An Anacardiaceae preparation reduces the expression of inflammation-related genes in murine macrophages

International Immunopharmacology

Volumn 4, Issue 8, 2004, Pages 991-1003

  Leiro, J ^a   Garcia D ^b   Arranz, J A ^a   Delgado, R ^b   Sanmartin M L ^a   Orallo, F ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b Laboratorio Central de Farmacologia   (Cuba)

Author keywords

activator protein 1; AP 1; constitutive cyclooxygenase; COX 1; COX 2; dexamethasone; DMEM; Dulbecco's Modified Eagle's medium; DX; ELISA; inducible cyclooxygenase; Mangifera indica extract; mRNA; Murine macrophages; NOS 2; Pro inflammatory cytokines

Indexed keywords

ANTIINFLAMMATORY AGENT; CANCER GROWTH FACTOR; CYCLOOXYGENASE 2; FATTY ACID; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MANGIFERA INDICA EXTRACT; MANGIFERIN; MESSENGER RNA; PLANT EXTRACT; POLYPHENOL DERIVATIVE; PROSTAGLANDIN E2; STEROID; TRANSFORMING GROWTH FACTOR BETA1; TRITERPENE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VIMANG;

ANACARDIACEAE; ANIMAL MODEL; ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG EFFECT; DRUG INHIBITION; DRUG SYNTHESIS; GENE EXPRESSION; IN VITRO STUDY; INFLAMMATION; MACROPHAGE; MANGO; MEDICINAL PLANT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REDUCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL SURVIVAL; CYTOKINES; DEXAMETHASONE; GENE EXPRESSION; INFLAMMATION MEDIATORS; INTERFERON TYPE II; LIPOPOLYSACCHARIDES; MACROPHAGES, PERITONEAL; MANGIFERA; MICE; MICE, INBRED BALB C; PLANT BARK; PLANT EXTRACTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; XANTHONES;

EID: 3042662013     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2004.02.003     Document Type: Article

References (52)

