메뉴 건너뛰기




Volumn 12, Issue 6, 2005, Pages 975-984

Glutamatergic hypothesis of schizophrenia: Involvement of Na +/K+-dependent glutamate transport

Author keywords

Clozapine; EAAT; GLAST; GLT; Glutamatergic synapses; Na+,K + ATPase; Neuroleptics; Prefrontal cortex; Psychosis; Synaptic excitation

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CLOZAPINE; GLUTAMATE TRANSPORTER; GLUTAMIC ACID;

EID: 30544447178     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1007/s11373-005-9015-0     Document Type: Article
Times cited : (26)

References (101)
  • 2
    • 0038469628 scopus 로고    scopus 로고
    • Transfer of glutamine between astrocytes and neurons
    • Broer S. and Brooks N., Transfer of glutamine between astrocytes and neurons. J. Neurochem. 77: 705-719, 2001.
    • (2001) J. Neurochem. , vol.77 , pp. 705-719
    • Broer, S.1    Brooks, N.2
  • 3
    • 0036829063 scopus 로고    scopus 로고
    • Glutamate uptake in synaptic plasticity: From mollusc to mammal
    • Levenson J.M., Weeber E.J., Sweatt J.D. and Eskin A., Glutamate uptake in synaptic plasticity: from mollusc to mammal. Curr. Mol. Med. 2: 593-603, 2002.
    • (2002) Curr. Mol. Med. , vol.2 , pp. 593-603
    • Levenson, J.M.1    Weeber, E.J.2    Sweatt, J.D.3    Eskin, A.4
  • 4
    • 30544436689 scopus 로고    scopus 로고
    • Inactivation of the glycine transporter I gene discloses vital role of glial glycine uptake in glycinergic inhibition
    • Gomeza J., Hülsmann S., Ohno K., Eulenberg V. Szöke K., Richter D. and Betz H., Inactivation of the glycine transporter I gene discloses vital role of glial glycine uptake in glycinergic inhibition. Neuron 40: 789-786, 2003.
    • (2003) Neuron , vol.40 , pp. 789-1786
    • Gomeza, J.1    Hülsmann, S.2    Ohno, K.3    Eulenberg, V.4    Szöke, K.5    Richter, D.6    Betz, H.7
  • 5
    • 0141676728 scopus 로고    scopus 로고
    • Dynamic equilibrium of neurotransmitter transport: Not just for reuptake anymore
    • Richerson G.B. and Wu Y., Dynamic equilibrium of neurotransmitter transport: not just for reuptake anymore. J. Neurophysiol. 90: 1363-1374, 2003.
    • (2003) J. Neurophysiol. , vol.90 , pp. 1363-1374
    • Richerson, G.B.1    Wu, Y.2
  • 6
    • 0037256290 scopus 로고    scopus 로고
    • Membrane glycine transport proteins
    • Tunnicliff G., Membrane glycine transport proteins. J. Biomed. Sci. 10: 30-36, 2003.
    • (2003) J. Biomed. Sci. , vol.10 , pp. 30-36
    • Tunnicliff, G.1
  • 7
    • 4344621634 scopus 로고    scopus 로고
    • Role of glial amino acid transporters in synaptic transmission and brain energetics
    • Marcaggi P. and Attwell D., Role of glial amino acid transporters in synaptic transmission and brain energetics. Glia 47: 217-225, 2004.
    • (2004) Glia , vol.47 , pp. 217-225
    • Marcaggi, P.1    Attwell, D.2
  • 8
    • 3042649213 scopus 로고    scopus 로고
    • GABA transporters in the mammalian cerebral cortex: Localization, development and pathological implications
    • Conti F., Minelli A. and Melone A., GABA transporters in the mammalian cerebral cortex: localization, development and pathological implications. Brain Res. Rev. 45: 196-212, 2004.
    • (2004) Brain Res. Rev. , vol.45 , pp. 196-212
    • Conti, F.1    Minelli, A.2    Melone, A.3
  • 9
    • 17744363326 scopus 로고    scopus 로고
    • Electrogenic glutamate transporters in the CNS: Molecular mechanisms, pre-steady state kinetics and their impact on synaptic signaling
    • Grewer C. and Rauen T., Electrogenic glutamate transporters in the CNS: Molecular mechanisms, pre-steady state kinetics and their impact on synaptic signaling. J. Memb. Biol. 203: 1-20, 2005.
    • (2005) J. Memb. Biol. , vol.203 , pp. 1-20
    • Grewer, C.1    Rauen, T.2
  • 10
    • 0242544067 scopus 로고    scopus 로고
    • Deletion of the mouse glycine transporter 2 results in a hyperekplexia phenotype and postnatal lethality
    • Gomeza J., Ohno K., Hülsmann S., Armsen W., Eulenberg V., Richter D.W., Laube B. and Betz H., Deletion of the mouse glycine transporter 2 results in a hyperekplexia phenotype and postnatal lethality. Neuron 40: 797-806, 2003.
    • (2003) Neuron , vol.40 , pp. 797-806
    • Gomeza, J.1    Ohno, K.2    Hülsmann, S.3    Armsen, W.4    Eulenberg, V.5    Richter, D.W.6    Laube, B.7    Betz, H.8
  • 11
    • 1842524064 scopus 로고    scopus 로고
    • Glutamate transporters: Animal models to neurologic disease
    • Maragakis N.J. and Rothstein J.D., Glutamate transporters: animal models to neurologic disease. Neurobiol. Disease 15: 461-473, 2004.
    • (2004) Neurobiol. Disease , vol.15 , pp. 461-473
    • Maragakis, N.J.1    Rothstein, J.D.2
  • 12
    • 0029777313 scopus 로고    scopus 로고
    • The dawn of excitatory amino acid research in Japan
    • Takagaki G., The dawn of excitatory amino acid research in Japan. Neurochem. Int. 29: 225-229, 1996The pioneering work by Professor Takashi Hayashi.
