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Volumn 32, Issue 7, 2004, Pages 1460-1469

Delayed neutrophil apoptosis in sepsis is associated with maintenance of mitochondrial transmembrane potential and reduced caspase-9 activity

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 9; CYTOCHROME C; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA CONVERTING ENZYME; LIPOPOLYSACCHARIDE; PYRROLIDINE DITHIOCARBAMATE;

EID: 3142704153     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000129975.26905.77     Document Type: Article
Times cited : (195)

References (73)
  • 1
    • 0033590515 scopus 로고    scopus 로고
    • Treating patients with severe sepsis
    • Wheeler AP, Bernard GR: Treating patients with severe sepsis. N Engl J Med 1999; 340:207-214
    • (1999) N Engl J Med , vol.340 , pp. 207-214
    • Wheeler, A.P.1    Bernard, G.R.2
  • 2
    • 0037426726 scopus 로고    scopus 로고
    • The pathophysiology and treatment of sepsis
    • Hotchkiss RS, Karl IE: The pathophysiology and treatment of sepsis. N Engl J Med 2003; 348:238-250
    • (2003) N Engl J Med , vol.348 , pp. 238-250
    • Hotchkiss, R.S.1    Karl, I.E.2
  • 3
    • 0026710191 scopus 로고
    • Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
    • Bone RC, Balk RA, Cerra FB, et al: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest 1992; 101:1644-1655
    • (1992) Chest , vol.101 , pp. 1644-1655
    • Bone, R.C.1    Balk, R.A.2    Cerra, F.B.3
  • 4
    • 0034958947 scopus 로고    scopus 로고
    • Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
    • Angus DC, Linde-Zwirble WT, Lidicker J, et al: Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001; 29:1303-1310
    • (2001) Crit Care Med , vol.29 , pp. 1303-1310
    • Angus, D.C.1    Linde-Zwirble, W.T.2    Lidicker, J.3
  • 5
    • 0037451929 scopus 로고    scopus 로고
    • The epidemiology of sepsis in the United States from 1979 through 2000
    • Martin GS, Mannino DM, Eaton S, et al: The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 2003; 348:1546-1554
    • (2003) N Engl J Med , vol.348 , pp. 1546-1554
    • Martin, G.S.1    Mannino, D.M.2    Eaton, S.3
  • 6
    • 0034619970 scopus 로고    scopus 로고
    • Immunodeficiency diseases caused by defects in phagocytes
    • Lekstrom-Himes JA, Gallin JI: Immunodeficiency diseases caused by defects in phagocytes. N Engl J Med 2000; 343:1703-1714
    • (2000) N Engl J Med , vol.343 , pp. 1703-1714
    • Lekstrom-Himes, J.A.1    Gallin, J.I.2
  • 7
    • 0035863363 scopus 로고    scopus 로고
    • Current status of granulocyte (neutrophil) transfusion therapy for infectious diseases
    • Hubel K, Dale DC, Engert A, et al: Current status of granulocyte (neutrophil) transfusion therapy for infectious diseases. J Infect Dis 2001; 183:321-328
    • (2001) J Infect Dis , vol.183 , pp. 321-328
    • Hubel, K.1    Dale, D.C.2    Engert, A.3
  • 8
    • 0033969341 scopus 로고    scopus 로고
    • Proversus anti-inflammatory cytokine profile in patients with severe sepsis: A marker for prognosis and future therapeutic options
    • Gogos CA, Drosou E, Bassaris HP, et al: Proversus anti-inflammatory cytokine profile in patients with severe sepsis: A marker for prognosis and future therapeutic options. J Infect Dis 2000; 181:176-180
    • (2000) J Infect Dis , vol.181 , pp. 176-180
    • Gogos, C.A.1    Drosou, E.2    Bassaris, H.P.3
  • 9
    • 0034927826 scopus 로고    scopus 로고
    • Sepsis and evolution of the innate immune response
    • Beutler B, Poltorak A: Sepsis and evolution of the innate immune response. Crit Care Med 2001; 29:S2-S7
    • (2001) Crit Care Med , vol.29
    • Beutler, B.1    Poltorak, A.2
  • 10
