-
1
-
-
0026639957
-
Sterol molecule: Structure, biosynthesis and function
-
Bloch K: Sterol molecule: Structure, biosynthesis and function. Steroids (1992) 57(8):378-383.
-
(1992)
Steroids
, vol.57
, Issue.8
, pp. 378-383
-
-
Bloch, K.1
-
2
-
-
0002246524
-
Biosynthesis of mevalonic acid from acetyl-CoA
-
Cane DE Ed, Pergamon Press, Oxford, UK
-
Bochar DA, Friesen JA, Stauffacher CV, Rodwell VW: Biosynthesis of mevalonic acid from acetyl-CoA. In: Comprehensive Natural Product Chemistry. Isoprenoids including Carotenoids and Steroids. Cane DE (Ed), Pergamon Press, Oxford, UK (1999) 2:15-44.
-
(1999)
Comprehensive Natural Product Chemistry. Isoprenoids including Carotenoids and Steroids
, vol.2
, pp. 15-44
-
-
Bochar, D.A.1
Friesen, J.A.2
Stauffacher, C.V.3
Rodwell, V.W.4
-
4
-
-
0033213706
-
The discovery of the mevalonate-independent pathway for isoprenoid biosynthesis in bacteria, algae and higher plants
-
Rohmer M: The discovery of the mevalonate-independent pathway for isoprenoid biosynthesis in bacteria, algae and higher plants. Nat Prod Rep (1999) 16(5):565-574.
-
(1999)
Nat Prod Rep
, vol.16
, Issue.5
, pp. 565-574
-
-
Rohmer, M.1
-
5
-
-
0001692419
-
The biosynthesis of triterpenoids of the hopane series in eubacteria: A mine of new enzyme reactions
-
Rohmer M: The biosynthesis of triterpenoids of the hopane series in eubacteria: A mine of new enzyme reactions. Pure Appl Chem (1993) 65:1293-1298.
-
(1993)
Pure Appl Chem
, vol.65
, pp. 1293-1298
-
-
Rohmer, M.1
-
6
-
-
0024061058
-
Prokaryotic hopanoids: The biosynthesis of the bacteriohopane skeleton. Formation of isoprenic units from two distinct acetate pools and a novel type of carbon/carbon linkage between a triterpene and D-ribose
-
Flesch G, Rohmer M: Prokaryotic hopanoids: The biosynthesis of the bacteriohopane skeleton. Formation of isoprenic units from two distinct acetate pools and a novel type of carbon/carbon linkage between a triterpene and D-ribose. Eur J Biochem (1988) 175(2):405-411.
-
(1988)
Eur J Biochem
, vol.175
, Issue.2
, pp. 405-411
-
-
Flesch, G.1
Rohmer, M.2
-
7
-
-
0027368126
-
Isoprenoid biosynthesis in bacteria: A novel pathway for the early steps leading to isopentenyl diphosphate
-
Rohmer M, Knani M, Simonin P, Sutter B, Sahm H: Isoprenoid biosynthesis in bacteria: A novel pathway for the early steps leading to isopentenyl diphosphate. Biochem J (1993) 295(2):517-524.
-
(1993)
Biochem J
, vol.295
, Issue.2
, pp. 517-524
-
-
Rohmer, M.1
Knani, M.2
Simonin, P.3
Sutter, B.4
Sahm, H.5
-
8
-
-
0029922877
-
Glyceraldehyde 3-phosphate and pyruvate as precursors of isoprenic units in an alternative non-mevalonate pathway for terpenoid biosynthesis
-
Rohmer M, Seemann M, Horbach S, Bringer-Meyer S, Sahm H: Glyceraldehyde 3-phosphate and pyruvate as precursors of isoprenic units in an alternative non-mevalonate pathway for terpenoid biosynthesis. J Am Chem Soc (1996) 118(11):2564-2566.
-
(1996)
J Am Chem Soc
, vol.118
, Issue.11
, pp. 2564-2566
-
-
Rohmer, M.1
Seemann, M.2
Horbach, S.3
Bringer-Meyer, S.4
Sahm, H.5
-
10
-
-
68549086346
-
-
Schwarz M, Arigoni D: kolide biosynthesis Comprehensive Natural Product Chemistry. Isoprenoids including Carotenoids and Steroids. Cane DE (Ed), Pergamon Press, Oxford, UK (1999) 2:367-400.
-
Schwarz M, Arigoni D: kolide biosynthesis Comprehensive Natural Product Chemistry. Isoprenoids including Carotenoids and Steroids. Cane DE (Ed), Pergamon Press, Oxford, UK (1999) 2:367-400.
-
-
-
-
11
-
-
0033513375
-
The 1-deoxy-D-xylulose 5-phosphate pathway of isoprenoid biosynthesis in plants
-
Lichtenthaler HK: The 1-deoxy-D-xylulose 5-phosphate pathway of isoprenoid biosynthesis in plants. Annu Rev Plant Physiol Plant Mol Biol (1999) 50:47-65.
-
(1999)
Annu Rev Plant Physiol Plant Mol Biol
, vol.50
, pp. 47-65
-
-
Lichtenthaler, H.K.1
-
12
-
-
0035478823
-
The non-mevalonate pathway of isoprenoids: Genes, enzymes and intermediates
-
Rohdich F, Kis K, Bacher A, Eisenreich W: The non-mevalonate pathway of isoprenoids: Genes, enzymes and intermediates. Curr Opin Chem Biol (2001) 5(5):535-540.
-
(2001)
Curr Opin Chem Biol
, vol.5
, Issue.5
, pp. 535-540
-
-
Rohdich, F.1
Kis, K.2
Bacher, A.3
Eisenreich, W.4
-
13
-
-
68549093697
-
-
12 in Propionibacterium shermanii. PhD Thesis Nb 10978, Eidgenössische Technische Hochschule, Zürich, Switzerland (1994).
-
12 in Propionibacterium shermanii. PhD Thesis Nb 10978, Eidgenössische Technische Hochschule, Zürich, Switzerland (1994).
-
-
-
-
14
-
-
0030855436
-
Incorporation of 2-C-methyl-D-erythritol, a putative isoprenoid precursor in the mevalonate-independent pathway, into ubiquinone and menaquinone of Escherichia coli
-
Duvold T, Calí P, Bravo J-M, Rohmer M: Incorporation of 2-C-methyl-D-erythritol, a putative isoprenoid precursor in the mevalonate-independent pathway, into ubiquinone and menaquinone of Escherichia coli. Tetrahedron Lett (1997) 38(35):6181- 6184.
-
(1997)
Tetrahedron Lett
, vol.38
, Issue.35
, pp. 6181-6184
-
-
Duvold, T.1
Calí, P.2
Bravo, J.-M.3
Rohmer, M.4
-
15
-
-
0030696041
-
Identification of a thiamin-dependent synthase in Escherichia coli required for the formation of 1-deoxy-D-xylulose 5-phosphate precursor to isoprenoids, thiamin and pyridoxol
-
Sprenger GA, Schörken U, Wiegert T, Grolle S, de Graaf AA, Taylor SV, Begley TP, Bringer-Meyer S, Sahm H: Identification of a thiamin-dependent synthase in Escherichia coli required for the formation of 1-deoxy-D-xylulose 5-phosphate precursor to isoprenoids, thiamin and pyridoxol. Proc Natl Acad Sci USA (1997) 94(24):12857-12862.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.24
, pp. 12857-12862
-
-
Sprenger, G.A.1
Schörken, U.2
Wiegert, T.3
Grolle, S.4
de Graaf, A.A.5
Taylor, S.V.6
Begley, T.P.7
Bringer-Meyer, S.8
Sahm, H.9
-
16
-
-
0032478189
-
Cloning and characterization of a gene from Escherichia coli encoding a transketolase-like enzyme that catalyzes the synthesis of D-1-deoxyxylulose 5-phosphate, a common precursor for isoprenoid, thiamin and pyridoxol biosynthesis
-
Lois LM, Campos N, Putra SR, Danielsen K, Rohmer M, Boronat A: Cloning and characterization of a gene from Escherichia coli encoding a transketolase-like enzyme that catalyzes the synthesis of D-1-deoxyxylulose 5-phosphate, a common precursor for isoprenoid, thiamin and pyridoxol biosynthesis. Proc Natl Acad Sci USA (1998) 95(5):2105-2110.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.5
, pp. 2105-2110
-
-
Lois, L.M.1
Campos, N.2
Putra, S.R.3
Danielsen, K.4
Rohmer, M.5
Boronat, A.6
-
17
-
-
0343614184
-
A family of transketolases that directs isoprenoid biosynthesis via a mevalonate-independent pathway
-
Lange BM, Wildung MR, McCaskill D, Croteau R: A family of transketolases that directs isoprenoid biosynthesis via a mevalonate-independent pathway. Proc Natl Acad Sci USA (1998) 95(5):2100-2104.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.5
, pp. 2100-2104
-
-
Lange, B.M.1
Wildung, M.R.2
McCaskill, D.3
Croteau, R.4
-
18
-
-
0035180811
-
-
Hahn FM, Eubanks LM, Testa CA, Blagg BSJ, Baker JA, Poulter CD: 1-Deoxy-D-xylulose 5-phosphate synthase, the gene product of open reading frame (ORF) 2816 and ORF 2895 in Rhodobacter capsulatus. J Bacteriol (2001) 183(1):1-11.
