Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells

Nucleic Acids Research

Volumn 30, Issue 4, 2002, Pages 1009-1015

  Liu, Nan ^a   Schild, David ^b   Thelen, Michael P ^a   Thompson, Larry H ^a  

^a LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL EXTRACT; DNA HOMOLOG; DOUBLE STRANDED DNA; EPITOPE; PROTEIN CRCC2; PROTEIN XRCC3; RAD51 PROTEIN; RAD51B PROTEIN; RAD51C PROTEIN; RAD51D PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MUTANT; CHICKEN; COMPLEX FORMATION; CONTROLLED STUDY; DNA RECOMBINATION; DNA REPAIR; DNA STRAND BREAKAGE; GENETIC ANALYSIS; HAMSTER; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VIVO STUDY; MOLECULAR STABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RODENT; TWO HYBRID SYSTEM;

ANIMALIA; CRICETINAE; GALLUS GALLUS; RODENTIA;

EID: 0037082427     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/30.4.1009     Document Type: Article

References (38)

1. Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein
2. Cloning of human, mouse and fission yeast recombination genes homologous to RAD51 and recA
3. Catalysis of ATP-dependent homologous DNA pairing and strand exchange by yeast RAD51 protein
4. Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro
5. Activities of human recombination protein Rad51
6. Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinase
7. Rad52 protein stimulates DNA strand exchange by Rad51 and replication protein A
8. Rad54 protein stimulates heteroduplex DNA formation in the synaptic phase of DNA strand exchange via specific interactions with the presynaptic Rad51 nucleoprotein filament
9. Functional differences and interactions among the putative RecA homologs Rad51, Rad55 and Rad57
10. Homologous recombinational repair of DNA ensures mammalian chromosome stability
11. XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages
12. The XRCC2 DNA repair gene from human and mouse encodes a novel member of the recA/RAD51 family
13. Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene
14. Identification of a novel human RAD51 homolog, RAD51B
15. Isolation of novel human and mouse genes of the recA/RAD51 recombination-repair gene family
16. Isolation and characterization of RAD51C, a new human member of the RAD51 family of related genes
17. Identification, characterization and genetic mapping of Rad51d, a new mouse and human RAD51/RecA-related gene
18. Isolation of human and mouse genes based on homology to REC2, a recombinational repair gene from the fungus Ustilago maydis
19. Isolation and cross-sensitivity of X-ray-sensitive mutants of V79-4 hamster cells
20. A Chinese hamster ovary cell line hypersensitive to ionizing radiation and deficient in repair replication
21. Cytogenetic characterization of the ionizing radiation-sensitive Chinese hamster mutant irs1
22. The XRCC2 and XRCC3 repair genes are required for chromosome stability in mammalian cells
23. The Rad51 paralog Rad51B promotes homologous recombinational repair
24. Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs
25. Disruption of muREC2/RAD51L1 in mice results in early embryonic lethality which can be partially rescued in a p53(-/-) background
26. Xrcc2 is required for genetic stability, embryonic neurogenesis and viability in mice
27. Midgestation lethality in mice deficient for the RecA-related gene, Rad51d/Rad5113
28. A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53
29. Targeted disruption of the Rad51 gene leads to lethality in embryonic mice
30. Evidence for simultaneous protein interactions between human Rad51 paralogs
31. The RAD51 family member, RAD51L3, is a DNA-stimulated ATPase that forms a complex with XRCC2
32. Homologous-pairing activity of the human DNA-repair proteins Xrcc3. Rad51C
33. Complex formation by the human RAD51C and XRCC3 recombination repair proteins
34. Re-evaluation of HeLa, HeLa S3 and HEp-2 karyotypes
35. Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes
36. Interactions involving the Rad51 paralogs Rad51C and XRCC3 in human cells
37. Tailed duplex DNA is the preferred substrate for Rad51 protein-mediated homologous pairing
38. Double-strand-break-induced homologous recombination in mammalian cells