    • (1996) Neurochem. Int. , vol.29 , pp. 225-229
    • Takagaki, G.1
  • 13
    • 0032780415 scopus 로고    scopus 로고
    • Forty years of amino acid transmission in brain
    • Bennett M.R. and Balcar V.J., Forty years of amino acid transmission in brain. Neurochem. Int. 35: 269-280, 1999.
    • (1999) Neurochem. Int. , vol.35 , pp. 269-280
    • Bennett, M.R.1    Balcar, V.J.2
  • 14
    • 0015426691 scopus 로고
    • The structural specificity of the high affinity uptake of L-glutamate and L-aspartate by rat brain slices
    • Balcar V.J. and Johnston G.A.R., The structural specificity of the high affinity uptake of L-glutamate and L-aspartate by rat brain slices. J. Neurochem. 19: 2657-2666, 1972.
    • (1972) J. Neurochem. , vol.19 , pp. 2657-2666
    • Balcar, V.J.1    Johnston, G.A.R.2
  • 15
    • 0028535464 scopus 로고
    • Special transport and neurological significance of two amino acids in a configuration conventionally designed as D
    • Christensen H.N., Greene A.A., Kakuda D.K. and MacLeod CL., Special transport and neurological significance of two amino acids in a configuration conventionally designed as D. J. Exp. Biol. 196: 297-305, 1994.
    • (1994) J. Exp. Biol. , vol.196 , pp. 297-305
    • Christensen, H.N.1    Greene, A.A.2    Kakuda, D.K.3    MacLeod, C.L.4
  • 16
    • 0026705561 scopus 로고
    • Heterogeneity of high affinity uptake of L-glutamate and L-aspartate in the mammalian central nervous system
    • Balcar V.J. and Li Y., Heterogeneity of high affinity uptake of L-glutamate and L-aspartate in the mammalian central nervous system. Life. Sci. 51: 1467-1487, 1992.
    • (1992) Life. Sci. , vol.51 , pp. 1467-1487
    • Balcar, V.J.1    Li, Y.2
  • 17
    • 0035542464 scopus 로고    scopus 로고
    • Neurochemistry of L-glutamate transport in the CNS: Thirty years of progress
    • Balcar V.J., Takamoto A. and Yoneda Y., Neurochemistry of L-glutamate transport in the CNS: Thirty years of progress. Coll. Czech Chem. Comm. 66: 1315-1340, 2001.
    • (2001) Coll. Czech Chem. Comm. , vol.66 , pp. 1315-1340
    • Balcar, V.J.1    Takamoto, A.2    Yoneda, Y.3
  • 18
    • 0035001341 scopus 로고    scopus 로고
    • Glutamate uptake
    • Danbolt N.C., Glutamate uptake. Prog. Neurobiol. 65: 1-105, 2001.
    • (2001) Prog. Neurobiol. , vol.65 , pp. 1-105
    • Danbolt, N.C.1
  • 19
    • 0036516328 scopus 로고    scopus 로고
    • +-dependent transport of acidic amino acids in the mammalian central nervous system
    • +-dependent transport of acidic amino acids in the mammalian central nervous system. Biol. Pharmacol. Bull. Jap. Pharm. Soc. 25: 291-301, 2002.
    • (2002) Biol. Pharmacol. Bull. Jap. Pharm. Soc. , vol.25 , pp. 291-301
    • Balcar, V.J.1
  • 20
    • 3042556105 scopus 로고    scopus 로고
    • Molecular pharmacology of glutamate transporters, EAATs and VGLUTs
    • Shigeri Y., Seal R.P. and Shimamoto K., Molecular pharmacology of glutamate transporters, EAATs and VGLUTs. Brain Res. Rev. 45: 250-265, 2004.
    • (2004) Brain Res. Rev. , vol.45 , pp. 250-265
    • Shigeri, Y.1    Seal, R.P.2    Shimamoto, K.3
  • 21
    • 0035814443 scopus 로고    scopus 로고
    • The glial glutamate transporter GLT is localized both in the vicinity and at a distance from axon terminals in the rat cerebral cortex
    • Minelli A., Barbaresi P., Reimer R.J., Edwards R.J. and Conti F., The glial glutamate transporter GLT is localized both in the vicinity and at a distance from axon terminals in the rat cerebral cortex. Neuroscience 108: 51-59, 2001.
    • (2001) Neuroscience , vol.108 , pp. 51-59
    • Minelli, A.1    Barbaresi, P.2    Reimer, R.J.3    Edwards, R.J.4    Conti, F.5
  • 22
    • 1042279664 scopus 로고    scopus 로고
    • Cloning, transport properties and differential localization of two splice variants of GLT-1 in the rat CNS: Implications for CNS glutamate homeostasis
    • Sullivan R., Rauen T., Fischer F., Wießner M., Grewer C., Bicho A. and Pow D., Cloning, transport properties and differential localization of two splice variants of GLT-1 in the rat CNS: Implications for CNS glutamate homeostasis. Glia 45: 155-169, 2004.
    • (2004) Glia , vol.45 , pp. 155-169
    • Sullivan, R.1    Rauen, T.2    Fischer, F.3    Wießner, M.4    Grewer, C.5    Bicho, A.6    Pow, D.7
  • 23
    • 0035503323 scopus 로고    scopus 로고
    • Physiological genomics of antidepressant targets: Keeping the periphery in mind
    • Blakely R.D., Physiological genomics of antidepressant targets: keeping the periphery in mind. J. Neurosci. 21: 8319-8323, 2001.
    • (2001) J. Neurosci. , vol.21 , pp. 8319-8323
    • Blakely, R.D.1
  • 24
    • 14544279281 scopus 로고    scopus 로고
    • Duloxetine: A dual serotonin-norepinephrine reuptake inhibitor for treatment of major depressive disorder
    • Kirwin J.L. and Goren J.L., Duloxetine: a dual serotonin-norepinephrine reuptake inhibitor for treatment of major depressive disorder. Pharmacotherapy 25: 396-410, 2003.