1. Stafford J.L., Neumann N.F., Belosevic M. Macrophage-mediated innate host defense against protozoan parasites. Crit. Rev. Microbiol. 28:2002;187-248
2. Underhil D.M., Ozinsky A. Phagocytosis of microbes: complexity in action. Annu. Rev. Immunol. 20:2002;825-852
3. Gougerot-Pocidalo M.A., el Benna J., Elbim C., Chollet-Martin S., Dang M.C. Regulation of human neutrophil oxidative burst by pro- and anti-inflammatory cytokines. Soc. Biol. 196:2002;37-46
4. MacMicking J., Xie Q.W., Nathan C. Nitric oxide and macrophage function. Annu. Rev. Immunol. 15:1997;323-350
5. MacMicking J.D., North R.J., LaCourse R., Mudgett J.S., Shah S.K., Nathan C.F. Identification of nitric oxide synthase as a protective locus against tuberculosis. Proc. Natl. Acad. Sci. U. S. A. 94:1997;5243-5248
6. Nie D., Honn K.V. Cyclooxygenase, lipoxygenase and tumor angiogenesis. Cell. Mol. Life Sci. 59:2002;799-807
7. Menter D.G. Cyclooxygenase 2 selective inhibitors in cancer treatment and prevention. Expert Opin. Investig. Drugs. 11:2002;1749-1764
8. Salvemini D., Wang Z.Q., Wyatt P.S., Bourdon D.M., Marino M.H., Manning P.T., et al. Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation. Br. J. Pharmacol. 118:1996;829-838
9. Elenkov I.J., Chrousos G.P. Stress hormones, proinflammatory and antiinflammatory cytokines, and autoimmunity. Ann. N. Y. Acad. Sci. 966:2002;290-303
10. Rahman I. Oxidative stress, transcription factors and chromatin remodelling in lung inflammation. Biochem. Pharmacol. 64:2002;935-942
11. Center of Pharmaceutical Chemistry. Pharmaceutical compositions including a mixture of polyphenols, terpenoids, steroids, fatty acids and microelements with antioxidant, analgesic, antiinflammatory and antispasmodic properties. Patent Pending 203/98, OCP, Havana, Cuba, 1988.
12. Núñez Selles A.J., Velez Castro H.T., Aguero-Aguero J., Gonzalez-Gonzalez J., Naddeo F., De Simone F., et al. Isolation and quantitative analysis of phenolic antioxidants, free sugars, and polyols from mango (Mangifera indica L.) stem bark aqueous decoction used in Cuba as a nutritional supplement. J. Agric. Food Chem. 50:2002;762-766
13. García D., Delgado R., Ubeira F.M., Leiro J. Modulation of rat macrophage function by the Mangifera indica L. extracts Vimang and mangiferin. Int. Immunopharmacol. 2:2002;797-806
14. Dostal D.E., Kempinski A.M., Motel T.J., Baker K.M. Absolute quantification of messenger RNA using multiplex RT-PCR. Siebert P.D., Larrick J.W. Gene Cloning and Analysis by RT-PCR. 1998;71-90 BioTechniques Books, Natick (MA)
15. Leiro J., Álvarez E., Arranz J.A., Siso I.G., Orallo F. In vitro effects of mangiferin on superoxide concentrations and expression of the inducible nitric oxide synthase, tumor necrosis factor-alpha and transforming growth factor-beta genes. Biochem. Pharmacol. 65:2003;1361-1371
16. Korhonen R., Lahti A., Hamalainen M., Kankaanranta H., Moilanen E. Dexamethasone inhibits inducible nitric-oxide synthase expression and nitric oxide production by destabilizing mRNA in lipopolysaccharide-treated macrophages. Mol. Pharmacol. 62:2002;698-704
17. Fernández-Morata J.C., Mullol J., Fuentes M., Pujols L., Roca-Ferrer J., Pérez M., et al. Regulation of cyclooxygenase-1 and -2 expression in human nasal mucosa. Effects of cytokines and dexamethasone. Clin. Exp. Allergy. 30:2000;1275-1284
18. Martínez J., Moreno J.J. Effect of resveratrol, a natural polyphenolic compound, on reactive oxygen species and protaglandin production. Biochem. Pharmacol. 59:2000;865-870
19. Levine S.J., Larivee P., Logun C., Angus C.W., Shelhamer J.H. Corticosteroids differentially regulate secretion of IL-6, IL-8, and G-CSF by a human bronchial epithelial cell line. Am. J. Physiol. 265:1993;L360-L368
20. Van der Burg B., van der Saag P.T. Nuclear factor-kappa-B/steroid hormone receptor interactions as a functional basis of anti-inflammatory action of steroids in reproduction organs. Mol. Hum. Reprod. 2:1996;433-438
21. Simoncini T., Maffei S., Basta G., Barsacchi G., Genazzani A.R., Liao J.K., et al. Estrogens and glucocorticoids inhibit endothelial vascular cell adhesion molecule-1 expression by different transcriptional mechanisms. Circ. Res. 87:2000;19-25
22. Darley-Usmar V., Wiseman H., Halliwell B. Nitric oxide and oxygen radicals: a question of balance. FEBS Lett. 369:1995;131-135
23. Gross S.S., Wolin M.S. Nitric oxide: pathophysiological mechanisms. Annu. Rev. Physiol. 57:1995;737-769
24. T. Michel, Q.-W. Xie, C. Nathan, Molecular biological analysis of nitric oxide synthases. In: M. Feelisch, J.S. Stamler (Eds.), Methods in Nitric Oxide Research, Wiley, Chichester, pp. 161-175.
25. Xie Q.-W., Cho H., Calaycay J., Mumford R.A., Swiderek K.M., Lee T.D., et al. Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. Science. 256:1992;225-228
26. Lin Y.L., Lin J.K. (-)-Epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear-kappa B. Mol. Pharmacol. 52:1997;465-472
27. Xiong O., Tezuka Y., Kaneko L., Li H., Tran L.Q., Hase K., et al. Inhibition of nitric oxide by phenylethanoids in activated macrophages. Eur. J. Pharmacol. 14:2000;137-144
