CD14+CD16++ cells derived in vitro from peripheral blood monocytes exhibit phenotypic and functional dendritic cell-like characteristics

European Journal of Immunology

Volumn 30, Issue 7, 2000, Pages 1872-1883

  Ancuta, Petronela ^a   Weiss, Laurence ^a   Haeffner Cavaillon, Nicole ^a  

^a HÔPITAL BROUSSAIS   (France)

Author keywords

Cellular differentiation; Cytokine; Dendritic cell; Human monocyte; Macrophage

Indexed keywords

B7 ANTIGEN; CD1 ANTIGEN; CD11B ANTIGEN; CD14 ANTIGEN; CD16 ANTIGEN; CD18 ANTIGEN; CD40 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; GLYCOPROTEIN P 15095; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HLA DR ANTIGEN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LEUKOCYTE CULTURE; LYMPHOCYTE PROLIFERATION; MONOCYTE; NONHUMAN; NORMAL HUMAN; PHENOTYPE; PRIORITY JOURNAL; RIBONUCLEASE PROTECTION ASSAY; T LYMPHOCYTE;

ANTIGEN PRESENTATION; ANTIGENS, CD14; ANTIGENS, CD40; CD40 LIGAND; CELLS, CULTURED; CYTOKINES; DENDRITIC CELLS; FLOW CYTOMETRY; GRANULOCYTE MACROPHAGE COLONY-STIMULATING FACTORS, RECOMBINANT; HUMANS; IMMUNOPHENOTYPING; INTERLEUKIN-10; INTERLEUKIN-12; INTERLEUKIN-4; KINETICS; MEMBRANE GLYCOPROTEINS; MONOCYTES; RECEPTORS, IGG; RNA, MESSENGER;

EID: 0033935467     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200007)30:7<1872::AID-IMMU1872>3.0.CO;2-2     Document Type: Article

References (50)