-
Hahn FM, Eubanks LM, Testa CA, Blagg BSJ, Baker JA, Poulter CD: 1-Deoxy-D-xylulose 5-phosphate synthase, the gene product of open reading frame (ORF) 2816 and ORF 2895 in Rhodobacter capsulatus. J Bacteriol (2001) 183(1):1-11.
-
-
-
-
19
-
-
0034930422
-
Molecular cloning, expression and characterization of the first three genes in the mevalonate-independent isoprenoid pathway in Streptomyces coelicolor
-
Cane DE, Chow C, Lillo A, Kang I: Molecular cloning, expression and characterization of the first three genes in the mevalonate-independent isoprenoid pathway in Streptomyces coelicolor. Bioorg Med Chem (2001) 9(6):1467-1477.
-
(2001)
Bioorg Med Chem
, vol.9
, Issue.6
, pp. 1467-1477
-
-
Cane, D.E.1
Chow, C.2
Lillo, A.3
Kang, I.4
-
20
-
-
0034827891
-
PCR amplification of 1-deoxy-D-xylulose 5-phosphate synthase (dxs) gene from different Streptomyces species: Evidence for the existence of two dxs gene families
-
Li S-M, Wemakor E, Heide L: PCR amplification of 1-deoxy-D-xylulose 5-phosphate synthase (dxs) gene from different Streptomyces species: Evidence for the existence of two dxs gene families. Mol Biol Today (2001) 2(5):61-66.
-
(2001)
Mol Biol Today
, vol.2
, Issue.5
, pp. 61-66
-
-
Li, S.-M.1
Wemakor, E.2
Heide, L.3
-
21
-
-
0032543467
-
Direct formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D-xylulose 5-phosphate by 1-deoxy-D-xylulose 5-phosphate reductoisomerase, a new enzyme in the non-mevalonate pathway to isopentenyl diphosphate
-
Kuzuyama T, Takahashi S, Watanabe H, Seto H: Direct formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D-xylulose 5-phosphate by 1-deoxy-D-xylulose 5-phosphate reductoisomerase, a new enzyme in the non-mevalonate pathway to isopentenyl diphosphate. Tetrahedron Lett (1998) 39(25):4509-4512.
-
(1998)
Tetrahedron Lett
, vol.39
, Issue.25
, pp. 4509-4512
-
-
Kuzuyama, T.1
Takahashi, S.2
Watanabe, H.3
Seto, H.4
-
22
-
-
0032544054
-
A 1-deoxy-D-xylulose 5-phosphate reducto-isomerase catalyzes the formation of 2-C- methyl-D-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis
-
Takahashi S, Kuzuyama T, Watanabe H, Seto H: A 1-deoxy-D-xylulose 5-phosphate reducto-isomerase catalyzes the formation of 2-C- methyl-D-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis. Proc Natl Acad Sci USA (1998) 95(17):9879-9884.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.17
, pp. 9879-9884
-
-
Takahashi, S.1
Kuzuyama, T.2
Watanabe, H.3
Seto, H.4
-
23
-
-
0037039285
-
-
Koppisch AT, Fox DT, Blagg BSJ, Poulter CD: E coli MEP synthase: Steady-state kinetic analysis and substrate binding. Biochemistry1 (2002) 41(1):236-243.
-
Koppisch AT, Fox DT, Blagg BSJ, Poulter CD: E coli MEP synthase: Steady-state kinetic analysis and substrate binding. Biochemistry1 (2002) 41(1):236-243.
-
-
-
-
24
-
-
0036379275
-
Isoprenoid biosynthesis via the methylerythritol phosphate pathway. Mechanistic investigations of the 1-deoxy-D-xylulose 5-phosphate reductoisomerase
-
Hoeffler JF, Tritsch D, Grosdemange-Billiard C, Rohmer M: Isoprenoid biosynthesis via the methylerythritol phosphate pathway. Mechanistic investigations of the 1-deoxy-D-xylulose 5-phosphate reductoisomerase. Eur J Biochem (2002) 269(18):4446-4457.
-
(2002)
Eur J Biochem
, vol.269
, Issue.18
, pp. 4446-4457
-
-
Hoeffler, J.F.1
Tritsch, D.2
Grosdemange-Billiard, C.3
Rohmer, M.4
-
25
-
-
0032693034
-
Cytidine 5'-triphosphate-dependent biosynthesis of isoprenoids: YgbP protein catalyzes the formation of 4-diphosphocytidyl-2-C-methylerythritol
-
Rohdich F, Wungsintaweekul J, Fellermeier M, Sagner S, Herz S, Kis K, Eisenreich W, Bacher A, Zenk MH: Cytidine 5'-triphosphate-dependent biosynthesis of isoprenoids: YgbP protein catalyzes the formation of 4-diphosphocytidyl-2-C-methylerythritol. Proc Natl Acad Sci USA (1999) 96(21):11758-11763.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.21
, pp. 11758-11763
-
-
Rohdich, F.1
Wungsintaweekul, J.2
Fellermeier, M.3
Sagner, S.4
Herz, S.5
Kis, K.6
Eisenreich, W.7
Bacher, A.8
Zenk, M.H.9
-
26
-
-
0033964943
-
Biosynthesis of terpenoids: YchB protein of Escherichia coli phosphorylates the 2-hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
-
Lüttgen H, Rohdich F, Herz S, Wungsintaweekul J, Hecht S, Schuhr CA, Fellermeier M, Sagner S, Zenk MH, Bacher A, Eisenreich W: Biosynthesis of terpenoids: YchB protein of Escherichia coli phosphorylates the 2-hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. Proc Natl Acad Sci USA (2000) 97(3):1062-1067.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.3
, pp. 1062-1067
-
-
Lüttgen, H.1
Rohdich, F.2
Herz, S.3
Wungsintaweekul, J.4
Hecht, S.5
Schuhr, C.A.6
Fellermeier, M.7
Sagner, S.8
Zenk, M.H.9
Bacher, A.10
Eisenreich, W.11
-
27
-
-
0034646297
-
Biosynthesis of terpenoids: YgbB protein converts 4-diphosphocytidyl-2-C-methyl- D-erythritol 2-phosphate to 2C-methyl-D-erythritol 2,4-cyclodiphosphate
-
Herz S, Wungsintaweekul J, Schuhr CA, Hecht S, Lüttgen H, Sagner S, Fellermeier M, Eisenreich W, Zenk MH, Bacher A, Rohdich F: Biosynthesis of terpenoids: YgbB protein converts 4-diphosphocytidyl-2-C-methyl- D-erythritol 2-phosphate to 2C-methyl-D-erythritol 2,4-cyclodiphosphate. Proc Natl Acad Sci USA (2000) 97(6):2486-2490.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.6
, pp. 2486-2490
-
-
Herz, S.1
Wungsintaweekul, J.2
Schuhr, C.A.3
Hecht, S.4
Lüttgen, H.5
Sagner, S.6
Fellermeier, M.7
Eisenreich, W.8
Zenk, M.H.9
Bacher, A.10
Rohdich, F.11
-
28
-
-
0034728128
-
Formation of 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol 4-phosphate by 2-C- methyl-D-erythritol 4-phosphate cytidyl transferase, a new enzyme in the nonmevalonate pathway
-
Kuzuyama T, Takagi M, Kaneda K, Dairi T, Seto H: Formation of 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol 4-phosphate by 2-C- methyl-D-erythritol 4-phosphate cytidyl transferase, a new enzyme in the nonmevalonate pathway. Tetrahedron Lett (2000) 41(5):703-706.
