • 0036668207 scopus 로고    scopus 로고
    • Differantial modulation of leptin-inducedsympatoexcitation by baroreflex activation
    • Correia ML, Morgan DA, Chapleau MA et al. Differantial modulation of leptin-inducedsympatoexcitation by baroreflex activation. J Hypertens 2002; 20: 1633-1641.
    • (2002) J Hypertens , vol.20 , pp. 1633-1641
    • Correia, M.L.1    Morgan, D.A.2    Chapleau, M.A.3
  • 39
    • 0038460863 scopus 로고    scopus 로고
    • Neural regulation of blood pressure by leptin and the related peptides
    • Matsumura K, Tsuchihashi T, Fuji K, Lida M. Neural regulation of blood pressure by leptin and the related peptides. Regul Peptides 2003; 11: 79-86.
    • (2003) Regul Peptides , vol.11 , pp. 79-86
    • Matsumura, K.1    Tsuchihashi, T.2    Fuji, K.3    Lida, M.4
  • 40
    • 31444454717 scopus 로고    scopus 로고
    • Neuropeptide supresses action of neuropeptide Y in conscious rabbits
    • Egawa M, Yoshimatsu H, Bray GA. Neuropeptide supresses action of neuropeptide Y in conscious rabbits. Hypertension 2000; 3: 1040-1044.
    • (2000) Hypertension , vol.3 , pp. 1040-1044
    • Egawa, M.1    Yoshimatsu, H.2    Bray, G.A.3
  • 41
    • 0034026449 scopus 로고    scopus 로고
    • Proopiomelanocortin (POMC) products in the central regulation of sympathetic and cardiovascular dynamics; studies on melanocortin and opioid interactions
    • Dunbar JC, LU H. Proopiomelanocortin (POMC) products in the central regulation of sympathetic and cardiovascular dynamics; studies on melanocortin and opioid interactions. Peptides 2000; 21: 211-217.
    • (2000) Peptides , vol.21 , pp. 211-217
    • Dunbar, J.C.1    Lu, H.2
  • 43
    • 0036280459 scopus 로고    scopus 로고
    • Human leptin administered intraperitoneally stimulates natriurezis and decreases renal medullary Na+, K+ -ATP ase activity in the rat- Impaired effect in dietary- induced obesity
    • Beltowski J Wojcicka G, Gorny D, Marcinial A. Human leptin administered intraperitoneally stimulates natriurezis and decreases renal medullary Na+, K+ -ATP ase activity in the rat- impaired effect in dietary- induced obesity. Med Sci Monit 2002; 8(6): BR221-229.
    • (2002) Med Sci Monit , vol.8 , Issue.6
    • Beltowski, J.1    Wojcicka, G.2    Gorny, D.3    Marcinial, A.4
  • 44
  • 46
    • 0032440815 scopus 로고    scopus 로고
    • Renal effects of leptin in normotensive, hypertensive, and obese rats
    • Villerreal O, Reams G, Freeman RH, Taraben A. Renal effects of leptin in normotensive, hypertensive, and obese rats. Am J Physiol 1998; 275, R 2056-2060.
    • (1998) Am J Physiol , vol.275 , pp. 2056-2060
    • Villerreal, O.1    Reams, G.2    Freeman, R.H.3    Taraben, A.4
  • 47
    • 0036020935 scopus 로고    scopus 로고
    • Obesity - A neglected culprit in renal disease
    • Praga M. Obesity- a neglected culprit in renal disease. Nephrol Dial Transplant. 2002; 17: 1157-1159.
    • (2002) Nephrol Dial Transplant , vol.17 , pp. 1157-1159
    • Praga, M.1
  • 48
    • 0033944103 scopus 로고    scopus 로고
    • Leptin and blood pressure - Is there a link?
    • Stenvinkal P. Leptin and blood pressure-is there a link? Nephral Dial Transplant. 2000; 1: 1115-1117.
    • (2000) Nephral Dial Transplant , vol.1 , pp. 1115-1117
    • Stenvinkal, P.1
  • 49
    • 0035958957 scopus 로고    scopus 로고
    • Endothelin-1 stimulates leptin production in adipocytes
    • Xiong Y, Tanaka H, Richardson JA, Williams SC et al. Endothelin-1 stimulates leptin production in adipocytes. J. Biol chem. 2001; 276 (30): 28471-28477.
    • (2001) J. Biol Chem. , vol.276 , Issue.30 , pp. 28471-28477
    • Xiong, Y.1    Tanaka, H.2    Richardson, J.A.3    Williams, S.C.4
  • 50
    • 0036091969 scopus 로고    scopus 로고
    • Leptin effect on endothelial nitric oxide is mediated through Akt-endothelial nitric oxide synthase phoshorylation pathway
    • Vecchione C, Maffei A, Collelta S, Aretini A et al. Leptin effect on endothelial nitric oxide is mediated through Akt-endothelial nitric oxide synthase phoshorylation pathway. Diabetes 2002; 51: 168-178.
    • (2002) Diabetes , vol.51 , pp. 168-178
    • Vecchione, C.1    Maffei, A.2    Collelta, S.3    Aretini, A.4
  • 52
    • 0033047528 scopus 로고    scopus 로고
    • An independent relationship between plasma leptin and heart rate in untreated patients with essential hypertension
    • Narkiewicz K, Somers UK, Mos L, Kato M et al. An independent relationship between plasma leptin and heart rate in untreated patients with essential hypertension. J Hypertension. 1999; 17: 245-249.
    • (1999) J Hypertension , vol.17 , pp. 245-249
    • Narkiewicz, K.1    Somers, U.K.2    Mos, L.3    Kato, M.4
  • 53
    • 0033775092 scopus 로고    scopus 로고
    • Leptin attenuates cardiac contraction in rat ventricular myocytes. Role of NO
    • Nickola MW, Wold LE, Colligan PB, Wang GJ et al. Leptin attenuates cardiac contraction in rat ventricular myocytes. Role of NO. Hypertension. 2000; 36: 501-505.
    • (2000) Hypertension , vol.36 , pp. 501-505
    • Nickola, M.W.1    Wold, L.E.2    Colligan, P.B.3    Wang, G.J.4


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