1. + subpopulation. Immunol. Today 1996. 17: 424-430.
2. Elbim, C., Hakim, J. and Gougerot-Pocidalo, M. A., Heterogeneity in Lewis-X and Siallyl-Lewis-X antigen expression on monocytes in whole blood. Am. J. Pathol. 1998. 152: 1081-1090.
3. Thomas, R. and Lipsky, E. P., Human peripheral blood dendritic cell subsets. J. Immunol. 1994. 153: 4016-4028.
4. + blood monocytes exhibits features of tissue macrophages. Eur. J. Immunol. 1993. 23: 2053-2058.
5. high: a cytokine-producing monocyte subset which expands during human immunodeficiency virus infection. Eur. J. Immunol. 1995. 25: 3418-3424.
6. + monocytes subpopulation in patients with acute and chronic infections undergoing hemodialysis. Infect. Immun. 1998. 66: 2782-2790.
7. Pio, R., Lopez-Zabalza, M. J., Rouzaut, A., Santiago, E. and Lopez-Moratalla, N., Nitric oxide activates granule-associated DNase in human monocytes. Nitrix oxide. 1998. 2: 165-173.
8. + monocytes by glucocorticoid therapy. Clin. Exp. Immunol. 1998. 112: 501-506.
9. + monocytes in critically ill cardiac surgery patients. Inflammation 1998. 22: 367-379.
10. + monocytes in human sepsis: a case report of a patient with self-induced septicemia. Shock. 1997. 8: 73-75.
11. Marshall, G. D., Agarwal, S. K., Lloyd, C., Cohen, L., Henninger, E. M. and Morris, G. J., Cytokine dysregulation associated with exam stress in healthy medical students. Brain Behav. Immun. 1998. 12: 297-307.
12. Frankenberger, M., Sternsdorf, T., Pechumer, H., Pforte, A. and Ziegler-Heitbrock, H. W. L. M., Differential cytokine expression in human blood monocytes subpopulation: a polymerase chain reaction analysis. Blood 1996. 87: 373-377.
13. Hart, D. N. J., Dendritic cells: unique leukocyte populations which control the primary immune response. Blood 1997. 90: 3245-3287.
14. Schäkel, K., Mayer, E., Federle, C., Schmitz, M., Riethmüller, G. and Rieber, E. P., A novel dendritic cell population in human blood: one-step immunomagnetic isolation by a specific mAb (M-DC8) and in vitro priming of cytotoxic T lymphocytes. Eur. J. Immunol. 1998. 28: 4084-4093.
15. Pulliam, L., Gascon, R., Subblebine, M., McGuire, D. and McGrath, M. S., Unique monocyte subset in patients with AIDS dementia. Lancet 1997. 349: 692-695.
16. Sonza, S., Maerz, A., Deacon, N., Meanger, J., Mills, J. and Crowe, S., Human immunodeficiency virus type 1 replication is blocked prior to reverse transcription and integration in freshly isolated peripheral blood monocytes. J. Virol. 1996. 70: 3863-3869.
17. Gendelman, H. E., Lipton, S., Tardieu, M., Genis, P., Jett, M., Zhai, J. and Nottet, H., The neuropathogenesis of HIV-infection. J. Leukoc. Biol. 1994. 56: 389-399.
18. Ghorpade, A., Xia, M. Q., Hyman, B. T., Persidsky, Y., Nukuna, A., Bock, P., Che, M., Limoges, J., Gendelman, H. E. and Mackay, C. R., Role of the beta-chemokine receptors CCR3 and CCR5 in human immunodeficiency virus type 1 infection of monocytes and microglia. J. Virol. 1998. 72: 3351-3361.
19. Verani, A., Pesenti, E., Polo, S., Tresoldi, E., Scarlatti, G., Lusso, P., Siccardi, A. G. and Vercelli, D., CXCR4 is a functional coreceptor for infection of human macrophages by CXCR4-dependent primary HIV-1 isolates. J. Immunol. 1998. 161: 2084-2088.
20. Zoeteweij, J. P., Golding, H., Mostowski, H. and Blauvelt, A., Cytokines regulate expression and function of the HIV coreceptor CXCR4 on human mature dendritic cells. J. Immunol. 1998. 161: 3219-3223.
21. Canque, B., Bakri, Y., Camus, S., Yagello, M., Benjouad, A. and Gluckman, J. C., Susceptibility of dendritic cells (DC) to HIV is primarily determined by their maturation stage. J. Leukoc. Biol. 1998. supplement 2: 20-28.
22. Weissman, D., Li, Y., Orenstein, J. M. and Fauci, A. S., Both a precursor and a mature population of dendritic cells can bind HIV. J. Immunol. 1995. 155: 4111-4117.
23. Stent, G., Joo, G. B., Kierulf, P. and Asjo, B., Macrophage tropism: fact or fiction? Leukoc. Biol. 1997. 6: 4-11.
24. Kruger, M., Winkel, J. G. V. D., Wit, T. P. D., Coorevits, L. and Ceuppens, J. L., Granulocyte-macrophage colony-stimulating factor down-regulates CD14 expression on monocytes. Immunol. 1996. 89: 89-96.
25. Ruppert, J., Friedrichs, D., Xu, H. and Peters, J. H., IL-4 decreases the expression of the monocyte differentiation marker CD14, paralleled by an increasing accessory potency. Immunobiology. 1991. 182: 449-464.
26. Ruppert, J., Schutt, D., Ostermaie, D. and Peters, J. H., Down-regulation and release of CD14 on human monocytes by IL-4 depends on the presence of serum or GM-CSF. Adv. Exp. Med. Biol. 1993. 329: 281-290.
27. Rieser, C., Ramoner, R., Bock, G., Deo, Y. M., Holtl, L., Bartsch, G. and Thurnher, M., Human monocyte-derived dendritic cells produce macrophage colony-stimulating factor: enhancement of c-fms expression by interleukin-10. Eur. J. Immunol. 1998. 28: 2283-2288.
28. Romani, N., Reider, D., Heuer, M., Ebner, S., Kämpgen, E., Eibl, B. and Schuler, D. N. G., Generation of mature dendritic cells from human blood. An improved method with special regard to clinical applicability. J. Immunol. Methods 1996. 196: 137-151.