-
(2000)
Tetrahedron Lett
, vol.41
, Issue.5
, pp. 703-706
-
-
Kuzuyama, T.1
Takagi, M.2
Kaneda, K.3
Dairi, T.4
Seto, H.5
-
29
-
-
0034655829
-
Studies on the non-mevalonate pathway: Conversion of 4-(cytidine 5'-diphospho)-2C-methyl-D-erythritol 4-phosphate to its 2-phospho derivative by 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase
-
Kuzuyama T, Takagi M, Kaneda K, Watanabe H, Dairi T, Seto H: Studies on the non-mevalonate pathway: Conversion of 4-(cytidine 5'-diphospho)-2C-methyl-D-erythritol 4-phosphate to its 2-phospho derivative by 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase. Tetrahedron Lett (2000) 41(16):2925-2928.
-
(2000)
Tetrahedron Lett
, vol.41
, Issue.16
, pp. 2925-2928
-
-
Kuzuyama, T.1
Takagi, M.2
Kaneda, K.3
Watanabe, H.4
Dairi, T.5
Seto, H.6
-
30
-
-
0034728844
-
Studies on the nonmevalonate pathway: Formation of 2-C-methyl-D- erythritol 2,4-cyclodiphosphate from 2-phospho-4-(cytidine 5'-diphospho)-2- C-methyl-D-erythritol
-
Takagi M, Kuzuyama T, Kaneda K, Watanabe H, Dairi T, Seto H: Studies on the nonmevalonate pathway: Formation of 2-C-methyl-D- erythritol 2,4-cyclodiphosphate from 2-phospho-4-(cytidine 5'-diphospho)-2- C-methyl-D-erythritol. Tetrahedron Lett (2000) 41(18):3395-3398.
-
(2000)
Tetrahedron Lett
, vol.41
, Issue.18
, pp. 3395-3398
-
-
Takagi, M.1
Kuzuyama, T.2
Kaneda, K.3
Watanabe, H.4
Dairi, T.5
Seto, H.6
-
31
-
-
0001229845
-
Biosynthesis of isoprenoids in Escherichia coli: The fate of the 3-H and 4-H atoms of 1-deoxy-D-xylulose
-
Giner J-L, Jaun B, Arigoni D: Biosynthesis of isoprenoids in Escherichia coli: The fate of the 3-H and 4-H atoms of 1-deoxy-D-xylulose. J Chem Soc Chem Commun (1998):1857-1858.
-
(1998)
J Chem Soc Chem Commun
, pp. 1857-1858
-
-
Giner, J.-L.1
Jaun, B.2
Arigoni, D.3
-
32
-
-
0034653549
-
Deuterium labelled isotopomers of 2-C- methyl-D-erythritol as tools for the elucidation of the 2-C- methyl-D-erythritol 4-phosphate pathway for isoprenoid biosynthesis
-
Charon L, Hoeffler JF, Pale-Grosdemange C, Lois LM, Campos N, Boronat A, Rohmer M: Deuterium labelled isotopomers of 2-C- methyl-D-erythritol as tools for the elucidation of the 2-C- methyl-D-erythritol 4-phosphate pathway for isoprenoid biosynthesis. Biochem J (2000) 346(3):737-742.
-
(2000)
Biochem J
, vol.346
, Issue.3
, pp. 737-742
-
-
Charon, L.1
Hoeffler, J.F.2
Pale-Grosdemange, C.3
Lois, L.M.4
Campos, N.5
Boronat, A.6
Rohmer, M.7
-
33
-
-
0032811818
-
Escherichia coli open reading frame 696 is idi, a nonessential gene encoding isopentenyl diphosphate isomerase
-
Hahn FM, Hurlburt AP, Poulter CD: Escherichia coli open reading frame 696 is idi, a nonessential gene encoding isopentenyl diphosphate isomerase. J Bacteriol (1999) 181(15):4499-4504.
-
(1999)
J Bacteriol
, vol.181
, Issue.15
, pp. 4499-4504
-
-
Hahn, F.M.1
Hurlburt, A.P.2
Poulter, C.D.3
-
34
-
-
0034685844
-
1Genetic evidence of branching in the isoprenoid pathway for the production of isopentenyl diphosphate and dimethylallyl diphosphate in Escherichia coli
-
Rodriguez-Concepción M, Campos M, Lois LM, Maldonado C, Hoeffler JF, Grosdemange-Billiard C, Rohmer M, Boronat A: 1Genetic evidence of branching in the isoprenoid pathway for the production of isopentenyl diphosphate and dimethylallyl diphosphate in Escherichia coli. FEBS Lett (2000) 473(3):328-332.
-
(2000)
FEBS Lett
, vol.473
, Issue.3
, pp. 328-332
-
-
Rodriguez-Concepción, M.1
Campos, M.2
Lois, L.M.3
Maldonado, C.4
Hoeffler, J.F.5
Grosdemange-Billiard, C.6
Rohmer, M.7
Boronat, A.8
-
35
-
-
0035910386
-
Identification of gcpE as a novel gene of the 2-C-methyl-D-erythritol 4-phosphate pathway for isoprenoid biosynthesis in Escherichia coli
-
Campos N, Rodriguez-Concepción M, Seemann M, Rohmer M, Boronat A: Identification of gcpE as a novel gene of the 2-C-methyl-D-erythritol 4-phosphate pathway for isoprenoid biosynthesis in Escherichia coli. FEBS Lett (2001) 488(3):170-173.
-
(2001)
FEBS Lett
, vol.488
, Issue.3
, pp. 170-173
-
-
Campos, N.1
Rodriguez-Concepción, M.2
Seemann, M.3
Rohmer, M.4
Boronat, A.5
-
36
-
-
0035088792
-
GcpE is involved in the 2-C-methyl-D-erythritol 4-phosphate pathway for isoprenoid biosynthesis in Escherichia coli
-
Altincicek B, Kollas AK, Sanderbrand S, Wiesner J, Hintz M, Beck E, Jomaa H: GcpE is involved in the 2-C-methyl-D-erythritol 4-phosphate pathway for isoprenoid biosynthesis in Escherichia coli. J Bacteriol (2001) 183(8):2411-2416.
-
(2001)
J Bacteriol
, vol.183
, Issue.8
, pp. 2411-2416
-
-
Altincicek, B.1
Kollas, A.K.2
Sanderbrand, S.3
Wiesner, J.4
Hintz, M.5
Beck, E.6
Jomaa, H.7
-
37
-
-
0033813444
-
Evidence for a role for LytB in the nonmevalonate pathway of isoprenoid biosynthesis
-
Cunningham FX Jr, Lafond TP, Gantt E: Evidence for a role for LytB in the nonmevalonate pathway of isoprenoid biosynthesis. J Bacteriol (2000) 182(20):5841-5848.
-
(2000)
J Bacteriol
, vol.182
, Issue.20
, pp. 5841-5848
-
-
Cunningham Jr, F.X.1
Lafond, T.P.2
Gantt, E.3
-
38
-
-
0035876043
-
-
Altincicek B, Kollas AK, Eberl M, Wiesner J, Sanderbrand S, Hintz M, Beck E, Jomaa H: LytB, a novel gene of the 2-C-methyl-D- erythritol 4-phosphate pathway of isoprenoid biosynthesis in Escherichia coli. FEBS Lett (2001) 499(1-2):37-40.
-
Altincicek B, Kollas AK, Eberl M, Wiesner J, Sanderbrand S, Hintz M, Beck E, Jomaa H: LytB, a novel gene of the 2-C-methyl-D- erythritol 4-phosphate pathway of isoprenoid biosynthesis in Escherichia coli. FEBS Lett (2001) 499(1-2):37-40.