28. Chen Y., Yang L., Lee T.J. Oroxylin A inhibition of lipopolysaccharide- induced iNOS and COX-2 gene expression via suppression of nuclear factor-kappa B activation. Biochem. Pharmacol. 59:2000;1445-1457
29. Ahmed S., Rahman A., Hasnain A., Lalonde M., Goldberg V.M., Haqqi T.M. Green tea polyphenol epigallocatechin-3-gallate inhibits the IL-1 beta-induced activity and expression of cyclooxygenase-2 and nitric oxide synthase-2 in human chondrocytes. Free Radic. Biol. Med. 33:2002;1097-1105
30. Eliopoulos A.G., Dimitru C.D., Wang C.-C., Cho J., Tsichlis P.N. Induction of COX-2 by LPS in macrophages is regulated by Tp12-dependent CREB activation signals. EMBO J. 21:2002;4831-4840
31. Herschman H.R. Prostaglandin synthase 2. Biochim. Biophys. Acta. 1299:1996;125-140
32. Caivano M., Cohen P. Role of mitogen-activated protein kinase cascades in mediating lipopolysaccharide-stimulated induction of cyclooxygenase-2 and IL-1β in RAW264 macrophages. J. Immunol. 164:2000;3018-3025
33. Perkins D.J., Kniss D.A. Blockade of nitric oxide formation down-regulates cyclooxygenase-2 and decreases PGE2 biosynthesis in macrophages. J. Leukoc. Biol. 65:1999;792-799
34. Attur M.G., Patel R., Thakker G., Vyas P., Levartovski D., Patel P., et al. Differential anti-inflammatory effects of immunosuppressive drugs: cyclosporine, rapamycin and FK-506 on inducible nitric oxide synthase, nitric oxide, cyclooxygenase-2 and PGE2 production. Inflamm. Res. 49:2000;20-29
35. Hong J., Smith T.J., Ho C.T., August D.A., Yang C.S. Effects of purified green and black tea polyphenols on cyclooxygenase- and lipoxygenase-dependent metabolism of arachidonic acid in human colon mucosa and colon tumor tissues. Biochem. Pharmacol. 62:2001;1175-1183
36. Feldmann M., Brennan F.M., Maini R.N. Role of cytokines in rheumatoid arthritis. Annu. Rev. Immunol. 14:1996;397-440
37. Alvaro-García J.M., Zvaifler N.J., Brown C.B., Kaushansky L., Firestein G.S. Cytokines in chronic inflammatory arthritis: VI. Analysis of the synovial cells involved in granulocyte-macrophage colony stimulating factor production and gene expression in rheumatoid arthritis and its regulation by IL-1 and TNF-α J. Immunol. 146:1991;3365-3371
38. Crouvezier S., Powell B., Keir D., Yaqoob P. The effects of phenolic components of tea on the production of pro- and anti-inflammatory cytokines by human leukocytes in vitro. Cytokine. 13:2001;280-286
39. Haworth C., Brennan F.M., Chantry D., Turner M., Maini R.N., Feldmann M. Expression of granulocyte-macrophage colony-stimulating factor in rheumatoid arthritis: regulation by tumor necrosis factor-α Eur. J. Immunol. 21:1991;2575-2579
40. Butler D., Maini R.N., Feldmann M., Brennan F.M. Blockade of TNF with chimeric anti TNF monoclonal antibody, cA2 reduces (IL-6 and IL-8) release in RANMC cultures: a comparison with IL-1ra. Eur. Cytokine Netw. 6:1995;225-230
41. Yang F., de Villiers W.J., McClain C.J., Varilek G.W. Green tea polyphenols block endotoxin-induced tumor necrosis factor-production and lethality in murine model. J. Nutr. 128:1998;2334-2340
42. Suganuma M., Sueoka E., Sueoka N., Okabe S., Fujiki H. Mechanisms of cancer prevention by tea polyphenols based on inhibition of TNF-alpha expression. Biofactors. 13:2000;67-72
43. Joyce D.A., Steer J.H., Abraham L.J. Glucocorticoid modulation of human monocyte/macrophage function: control of TNF-alpha secretion. Inflamm. Res. 46:1997;447-451
44. Ghosh S., May M.J., Kopp E.B. NF-κB and Rel proteins: evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. 16:1998;225-260
45. Baldwin A.S. Jr. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu. Rev. Immunol. 14:1996;649-683
46. Callejas N.A., Casado M., Bosca L., Martin-Sanz P. Requirement of nuclear factor kappaB for the constitutive expression of nitric oxide synthase-2 and cyclooxygenase-2 in rat trophoblasts. J. Cell Sci. 112:1999;3147-3155
47. Wadleigh D.J., Reddy S.T., Kopp E., Ghosh S., Herschman H.R. Transcriptional activation of the cyclooxygenase-2 gene in endotoxin-treated RAW 264.7 macrophages. J. Biol. Chem. 275:2000;6259-6266
48. Tomita M., Irwin K.I., Xie Z.J., Santoro T.J. Tea pigments inhibit the production of type 1 (T(H1)) and type 2 (T(H2)) helper T cell cytokines in CD4(+) T cells. Phytother. Res. 16:2002;36-42
49. Singh R., Ahmed S., Islam N., Goldberg V.M., Haqqi T.M. Epigallocatechin-3-gallate inhibits interleukin-1beta-induced expression of nitric oxide synthase and production of nitric oxide in human chondrocytes: suppression of nuclear factor kappa B activation by degradation of the inhibitor of nuclear factor kappa B. Arthritis Rheum. 46:2002;2079-2086
50. Lovites Y., Youdin M.B., Maor G., Mandel S. Attenuation of 6-hydroxydopamine (6-OHDA)-induced nuclear factor-kappa B (NF-kappaB) activation and cell death by tea extracts in neuronal cultures. Biochem. Pharmacol. 63:2002;21-29
51. Zhong Z., Froh M., Connor H.D., Li X., Conzelmann L.O., Mason R.P., et al. Prevention of hepatic ischaemia-reperfusion injury by green tea extract. Am. J. Physiol. Gastrointest. Liver Physiol. 283:2002;G957-G964
52. Tanaka S., Sakata Y., Morimoto K., Tambe Y., Watanabe Y., Honda G., et al. Influence of natural and synthetic compounds on cell surface molecules, ICAM-1 and VCAM-1. Planta Med. 67:2001;108-113