    • (2003) Pharmacotherapy , vol.25 , pp. 396-410
    • Kirwin, J.L.1    Goren, J.L.2
  • 25
    • 3242784074 scopus 로고    scopus 로고
    • Role of the GABA transporter in epilepsy
    • Richerson G.B. and Wu Y., Role of the GABA transporter in epilepsy. Adv. Exp. Med. Biol. 548: 76-91, 2004.
    • (2004) Adv. Exp. Med. Biol. , vol.548 , pp. 76-91
    • Richerson, G.B.1    Wu, Y.2
  • 26
    • 0034319176 scopus 로고    scopus 로고
    • Strategies for studies of neurotoxic mechanisms involving deficient transport of L-glutamate: Antisense knockout in rat brain in vivo and changes in the neurotransmitter metabolism following inhibition of glutamate transport in guinea pig brain slices
    • Rae C., Lawrance M.L., Dias L.S., Provis T., Bubb W.A. and Balcar V.J., Strategies for studies of neurotoxic mechanisms involving deficient transport of L-glutamate: antisense knockout in rat brain in vivo and changes in the neurotransmitter metabolism following inhibition of glutamate transport in guinea pig brain slices. Brain Res. Bull. 54: 373-381, 2000.
    • (2000) Brain Res. Bull. , vol.54 , pp. 373-381
    • Rae, C.1    Lawrance, M.L.2    Dias, L.S.3    Provis, T.4    Bubb, W.A.5    Balcar, V.J.6
  • 27
    • 12944287763 scopus 로고    scopus 로고
    • Association study of polymorphism in the excitatory amino acid transporter 2 gene (SLCIA2) with schizophrenia
    • Deng X.D., Shibata H., Ninomiya H., Tashiro N., Iwata N., Ozaki N. and Fukumaki Y. Association study of polymorphism in the excitatory amino acid transporter 2 gene (SLCIA2) with schizophrenia. BioMed Central Psychiatry 4: 21, 2004. http://www.biomedcentral.com/1471-244X/4/21.
    • (2004) BioMed Central Psychiatry , vol.4 , pp. 21
    • Deng, X.D.1    Shibata, H.2    Ninomiya, H.3    Tashiro, N.4    Iwata, N.5    Ozaki, N.6    Fukumaki, Y.7
  • 28
    • 0032694066 scopus 로고    scopus 로고
    • NMDA receptor hypofunction model of schizophrenia
    • Olney J.W., Newcomer J.W. and Farber N.B., NMDA receptor hypofunction model of schizophrenia. J. Psych. Res. 33: 523-533, 1999.
    • (1999) J. Psych. Res. , vol.33 , pp. 523-533
    • Olney, J.W.1    Newcomer, J.W.2    Farber, N.B.3
  • 29
    • 0023215296 scopus 로고
    • Implications of normal brain development for the pathogenesis of schizophrenia
    • Weinberger D.R, Implications of normal brain development for the pathogenesis of schizophrenia. Arch. Gen. Psych. 44: 660-669, 1987.
    • (1987) Arch. Gen. Psych. , vol.44 , pp. 660-669
    • Weinberger, D.R.1
  • 30
    • 23744444855 scopus 로고    scopus 로고
    • Cognitive dysfunction in schizophrenia: Glutamatergic hypoactivity and dopaminergic failure
    • Holcomb H.H., Rowland L.M. and Tagamets M.A., Cognitive dysfunction in schizophrenia: glutamatergic hypoactivity and dopaminergic failure. Drug Discovery Today: Disease Mech. 1: 435-439, 2004.
    • (2004) Drug Discovery Today: Disease Mech. , vol.1 , pp. 435-439
    • Holcomb, H.H.1    Rowland, L.M.2    Tagamets, M.A.3
  • 31
    • 0037093781 scopus 로고    scopus 로고
    • Stress activation of glutamate neurotransmission in the prefrontal cortex: Implication for dopamine-associated psychiatric disorders
    • Moghaddam B., Stress activation of glutamate neurotransmission in the prefrontal cortex: implication for dopamine-associated psychiatric disorders. Biol. Psych. 51: 775-787, 2002.
    • (2002) Biol. Psych. , vol.51 , pp. 775-787
    • Moghaddam, B.1
  • 32
    • 0034930589 scopus 로고    scopus 로고
    • Effect of schizophrenia on frontotemporal activity during word encoding and recognition: A PET cerebral blood flow study
    • Ragland J.D., Gur R.C., Raz J, Schroeder L., Kohler C.G., Smith R.J., Alavi A. and Gur R.E., Effect of schizophrenia on frontotemporal activity during word encoding and recognition: A PET cerebral blood flow study. Am. J. Psych. 158: 1114-1125, 2001.
    • (2001) Am. J. Psych. , vol.158 , pp. 1114-1125
    • Ragland, J.D.1    Gur, R.C.2    Raz, J.3    Schroeder, L.4    Kohler, C.G.5    Smith, R.J.6    Alavi, A.7    Gur, R.E.8
  • 33
    • 0038061503 scopus 로고    scopus 로고
    • Association between regional cerebral blood flow and eye-tracking performance and the Wisconsin card sorting test in schizophrenics: A single photon emision computed tomography study
    • Yang Y.K., Chen C.C., Lee I.H., Chou Y.H., Chiu N.T., Jeffries K.J., Tsai T.T. and Yeh T.L., Association between regional cerebral blood flow and eye-tracking performance and the Wisconsin card sorting test in schizophrenics: a single photon emision computed tomography study. Psych. Res.: Neuroimaging 123: 37-48, 2003.
    • (2003) Psych. Res.: Neuroimaging , vol.123 , pp. 37-48
    • Yang, Y.K.1    Chen, C.C.2    Lee, I.H.3    Chou, Y.H.4    Chiu, N.T.5    Jeffries, K.J.6    Tsai, T.T.7    Yeh, T.L.8
  • 35
    • 0346367105 scopus 로고    scopus 로고
    • Bringing order to the glutamate chaos in schizophrenia. Minireview
    • Moghaddam B., Bringing order to the glutamate chaos in schizophrenia. Minireview. Neuron 40: 881-884, 2004.