-
-
-
-
39
-
-
0035909959
-
Studies on the nonmevalonate pathway to terpenes: The role of the GcpE (IspG) protein
-
Hecht S, Eisenreich W, Adam P, Amslinger S, Kis K, Bacher A, Arigoni D, Rohdich F: Studies on the nonmevalonate pathway to terpenes: The role of the GcpE (IspG) protein. Proc Natl Acad Sci USA (2001) 98(26):14837-14842.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.26
, pp. 14837-14842
-
-
Hecht, S.1
Eisenreich, W.2
Adam, P.3
Amslinger, S.4
Kis, K.5
Bacher, A.6
Arigoni, D.7
Rohdich, F.8
-
40
-
-
0036532443
-
Isoprenoid biosynthesis via the methylerythritol phosphate pathway. (E)-4-Hydroxy-3- methylbut-2-enyl diphosphate: Chemical synthesis and formation from methylerythritol cyclodiphosphate by a cell-free system from Escherichia coli
-
Wolff M, Seemann M, Grosdemange-Billiard C, Tritsch D, Campos N, Rodriguez-Concepción M, Boronat A, Rohmer M: Isoprenoid biosynthesis via the methylerythritol phosphate pathway. (E)-4-Hydroxy-3- methylbut-2-enyl diphosphate: Chemical synthesis and formation from methylerythritol cyclodiphosphate by a cell-free system from Escherichia coli. Tetrahedron Lett (2002) 43(14):2555-2559.
-
(2002)
Tetrahedron Lett
, vol.43
, Issue.14
, pp. 2555-2559
-
-
Wolff, M.1
Seemann, M.2
Grosdemange-Billiard, C.3
Tritsch, D.4
Campos, N.5
Rodriguez-Concepción, M.6
Boronat, A.7
Rohmer, M.8
-
41
-
-
2242429820
-
Isoprenoid biosynthesis through the methylerythritol phosphate pathway: The (E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase (GcpE) is a [4Fe-4S] protein
-
Seemann M, Bui BT, Wolf M, Tritsch D, Campos N, Boronat A, Marquet A, Rohmer M: Isoprenoid biosynthesis through the methylerythritol phosphate pathway: The (E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase (GcpE) is a [4Fe-4S] protein. Angew Chem Int Ed (2002) 41(22):4337-4339.
-
(2002)
Angew Chem Int Ed
, vol.41
, Issue.22
, pp. 4337-4339
-
-
Seemann, M.1
Bui, B.T.2
Wolf, M.3
Tritsch, D.4
Campos, N.5
Boronat, A.6
Marquet, A.7
Rohmer, M.8
-
42
-
-
0037132506
-
Functional characterization of GcpE, an essential enzyme of the non-mevalonate pathway of isoprenoid biosynthesis
-
Kollas AK, Duin EC, Eberl M, Altincicek B, Hintz M, Reichenberg A, Henschker D, Henne A, Steinbrecher I, Ostrovsky DN, Hedderich R et al: Functional characterization of GcpE, an essential enzyme of the non-mevalonate pathway of isoprenoid biosynthesis. FEBS Lett (2002) 532(3):432-436.
-
(2002)
FEBS Lett
, vol.532
, Issue.3
, pp. 432-436
-
-
Kollas, A.K.1
Duin, E.C.2
Eberl, M.3
Altincicek, B.4
Hintz, M.5
Reichenberg, A.6
Henschker, D.7
Henne, A.8
Steinbrecher, I.9
Ostrovsky, D.N.10
Hedderich, R.11
-
43
-
-
0037022221
-
-
Rohdich F, Hecht S, Gärtner K, Adam P, Krieger C, Amslinger S, Arigoni D, Bacher A, Eisenreich W: Studies on the nonmevalonate terpene biosynthetic pathway: Metabolic role of IspH (LytB) protein. Proc Natl Acad Sci USA (2002) 99Q(3):1158-1163.
-
Rohdich F, Hecht S, Gärtner K, Adam P, Krieger C, Amslinger S, Arigoni D, Bacher A, Eisenreich W: Studies on the nonmevalonate terpene biosynthetic pathway: Metabolic role of IspH (LytB) protein. Proc Natl Acad Sci USA (2002) 99Q(3):1158-1163.
-
-
-
-
44
-
-
0037126065
-
Biosynthesis of terpenes: Studies on 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase
-
Adam P, Hecht S, Eisenreich W, Kaiser J, Gräwert T, Arigoni D, Bacher A, Rohdich F: Biosynthesis of terpenes: Studies on 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase. Proc Natl Acad Sci USA (2002) 99(19):12108-12119.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.19
, pp. 12108-12119
-
-
Adam, P.1
Hecht, S.2
Eisenreich, W.3
Kaiser, J.4
Gräwert, T.5
Arigoni, D.6
Bacher, A.7
Rohdich, F.8
-
45
-
-
0037132556
-
LytB protein catalyzes the terminal step of the 2-C-methyl-D-erythritol-4-phosphate pathway for isoprenoid biosynthesis
-
Altincicek B, Duin EC, Reichenberg A, Hedderich R, Kollas AC, Hintz M, Wagner S, Wiesner J, Beck E, Jomaa H: LytB protein catalyzes the terminal step of the 2-C-methyl-D-erythritol-4-phosphate pathway for isoprenoid biosynthesis. FEBS Lett (2002) 532(3):437-440.
-
(2002)
FEBS Lett
, vol.532
, Issue.3
, pp. 437-440
-
-
Altincicek, B.1
Duin, E.C.2
Reichenberg, A.3
Hedderich, R.4
Kollas, A.C.5
Hintz, M.6
Wagner, S.7
Wiesner, J.8
Beck, E.9
Jomaa, H.10
-
46
-
-
0037452578
-
The deoxyxylulose phosphate pathway of isoprenoid biosynthesis: Studies on the mechanisms of the reaction catalyzed by IspG and IspH proteins
-
Rohdich F, Zepeck F, Adam P, Hecht S, Kaiser J, Laupitz R, Gräwert T, Amslinger S, Eisenreich W, Bacher A, Arigoni D: The deoxyxylulose phosphate pathway of isoprenoid biosynthesis: Studies on the mechanisms of the reaction catalyzed by IspG and IspH proteins. Proc Natl Acad Sci USA (2003) 100(4):1586-1591.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.4
, pp. 1586-1591
-
-
Rohdich, F.1
Zepeck, F.2
Adam, P.3
Hecht, S.4
Kaiser, J.5
Laupitz, R.6
Gräwert, T.7
Amslinger, S.8
Eisenreich, W.9
Bacher, A.10
Arigoni, D.11
-
47
-
-
0037464490
-
-
Wolff M, Seemann M, Tse Sum Bui B, Frapart Y, Tritsch D, Estrabot AG, Rodriguez-Concepción M, Boronat A, Marquet A, Rohmer M: Isoprenoid biosynthesis via the methylerythritol phosphate pathway: The (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase (LytB/IspH) from Escherichia coli is a [4Fe-4S] protein. FEBS Lett (2003) 541 (1-3): 115-120.
-
Wolff M, Seemann M, Tse Sum Bui B, Frapart Y, Tritsch D, Estrabot AG, Rodriguez-Concepción M, Boronat A, Marquet A, Rohmer M: Isoprenoid biosynthesis via the methylerythritol phosphate pathway: The (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase (LytB/IspH) from Escherichia coli is a [4Fe-4S] protein. FEBS Lett (2003) 541 (1-3): 115-120.
-
-
-
-
48
-
-
0033859551
-
The role of lateral gene transfer in the evolution of isoprenoid biosynthesis pathways
-
Boucher Y, Doolittle WF: The role of lateral gene transfer in the evolution of isoprenoid biosynthesis pathways. Mol Microbiol (2000) 37(4):703-716.
-
(2000)
Mol Microbiol
, vol.37
, Issue.4
, pp. 703-716
-
-
Boucher, Y.1
Doolittle, W.F.2
-
49
-
-
0034700150
-
Isoprenoid biosynthesis: The evolution of two ancient and distinct pathways across genomes
-
Lange BM, Rujan T, Martin W, Croteau R: Isoprenoid biosynthesis: The evolution of two ancient and distinct pathways across genomes. Proc Natl Acad Sci USA (2000) 97(24):13172-13177.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.24
, pp. 13172-13177
-
-
Lange, B.M.1
Rujan, T.2
Martin, W.3
Croteau, R.4
-
50
-
-
0038695014
-
Microbial isoprenoid biosynthesis and human γδ T cell activation
-
Eberl M, Hintz M, Reichenberg A, Kollas AK, Wiesner J, Jomaa H: Microbial isoprenoid biosynthesis and human γδ T cell activation. FEBS Lett (2003) 544(1-3):4-10.