    • 0034780733 scopus 로고    scopus 로고
    • Heparin-binding protein (HBP/CAP37): A missing link in neutrophil-evoked alteration of vascular permeability
    • Gautam N, Olofsson AM, Herwald H, et al: Heparin-binding protein (HBP/CAP37): A missing link in neutrophil-evoked alteration of vascular permeability. Nature Med 2001; 7:1123-1127
    • (2001) Nature Med , vol.7 , pp. 1123-1127
    • Gautam, N.1    Olofsson, A.M.2    Herwald, H.3
  • 11
    • 0035674981 scopus 로고    scopus 로고
    • Apoptosis in cells of bronchoalveolar lavage: A cellular reaction in patients who die with sepsis and respiratory failure
    • Liacos C, Katsaragakis S, Konstadoulakis MM, et al: Apoptosis in cells of bronchoalveolar lavage: A cellular reaction in patients who die with sepsis and respiratory failure. Crit Care Med 2001; 29:2310-2317
    • (2001) Crit Care Med , vol.29 , pp. 2310-2317
    • Liacos, C.1    Katsaragakis, S.2    Konstadoulakis, M.M.3
  • 12
    • 0028556421 scopus 로고
    • Neutrophils, host defense, and inflammation: A double-edged sword
    • Smith JA: Neutrophils, host defense, and inflammation: A double-edged sword. J Leuk Biol 1994; 56:672-686
    • (1994) J Leuk Biol , vol.56 , pp. 672-686
    • Smith, J.A.1
  • 13
    • 0037394676 scopus 로고    scopus 로고
    • Neutrophils and acute lung injury
    • Abraham E: Neutrophils and acute lung injury. Crit Care Med 2003; 31(Suppl): S195-S199
    • (2003) Crit Care Med , vol.31 , Issue.SUPPL.
    • Abraham, E.1
  • 14
    • 0001178459 scopus 로고    scopus 로고
    • A novel mechanism for attenuating neutrophil-mediated lung injury in vivo
    • Sookhai S, Wang JH, McCourt M, et al: A novel mechanism for attenuating neutrophil-mediated lung injury in vivo. Surg Forum 1999; 50:205-208
    • (1999) Surg Forum , vol.50 , pp. 205-208
    • Sookhai, S.1    Wang, J.H.2    McCourt, M.3
  • 15
    • 0029891492 scopus 로고    scopus 로고
    • Identification of factors from rat neutrophils responsible for cytotoxicity to isolated hepatocytes
    • Ho JS, Buchweitz JP, Roth RA, et al: Identification of factors from rat neutrophils responsible for cytotoxicity to isolated hepatocytes. J Leuk Biol 1996; 59:716-724
    • (1996) J Leuk Biol , vol.59 , pp. 716-724
    • Ho, J.S.1    Buchweitz, J.P.2    Roth, R.A.3
  • 16
    • 0026782483 scopus 로고
    • Ischemia/ reperfusion induced feline intestinal dysfunction: Importance of granulocyte recruitment
    • Kubes P, Hunter J, Granger DN: Ischemia/ reperfusion induced feline intestinal dysfunction: Importance of granulocyte recruitment. Gastroenterology 1992; 103:807-812
    • (1992) Gastroenterology , vol.103 , pp. 807-812
    • Kubes, P.1    Hunter, J.2    Granger, D.N.3
  • 17
    • 0032560544 scopus 로고    scopus 로고
    • Resistance to endotoxic shock and reduced neutrophil migration in mice deficient for the Src-family kinases Hck and Fgr
    • Lowell CA, Berton G: Resistance to endotoxic shock and reduced neutrophil migration in mice deficient for the Src-family kinases Hck and Fgr. Proc Natl Acad Sci U S A 1998; 95:7580-7584
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 7580-7584
    • Lowell, C.A.1    Berton, G.2
  • 18
    • 0028243988 scopus 로고
    • Evolution of bronchoalveolar cell populations in the adult respiratory distress syndrome
    • Steinberg KP, Milberg JA, Martin TR, et al: Evolution of bronchoalveolar cell populations in the adult respiratory distress syndrome. Am J Respir Crit Care Med 1994; 150:113-122
    • (1994) Am J Respir Crit Care Med , vol.150 , pp. 113-122
    • Steinberg, K.P.1    Milberg, J.A.2    Martin, T.R.3
  • 19
    • 0022364739 scopus 로고
    • Multiple organ failure. Generalized autodestructive inflammation?