    • (2004) Neuron , vol.40 , pp. 881-884
    • Moghaddam, B.1
  • 36
    • 2342582130 scopus 로고    scopus 로고
    • NMDA receptor function, neuroplasticity and the pathophysiology of schizophrenia
    • Coyle J.T. and Tsai G., NMDA receptor function, neuroplasticity and the pathophysiology of schizophrenia. In. Rev. Neurobiol. 59: 491-515, 2004.
    • (2004) In. Rev. Neurobiol. , vol.59 , pp. 491-515
    • Coyle, J.T.1    Tsai, G.2
  • 37
    • 11844304923 scopus 로고    scopus 로고
    • Decreased expression of vesicular glutamate transporter 1 and complexin II mRNA in schizophrenia: Further evidence for a synaptic pathology affecting glutamate neurons
    • Eastwood S.L. and Harrison P.J., Decreased expression of vesicular glutamate transporter 1 and complexin II mRNA in schizophrenia: further evidence for a synaptic pathology affecting glutamate neurons. Schizophrenia Res. 73: 159-172, 2005.
    • (2005) Schizophrenia Res. , vol.73 , pp. 159-172
    • Eastwood, S.L.1    Harrison, P.J.2
  • 39
    • 0037255437 scopus 로고    scopus 로고
    • Can inhibition of glutamate transport contribute to the action of neuroleptics?
    • Prague
    • Stanton D., Liao L.P., Rae C., Bubb W.A., Moussa C.E.-H. and Balcar V.J., Can inhibition of glutamate transport contribute to the action of neuroleptics?. Psychiatrie (Prague) 7: 6-11, 2003.
    • (2003) Psychiatrie , vol.7 , pp. 6-11
    • Stanton, D.1    Liao, L.P.2    Rae, C.3    Bubb, W.A.4    Moussa, C.E.-H.5    Balcar, V.J.6
  • 40
    • 0032484645 scopus 로고    scopus 로고
    • Chronic neuroleptic treatment alters expression of glial glutamate transporter GLT-1 mRNA in the striatum
    • Schneider J.S., Wade T. and Lidsky T.I., Chronic neuroleptic treatment alters expression of glial glutamate transporter GLT-1 mRNA in the striatum. Neuroreport 9: 133-136, 1998.
    • (1998) Neuroreport , vol.9 , pp. 133-136
    • Schneider, J.S.1    Wade, T.2    Lidsky, T.I.3
  • 41
    • 0032831787 scopus 로고    scopus 로고
    • Chronic haloperidol treatment impairs glutamate transport in the rat striatum
    • De Souza I.E., McBean G.J. and Meredith G.E., Chronic haloperidol treatment impairs glutamate transport in the rat striatum. Eur. J. Pharmacol. 382: 139-142, 1999.
    • (1999) Eur. J. Pharmacol. , vol.382 , pp. 139-142
    • De Souza, I.E.1    McBean, G.J.2    Meredith, G.E.3
  • 43
    • 0037272236 scopus 로고    scopus 로고
    • Clozapine-induced reduction of glutamate transport in the frontal cortex is not mediated by GLAST and EAAC1
    • Melone M, Bragina L. and Conti F., Clozapine-induced reduction of glutamate transport in the frontal cortex is not mediated by GLAST and EAAC1. Mol. Psych. 8: 12-13, 2003.
    • (2003) Mol. Psych. , vol.8 , pp. 12-13
    • Melone, M.1    Bragina, L.2    Conti, F.3
  • 44
    • 20044382110 scopus 로고    scopus 로고
    • Clozapine reduces GLT-1 expression and glutamate uptake in astrocyte cultures
    • Vallejo-Illaramendi A., Torre-Ramos M., Melone M., Conti F. and Matute C., Clozapine reduces GLT-1 expression and glutamate uptake in astrocyte cultures. Glia 50: 276-279, 2005.
    • (2005) Glia , vol.50 , pp. 276-279
    • Vallejo-Illaramendi, A.1    Torre-Ramos, M.2    Melone, M.3    Conti, F.4    Matute, C.5
  • 45
    • 0038641323 scopus 로고    scopus 로고
    • Decreased gene expression of glial and neuronal glutamate transporters after chronic antipsychotic treatment in rat brain
    • Schmitt A., Zink M., Petroianu G., May B., Brans D.F. and Henn F.A., Decreased gene expression of glial and neuronal glutamate transporters after chronic antipsychotic treatment in rat brain. Neurosci. Lett. 347: 81-84, 2003.
    • (2003) Neurosci. Lett. , vol.347 , pp. 81-84
    • Schmitt, A.1    Zink, M.2    Petroianu, G.3    May, B.4    Brans, D.F.5    Henn, F.A.6
  • 46
    • 13544263608 scopus 로고    scopus 로고
    • Increased expression of the astrocytic glutamate transporter GLT in the prefrontal cortex of schizophrenics
    • Matute C., Melone M., Vallejo-Illarramendi A. and Conti F., Increased expression of the astrocytic glutamate transporter GLT in the prefrontal cortex of schizophrenics. Glia 49: 451-455, 2005.
    • (2005) Glia , vol.49 , pp. 451-455
    • Matute, C.1    Melone, M.2    Vallejo-Illarramendi, A.3    Conti, F.4
  • 47
    • 0034849588 scopus 로고    scopus 로고
    • Expression of excitatory amino acid transporter transcripts in the thalamus of subjects with schizophrenia
    • Smith R.E., Haroutian V., Davis K.L. and Meador-Woodruff J.H., Expression of excitatory amino acid transporter transcripts in the thalamus of subjects with schizophrenia. Am. J. Psych. 158: 1393-1399, 2001.
    • (2001) Am. J. Psych. , vol.158 , pp. 1393-1399
    • Smith, R.E.1    Haroutian, V.2    Davis, K.L.3    Meador-Woodruff, J.H.4
  • 49
    • 0041736717 scopus 로고    scopus 로고
    • Regulation of glial glutamate transporter expression by growth factors
    • Figiel M., Maucher T., Rozyczka J., Bayatti N. and Engele J., Regulation of glial glutamate transporter expression by growth factors. Exp. Neurol. 183: 124-135, 2003.
