The selective glucocorticoid receptor antagonist ORG 34116 decreases immobility time in the forced swim test and affects cAMP-responsive element-binding protein phosphorylation in rat brain

Neuroendocrinology

Volumn 81, Issue 2, 2005, Pages 129-136

  Bachmann, Cornelius G ^a,b,c   Bilang Bleuel, Alicia ^a   De Carli, Sonja ^a   Linthorst, Astrid C E ^a,d   Reul, Johannes M H M ^a,d  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^d UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Adrenal steroid receptors; cAMP responsive element binding protein; Dentate gyrus; Neocortex; Stress

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLUCOCORTICOID RECEPTOR ANTAGONIST; ORG 34116; UNCLASSIFIED DRUG; CARRIER PROTEIN; ORG-34116;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; BRAIN; CONTROLLED STUDY; DENTATE GYRUS; FORCED SWIMMING TEST; IMMOBILIZATION; LONG TERM CARE; MALE; MOLECULAR MECHANICS; NEOCORTEX; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; STATISTICAL SIGNIFICANCE; ANALYSIS OF VARIANCE; ANIMAL; ANIMAL BEHAVIOR; CATALEPSY; CELL COUNT; COMPARATIVE STUDY; CYTOLOGY; DRUG EFFECT; IMMUNOHISTOCHEMISTRY; MENTAL STRESS; METABOLISM; METHODOLOGY; NERVE CELL; ORAL DRUG ADMINISTRATION; PATHOPHYSIOLOGY; PHOSPHORYLATION; REACTION TIME; SWIMMING; TIME; WISTAR RAT;

ADMINISTRATION, ORAL; ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; BRAIN; CARRIER PROTEINS; CELL COUNT; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; FREEZING REACTION, CATALEPTIC; IMMUNOHISTOCHEMISTRY; MALE; NEURONS; PHOSPHORYLATION; RATS; RATS, WISTAR; REACTION TIME; STRESS, PSYCHOLOGICAL; SWIMMING; TIME FACTORS;

EID: 23844458961     PISSN: 00283835     EISSN: None     Source Type: Journal    
DOI: 10.1159/000086413     Document Type: Article

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