    • Goris RJA, te Boekhorst TPA, Nuytinck JKS, et al: Multiple organ failure. Generalized autodestructive inflammation? Arch Surg 1985; 120:1109-1115
    • (1985) Arch Surg , vol.120 , pp. 1109-1115
    • Goris, R.J.A.1    Te Boekhorst, T.P.A.2    Nuytinck, J.K.S.3
  • 20
    • 0031004487 scopus 로고    scopus 로고
    • Apoptosis in resolution of inflammation
    • Savill J: Apoptosis in resolution of inflammation. J Leuk Biol 1997; 61:375-380
    • (1997) J Leuk Biol , vol.61 , pp. 375-380
    • Savill, J.1
  • 21
    • 0026465484 scopus 로고
    • Resolution of acute inflammation and the role of apoptosis in the tissue fate of granulocytes
    • Haslett C: Resolution of acute inflammation and the role of apoptosis in the tissue fate of granulocytes. Clin Sci 1992; 83:639-648
    • (1992) Clin Sci , vol.83 , pp. 639-648
    • Haslett, C.1
  • 22
    • 0037442128 scopus 로고    scopus 로고
    • The mitochondrial network of human neutrophils: Role in chemotaxis, phagocytosis, respiratory burst activation, and commitment to apoptosis
    • Fossati G, Moulding DA, Spiller DG, et al: The mitochondrial network of human neutrophils: Role in chemotaxis, phagocytosis, respiratory burst activation, and commitment to apoptosis. J Immunol 2003; 170: 1972
    • (2003) J Immunol , vol.170 , pp. 1972
    • Fossati, G.1    Moulding, D.A.2    Spiller, D.G.3
  • 23
    • 0742306781 scopus 로고    scopus 로고
    • Functional characterization of mitochondria in neutrophils: A role restricted to apoptosis
    • Epub ahead of print
    • Maianski NA, Geissler J, Srinivasula SM, et al: Functional characterization of mitochondria in neutrophils: A role restricted to apoptosis. Cell Death Differ 2004 [Epub ahead of print]
    • (2004) Cell Death Differ
    • Maianski, N.A.1    Geissler, J.2    Srinivasula, S.M.3
  • 24
    • 0346727505 scopus 로고    scopus 로고
    • Suppression of mitochondria-dependent neutrophil apoptosis with thermal injury
    • Hu Z, Sayeed MM: Suppression of mitochondria-dependent neutrophil apoptosis with thermal injury. Am J Physiol Cell Physiol 2004; 286:C170-C178
    • (2004) Am J Physiol Cell Physiol , vol.286
    • Hu, Z.1    Sayeed, M.M.2
  • 25
    • 0029960839 scopus 로고    scopus 로고
    • Neutrophils undergo apoptosis following ingestion of Escherichia coli
    • Watson RWG, Redmond HP, Wang JH, et al: Neutrophils undergo apoptosis following ingestion of Escherichia coli. J Immunol 1996; 156:3986-3992
    • (1996) J Immunol , vol.156 , pp. 3986-3992
    • Watson, R.W.G.1    Redmond, H.P.2    Wang, J.H.3
  • 26
    • 0034278285 scopus 로고    scopus 로고
    • Phagocytosis of Candida albicans induces apoptosis of human neutrophils
    • Rotstein D, Parodo J, Taneja R, et al: Phagocytosis of Candida albicans induces apoptosis of human neutrophils. Shock 2000; 14: 278-283
    • (2000) Shock , vol.14 , pp. 278-283
    • Rotstein, D.1    Parodo, J.2    Taneja, R.3
  • 27
    • 0027484754 scopus 로고
    • Inhibition of apoptosis and prolongation of neutrophil functional longevity by inflammatory mediators
    • Lee A, Whyte MKB, Haslett C: Inhibition of apoptosis and prolongation of neutrophil functional longevity by inflammatory mediators. J Leuk Biol 1993; 54:283-288
    • (1993) J Leuk Biol , vol.54 , pp. 283-288
    • Lee, A.1    Whyte, M.K.B.2    Haslett, C.3
  • 28
    • 0030927658 scopus 로고    scopus 로고
    • Programmed cell death (apoptosis) and the resolution of systemic inflammation