    • (2003) Exp. Neurol. , vol.183 , pp. 124-135
    • Figiel, M.1    Maucher, T.2    Rozyczka, J.3    Bayatti, N.4    Engele, J.5
  • 50
    • 18444385647 scopus 로고    scopus 로고
    • The neurodevelopmental model schizophrenia: Update 2005
    • Rappoport J.L., Addington A.M. and Frangon S., The neurodevelopmental model schizophrenia: update 2005. Mol. Psych. 10: 434-449, 2005.
    • (2005) Mol. Psych. , vol.10 , pp. 434-449
    • Rappoport, J.L.1    Addington, A.M.2    Frangon, S.3
  • 51
    • 0029885882 scopus 로고    scopus 로고
    • Glutamate mRNA expression in proliferative zones of the developing and adult murine CNS
    • Sutherland M.L., Delaney T.L. and Noebels J.L., Glutamate mRNA expression in proliferative zones of the developing and adult murine CNS. J. Neurosci. 16: 2191-2207, 1996.
    • (1996) J. Neurosci. , vol.16 , pp. 2191-2207
    • Sutherland, M.L.1    Delaney, T.L.2    Noebels, J.L.3
  • 52
    • 0030782403 scopus 로고    scopus 로고
    • Glutamate transporter protein subtypes are expressed differentially during rat CNS development
    • Furuta A., Rothstein J.D. and Martin L.J., Glutamate transporter protein subtypes are expressed differentially during rat CNS development. J. Neurosci. 17: 8363-8375, 1997.
    • (1997) J. Neurosci. , vol.17 , pp. 8363-8375
    • Furuta, A.1    Rothstein, J.D.2    Martin, L.J.3
  • 53
    • 0032401003 scopus 로고    scopus 로고
    • Glutamate transport in cultures from developing avian cerebellum: Presence of GLT-1 immunoreactivity in Purkinje neurons
    • Meaney J.A., Balcar V.J., Rothstein J.D. and Jeffrey P.J., Glutamate transport in cultures from developing avian cerebellum: Presence of GLT-1 immunoreactivity in Purkinje neurons. J. Neurosci. Res. 54: 595-603, 1998.
    • (1998) J. Neurosci. Res. , vol.54 , pp. 595-603
    • Meaney, J.A.1    Balcar, V.J.2    Rothstein, J.D.3    Jeffrey, P.J.4
  • 54
    • 0032146774 scopus 로고    scopus 로고
    • Glutamate transporter GLT-1 is transiently localized on growing axons of the mouse spinal cord before establishing astrocytic expression
    • Yamada K., Watanabe M., Shibata T., Nagashima M., Tanaka K. and Inoue Y., Glutamate transporter GLT-1 is transiently localized on growing axons of the mouse spinal cord before establishing astrocytic expression. J. Neurosci. 18: 5706-5713, 1998.
    • (1998) J. Neurosci. , vol.18 , pp. 5706-5713
    • Yamada, K.1    Watanabe, M.2    Shibata, T.3    Nagashima, M.4    Tanaka, K.5    Inoue, Y.6
  • 55
    • 0034006904 scopus 로고    scopus 로고
    • Transient expression of the glial glutamate transporters GLAST and GLT in hippocampal neurones in primary culture
    • Plachez C., Danbolt N.C. and Recasens M., Transient expression of the glial glutamate transporters GLAST and GLT in hippocampal neurones in primary culture. J. Neurosci. Res. 59: 587-593, 2000.
    • (2000) J. Neurosci. Res. , vol.59 , pp. 587-593
    • Plachez, C.1    Danbolt, N.C.2    Recasens, M.3
  • 58
    • 30544432378 scopus 로고    scopus 로고
    • Impaired CNS development in mice lacking astroglial glutamate transporters
    • Tanaka K., Impaired CNS development in mice lacking astroglial glutamate transporters. The World J. Biol. Psych. 5(S1) 163, 2004.
    • (2004) The World J. Biol. Psych. , vol.5 , Issue.S1 , pp. 163
    • Tanaka, K.1
  • 59
    • 0037103860 scopus 로고    scopus 로고
    • Expression of glutamate transporters and ionotropic glutamate receptors in GLAST knockout mice
    • Ueda Y., Doi T., Tsuru N., Tokumaru J. and Mitsuyama Y., Expression of glutamate transporters and ionotropic glutamate receptors in GLAST knockout mice. Mol. Brain Res. 104: 120-126, 2002.
    • (2002) Mol. Brain Res. , vol.104 , pp. 120-126
    • Ueda, Y.1    Doi, T.2    Tsuru, N.3    Tokumaru, J.4    Mitsuyama, Y.5
  • 62
    • 0035863166 scopus 로고    scopus 로고
    • Prenatal exposure to maternal infection alters cytokine expression in the placenta, amniotic fluid, and fetal brain
    • Urakubo A., Jarskog L.F., Lieberman J.A. and Gilmore J.H., Prenatal exposure to maternal infection alters cytokine expression in the placenta, amniotic fluid, and fetal brain. Schizophrenia. Res. 47: 27-36, 2001.
    • (2001) Schizophrenia. Res. , vol.47 , pp. 27-36
    • Urakubo, A.1    Jarskog, L.F.2    Lieberman, J.A.3    Gilmore, J.H.4
  • 63
    • 20144381062 scopus 로고    scopus 로고
    • Lipopolysaccharide increases microglial GLT-1 expression and glutamate uptake capacity in vitro by a mechanism dependent on TNF-α
    • Persson M., Brantefjord M., Hansson E. and Ronnback L., Lipopolysaccharide increases microglial GLT-1 expression and glutamate uptake capacity in vitro by a mechanism dependent on TNF-α. Glia. 51: 111-120, 2005.