-
(2003)
FEBS Lett
, vol.544
, Issue.1-3
, pp. 4-10
-
-
Eberl, M.1
Hintz, M.2
Reichenberg, A.3
Kollas, A.K.4
Wiesner, J.5
Jomaa, H.6
-
51
-
-
0030605182
-
Simultaneous operation of the mevalonate and non-mevalonate pathways in the biosynthesis of isopentenyl diphosphate in Streptomyces aeriouvifer
-
Seto H, Watanabe H, Furihata K: Simultaneous operation of the mevalonate and non-mevalonate pathways in the biosynthesis of isopentenyl diphosphate in Streptomyces aeriouvifer. Tetrahedron Lett (1996) 37(44):7979-7982.
-
(1996)
Tetrahedron Lett
, vol.37
, Issue.44
, pp. 7979-7982
-
-
Seto, H.1
Watanabe, H.2
Furihata, K.3
-
52
-
-
0033520336
-
Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs
-
Jomaa H, Wesner J, Sanderbrand S, Altincicek B, Weidemeyer C, Hintz M, Türbachova I, Eberl M, Zeidler M, Lichtenthaler HK, Soldati D et al: Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs. Science (1999) 285(5433):1573-1576.
-
(1999)
Science
, vol.285
, Issue.5433
, pp. 1573-1576
-
-
Jomaa, H.1
Wesner, J.2
Sanderbrand, S.3
Altincicek, B.4
Weidemeyer, C.5
Hintz, M.6
Türbachova, I.7
Eberl, M.8
Zeidler, M.9
Lichtenthaler, H.K.10
Soldati, D.11
-
53
-
-
0034612219
-
Biosynthesis of terpenoids: 4-Diphosphocytidyl-2C-methyl-D- erythritol synthase of Arabidopsis thaliana
-
Rohdich F, Wungsintaweekul J, Eisenreich W, Richter G, Schuhr CA, Hecht S, Zenk MH, Bacher A: Biosynthesis of terpenoids: 4-Diphosphocytidyl-2C-methyl-D- erythritol synthase of Arabidopsis thaliana. Proc Natl Acad Sci USA (2000) 97(12):6451-6456.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.12
, pp. 6451-6456
-
-
Rohdich, F.1
Wungsintaweekul, J.2
Eisenreich, W.3
Richter, G.4
Schuhr, C.A.5
Hecht, S.6
Zenk, M.H.7
Bacher, A.8
-
54
-
-
0034845931
-
Biosynthesis of terpenoids. 2C-Methyl-D-erythritol 2,4-cyclodiphosphate synthase (IspF) from Plasmodium falciparum
-
Rohdich F, Eisenreich W, Wungsintaweekul J, Hecht S, Schuhr CA, Bacher A: Biosynthesis of terpenoids. 2C-Methyl-D-erythritol 2,4-cyclodiphosphate synthase (IspF) from Plasmodium falciparum. Eur J Biochem (2001) 268(11):3190-3197.
-
(2001)
Eur J Biochem
, vol.268
, Issue.11
, pp. 3190-3197
-
-
Rohdich, F.1
Eisenreich, W.2
Wungsintaweekul, J.3
Hecht, S.4
Schuhr, C.A.5
Bacher, A.6
-
55
-
-
0035941120
-
Essential role of residue H49 for activity of Escherichia coli 1-deoxy-D-xylulose 5-phosphate synthase, the enzyme catalyzing the first step of the 2-C- methyl-D-erythritol 4-phosphate pathway for isoprenoid synthesis
-
Querol J, Rodriguez-Concepcion M, Boronat A, Imperial S: Essential role of residue H49 for activity of Escherichia coli 1-deoxy-D-xylulose 5-phosphate synthase, the enzyme catalyzing the first step of the 2-C- methyl-D-erythritol 4-phosphate pathway for isoprenoid synthesis. Biochem Biophys Res Commun (2001) 289(1):155-160.
-
(2001)
Biochem Biophys Res Commun
, vol.289
, Issue.1
, pp. 155-160
-
-
Querol, J.1
Rodriguez-Concepcion, M.2
Boronat, A.3
Imperial, S.4
-
56
-
-
0034733529
-
Characterization of 1-deoxy-D-xylulose 5-phosphate reductoisomerase, an enzyme involved in isopentenyl diphosphate biosynthesis, and identification of its catalytic amino acid residues
-
Kuzuyama T, Takahashi S, Takagi M, Seto H: Characterization of 1-deoxy-D-xylulose 5-phosphate reductoisomerase, an enzyme involved in isopentenyl diphosphate biosynthesis, and identification of its catalytic amino acid residues. J Biol Chem (2000) 275(26):19928-19932.
-
(2000)
J Biol Chem
, vol.275
, Issue.26
, pp. 19928-19932
-
-
Kuzuyama, T.1
Takahashi, S.2
Takagi, M.3
Seto, H.4
-
57
-
-
0036213823
-
Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase complexed with cofactors: Implications of a flexible loop movement upon substrate binding
-
Yajima S, Nonaka T, Kuzuyama T, Seto H, Ohsawa K: Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase complexed with cofactors: Implications of a flexible loop movement upon substrate binding. J Biochem (2002) 131(3):313-317.
-
(2002)
J Biochem
, vol.131
, Issue.3
, pp. 313-317
-
-
Yajima, S.1
Nonaka, T.2
Kuzuyama, T.3
Seto, H.4
Ohsawa, K.5
-
58
-
-
0037085356
-
Crystal structure of 1-deoxy-D-xylulose-5- phosphate reductoisomerase, a crucial enzyme in the non-mevalonate pathway for isoprenoid biosynthesis
-
Reuter K, Sanderbrand S, Jomaa H, Wiesner J, Steinbrecher I, Beck E, Hintz M, Klebe G, Stubbs MT: Crystal structure of 1-deoxy-D-xylulose-5- phosphate reductoisomerase, a crucial enzyme in the non-mevalonate pathway for isoprenoid biosynthesis. J Biol Chem (2002) 277(7):5378-5384.
-
(2002)
J Biol Chem
, vol.277
, Issue.7
, pp. 5378-5384
-
-
Reuter, K.1
Sanderbrand, S.2
Jomaa, H.3
Wiesner, J.4
Steinbrecher, I.5
Beck, E.6
Hintz, M.7
Klebe, G.8
Stubbs, M.T.9
-
59
-
-
0034953307
-
Structure of 4-diphosphocytidyl-2-C- methylerythritol synthetase involved in mevalonate-independent isoprenoid biosynthesis
-
Richard SB, Bowman ME, Kwiatkowski W, Kang I, Chow C, Lillo AM, Cane DE, Noel JP: Structure of 4-diphosphocytidyl-2-C- methylerythritol synthetase involved in mevalonate-independent isoprenoid biosynthesis. Nat Struct Biol (2001) 8(7):641-648.
-
(2001)
Nat Struct Biol
, vol.8
, Issue.7
, pp. 641-648
-
-
Richard, S.B.1
Bowman, M.E.2
Kwiatkowski, W.3
Kang, I.4
Chow, C.5
Lillo, A.M.6
Cane, D.E.7
Noel, J.P.8
-
60
-
-
0034909321
-
Crystallization and preliminary x-ray diffraction studies of recombinant Escherichia coli 4-diphosphocytidyl-2-C-methyl-D-erythritol synthetase
-
Kemp LE, Bond CS, Hunter WN: Crystallization and preliminary x-ray diffraction studies of recombinant Escherichia coli 4-diphosphocytidyl-2-C-methyl-D-erythritol synthetase. Acta Crystallogr D Biol Crystallogr (2001) 57(8):1189-1191.
-
(2001)
Acta Crystallogr D Biol Crystallogr
, vol.57
, Issue.8
, pp. 1189-1191
-
-
Kemp, L.E.1
Bond, C.S.2
Hunter, W.N.3
-
61
-
-
0042424807
-
Biosynthesis of isoprenoids: Crystal structure of 4-diphosphocytidyl-2C-methyl-D-erythritol kinase
-
Miallau L, Alphey MS, Kemp LE, Leonard GA, McSweeney SM, Hecht S, Bacher A, Eisenreich W, Rohdich F, Hunter WN: Biosynthesis of isoprenoids: Crystal structure of 4-diphosphocytidyl-2C-methyl-D-erythritol kinase. Proc Natl Acad Sci USA (2003) 100(16):9173-9178.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.16
, pp. 9173-9178
-
-
Miallau, L.1
Alphey, M.S.2
Kemp, L.E.3
Leonard, G.A.4
McSweeney, S.M.5
Hecht, S.6
Bacher, A.7
Eisenreich, W.8
Rohdich, F.9
Hunter, W.N.10
-
62
-
-
0042030862
-
Crystal structure of 4-(cytidine 5'-diphospho)-2-C-methyl-D- erythritol kinase, an enzyme in the non-mevalonate pathway for isoprenoid biosynthesis
-
Wada T, Kuzuyama T, Satoh S, Kuramitsu S, Yokoyama S, Unzai S, Tame JR, Park SY: Crystal structure of 4-(cytidine 5'-diphospho)-2-C-methyl-D- erythritol kinase, an enzyme in the non-mevalonate pathway for isoprenoid biosynthesis. J Biol Chem (2003) 278(32):30022-30027.