    • Marshall JC, Watson RWG: Programmed cell death (apoptosis) and the resolution of systemic inflammation. Can J Surg 1997; 40: 169-174
    • (1997) Can J Surg , vol.40 , pp. 169-174
    • Marshall, J.C.1    Watson, R.W.G.2
  • 29
    • 0032528510 scopus 로고    scopus 로고
    • The interleukin-1 beta converting enzyme (caspase-1) inhibits apoptosis of inflammatory neutrophils through activation of IL-1b
    • Watson RWG, Rotstein OD, Parodo J, et al: The interleukin-1 beta converting enzyme (caspase-1) inhibits apoptosis of inflammatory neutrophils through activation of IL-1b. J Immunol 1998; 161:957-962
    • (1998) J Immunol , vol.161 , pp. 957-962
    • Watson, R.W.G.1    Rotstein, O.D.2    Parodo, J.3
  • 30
    • 2642603194 scopus 로고    scopus 로고
    • Dysregulated expression of neutrophil apoptosis in the systemic inflammatory response syndrome (SIRS)
    • Jimenez MF, Watson RWG, Parodo J, et al: Dysregulated expression of neutrophil apoptosis in the systemic inflammatory response syndrome (SIRS). Arch Surg 1997; 132: 1263-1270
    • (1997) Arch Surg , vol.132 , pp. 1263-1270
    • Jimenez, M.F.1    Watson, R.W.G.2    Parodo, J.3
  • 31
    • 0030736624 scopus 로고    scopus 로고
    • Interleukin-10 counterregulates proinflammatory cytokine-induced inhibition of neutrophil apoptosis during severe sepsis
    • Keel M, Ungethum U, Steckholzer U, et al: Interleukin-10 counterregulates proinflammatory cytokine-induced inhibition of neutrophil apoptosis during severe sepsis. Blood 1997; 90:3356-3363
    • (1997) Blood , vol.90 , pp. 3356-3363
    • Keel, M.1    Ungethum, U.2    Steckholzer, U.3
  • 32
    • 0029892542 scopus 로고    scopus 로고
    • Inhibition of apoptosis in polymorphonuclear neutrophils from burn patients
    • Chitnis D, Dickerson C, Munster AM, et al: Inhibition of apoptosis in polymorphonuclear neutrophils from burn patients. J Leukocyte Biol 1996; 59:835-839
    • (1996) J Leukocyte Biol , vol.59 , pp. 835-839
    • Chitnis, D.1    Dickerson, C.2    Munster, A.M.3
  • 33
    • 0031777879 scopus 로고    scopus 로고
    • Circulating mediators in serum of injured patients with septic complications inhibit neutrophil apoptosis through up-regulation of protein-tyrosine phosphorylation
    • Ertel W, Keel M, Infanger M, et al: Circulating mediators in serum of injured patients with septic complications inhibit neutrophil apoptosis through up-regulation of protein-tyrosine phosphorylation. J Trauma 1998; 44:767-775
    • (1998) J Trauma , vol.44 , pp. 767-775
    • Ertel, W.1    Keel, M.2    Infanger, M.3
  • 34
    • 0031464308 scopus 로고    scopus 로고
    • Neutrophil apoptosis in acute respiratory distress syndrome
    • Matute-Bello G, Liles WC: Neutrophil apoptosis in acute respiratory distress syndrome. Am Rev Respir Crit Care Med 1997; 156: 1969-1977
    • (1997) Am Rev Respir Crit Care Med , vol.156 , pp. 1969-1977
    • Matute-Bello, G.1    Liles, W.C.2
  • 35
    • 0038482456 scopus 로고    scopus 로고
    • Such stuff as dreams are made on: Mediator-targeted therapy in sepsis
    • Marshall JC: Such stuff as dreams are made on: Mediator-targeted therapy in sepsis. Nature Rev Drug Disc 2003; 2:391-405
    • (2003) Nature Rev Drug Disc , vol.2 , pp. 391-405
    • Marshall, J.C.1
  • 36
    • 0022256529 scopus 로고
    • APACHE II: A severity of disease classification system
    • Knaus WA, Draper EA, Wagner DP, et al: APACHE II: A severity of disease classification system. Crit Care Med 1985; 13: 818-829
    • (1985) Crit Care Med , vol.13 , pp. 818-829
    • Knaus, W.A.1    Draper, E.A.2    Wagner, D.P.3
