Formation of 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol from 2-C- methyl-D-erythritol 4-phosphate by 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, a new enzyme in the nonmevalonate pathway

Tetrahedron Letters

Volumn 41, Issue 5, 2000, Pages 703-706

  Kuzuyama, Tomohisa ^a   Takagi, Motoki ^a   Kaneda, Kazuhide ^a   Dairi, Tohru ^b   Seto, Haruo ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b TOYAMA PREFECTURAL UNIVERSITY   (Japan)

Author keywords

2 C methyl D erythritol 4 phosphate; 2 C methyl D erythritol 4 phosphate cytidylyltransferase; 4 (cytidine 5' diphospho) 2 C methyl D erythritol; Isopentenyl diphosphate

Indexed keywords

CYTIDINE TRIPHOSPHATE; ERYTHRITOL; MEVALONIC ACID; TRANSFERASE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; ESCHERICHIA COLI; NONHUMAN; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS;

EID: 0034728128     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)02143-7     Document Type: Article

References (6)

1. Rohmer, M. In Comprehensive Natural Products Chemistry; Barton, D.; Nakanishi, K., Eds. Isoprenoids including carotenoids and steroids. Elsevier: Amsterdam, 1999; Vol. 2, pp. 45-67.
2. Kuzuyama, T.; Takahashi, S.; Watanabe, H.; Seto, H. Tetrahedron Lett. 1998, 39, 4509-4512.
3. Takahashi, S.; Kuzuyama, T.; Watanabe, H.; Seto, H. Proc. Natl. Acad. Sci. USA 1998, 95, 9879-9884.
4. Kuzuyama, T.; Shimizu, T.; Takahashi, S.; Seto, H. Tetrahedron Lett. 1998, 39, 7913-7916.
5. Takagi, M.; Kuzuyama, T.; Kaneda, K.; Dairi, T.; Seto, H., submitted for publication.
6. Takagi, M.; Kuzuyama, T.; Takahashi, S.; Seto, H., submitted for publication.