-
(2003)
J Biol Chem
, vol.278
, Issue.32
, pp. 30022-30027
-
-
Wada, T.1
Kuzuyama, T.2
Satoh, S.3
Kuramitsu, S.4
Yokoyama, S.5
Unzai, S.6
Tame, J.R.7
Park, S.Y.8
-
63
-
-
0037040915
-
Structure and mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. An enzyme in the mevalonate-independent isoprenoid biosynthetic pathway
-
Richard SB, Ferrer JL, Bowman ME, Lillo AM, Tetzlaff CN, Cane DE, Noel JP: Structure and mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. An enzyme in the mevalonate-independent isoprenoid biosynthetic pathway. J Biol Chem (2002) 277(10):8667-8672.
-
(2002)
J Biol Chem
, vol.277
, Issue.10
, pp. 8667-8672
-
-
Richard, S.B.1
Ferrer, J.L.2
Bowman, M.E.3
Lillo, A.M.4
Tetzlaff, C.N.5
Cane, D.E.6
Noel, J.P.7
-
64
-
-
0036304411
-
Structure of 2C-methyl-D- erythritol-2,4-cyclodiphosphate synthase involved in mevalonate-independent biosynthesis of isoprenoids
-
Steinbacher S, Kaiser J, Wungsintaweekul J, Hecht S, Eisenreich W, Gerhardt S, Bacher A, Rohdich F: Structure of 2C-methyl-D- erythritol-2,4-cyclodiphosphate synthase involved in mevalonate-independent biosynthesis of isoprenoids. J Mol Biol (2002) 316(1):79-88.
-
(2002)
J Mol Biol
, vol.316
, Issue.1
, pp. 79-88
-
-
Steinbacher, S.1
Kaiser, J.2
Wungsintaweekul, J.3
Hecht, S.4
Eisenreich, W.5
Gerhardt, S.6
Bacher, A.7
Rohdich, F.8
-
65
-
-
0037076321
-
Structure of 2C-methyl-D- erythritol 2,4-cyclodiphosphate synthase: An essential enzyme for isoprenoid biosynthesis and target for antimicrobial drug development
-
Kemp LE, Bond CS, Hunter WN: Structure of 2C-methyl-D- erythritol 2,4-cyclodiphosphate synthase: An essential enzyme for isoprenoid biosynthesis and target for antimicrobial drug development. Proc Natl Acad Sci USA (2002) 99(10):6591-6596.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.10
, pp. 6591-6596
-
-
Kemp, L.E.1
Bond, C.S.2
Hunter, W.N.3
-
66
-
-
0037238125
-
Structure and catalytic mechanisms of 2-C-methyl-D-erythritol cyclodiphosphate (MECDP) synthase, an enzyme in the non-mevalonate pathway for isoprenoid biosynthesis
-
Kishida H, Unzai S, Kuzuyama T, Takagi M, Terada T, Shirouzu M, Yokoyama S, Tame JRH, Park SY: Structure and catalytic mechanisms of 2-C-methyl-D-erythritol cyclodiphosphate (MECDP) synthase, an enzyme in the non-mevalonate pathway for isoprenoid biosynthesis. Acta Cryst (2003) D59:23-31.
-
(2003)
Acta Cryst
, vol.D59
, pp. 23-31
-
-
Kishida, H.1
Unzai, S.2
Kuzuyama, T.3
Takagi, M.4
Terada, T.5
Shirouzu, M.6
Yokoyama, S.7
Tame, J.R.H.8
Park, S.Y.9
-
67
-
-
0019252768
-
Studies on new phosphonic acid antibiotics. III. Isolation and characterization of FR-31564, FR-32863 and FR-33289
-
Okuhara M, Kuroda Y, Goto T, Okamoto M, Terano H, Kohsaka M, Aoki H, Imanaka H: Studies on new phosphonic acid antibiotics. III. Isolation and characterization of FR-31564, FR-32863 and FR-33289. J Antibiot (1980) 33(1):24-28.
-
(1980)
J Antibiot
, vol.33
, Issue.1
, pp. 24-28
-
-
Okuhara, M.1
Kuroda, Y.2
Goto, T.3
Okamoto, M.4
Terano, H.5
Kohsaka, M.6
Aoki, H.7
Imanaka, H.8
-
68
-
-
0019256502
-
In vitro and in vivo antibacterial activities of FR-31564, a new phosphonic acid antibiotic
-
Mine Y, Kamimura M, Nonoyama S, Nishida M, Goto S, Kuwahara S: In vitro and in vivo antibacterial activities of FR-31564, a new phosphonic acid antibiotic. J Antibiot (1980) 33(1):36-43.
-
(1980)
J Antibiot
, vol.33
, Issue.1
, pp. 36-43
-
-
Mine, Y.1
Kamimura, M.2
Nonoyama, S.3
Nishida, M.4
Goto, S.5
Kuwahara, S.6
-
69
-
-
0024421915
-
Inhibition of bacterial isoprenoid synthesis by fosmidomycin, a phosphonic acid-containing antibiotic
-
Shigi Y: Inhibition of bacterial isoprenoid synthesis by fosmidomycin, a phosphonic acid-containing antibiotic. J Antimicrob Chemother (1989) 24(2):131-145.
-
(1989)
J Antimicrob Chemother
, vol.24
, Issue.2
, pp. 131-145
-
-
Shigi, Y.1
-
70
-
-
0032558613
-
Fosmidomycin, a specific inhibitor of 1-deoxy-D-xylulose 5-phosphate reductoisomerase in the nonmevalonate pathway for terpenoid biosynthesis
-
Kuzuyama T, Shimizu T, Takahashi S, Seto H: Fosmidomycin, a specific inhibitor of 1-deoxy-D-xylulose 5-phosphate reductoisomerase in the nonmevalonate pathway for terpenoid biosynthesis. Tetrahedron Lett (1998) 39(43):7913-7916.
-
(1998)
Tetrahedron Lett
, vol.39
, Issue.43
, pp. 7913-7916
-
-
Kuzuyama, T.1
Shimizu, T.2
Takahashi, S.3
Seto, H.4
-
71
-
-
0034308011
-
-
Grolle S, Bringer-Meyer S, Sahm H: Isolation of the dxr gene of Zymomonas mobilis and characterization of the 1-deoxy-D-xylulose 5-phosphate reductoisomerase. FEMS Microbiol Lett (2000) 191(1):131-137.
-
Grolle S, Bringer-Meyer S, Sahm H: Isolation of the dxr gene of Zymomonas mobilis and characterization of the 1-deoxy-D-xylulose 5-phosphate reductoisomerase. FEMS Microbiol Lett (2000) 191(1):131-137.
-
-
-
-
72
-
-
0032439587
-
Inhibition of the non-mevalonate 1-deoxy-D-xylulose-5-phosphate pathway of plant isoprenoid biosynthesis by fosmidomycin
-
Zeidler JG, Schwender J, Müller C, Wiesner J, Weidemeyer C, Beck E, Jomaa H, Lichtenthaler HK: Inhibition of the non-mevalonate 1-deoxy-D-xylulose-5-phosphate pathway of plant isoprenoid biosynthesis by fosmidomycin. Z Naturforsch (1998) 53C:980-986.
-
(1998)
Z Naturforsch
, vol.53 C
, pp. 980-986
-
-
Zeidler, J.G.1
Schwender, J.2
Müller, C.3
Wiesner, J.4
Weidemeyer, C.5
Beck, E.6
Jomaa, H.7
Lichtenthaler, H.K.8
-
73
-
-
0033515735
-
-
Fellermeier M, Kis K, Sagner S, Maier U, Bacher A, Zenk MH: Cell-free conversion of 1-deoxy-D-xylulose 5-phosphate and 2-C-methyl-D- erythritol 4-phosphate into β-carotene in higher plants and its inhibition by fosmidomycin. Tetrahedron Lett1 (1999) 40(14):2743-2746.