  • 37
    • 0028784689 scopus 로고
    • Multiple organ dysfunction score: A reliable descriptor of a complex clinical outcome
    • Marshall JC, Cook DJ, Christou NV, et al: Multiple organ dysfunction score: A reliable descriptor of a complex clinical outcome. Crit Care Med 1995; 23:1638-1652
    • (1995) Crit Care Med , vol.23 , pp. 1638-1652
    • Marshall, J.C.1    Cook, D.J.2    Christou, N.V.3
  • 38
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti I, Migliorati G, Pagliacci MC, et al: A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 1991; 139:271-276
    • (1991) J Immunol Methods , vol.139 , pp. 271-276
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3
  • 39
    • 0029803263 scopus 로고    scopus 로고
    • Thiol-mediated redox regulation of neutrophil apoptosis
    • Watson RWG, Rotstein OD, Nathens AB, et al: Thiol-mediated redox regulation of neutrophil apoptosis. Surgery 1996; 120: 150-158
    • (1996) Surgery , vol.120 , pp. 150-158
    • Watson, R.W.G.1    Rotstein, O.D.2    Nathens, A.B.3
  • 40
    • 0003083966 scopus 로고
    • Isolation of liver or kidney mitochondria
    • Estabrook RW, Pullman ME (Eds). New York, Academic Press
    • Johnson D, Lardy H. Isolation of liver or kidney mitochondria. In: Methods in Enzymology, Volume 10. Estabrook RW, Pullman ME (Eds). New York, Academic Press, 1967, pp 86-93
    • (1967) Methods in Enzymology , vol.10 , pp. 86-93
    • Johnson, D.1    Lardy, H.2
  • 41
    • 0000402167 scopus 로고
    • Oxidation of fatty acid and tricarboxylic acid cycle intermediates by isolated rat liver mitochondria
    • Kennedy EP, Lehninger AL: Oxidation of fatty acid and tricarboxylic acid cycle intermediates by isolated rat liver mitochondria. J Biol Chem 1949; 179:957-972
    • (1949) J Biol Chem , vol.179 , pp. 957-972
    • Kennedy, E.P.1    Lehninger, A.L.2
  • 42
    • 0029163601 scopus 로고
    • Retrovirus-mediated transfer of nuclear factor-kB subunit genes modulates IkBa and interferon b expression
    • Bitar R, Beauparlant P, Lin R, et al: Retrovirus-mediated transfer of nuclear factor-kB subunit genes modulates IkBa and interferon b expression. Cell Growth Differ 1995; 6:965-976
    • (1995) Cell Growth Differ , vol.6 , pp. 965-976
    • Bitar, R.1    Beauparlant, P.2    Lin, R.3
  • 43
    • 0033775615 scopus 로고    scopus 로고
    • Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays
    • Bustin SA: Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays. J Molec Endocrinol 2000; 25:169-193
    • (2000) J Molec Endocrinol , vol.25 , pp. 169-193
    • Bustin, S.A.1
  • 44
    • 0034651781 scopus 로고    scopus 로고
    • Quantitation of dihydropyrimidine dehydrogenase expression by real-time reverse transcription polymerase chain reaction
    • Johnson MR, Wang K, Smith JB, et al: Quantitation of dihydropyrimidine dehydrogenase expression by real-time reverse transcription polymerase chain reaction. Anal Biochem 2000; 278:175-184
    • (2000) Anal Biochem , vol.278 , pp. 175-184
    • Johnson, M.R.1    Wang, K.2    Smith, J.B.3
  • 45
    • 0345961953 scopus 로고    scopus 로고
    • Dysregulated neutrophil apoptosis in the pathogenesis of organ injury in critical illness
    • Fink MP, Evans TW (Eds). Berlin, Springer-Verlag
    • Marshall JC, Jia S-H, Taneja R: Dysregulated neutrophil apoptosis in the pathogenesis of organ injury in critical illness. In: Mechanisms of Organ Dysfunction in Critical Illness. Fink MP, Evans TW (Eds). Berlin, Springer-Verlag, 2002, pp 110-123
