Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesis

Development

Volumn 131, Issue 14, 2004, Pages 3401-3410

  Michos, Odyssé ^a,b   Panman, Lia ^b   Vintersten, Kristina ^c,e   Beier, Konstantin ^d   Zeller, Rolf ^a   Zuniga, Aimée ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b UTRECHT UNIVERSITY   (Netherlands)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^d UNIVERSITY OF BASEL   (Switzerland)

^e MOUNT SINAI HOSPITAL   (Canada)

Author keywords

BMP antagonism; Grem1; Gremlin; Kidney; Limb bud; Mouse; Organogenesis

Indexed keywords

BONE MORPHOGENETIC PROTEIN; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; MORPHOGEN; PROTEIN GREM1; PROTEIN RET; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG; CKTSF1B1 PROTEIN, MOUSE; SIGNAL PEPTIDE; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ECTODERM; EMBRYO; EPITHELIUM CELL; FEEDBACK SYSTEM; GENE DISRUPTION; GENE INTERACTION; GENE MUTATION; GENE TARGETING; GENETIC REGULATION; GENETIC VARIABILITY; KIDNEY AGENESIS; KIDNEY DEVELOPMENT; KIDNEY EPITHELIUM; KIDNEY INTERSTITIUM; LIMB BUD; LIMB DEVELOPMENT; LUNG MALFORMATION; MESENCHYME CELL; MOUSE; NEWBORN; NONHUMAN; NULL ALLELE; PRIORITY JOURNAL; PROTEIN FAMILY; SIGNAL TRANSDUCTION; TERATOGENICITY; URETER; ALLELE; ANIMAL; BIOLOGICAL MODEL; EPITHELIUM; KIDNEY; LIMB; LUNG; MESODERM; METABOLISM; MUTATION; NICK END LABELING; OPEN READING FRAME; PHYSIOLOGY; PRENATAL DEVELOPMENT; TIME;

ANIMALIA; ERINACEIDAE; MAMMALIA;

ALLELES; ANIMALS; ANIMALS, NEWBORN; BONE MORPHOGENETIC PROTEINS; EPITHELIUM; EXTREMITIES; FEEDBACK, BIOCHEMICAL; HEDGEHOG PROTEINS; IN SITU NICK-END LABELING; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KIDNEY; LUNG; MESODERM; MICE; MODELS, GENETIC; MUTATION; OPEN READING FRAMES; SIGNAL TRANSDUCTION; TIME FACTORS; TRANS-ACTIVATORS;

EID: 4243180526     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.01251     Document Type: Article

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