Interactions involving the Rad51 paralogs Rad51C and XRCC3 in human cells

Nucleic Acids Research

Volumn 30, Issue 4, 2002, Pages 1001-1008

  Wiese, Claudia ^a,c   Collins, David W ^a   Albala, Joanna S ^b   Thompson, Larry H ^b   Kronenberg, Amy ^a   Schild, David ^a  

^a LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^b LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

^c GSI HELMHOLTZZENTRUM FÜR SCHWERIONENFORSCHUNG GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; DNA HOMOLOG; DOUBLE STRANDED DNA; HISTIDINE; NICKEL; PROTEIN XRCC2; PROTEIN XRCC3; RAD51 PROTEIN; RAD51B PROTEIN; RAD51C PROTEIN; RAD51D PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BACULOVIRUS; CELL LINE; CHICKEN; COMPLEX FORMATION; CONTROLLED STUDY; DIMERIZATION; DNA RECOMBINATION; DNA REPAIR; DNA STRAND BREAKAGE; EXPRESSED SEQUENCE TAG; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; PARALOGY; PRIORITY JOURNAL; PROTEIN ISOLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; RODENT; TWO HYBRID SYSTEM; X RAY;

GALLUS GALLUS; RODENTIA; UNIDENTIFIED BACULOVIRUS;

EID: 0037082443     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/30.4.1001     Document Type: Article

References (43)

1. DNA strand exchange proteins: A biochemical and physical comparison
2. XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages
3. The XRCC2 DNA repair gene from human and mouse encodes a novel member of the recA/RAD51 family
4. Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination
5. Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene
6. XRCC3 promotes homology-directed repair of DNA damage in mammalian cells
7. Isolation of human and mouse genes based on homology to REC2, a recombinational repair gene from the fungus Ustilago maydis
8. Identification of a novel human RAD51 homolog, RAD51B
9. Isolation of novel human and mouse genes of the recA/RAD51 recombination-repair gene family
10. Isolation and characterization of RAD51C, a new human member of the RAD51 family of related genes
11. Identification, characterization and genetic mapping of Rad51d, a new mouse and human RAD51/RecA-related gene
12. Sequence analysis and expression of a novel mouse homolog of Escherichia coli recA gene
13. The contribution of homologous recombination in preserving genome integrity in mammalian cells
14. A surfeit of RAD51-like genes?
15. Homologous recombinational repair of DNA ensures mammalian chromosome stability
16. XRCC3 is required for efficient repair of chromosome breaks by homologous recombination
17. The Rad51 paralog Rad51B promotes homologous recombinational repair
18. Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs
19. Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinase
20. Evidence for simultaneous protein interactions between human Rad51 paralogs
21. The RAD51 family member, RAD51L3, is a DNA-stimulated ATPase that forms a complex with XRCC2
22. XRCC2 is a nuclear RAD51-like protein required for damage-dependent RAD51 focus formation without the need for ATP binding
23. Complex formation by the human RAD51C and XRCC3 recombination repair proteins
24. Homologous-pairing activity of the human DNA-repair proteins Xrcc3.Rad51C
25. Human lymphoblastoid lines from lymph node and spleen
26. Electroporation in 'intracellular' buffer increases cell survival
27. Quantitative assay for mutation in diploid human lymphoblasts using microtiter plates
28. Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations
29. Altered p53 status correlates with differences in sensitivity to radiation-induced mutation and apoptosis in two closely related human lymphoblast lines
30. Absence of radiation-induced G1 arrest in two closely related human lymphoblast cell lines that differ in p53 status
31. The relative radiosensitivity of TK6 and WI-L2-NS lymphoblastoid cells derived from a common source is primarily determined by their p53 mutational status
32. Disruption of muREC2/RAD51L1 in mice results in early embryonic lethality which can be partially rescued in a p53(-/-) background
33. Midgestation lethality in mice deficient for the RecA-related gene, Rad51d/Rad5113
34. Xrcc2 is required for genetic stability, embryonic neurogenesis and viability in mice
35. Inverse dose-rate effect for mutation induction by gamma-rays in human lymphoblasts
36. Elevated recombination in immortal human cells is mediated by HsRAD51 recombinase
37. Different mechanisms of radiation-induced loss of heterozygosity in two human lymphoid cell lines from a single donor
38. The human REC2/RAD51B gene acts as a DNA damage sensor by inducing G1 delay and hypersensitivity to ultraviolet irradiation
39. Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells
40. RAD51C interacts with RAD51B and is central to a larger protein complex in vivo exclusive of RAD51
41. Identification and purification of two distinct complexes containing the five RAD51 paralogs
42. Functional differences and interactions among the putative RecA homologs Rad51, Rad55 and Rad57
43. Complex formation in yeast double-strand break repair: Participation of Rad51, Rad52, Rad55 and Rad57 proteins