    • (2002) Mechanisms of Organ Dysfunction in Critical Illness , pp. 110-123
    • Marshall, J.C.1    Jia, S.-H.2    Taneja, R.3
  • 46
    • 0029976817 scopus 로고    scopus 로고
    • An essential role for NF-kappaB in preventing TNF-α-induced cell death
    • Beg AA, Baltimore D: An essential role for NF-kappaB in preventing TNF-α-induced cell death. Science 1996; 274:782-784
    • (1996) Science , vol.274 , pp. 782-784
    • Beg, A.A.1    Baltimore, D.2
  • 47
    • 0029992609 scopus 로고    scopus 로고
    • Suppression of TNF-α-induced apoptosis by NF-kappaB
    • Van Antwerp DJ, Martin SJ, Kafri T, et al: Suppression of TNF-α-induced apoptosis by NF-kappaB. Science 1996; 274:787-789
    • (1996) Science , vol.274 , pp. 787-789
    • Van Antwerp, D.J.1    Martin, S.J.2    Kafri, T.3
  • 48
    • 0030610685 scopus 로고    scopus 로고
    • Activation of the NF-kB pathway by inflammatory stimuli in human neutrophils
    • McDonald PP, Bald A, Cassatella MA: Activation of the NF-kB pathway by inflammatory stimuli in human neutrophils. Blood 1997; 89:3421-3433
    • (1997) Blood , vol.89 , pp. 3421-3433
    • McDonald, P.P.1    Bald, A.2    Cassatella, M.A.3
  • 49
    • 0032575750 scopus 로고    scopus 로고
    • Caspases: Enemies within
    • Thornberry NA, Lazebnik YA: Caspases: Enemies within. Science 1998; 281:1312-1316
    • (1998) Science , vol.281 , pp. 1312-1316
    • Thornberry, N.A.1    Lazebnik, Y.A.2
  • 50
    • 0006960225 scopus 로고    scopus 로고
    • A duel to the death: Activated caspases meet their substrates
    • Slee EA, Harte MT, Martin SJ: A duel to the death: Activated caspases meet their substrates. Sepsis 1998; 2:21-29
    • (1998) Sepsis , vol.2 , pp. 21-29
    • Slee, E.A.1    Harte, M.T.2    Martin, S.J.3
  • 51
    • 0033121315 scopus 로고    scopus 로고
    • Bcl-Xl and Bax-a-mediated regulation of apoptosis of human neutrophils via caspase-3
    • Weinmann P, Gaehtgens P, Walzog B: Bcl-Xl and Bax-a-mediated regulation of apoptosis of human neutrophils via caspase-3. Blood 1999; 93:3106-3115
    • (1999) Blood , vol.93 , pp. 3106-3115
    • Weinmann, P.1    Gaehtgens, P.2    Walzog, B.3
  • 52
    • 0029026548 scopus 로고
    • FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
    • Chinnaiyan AM, O'Rourke K, Tewari M, et al: FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 1995; 81: 505-512
    • (1995) Cell , vol.81 , pp. 505-512
    • Chinnaiyan, A.M.1    O'Rourke, K.2    Tewari, M.3
  • 53
    • 0033579810 scopus 로고    scopus 로고
    • Mitochondrial release of caspase-2 and -9 during the apoptotic process
    • Susin SA, Lorenzo HK, Zamzami N, et al: Mitochondrial release of caspase-2 and -9 during the apoptotic process. J Exp Med 1999; 189:381-393
    • (1999) J Exp Med , vol.189 , pp. 381-393
    • Susin, S.A.1    Lorenzo, H.K.2    Zamzami, N.3
  • 54
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li P, Nijhawan D, Budihardjo I, et al: Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997; 91:479-489
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3
  • 55
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green DR, Reed JC: Mitochondria and apoptosis. Science 1998; 281:1309-1312
    • (1998) Science , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 56
    • 0029821989 scopus 로고    scopus 로고
    • Interactions between neutrophils and cytokines in blood and alveolar spaces during ARDS
    • Chollet-Martin S, Jourdain B, Gibert C, et al: Interactions between neutrophils and cytokines in blood and alveolar spaces during ARDS. Am J Respir Crit Care Med 1996; 154:594-601