    • (2005) Glia , vol.51 , pp. 111-120
    • Persson, M.1    Brantefjord, M.2    Hansson, E.3    Ronnback, L.4
  • 64
    • 25444518030 scopus 로고    scopus 로고
    • Quinolinic acid, N-methyl-D-aspartate receptor and schizophrenia: Testing an integrative theory
    • Yukio Yoneda (Eds)
    • Št'astný F., Tejkalová H., Skuba I., Balcar V.J. and Yoneda Y., Quinolinic acid, N-methyl-D-aspartate receptor and schizophrenia: Testing an integrative theory. In: Yukio Yoneda (Eds), Amino Acid Signalling 04. pp. 67-83, 2005.
    • (2005) Amino Acid Signalling , vol.4 , pp. 67-83
    • Št'astný, F.1    Tejkalová, H.2    Skuba, I.3    Balcar, V.J.4    Yoneda, Y.5
  • 66
    • 3242669826 scopus 로고    scopus 로고
    • Quinolinic acid promotes seizures and decreases glutamate uptake in young rats: Reversal by orally administered guanosine
    • de Oliveirs D.L., Horn J.F., Rodrigues J.M., Frizzo M.E.S., Moriguchi E., Souza D.O. and Wofchuk S., Quinolinic acid promotes seizures and decreases glutamate uptake in young rats: reversal by orally administered guanosine. Brain Res. 1018: 48-54, 2004.
    • (2004) Brain Res. , vol.1018 , pp. 48-54
    • De Oliveirs, D.L.1    Horn, J.F.2    Rodrigues, J.M.3    Frizzo, M.E.S.4    Moriguchi, E.5    Souza, D.O.6    Wofchuk, S.7
  • 67
    • 0033945533 scopus 로고    scopus 로고
    • Human T-cell lymphotropic virus type 1-infected T lymphocytes impair catabolism and uptake of glutamate by astrocytes via Tax-1 and tumor necrosis factor alpha
    • Szymocha R., Akaoka H., Dutuit M., Malcus C., Didier-Bazes M., Belin M.F. and Giraudon P., Human T-cell lymphotropic virus type 1-infected T lymphocytes impair catabolism and uptake of glutamate by astrocytes via Tax-1 and tumor necrosis factor alpha. J. Virol. 74: 6433-6441, 2000.
    • (2000) J. Virol. , vol.74 , pp. 6433-6441
    • Szymocha, R.1    Akaoka, H.2    Dutuit, M.3    Malcus, C.4    Didier-Bazes, M.5    Belin, M.F.6    Giraudon, P.7
  • 68
    • 5644256132 scopus 로고    scopus 로고
    • Glutamate transporters and metabotropic receptors regulate excitatory neurotransmission in the medial entorhinal cortex of the rat
    • Iserhot C., Gebhardt C., Schmiz D. and Heinemann U., Glutamate transporters and metabotropic receptors regulate excitatory neurotransmission in the medial entorhinal cortex of the rat. Brain Res. 1027: 151-160, 2004.
    • (2004) Brain Res. , vol.1027 , pp. 151-160
    • Iserhot, C.1    Gebhardt, C.2    Schmiz, D.3    Heinemann, U.4
  • 69
    • 0347722422 scopus 로고    scopus 로고
    • Dopamine-glutamate interaction in the control of cell excitability in medial prefrontal cortical pyramidal neurons
    • Tseng K.Y. and O'Donnell P., Dopamine-glutamate interaction in the control of cell excitability in medial prefrontal cortical pyramidal neurons. Ann. NY Acad. Sci. 1003: 476-478, 2003.
    • (2003) Ann. NY Acad. Sci. , vol.1003 , pp. 476-478
    • Tseng, K.Y.1    O'Donnell, P.2
  • 71
    • 0038487674 scopus 로고    scopus 로고
    • Presynaptic depression of glutamatergic synaptic transmission by D1-like dopamine receptor activation in the avian basal ganglia
    • Ding L., Perkel D.J. and Farries M.A., Presynaptic depression of glutamatergic synaptic transmission by D1-like dopamine receptor activation in the avian basal ganglia. J. Neurosci. 23: 6086-6095, 2003.
    • (2003) J. Neurosci. , vol.23 , pp. 6086-6095
    • Ding, L.1    Perkel, D.J.2    Farries, M.A.3
  • 72
    • 0035426211 scopus 로고    scopus 로고
    • Dopamine D1 receptor-dependent trafficking of striatal NMDA glutamate receptors to the postsynaptic membrane
    • Dunah A.W. and Standaert D.G., Dopamine D1 receptor-dependent trafficking of striatal NMDA glutamate receptors to the postsynaptic membrane. J. Neurosci. 21: 5546-5558, 2001.
    • (2001) J. Neurosci. , vol.21 , pp. 5546-5558
    • Dunah, A.W.1    Standaert, D.G.2
  • 73
    • 0037059384 scopus 로고    scopus 로고
    • Sensitization of glutamate release and N-methyl-D-aspartate receptor response by transient dopamine pretreatment in prefrontal cortex of rats
    • Takita M., Kawashirna T., Kaneko H., Suzuki S.S. and Yokoi H., Sensitization of glutamate release and N-methyl-D-aspartate receptor response by transient dopamine pretreatment in prefrontal cortex of rats. Neurosci. Lett. 317: 97-100, 2002.
    • (2002) Neurosci. Lett. , vol.317 , pp. 97-100
    • Takita, M.1    Kawashirna, T.2    Kaneko, H.3    Suzuki, S.S.4    Yokoi, H.5
  • 74
    • 0035191981 scopus 로고    scopus 로고
    • Nigrostriatal denervation does not affect glutamate transporter mRNA expression but subsequent levodopa treatment selectively increases GLT1 mRNA and protein expression in the rat striatum
    • Liévens J.C., Salin P., Nieoullon A. and Kerkerian-Le Goff L., Nigrostriatal denervation does not affect glutamate transporter mRNA expression but subsequent levodopa treatment selectively increases GLT1 mRNA and protein expression in the rat striatum. J. Neurochem. 79: 893-902, 2001.
