Inhibition of MAP kinases by crude extract and pure compound isolated from Commiphora mukul leads to down regulation of TNF-α, IL-1β and IL-2

International Immunopharmacology

Volumn 6, Issue 2, 2006, Pages 122-132

  Manjula, N ^a   Gayathri, B ^a   Vinaykumar, K S ^a   Shankernarayanan, N P ^c   Vishwakarma, R A ^b   Balakrishnan, A ^a  

^a ANNA UNIVERSITY   (India)

^b JAWAHARLAL NEHRU UNIVERSITY   (India)

^c VHS Leprosy Research Centre   (India)

Author keywords

Commiphora mukul; MAPK; Proinflammatory cytokines

Indexed keywords

ACETIC ACID ETHYL ESTER; COMMIPHORA EXTRACT; GAMMA INTERFERON; GUGGULSTEROL; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PLANT EXTRACT; PROTEIN C FOS; PROTEIN C JUN; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BIOASSAY; COMMIPHORA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECT; DRUG ISOLATION; DRUG STRUCTURE; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LYMPHOCYTE PROLIFERATION; MEDICINAL PLANT; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL;

ACETATES; ANIMALS; BLOTTING, WESTERN; CELL PROLIFERATION; COMMIPHORA; DOWN-REGULATION; GENES, FOS; GENES, JUN; HUMANS; INDICATORS AND REAGENTS; INTERLEUKIN-1; INTERLEUKIN-2; LYMPHOCYTE CULTURE TEST, MIXED; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PHYTOHEMAGGLUTININS; PLANT EXTRACTS; RNA, MESSENGER; SOLVENTS; TETRAZOLIUM SALTS; THIAZOLES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 30144438848     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2005.07.001     Document Type: Article

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