-
Fellermeier M, Kis K, Sagner S, Maier U, Bacher A, Zenk MH: Cell-free conversion of 1-deoxy-D-xylulose 5-phosphate and 2-C-methyl-D- erythritol 4-phosphate into β-carotene in higher plants and its inhibition by fosmidomycin. Tetrahedron Lett1 (1999) 40(14):2743-2746.
-
-
-
-
74
-
-
0035953022
-
Diaryl ester prodrugs of FR90008 with improved in vivo antimalarial activity
-
Reichenberg A, Wiesner J, Weidemeyer C, Dreiseidler E, Sanderbrand S, Altincicek B, Beck E, Schlitzer M, Jomaa H: Diaryl ester prodrugs of FR90008 with improved in vivo antimalarial activity. Bioorg Med Chem Lett (2001) 11(6):833-835.
-
(2001)
Bioorg Med Chem Lett
, vol.11
, Issue.6
, pp. 833-835
-
-
Reichenberg, A.1
Wiesner, J.2
Weidemeyer, C.3
Dreiseidler, E.4
Sanderbrand, S.5
Altincicek, B.6
Beck, E.7
Schlitzer, M.8
Jomaa, H.9
-
75
-
-
0035789749
-
DFT study of a substrate and inhibitors of 1-deoxy-2-xylulose-5-phosphate reductoisomerase - the potential novel target molecule for anti-malaria drug development
-
Zubrzycki IZ, Blatch GL: DFT study of a substrate and inhibitors of 1-deoxy-2-xylulose-5-phosphate reductoisomerase - the potential novel target molecule for anti-malaria drug development. J Mol Model (2001) 7(10):378-383.
-
(2001)
J Mol Model
, vol.7
, Issue.10
, pp. 378-383
-
-
Zubrzycki, I.Z.1
Blatch, G.L.2
-
76
-
-
0038043258
-
Structural basis of fosmidomycin action revealed by the complex with 2-C-methyl-D-erythritol synthase (IspC). Implications for the catalytic mechanism and anti-malaria drug development
-
Steinbacher S, Kaiser J, Eisenreich W, Huber R, Bacher A, Rohdich F: Structural basis of fosmidomycin action revealed by the complex with 2-C-methyl-D-erythritol synthase (IspC). Implications for the catalytic mechanism and anti-malaria drug development. J Biol Chem (2003) 278(20):18401-18407.
-
(2003)
J Biol Chem
, vol.278
, Issue.20
, pp. 18401-18407
-
-
Steinbacher, S.1
Kaiser, J.2
Eisenreich, W.3
Huber, R.4
Bacher, A.5
Rohdich, F.6
-
77
-
-
2842613801
-
Fosmidimycin resistance in adenylate cyclase (cya) mutants of Escherichia coli
-
Sakamoto Y, Furukawa S, Ogihara H, Yamasaki M: Fosmidimycin resistance in adenylate cyclase (cya) mutants of Escherichia coli. Biosci Biotechnol Biochem (2003) 67(9):2030-2033.
-
(2003)
Biosci Biotechnol Biochem
, vol.67
, Issue.9
, pp. 2030-2033
-
-
Sakamoto, Y.1
Furukawa, S.2
Ogihara, H.3
Yamasaki, M.4
-
78
-
-
0034666627
-
Tools for discovery of the 1-deoxy-D-xylulose 5-phosphate (DXP) synthase and DXP reductoisomerase: An approach with enzymes from the pathogenic bacterium Pseudomonas aeruginosa
-
Altincicek B, Hintz M, Sanderbrand S, Wiesner J, Beck E, Jomaa H: Tools for discovery of the 1-deoxy-D-xylulose 5-phosphate (DXP) synthase and DXP reductoisomerase: An approach with enzymes from the pathogenic bacterium Pseudomonas aeruginosa. FEMS Microbiol Lett (2000) 190(2):329-333.
-
(2000)
FEMS Microbiol Lett
, vol.190
, Issue.2
, pp. 329-333
-
-
Altincicek, B.1
Hintz, M.2
Sanderbrand, S.3
Wiesner, J.4
Beck, E.5
Jomaa, H.6
-
79
-
-
0034472991
-
Properties and inhibition of the first two enzymes of the non-mevalonate pathway of isoprenoid biosynthesis
-
Mueller C, Schwender J, Zeidler J, Lichtenthaler HK: Properties and inhibition of the first two enzymes of the non-mevalonate pathway of isoprenoid biosynthesis. Biochem Soc Trans (2000) 28(6):792-793.
-
(2000)
Biochem Soc Trans
, vol.28
, Issue.6
, pp. 792-793
-
-
Mueller, C.1
Schwender, J.2
Zeidler, J.3
Lichtenthaler, H.K.4
-
80
-
-
0034832084
-
Phosphorylation of 1-deoxy-D-xylulose by D-xylulokinase of Escherichia coli
-
Wungsintaweekul J, Herz S, Hecht S, Eisenreich W, Feicht R, Rohdich F, Bacher A, Zenk MH: Phosphorylation of 1-deoxy-D-xylulose by D-xylulokinase of Escherichia coli. Eur J Biochem (2001) 268(2):310-316.
-
(2001)
Eur J Biochem
, vol.268
, Issue.2
, pp. 310-316
-
-
Wungsintaweekul, J.1
Herz, S.2
Hecht, S.3
Eisenreich, W.4
Feicht, R.5
Rohdich, F.6
Bacher, A.7
Zenk, M.H.8
-
81
-
-
0033588318
-
The synthesis of 1-fluoro- and 1,1-difluoro-analogues of 1-deoxy-D-xylulose
-
Bouvet D, O'Hagan D: The synthesis of 1-fluoro- and 1,1-difluoro-analogues of 1-deoxy-D-xylulose. Tetrahedron (1999) 55(34):10481-10486.
-
(1999)
Tetrahedron
, vol.55
, Issue.34
, pp. 10481-10486
-
-
Bouvet, D.1
O'Hagan, D.2
-
82
-
-
0027054736
-
The ability of bacteria to synthesize a new cyclopyrophosphate correlates with their tolerance to redox-cycling drugs: On a crossroad of chemotherapy, environmental toxicology and immunobiochemical problems
-
Ostrovsky D, Kharatian E, Dubrovsky T, Ogrel O, Shipanova I, Sibeldina L: The ability of bacteria to synthesize a new cyclopyrophosphate correlates with their tolerance to redox-cycling drugs: On a crossroad of chemotherapy, environmental toxicology and immunobiochemical problems. Biofactors (1992) 4(1):63-68.
-
(1992)
Biofactors
, vol.4
, Issue.1
, pp. 63-68
-
-
Ostrovsky, D.1
Kharatian, E.2
Dubrovsky, T.3
Ogrel, O.4
Shipanova, I.5
Sibeldina, L.6
-
83
-
-
0026582685
-
Synthesis of a new organic pyrophosphate in large quantities is induced in some bacteria by oxidative stress
-
Ostrovsky D, Kharatian E, Malarova I, Shipanova I, Sibeldina L, Shashkov A, Tantsirev G: Synthesis of a new organic pyrophosphate in large quantities is induced in some bacteria by oxidative stress. Biofactors (1992) 3(4):261-264.
-
(1992)
Biofactors
, vol.3
, Issue.4
, pp. 261-264
-
-
Ostrovsky, D.1
Kharatian, E.2
Malarova, I.3
Shipanova, I.4
Sibeldina, L.5
Shashkov, A.6
Tantsirev, G.7
-
84
-
-
0032462288
-
Effect of oxidative stress on the biosynthesis of 2-C-methyl-D- erythritol-2,4-cyclopyrophosphate and isoprenoids by several bacterial strains
-
Ostrovsky D, Diomina G, Lysak E, Matveeva E, Ogrel O, Trutko S:Effect of oxidative stress on the biosynthesis of 2-C-methyl-D- erythritol-2,4-cyclopyrophosphate and isoprenoids by several bacterial strains. Arch Microbiol (1998) 171(1):69-72.