29. Morel, A. S., Quaratino, S., Douek, D. C. and Londei, M., Split activity of interleukin-10 on antigen capture and antigen presentation by human dendritic cells: definition of a maturative step. Eur. J. Immunol. 1997. 27: 26-34.
30. Allavena, P., Piemonti, L., Longoni, D., Bernasconi, S., Stoppacciaro, A., Ruco, L. and Mantovani, A., IL-10 prevents the differentiation of monocytes to dendritic cells but promotes their maturation to macrophages. Eur. J. Immunol. 1998, 28: 359-369.
31. Chapuis, F. O., Rosenzwajg, M., Yagello, M., Ekmen, M., Biberfeld, P. and Gluckman, J. C., Differentiation of human dendritic cells from monocytes in vitro. Eur. J. Immunol. 1997. 27: 431-441.
32. + peripheral blood monocytes. J. Immunol. 1996. 157: 3850-3859.
33. Cella, M., Scheidegger, D., Palmer-Lehman, K., Lane, P., Lanzavecchia, A. and Albert, G., Ligation of CD40 on dendritic cells triggers production of high levels of IL-12 and enhances T cell stimulatory capacity: T-T help via APC activation. J. Exp. Med. 1996. 184: 747-752.
34. McDyer, J. F., Goletz, T. J., Thomas, E., June, C. H. and Seder, R. A., CD40 ligand/CD40 stimulation regulates the production of IFN-gamma from human peripheral blood monomoclear cells in an IL-12- and/or CD28-dependent manner. J. Immunol. 1998. 160: 1701-1707.
35. Rissoan, M. C., Soumelis, V., Kadowaki, N., Grouard, G., Briere, F., de Waal Melefyt, R. and Liu, Y. J., Reciprocal control of T helper cell and dendritic cell differentiation. Science 1999. 283: 1183-1186.
36. Dieu, M.-C., Vanbervliet, B. A., Vicari, A., Bridon, J.-M., Oldham, E., Aït-Yahia, S., Brière, F., Zlotnik, A., Lebecque, S. and Caux, C., Selective recruitement of immature and mature dendritic cells by distinct chemolines expressed in different anatomic sites. J. Exp. Med. 1998. 188: 373-386.
37. Nottet, H. S., Persidsky, Y., Sasseville, V. G., Nukuna, A. N., Bock, P., Zhai, Q. H., Sharer, L. R., McComb, R. D., Swindells, S., Soderland, C. and Gendelman, H. E., Mechanisms for the transendothelial migration of HIV-1-infected monocytes into brain. J. Immunol. 1996. 156: 1284-1295.
38. Hashimoto, S., Yamada, M., Motoyoshi, K. and Akagawa, K. S., Enhancement of macrophage colony-stimulating factor-induced growth and differentiation of human monocytes by interleukin-10. Blood 1997. 89: 315-321.
39. Sozzani, S., Ghezzi, S., Iannolo, G., Luini, W., Borsatti, A., Polentarutti, N., Sica, A., Locati, M., Mackay, C., Wells, T. N., Biswas, P., Vicenzi, E., Poli, G. and Mantovani, A., Interleukin 10 increases CCR5 expression and HIV infection in human monocytes. J. Exp. Med. 1998. 187: 439-444.
40. Wang, J., Roderiquez, G., Oravecz, T. and Norcross, M. A., Cytokine regulation of human immunodeficiency virus type 1 entry and replication in human monocytes/macrophages through modulation of CCR5 expression. J. Virol. 1998. 72: 7642-7647.
41. Palucka, K. A., Taquet, N., Sanchez-Chapuis, F. and Gluckman, J. C., Dendritic cells as terminal stage of monocyte differentiation. J. Immunol. 1998. 160: 4587-4595.
42. Wahl, S. M., Hunt, D. A., Wakefield, L. M., McCartney-Francis, N., Wahl, L. M., Roberts, A. B. and Sporn, M. B., Transforming growth factor β (TGF-β) induces monocyte chemotaxis and growth factor production. Proc. Natl. Acad. Sci. USA 1987. 84: 5788-5798.
43. Begley, C. G. and Nicola, N. A., Resolving conflicting signals: cross inhibition of cytokine signaling pathways. Blood 1999. 93: 1443-1447.
44. Kalinski, P., Schuitemaker, J. H. N., Hilkens, C. M. U., Wierenga, E. A. and Kapsenberg, M. L., Final maturation of dendritic cells is associated with impaired responsiveness to IFN-γ and to bacterial IL-12 inducers: decreased ability of mature dendritic cells to produce IL-12 during the interaction with Th cells. J. Immunol. 1999. 162: 3231-3236.
45. Saint-Vis, B. D., Fugier-Vivier, Massacrier, C., Gaillard, C., Vanbervliet, B. A., Aït-Yahia, S., I., Banchereau, J., Liu, Y.-J., Lebecque, S. and Caux, C., The cytokine profile expressed by human dendritic cells is dependent on cell subtype and mode of activation. J. Immunol. 1998. 160: 1666-1676.
46. Steinbrink, K., Wölfl, M., Jonuleit, H., Knop, J. R. and Enk, A. H., Induction of tolerance by IL-10-treated dendritic cells. J. Immunol. 1997. 159: 4772-4780.
47. Weiss, L., Haeffner-Cavaillon, N., Laude, M., Gilquin, J. and Kazatchkine, M. D., HIV infection is associated with the spontaneous production of interleukin-1 (IL-1) in vivo and with an abnormal release of IL-1 alpha in vitro. AIDS 1989. 3: 695-699.
48. + dendritic cells. Proc. Natl. Acad. Sci. USA 1996. 93: 2588-2592.
49. + leukocytes acquire the phenotype and function of antigen-presenting dendritic cells when cultured in GM-CSF and IL-4. J. Leukoc. Biol. 1996. 59: 208-218.
50. Estcourt, C., Rousseau, Y., Sadeghi, H. M., Thiéblemont, N., Carreno, M. P., Weiss, L. and Haeffner-Cavaillon, N., Flowcytometric assessment of in vivo cytokine-producing monocytes in HIV-infected patients. Clin. Immunol. Immunopathol. 1997. 83: 60-67.