Disialoganglioside GD3 is released by microglia and induces oligodendrocyte apoptosis

Cell Death and Differentiation

Volumn 9, Issue 7, 2002, Pages 758-767

  Simon, B M ^a,b   Malisan, F ^c   Testi, R ^c   Nicotera, P ^a,b   Leist, M ^a,d  

^a UNIVERSITY OF KONSTANZ   (Germany)

^b MRC TOXICOLOGY UNIT   (United Kingdom)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

^d H LUNDBECK A S   (Denmark)

Author keywords

Apoptosis; Demyelination; Ganglioside; Microglia; Mitochondria; Oligodendrocyte

Indexed keywords

CASPASE; GANGLIOSIDE; GANGLIOSIDE, GD3; PHOSPHATIDYLSERINE; SIALOGANGLIOSIDES; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CYTOCHROME C; GANGLIOSIDE GD3; PROTEIN BCL 2;

ANIMAL; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; CELL CULTURE; CELL DIFFERENTIATION; CELL NUCLEUS; CELL SURVIVAL; CYTOLOGY; DRUG ANTAGONISM; HUMAN; METABOLISM; MICROGLIA; MITOCHONDRION; MOUSE; OLIGODENDROGLIA; ANIMAL CELL; CELL MEMBRANE; CELL TYPE; CHROMATIN CONDENSATION; CONTROLLED STUDY; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSITIVITY ANALYSIS; STIMULUS RESPONSE;

ANIMALS; APOPTOSIS; CASPASES; CELL DIFFERENTIATION; CELL NUCLEUS; CELL SURVIVAL; CELLS, CULTURED; GANGLIOSIDES; HUMANS; MICE; MICE, INBRED BALB C; MICROGLIA; MITOCHONDRIA; OLIGODENDROGLIA; PHOSPHATIDYLSERINES; ANIMAL; HUMAN; SUPPORT, NON-U.S. GOV'T;

EID: 0035988387     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401027     Document Type: Article

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