A novel role of lactosylceramide in the regulation of lipopolysaccharide/ interferon-γ-mediated inducible nitric oxide synthase gene expression: Implications for neuroinflammatory diseases

Journal of Neuroscience

Volumn 24, Issue 26, 2004, Pages 5942-5954

  Pannu, Ravinder ^a   Won, Je Seong ^a   Khan, Mushfiquddin ^a   Singh, Avtar K ^b   Singh, Inderjit ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Astrocytes; iNOS; Interferon ; Lactosylceramide; Lipopolysaccharide; Spinal cord injury

Indexed keywords

2 DECANOYLAMINO 3 MORPHOLINO 1 PHENYL 1 PROPANOL; ACETYLCYSTEINE; ANTIOXIDANT; ANTISENSE OLIGONUCLEOTIDE; CERAMIDE GLUCOSYLTRANSFERASE; CERAMIDE GLUCOSYLTRANSFERASE INHIBITOR; GALACTOSYLTRANSFERASE; GALT 2 PROTEIN; GAMMA INTERFERON; GLYCOSPHINGOLIPID; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; LACTOSYLCERAMIDE; LACTOSYLCERAMIDE SYNTHASE; LIPOPOLYSACCHARIDE; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE 1; NITRIC OXIDE; PYRROLIDINE DITHIOCARBAMATE; RAS PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; BASSO SCORE; BEATTIE SCORE; BRESNAHAN SCORE; CELL CULTURE; CELL LEVEL; CONTROLLED STUDY; DEMYELINATION; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; GALT 2 GENE; GENE; GENE ACTIVITY; GENE EXPRESSION REGULATION; GENE REPRESSION; GENE SILENCING; IN VIVO STUDY; INFLAMMATION; LIPOGENESIS; NERVE CELL NECROSIS; NEUROINFLAMMATORY DISEASE; NEUROLOGIC DISEASE; NEUROPATHOLOGY; NEWBORN; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN PHOSPHORYLATION; RAT; REPORTER GENE; SCORING SYSTEM; SPINAL CORD INJURY; TISSUE NECROSIS;

ACETYLCYSTEINE; ANIMALS; ANTIGENS, CD; ANTIOXIDANTS; APOPTOSIS; ASTROCYTES; CELLS, CULTURED; DEMYELINATING DISEASES; DRUG EVALUATION, PRECLINICAL; ENZYME INDUCTION; ENZYME INHIBITORS; FATTY ACIDS; FEMALE; GAIT DISORDERS, NEUROLOGIC; GALACTOSYLTRANSFERASES; I-KAPPA B PROTEINS; INFLAMMATION; INTERFERON-GAMMA, RECOMBINANT; LACTOSYLCERAMIDES; LIPOPOLYSACCHARIDES; MORPHOLINES; NERVE TISSUE PROTEINS; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATION-REDUCTION; PHOSPHORYLATION; PROLINE; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SPINAL CORD INJURIES; THIOCARBAMATES; TRANSFECTION;

EID: 3042841602     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1271-04.2004     Document Type: Article

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