Tools for discovery of inhibitors of the 1-deoxy-D-xylulose 5-phosphate (DXP) synthase and DXP reductoisomerase: An approach with enzymes from the pathogenic bacterium Pseudomonas aeruginosa

FEMS Microbiology Letters

Volumn 190, Issue 2, 2000, Pages 329-333

  Altincicek, Boran ^a   Hintz, Martin ^a   Sanderbrand, Silke ^a   Wiesner, Jochen ^a   Beck, Ewald ^a   Jomaa, Hassan ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

1 Deoxy D xylulose 5 phosphate reductoisomerase; 1 Deoxy D xylulose 5 phosphate synthase; Inhibitor; Pseudomonas aeruginosa

Indexed keywords

1 DEOXY D XYLULOSE 5 PHOSPHATE REDUCTOISOMERASE; 1 DEOXY D XYLULOSE 5 PHOSPHATE SYNTHASE; BACTERIAL ENZYME; FOSMIDOMYCIN; ISOPRENOID; MEVALONIC ACID; PYRUVIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA;

ALDOSE-KETOSE ISOMERASES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; ESCHERICHIA COLI; FOSFOMYCIN; HUMANS; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; OXIDOREDUCTASES; PSEUDOMONAS AERUGINOSA; PYRUVATES; SPECTROPHOTOMETRY; TRANSFERASES;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA;

EID: 0034666627     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(00)00357-8     Document Type: Article

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