    • (2001) J. Neurochem. , vol.79 , pp. 893-902
    • Liévens, J.C.1    Salin, P.2    Nieoullon, A.3    Kerkerian-Le Goff, L.4
  • 76
    • 0034038270 scopus 로고    scopus 로고
    • Epidermal growth factor receptor agonists increase expresssion of glutamate transporter GLT-1 in astrocytes through pathways dependent on phosphatidylinositol 3-kinase and transcription factor NF-κB
    • Zelenaia O., Schlag B.D., Gochenauer G.E., Ganel R., Song W., Beesley J.S., Grinspan J.B., Rothstein J.D. and Robinson M.B., Epidermal growth factor receptor agonists increase expresssion of glutamate transporter GLT-1 in astrocytes through pathways dependent on phosphatidylinositol 3-kinase and transcription factor NF-κB. Mol. Pharmacol. 57: 667-678, 2000.
    • (2000) Mol. Pharmacol. , vol.57 , pp. 667-678
    • Zelenaia, O.1    Schlag, B.D.2    Gochenauer, G.E.3    Ganel, R.4    Song, W.5    Beesley, J.S.6    Grinspan, J.B.7    Rothstein, J.D.8    Robinson, M.B.9
  • 77
    • 11244320506 scopus 로고    scopus 로고
    • Differential expression of glutamate transporters EAAT1 and EAAT2 in mice deficient for PACAP-type I receptor
    • Zink M., Schmitt A., Henn F.A. and Gass P., Differential expression of glutamate transporters EAAT1 and EAAT2 in mice deficient for PACAP-type I receptor. J. Neur. Trans. 111: 1537-1542, 2004.
    • (2004) J. Neur. Trans. , vol.111 , pp. 1537-1542
    • Zink, M.1    Schmitt, A.2    Henn, F.A.3    Gass, P.4
  • 78
    • 0032937403 scopus 로고    scopus 로고
    • A pharmacological review of competitive inhibitors and substrates of high-affinity, sodium-dependent glutamate transport in the central nervous system
    • Bridges R.J., Kavanaugh M.P. and Chamberlin A.R., A pharmacological review of competitive inhibitors and substrates of high-affinity, sodium-dependent glutamate transport in the central nervous system. Curr. Pharm. Des. 5: 363-379, 1999.
    • (1999) Curr. Pharm. Des. , vol.5 , pp. 363-379
    • Bridges, R.J.1    Kavanaugh, M.P.2    Chamberlin, A.R.3
  • 79
    • 0344450761 scopus 로고    scopus 로고
    • Transient inhibition of glutamate uptake in vivo induces neurodegeneration when energy metabolism is impaired
    • Sanchez-Carbente M.R. and Massieu L., Transient inhibition of glutamate uptake in vivo induces neurodegeneration when energy metabolism is impaired. J. Neurochem. 72: 129-138, 1999.
    • (1999) J. Neurochem. , vol.72 , pp. 129-138
    • Sanchez-Carbente, M.R.1    Massieu, L.2
  • 80
    • 0344980746 scopus 로고    scopus 로고
    • Glutamate uptake inhibitor L-trans-pyrrolidine-2,4-dicarboxylate becomes neurotoxic in the presence of subthreshold concentrations of mitochondrial toxin 3-nitropropionate: Involvement of mitochondrial reducing activity and ATP production
    • Garcia O. and Massieu L., Glutamate uptake inhibitor L-trans-pyrrolidine- 2,4-dicarboxylate becomes neurotoxic in the presence of subthreshold concentrations of mitochondrial toxin 3-nitropropionate: involvement of mitochondrial reducing activity and ATP production. J Neurosci. Res. 74: 956-966, 2003.
    • (2003) J Neurosci. Res. , vol.74 , pp. 956-966
    • Garcia, O.1    Massieu, L.2
  • 81
    • 0033501641 scopus 로고    scopus 로고
    • Glutamate induces rapid upregulation of glutamate transport and cell-surface expression of GLAST
    • Duan S., Anderson C.M., Stein B. and Swanson R.A., Glutamate induces rapid upregulation of glutamate transport and cell-surface expression of GLAST. J. Neurosci. 19: 10193-10200, 1999.
    • (1999) J. Neurosci. , vol.19 , pp. 10193-10200
    • Duan, S.1    Anderson, C.M.2    Stein, B.3    Swanson, R.A.4
  • 82
    • 0036678633 scopus 로고    scopus 로고
    • Neuronal-induced and glutamate-dependent activation of glial glutamate transporter function
    • Poitry-Yamate C.L., Vutskits L. and Rauen T., Neuronal-induced and glutamate-dependent activation of glial glutamate transporter function. J. Neurochem. 82: 987-997, 2002.
    • (2002) J. Neurochem. , vol.82 , pp. 987-997
    • Poitry-Yamate, C.L.1    Vutskits, L.2    Rauen, T.3
  • 83
    • 0036274472 scopus 로고    scopus 로고
    • Regulated trafficking of neurotransmitter transporters: Common notes but different melodies
    • Robinson M.B., Regulated trafficking of neurotransmitter transporters: common notes but different melodies. J. Neurochem. 80: 1-11, 2002.
    • (2002) J. Neurochem. , vol.80 , pp. 1-11
    • Robinson, M.B.1
  • 85
    • 0036316619 scopus 로고    scopus 로고
    • Antagonists of protein kinase C inhibit rat retinal glutamate transport activity in situ
    • Bull N.D. and Barnett N.L., Antagonists of protein kinase C inhibit rat retinal glutamate transport activity in situ. J. Neurochem. 81: 472-480, 2002.
    • (2002) J. Neurochem. , vol.81 , pp. 472-480
    • Bull, N.D.1    Barnett, N.L.2
  • 86
    • 0041802953 scopus 로고    scopus 로고
    • Rottlerin, an inhibitor of protein kinase C-δ (PKC-δ), inhibits astrocytic glutamate transport activity and reduces GLAST immunoreactivity by a mechanism that appears to be PKC-δ-independent
    • Susarla B.T.S. and Robinson M.B., Rottlerin, an inhibitor of protein kinase C-δ (PKC-δ), inhibits astrocytic glutamate transport activity and reduces GLAST immunoreactivity by a mechanism that appears to be PKC-δ-independent. J. Neurochem. 86: 635-645, 2003.