-
(1998)
Arch Microbiol
, vol.171
, Issue.1
, pp. 69-72
-
-
Ostrovsky, D.1
Diomina, G.2
Lysak, E.3
Matveeva, E.4
Ogrel, O.5
Trutko, S.6
-
85
-
-
0035970116
-
An unusual isopentenyl diphosphate isomerase found in the mevalonate pathway gene cluster from Streptomyces sp strain CL190
-
Kaneda K, Kuzuyama T, Takagi M, Hayakawa Y, Seto H: An unusual isopentenyl diphosphate isomerase found in the mevalonate pathway gene cluster from Streptomyces sp strain CL190. Proc Natl Acad Sci USA (2001) 98(3):932-937.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.3
, pp. 932-937
-
-
Kaneda, K.1
Kuzuyama, T.2
Takagi, M.3
Hayakawa, Y.4
Seto, H.5
-
86
-
-
0031864162
-
Isoprenoid biosynthesis via the mevalonate-independent route, a novel target for antibacterial drugs?
-
Rohmer M: Isoprenoid biosynthesis via the mevalonate-independent route, a novel target for antibacterial drugs? Prog Drug Res (1998) 50:134-154.
-
(1998)
Prog Drug Res
, vol.50
, pp. 134-154
-
-
Rohmer, M.1
-
87
-
-
0030579174
-
Cloning of a gene from Escherichia coli that confers resistance to fosmidomycin as a consequence of amplification
-
Fujisaki S, Ohnuma SI, Horiuchi T, Takahashi I, Tsukui S, Nishimura Y, Nishino T, Kitabatake M, Inokuchi H: Cloning of a gene from Escherichia coli that confers resistance to fosmidomycin as a consequence of amplification. Gene (1996) 175(1-2):83-87.
-
(1996)
Gene
, vol.175
, Issue.1-2
, pp. 83-87
-
-
Fujisaki, S.1
Ohnuma, S.I.2
Horiuchi, T.3
Takahashi, I.4
Tsukui, S.5
Nishimura, Y.6
Nishino, T.7
Kitabatake, M.8
Inokuchi, H.9
-
88
-
-
0037079323
-
Fosmidomycin for malaria
-
Missinou MA, Borrmann S, Schindler A, Issifou S, Adegnika AA, Matsiegui PB, Binder R, Lell B, Wiesner J, Baranek T, Jomaa H et al: Fosmidomycin for malaria. Lancet (2002) 360(9349):1941-1942
-
(2002)
Lancet
, vol.360
, Issue.9349
, pp. 1941-1942
-
-
Missinou, M.A.1
Borrmann, S.2
Schindler, A.3
Issifou, S.4
Adegnika, A.A.5
Matsiegui, P.B.6
Binder, R.7
Lell, B.8
Wiesner, J.9
Baranek, T.10
Jomaa, H.11
-
89
-
-
0021932270
-
Fosmidomycin, a new phosphonic acid antibiotic. Part II: 1. Human pharmacokinetics. 2. Preliminary early phase IIa clinical studies
-
Kuemmerle HP, Murakawa T, Sakamoto H, Sato N, Konishi T, De Santis F: Fosmidomycin, a new phosphonic acid antibiotic. Part II: 1. Human pharmacokinetics. 2. Preliminary early phase IIa clinical studies. Int J Clin Pharmacol Ther Toxicol (1985) 23(10):521-528.
-
(1985)
Int J Clin Pharmacol Ther Toxicol
, vol.23
, Issue.10
, pp. 521-528
-
-
Kuemmerle, H.P.1
Murakawa, T.2
Sakamoto, H.3
Sato, N.4
Konishi, T.5
De Santis, F.6
-
90
-
-
0000725115
-
Distribution of mevalonate and glyceraldehyde 3-phosphate/pyruvate routes for isoprenoid biosynthesis in some Gram-negative bacteria and mycobacteria
-
Rosa-Putra S, Disch A, Bravo JM, Rohmer M: Distribution of mevalonate and glyceraldehyde 3-phosphate/pyruvate routes for isoprenoid biosynthesis in some Gram-negative bacteria and mycobacteria. FEMS Microbiol Lett (1998) 164(1):169-175.
-
(1998)
FEMS Microbiol Lett
, vol.164
, Issue.1
, pp. 169-175
-
-
Rosa-Putra, S.1
Disch, A.2
Bravo, J.M.3
Rohmer, M.4
-
91
-
-
0033522836
-
Biosynthesis of diterpenoid moiety of brasilicardin A via non-mevalonate pathway in Nocardia brasiliensis
-
Shigemori H, Komaki H, Yazawa K, Mikami Y, Nemoto A, Tanaka Y, Kobayashi J: Biosynthesis of diterpenoid moiety of brasilicardin A via non-mevalonate pathway in Nocardia brasiliensis. Tetrahedron Lett (1999) 40(23):4353-4354.
-
(1999)
Tetrahedron Lett
, vol.40
, Issue.23
, pp. 4353-4354
-
-
Shigemori, H.1
Komaki, H.2
Yazawa, K.3
Mikami, Y.4
Nemoto, A.5
Tanaka, Y.6
Kobayashi, J.7
-
92
-
-
0035856580
-
Zeaxanthin and menaquinone-7 biosynthesis in Sphingobacterium multivorum via the methylerythritol phosphate pathway
-
Rosa-Putra S, Hemmerlin A, Epperson J, Bach TJ, Guerra LH, Rohmer M: Zeaxanthin and menaquinone-7 biosynthesis in Sphingobacterium multivorum via the methylerythritol phosphate pathway. FEMS Microbiol Lett (2001) 204(2):347-353.
-
(2001)
FEMS Microbiol Lett
, vol.204
, Issue.2
, pp. 347-353
-
-
Rosa-Putra, S.1
Hemmerlin, A.2
Epperson, J.3
Bach, T.J.4
Guerra, L.H.5
Rohmer, M.6
-
93
-
-
0035823183
-
Evidence for the biosynthesis of squalene via the methylerythritol phosphate pathway in a Streptomyces sp obtained from a marine sediment
-
Fontana A, Kelly MT, Prasad JD, Andersen RJ: Evidence for the biosynthesis of squalene via the methylerythritol phosphate pathway in a Streptomyces sp obtained from a marine sediment. J Org Chem (2001) 66(18):6202-6206.
-
(2001)
J Org Chem
, vol.66
, Issue.18
, pp. 6202-6206
-
-
Fontana, A.1
Kelly, M.T.2
Prasad, J.D.3
Andersen, R.J.4
-
95
-
-
0036900003
-
-
5]-mevalolactone to a geosmin-producing Streptomyces sp and Fossombronia pusilla. Phytochemistry (2002) 61(7):827-834.
-
5]-mevalolactone to a geosmin-producing Streptomyces sp and Fossombronia pusilla. Phytochemistry (2002) 61(7):827-834.
-
-
-
-
97
-
-
0035237718
-
Identification of a gene cluster for the mevalonate pathway in Lactobacillus helveticus
-
Smeds A, Joutsjoki T, Patva A: Identification of a gene cluster for the mevalonate pathway in Lactobacillus helveticus. DNA Sequence (2001) 12(3):187-190.
-
(2001)
DNA Sequence
, vol.12
, Issue.3
, pp. 187-190
-
-
Smeds, A.1
Joutsjoki, T.2
Patva, A.3
-
98
-
-
0020512161
-
Steroids from the myxobacterium Nannocystis exedens
-
Kohl W, Gloe A, Reichenbach H: Steroids from the myxobacterium Nannocystis exedens. J Gen Microbiol (1983) 129:1629- 1635.
-
(1983)
J Gen Microbiol
, vol.129
, pp. 1629-1635
-
-
Kohl, W.1
Gloe, A.2
Reichenbach, H.3
-
99
-
-
0037039963
-
Biosynthesis of zeaxanthin via mevalonate in Paracoccus species strain PTA-3335. A product-based retrobiosynthetic study
-
Eisenreich W, Bacher A, Berry A, Bretzel W, Hümbelin M, Lopez-Ulibarri R, Mayer AF, Yeliseev A: Biosynthesis of zeaxanthin via mevalonate in Paracoccus species strain PTA-3335. A product-based retrobiosynthetic study. J Org Chem (2002) 67(3):871-875.
-
(2002)
J Org Chem
, vol.67
, Issue.3
, pp. 871-875
-
-
Eisenreich, W.1
Bacher, A.2
Berry, A.3
Bretzel, W.4
Hümbelin, M.5
Lopez-Ulibarri, R.6
Mayer, A.F.7
Yeliseev, A.8
|