    • (1996) Am J Respir Crit Care Med , vol.154 , pp. 594-601
    • Chollet-Martin, S.1    Jourdain, B.2    Gibert, C.3
  • 57
    • 0026650148 scopus 로고
    • Elevated levels of NAP-1/interleukin-8 are present in the airspaces of patients with the adult respiratory distress syndrome and are associated with increased mortality
    • Miller EJ, Cohen AB, Nagao S, et al: Elevated levels of NAP-1/interleukin-8 are present in the airspaces of patients with the adult respiratory distress syndrome and are associated with increased mortality. Am Rev Respir Dis 1992; 146:427-432
    • (1992) Am Rev Respir Dis , vol.146 , pp. 427-432
    • Miller, E.J.1    Cohen, A.B.2    Nagao, S.3
  • 58
    • 0019846903 scopus 로고
    • Prevention by granulocyte depletion of increased vascular permeability of sheep lung following endotoxemia
    • Heflin AC, Brigham KL: Prevention by granulocyte depletion of increased vascular permeability of sheep lung following endotoxemia. J Clin Invest 1981; 68:1253-1260
    • (1981) J Clin Invest , vol.68 , pp. 1253-1260
    • Heflin, A.C.1    Brigham, K.L.2
  • 59
    • 0031278622 scopus 로고    scopus 로고
    • Pyrrolidine dithiocarbamate attenuates endotoxin-induced lung injury
    • Nathens AB, Bitar R, Bujard M, et al: Pyrrolidine dithiocarbamate attenuates endotoxin-induced lung injury. Am J Respir Cell Mol Biol 1997; 17:608-616
    • (1997) Am J Respir Cell Mol Biol , vol.17 , pp. 608-616
    • Nathens, A.B.1    Bitar, R.2    Bujard, M.3
  • 60
    • 0032519925 scopus 로고    scopus 로고
    • Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGFb, PGE2, and PAF
    • Fadok VA, Bratton DL, Konowal A, et al: Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGFb, PGE2, and PAF. J Clin Invest 1998; 101:890-898
    • (1998) J Clin Invest , vol.101 , pp. 890-898
    • Fadok, V.A.1    Bratton, D.L.2    Konowal, A.3
  • 61
    • 0031812799 scopus 로고    scopus 로고
    • Regulation of granulocyte apoptosis and implications for anti-inflammatory therapy
    • Chilvers ER, Rossi AG, Murray J, et al: Regulation of granulocyte apoptosis and implications for anti-inflammatory therapy. Thorax 1998; 53:533-534
    • (1998) Thorax , vol.53 , pp. 533-534
    • Chilvers, E.R.1    Rossi, A.G.2    Murray, J.3
  • 62
    • 0034641932 scopus 로고    scopus 로고
    • From bench to clinic with apoptosis-based therapeutic agents
    • Nicholson DW: From bench to clinic with apoptosis-based therapeutic agents. Nature 2000; 407:810-816
    • (2000) Nature , vol.407 , pp. 810-816
    • Nicholson, D.W.1
  • 63
    • 0034655090 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor delays neutrophil constitutive apoptosis through phosphoinositide 3-kinase and extracellular signal-regulated kinase pathways
    • Renshaw SA, Timmons SJ, Eaton V, et al: Granulocyte-macrophage colony-stimulating factor delays neutrophil constitutive apoptosis through phosphoinositide 3-kinase and extracellular signal-regulated kinase pathways. J Immunol 2000; 164:4286-4291
    • (2000) J Immunol , vol.164 , pp. 4286-4291
    • Renshaw, S.A.1    Timmons, S.J.2    Eaton, V.3
  • 64
    • 0033539507 scopus 로고    scopus 로고
    • Cytokine-mediated Bax deficiency and consequent delayed neutrophil apoptosis: A general mechanism to accumulate effector cells in inflammation
    • Dibbert B, Weber M, Nikolaizik WH, et al: Cytokine-mediated Bax deficiency and consequent delayed neutrophil apoptosis: A general mechanism to accumulate effector cells in inflammation. Proc Natl Acad Sci U S A 1999; 23:13335