    • (2003) J. Neurochem. , vol.86 , pp. 635-645
    • Susarla, B.T.S.1    Robinson, M.B.2
  • 87
    • 0030870286 scopus 로고    scopus 로고
    • +-ATPase activity in astrocytes via activation of a distinct subunit highly sensitive to ouabain
    • +-ATPase activity in astrocytes via activation of a distinct subunit highly sensitive to ouabain. J. Neurochem. 69: 2132-2137, 1997.
    • (1997) J. Neurochem. , vol.69 , pp. 2132-2137
    • Pellerin, L.1    Magistretti, P.J.2
  • 88
    • 0033774057 scopus 로고    scopus 로고
    • + pump in L-glutamate clearance by cultured rat cortical astrocytes
    • + pump in L-glutamate clearance by cultured rat cortical astrocytes. Biol. Pharm. Bull. 23: 1051-1054, 2000.
    • (2000) Biol. Pharm. Bull. , vol.23 , pp. 1051-1054
    • Abe, K.1    Saito, H.2
  • 89
    • 0035044736 scopus 로고    scopus 로고
    • Local injection of antisense oligonucleotides targeted to the glial glutamate transporter GLAST decreases the metabolic response to somatosensory activation
    • Cholet N., Pellerin L., Welker E., Lacombe P., Seylaz J., Magistretti P.J. and Bonvento G., Local injection of antisense oligonucleotides targeted to the glial glutamate transporter GLAST decreases the metabolic response to somatosensory activation. J. Cereb. Blood Flow 21: 404-412, 2001.
    • (2001) J. Cereb. Blood Flow , vol.21 , pp. 404-412
    • Cholet, N.1    Pellerin, L.2    Welker, E.3    Lacombe, P.4    Seylaz, J.5    Magistretti, P.J.6    Bonvento, G.7
  • 90
    • 0036266311 scopus 로고    scopus 로고
    • +-ATPase alpha 2-subunit and the glutamate transporters GLAST and GLT in the rat somatosensory cortex
    • +-ATPase alpha 2-subunit and the glutamate transporters GLAST and GLT in the rat somatosensory cortex. Cereb. Cortex 12: 515-525, 2002.
    • (2002) Cereb. Cortex , vol.12 , pp. 515-525
    • Cholet, N.1    Pellerin, L.2    Magistretti, P.J.3    Hamel, E.4
  • 93
    • 30544441826 scopus 로고
    • +-ATPase in red cell ghosts of schizophrenics
    • +-ATPase in red cell ghosts of schizophrenics. Nature 201: 823, 1964.
    • (1964) Nature , vol.201 , pp. 823
    • Parker, J.C.1    Hoffman, J.F.2
  • 94
    • 0015318850 scopus 로고
    • Epilepsy, schizophrenia and sodium-potassium-ATPase
    • Viukari M., Epilepsy, schizophrenia and sodium-potassium-ATPase. Lancet 1(7753)749, 1972.
    • (1972) Lancet , vol.1 , Issue.7753 , pp. 749
    • Viukari, M.1
  • 95
    • 0028279398 scopus 로고
    • Decreased activity of erythrocyte membrane ATPases in depression and schizophrenia
    • Rybakowski J.K. and Lehman W., Decreased activity of erythrocyte membrane ATPases in depression and schizophrenia. Neuropsychobiol. 30: 11-14, 1994.
    • (1994) Neuropsychobiol. , vol.30 , pp. 11-14
    • Rybakowski, J.K.1    Lehman, W.2
  • 96
    • 0344851743 scopus 로고    scopus 로고
    • +-ATPase inhibition in relation to neurological disorders
    • +-ATPase inhibition in relation to neurological disorders. Int. J. Neurosci. 113: 1705-1717, 2003.
    • (2003) Int. J. Neurosci. , vol.113 , pp. 1705-1717
    • Kurup, R.K.1    Kurup, P.A.2
  • 97
    • 0742306071 scopus 로고    scopus 로고
    • Neurotranmitter transporters: Why dance with so many partners?
    • Gonzalez M.I. and Robinson M.B., Neurotranmitter transporters: why dance with so many partners?. Curr. Opinion Pharmacol. 4: 30-35, 2004.
    • (2004) Curr. Opinion Pharmacol. , vol.4 , pp. 30-35
    • Gonzalez, M.I.1    Robinson, M.B.2
  • 99
    • 3242693273 scopus 로고    scopus 로고
    • Glutamate transporter cluster formation in astrocytic processes regulates glutamate uptake activity
    • Zhou J.-Z. and Sutherland M.L., Glutamate transporter cluster formation in astrocytic processes regulates glutamate uptake activity. J Neurosci 24: 6301-6306, 2004.
    • (2004) J Neurosci , vol.24 , pp. 6301-6306
    • Zhou, J.-Z.1    Sutherland, M.L.2
  • 100
    • 33244456070 scopus 로고    scopus 로고
    • Glutamate transport - Target for the next generation of neuroleptics?
    • Prague
    • Balcar V.J. and Nanitsos E.K., Glutamate transport - Target for the next generation of neuroleptics?. Psychiatrie (Prague) 29 S1: 19-23, 2005.
    • (2005) Psychiatrie , vol.29 S1 , pp. 19-23
    • Balcar, V.J.1    Nanitsos, E.K.2
  • 101
    • 0347091932 scopus 로고    scopus 로고
    • Glutamate, dopamine, and schizophrenia. from pathophysiology to treatment
    • Laruelle M., Kegeles L.S. and Abi-Dargham A., Glutamate, dopamine, and schizophrenia. From pathophysiology to treatment. Ann. NY Acad. Sci. 1003: 138-158, 2003.
    • (2003) Ann. NY Acad. Sci. , vol.1003 , pp. 138-158
    • Laruelle, M.1    Kegeles, L.S.2    Abi-Dargham, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.