    • (1999) Proc Natl Acad Sci U S A , vol.23 , pp. 13335
    • Dibbert, B.1    Weber, M.2    Nikolaizik, W.H.3
  • 65
    • 0031743756 scopus 로고    scopus 로고
    • Accelerated neutrophil apoptosis in mice lacking A1-a, a subtype of the bcl-2-related gene
    • Hamasaki A, Sendo F, Nakayama K, et al: Accelerated neutrophil apoptosis in mice lacking A1-a, a subtype of the bcl-2-related gene. J Exp Med 1998; 188:1985-1992
    • (1998) J Exp Med , vol.188 , pp. 1985-1992
    • Hamasaki, A.1    Sendo, F.2    Nakayama, K.3
  • 66
    • 0032189802 scopus 로고    scopus 로고
    • Mcl-1 expression in human neutrophils: Regulation by cytokines and correlation with cell survival
    • Moulding DA, Quayle JA, Hart CA, et al: Mcl-1 expression in human neutrophils: Regulation by cytokines and correlation with cell survival. Blood 1998; 92:2495-2502
    • (1998) Blood , vol.92 , pp. 2495-2502
    • Moulding, D.A.1    Quayle, J.A.2    Hart, C.A.3
  • 67
    • 0028927484 scopus 로고
    • Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix
    • Boudreau N, Sympson CJ, Werb Z, et al: Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix. Science 1995; 267:891-893
    • (1995) Science , vol.267 , pp. 891-893
    • Boudreau, N.1    Sympson, C.J.2    Werb, Z.3
  • 68
    • 0002700808 scopus 로고    scopus 로고
    • The mitochondrial permeability transition: Role in ischemia/reperfusion injury
    • Halestrap A, Kerr PM, Javadov S, et al: The mitochondrial permeability transition: Role in ischemia/reperfusion injury. Sepsis 1998; 2:313-325
    • (1998) Sepsis , vol.2 , pp. 313-325
    • Halestrap, A.1    Kerr, P.M.2    Javadov, S.3
  • 69
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
    • Kluck RM, Bossy-Wetzel E, Green DR, et al: The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis. Science 1997; 275:1132-1136
    • (1997) Science , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3
  • 70
    • 0035422607 scopus 로고    scopus 로고
    • Mitochondrial membrane potential and apoptosis in peripheral blood monocytes in severe human sepsis
    • Adrie C, Bachelet M, Vayssier-Taussat M, et al: Mitochondrial membrane potential and apoptosis in peripheral blood monocytes in severe human sepsis. Am J Respir Crit Care Med 2001; 164:389-395
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 389-395
    • Adrie, C.1    Bachelet, M.2    Vayssier-Taussat, M.3
  • 71
    • 0029858387 scopus 로고    scopus 로고
    • TNF-and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kappaB
    • Wang CY, Mayo MW, Baldwin AS Jr: TNF-and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kappaB. Science 1996; 274:784-787
    • (1996) Science , vol.274 , pp. 784-787
    • Wang, C.Y.1    Mayo, M.W.2    Baldwin Jr., A.S.3
  • 72
    • 0030611086 scopus 로고    scopus 로고
    • The role of NFkB in the mortality of sepsis
    • Böhrer H, Qiu F, Zimmermann T, et al: The role of NFkB in the mortality of sepsis. J Clin Invest 1997; 100:972-985
    • (1997) J Clin Invest , vol.100 , pp. 972-985
    • Böhrer, H.1    Qiu, F.2    Zimmermann, T.3
  • 73
    • 0034746919 scopus 로고    scopus 로고
    • NF-kB: A key role in inflammatory diseases
    • Tak PP, Firestein GS: NF-kB: A key role in inflammatory diseases. J Clin Invest 2001; 107:7-11
    • (2001) J Clin Invest , vol.107 , pp. 7-11
    • Tak, P.P.1    Firestein, G.S.2


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